Effect of advancing gestational age on the frequency of fetal ductal constriction in association with maternal indomethacin use.

Abstract:

OBJECTIVE:The objective of this study was to determine whether indomethacin is associated with an increased incidence of constriction of the human fetal ductus arteriosus with advancing gestational age. STUDY DESIGN:A retrospective analysis of fetal echocardiograms performed in 44 patients with premature labor or hydramnios treated with indomethacin (25 mg orally every 6 hours) was undertaken. Fisher's exact test, Kaplan-Meier survival analysis, and log-rank techniques were used; a value of p < 0.05 was considered statistically significant. RESULTS:The frequency of ductal constriction was similar for fetuses of singleton and multiple gestations. A dramatic increase in constriction was noted at 32 weeks' gestation when the rate of compromise approached 50%. CONCLUSIONS:The use of indomethacin should be restricted to gestational ages of < 32 weeks. In multiple gestations each fetus should be evaluated by echocardiography, because the ductal response may vary between individual fetuses.

journal_name

Am J Obstet Gynecol

authors

Moise KJ Jr

doi

10.1016/s0002-9378(11)90763-7

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

1350-3

issue

5

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(11)90763-7

journal_volume

168

pub_type

杂志文章
  • The effect of the prostaglandin F compounds on the contractility of the pregnant human uterus.

    abstract::The aim of this paper was to study the influence of prostaglandins compounds on the pregnant human uterus in situ. Recordings of uterine motility were made on 14 pregnant women by measuring the amniotic pressure. PGE1 alpha and PGF2 alpha were administered intravenously as single injections. It was found that PGF2 ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(70)90042-6

    authors: Bygdeman M,Kwon SU,Mukherjee T,Roth-Brandel U,Wiqvist N

    更新日期:1970-02-15 00:00:00

  • Toxic shock syndrome: an update.

    abstract::Since late 1979 to early 1980, when toxic shock syndrome achieved notoriety, a substantial body of data has demonstrated that vaginal Staphylococcus aureus infections, particularly those occurring during menstruation, account for most cases of toxic shock syndrome in women of reproductive age. Among those patients wit...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1016/s0002-9378(12)90734-6

    authors: Reingold AL

    更新日期:1991-10-01 00:00:00

  • Iatrogenic prematurity due to elective termination of the uncomplicated pregnancy: a major perinatal health care problem.

    abstract::In a series of 1,000 newborn infants referred to a regional neonatal center, 32 iatrogenically preterm infants were identified. All had been delivered following elective termination of uncomplicated, apparently term pregnancies, without prior documentation of fetal lung maturity or ultrasonic determination of fetal bi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90717-2

    authors: Flaksman RJ,Vollman JH,Benfield DG

    更新日期:1978-12-15 00:00:00

  • Successful pregnancy outcomes after amniotic fluid embolism.

    abstract::Two patients who survived cardiorespiratory arrest occurring in association with amniotic fluid embolism syndrome were seen during the subsequent pregnancy. Both had uneventful pregnancies and delivered at term without complications. These are the only case reports of pregnancy after amniotic fluid embolism, and they ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)91442-2

    authors: Clark SL

    更新日期:1992-08-01 00:00:00

  • Monolayer and suspension culture of human prolactin-secreting pituitary adenoma.

    abstract::In order to study the hormonal characteristics of human prolactin-secreting pituitary adenomas, in vitro monolayer and suspension cultures from human pituitary glands were established. Optimal conditions for cultures included enzymatic dispersion into viable single-cell suspensions with the use of 1% collagenase in ph...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(80)90084-8

    authors: Kletzky OA,Marrs RP,Rundall TT,Weiss MH,Beierle JW

    更新日期:1980-11-15 00:00:00

  • Fetal umbilical artery Doppler response to graded maternal aerobic exercise and subsequent maternal mean arterial blood pressure: predictive value for pregnancy-induced hypertension.

    abstract::Predictive tests for the identification of women at high risk of the development of preeclampsia are critical to allow the most appropriate preventive measures. Preeclampsia is a vasospastic condition of pregnancy characterized by early and enhanced vascular reactivity to endogenous pressor agents. Exercise tolerance ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)91077-p

    authors: Hume RF Jr,Bowie JD,McCoy C,Magarelli PC,Gall M,Hertzberg BS,Carroll BA,Killam AP

    更新日期:1990-09-01 00:00:00

  • Vaginal fetal fibronectin as a predictor of spontaneous preterm delivery in the patient with cervical cerclage.

    abstract:OBJECTIVE:The purpose of this study was to assess the validity of vaginal fetal fibronectin as a screening test for spontaneous preterm birth in patients with cervical cerclage. STUDY DESIGN:A historic cohort of 117 patients who underwent cervical cerclage placement between 1996 and 2002 were identified. All patients ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/s0002-9378(03)00656-2

    authors: Roman AS,Rebarber A,Sfakianaki AK,Mulholland J,Saltzman D,Paidas MJ,Minior V,Lockwood CJ

    更新日期:2003-11-01 00:00:00

  • Influence of labor on fetoplacental adrenomedullin concentrations.

    abstract:OBJECTIVE:Circulating adrenomedullin is increased in pregnancy, and placental and fetal membranes participate significantly in its secretion. Recent studies have suggested a potential role for this peptide in the regulation of fetoplacental circulation and placental hormonal secretion. Because adrenomedullin acts also ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2001.117189

    authors: Di Iorio R,Marinoni E,Letizia C,Alò P,Villaccio B,Poverini R,Cosmi EV

    更新日期:2001-09-01 00:00:00

  • Asymptomatic shedding of herpesvirus during labor.

    abstract::Cervical cultures of 2013 consecutive obstetric patients with no history of genital herpes simplex virus infection were used to determine the frequency of asymptomatic herpes simplex virus shedding in labor. Four (0.20%) of these patients had positive cultures. None of the exposed neonates developed clinical evidence ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90034-8

    authors: Simkovich JW,Soper DE

    更新日期:1988-03-01 00:00:00

  • Misoprostol for intrauterine device insertion in nulliparous women: a randomized controlled trial.

    abstract:OBJECTIVE:To examine the effects of preprocedure misoprostol on intrauterine device (IUD) placement in nulliparous women. STUDY DESIGN:In this randomized controlled double-blind trial at the University of New Mexico reproductive health clinic, nulliparous women requesting an IUD were randomized to 400 mcg of buccal mi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2013.11.018

    authors: Espey E,Singh RH,Leeman L,Ogburn T,Fowler K,Greene H

    更新日期:2014-03-01 00:00:00

  • Fetal membranes act as a barrier for adenoviruses: gene transfer into exocoelomic cavity of rat fetuses does not affect cells in the fetus.

    abstract:OBJECTIVES:In utero gene therapy has a potential to correct genetic disorders before the first clinical symptoms appear. Our aim was to examine whether the exocoelomic cavity between amniotic and chorionic membranes offers a minimally invasive route for gene transfer to the fetus during early pregnancy. STUDY DESIGN:W...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2003.07.010

    authors: Laurema A,Vanamo K,Heikkilä A,Riekkinen M,Heinonen S,Ylä-Herttuala S

    更新日期:2004-01-01 00:00:00

  • The role of Chlamydia trachomatis in Bartholin's gland abscess.

    abstract::Chlamydia trachomatis is becoming increasingly known for its ability to cause severe injury to the female genital tract. Little investigation has been done in its role in diseases of Bartholin's glands. We present what we believe to be the first case report of an abscess of a Bartholin's gland in which Chlamydia trach...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Saul HM,Grossman MB

    更新日期:1988-03-01 00:00:00

  • Rectal misoprostol versus intravenous oxytocin for the prevention of postpartum hemorrhage after vaginal delivery.

    abstract:OBJECTIVE:To compare rectally administered misoprostol to intravenously administered oxytocin for the management of third-stage labor. STUDY DESIGN:Subjects were randomized to receive two, 200-microg misoprostol tablets rectally (study medication) plus 2 mL saline in Ringer's lactate intravenously or two lactose table...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mob.2001.117360

    authors: Gerstenfeld TS,Wing DA

    更新日期:2001-10-01 00:00:00

  • In vitro induction of prolactin production and aromatase activity by gonadal steroids exclusively in the stroma of separated proliferative human endometrium.

    abstract::Prolactin production by decidualized human endometrium has been demonstrated in organ explant cultures and presumed to be of stromal origin by immunocytochemistry and the presence of simultaneous stromal histologic changes. To test the hypothesis that endometrial prolactin production is exclusively of stromal origin, ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)91325-7

    authors: Randolph JF Jr,Peegel H,Ansbacher R,Menon KM

    更新日期:1990-04-01 00:00:00

  • Sonographic evaluation of the cervix during ovulation induction.

    abstract::With the induction of ovulation, clomiphene citrate and human menopausal gonadotropin have the potential to stimulate the endocervical glands. We have found that the degree of mucus production can occasionally be quite large and hence is detectable by sonographic evaluation as an anechoic cervical mass. The incidence ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80287-9

    authors: Hill LM,Coulam CB,Kislak SL,Peterson CS,Runco CJ

    更新日期:1987-11-01 00:00:00

  • Agricultural-related chemical exposures, season of conception, and risk of gastroschisis in Washington State.

    abstract:OBJECTIVE:We sought to determine if periconceptional exposure to agrichemicals was associated with the development of gastroschisis. STUDY DESIGN:We conducted a retrospective, case-controlled study using Washington State Birth Certificate and US Geological Survey databases. Cases included all live-born singleton infan...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2010.01.023

    authors: Waller SA,Paul K,Peterson SE,Hitti JE

    更新日期:2010-03-01 00:00:00

  • Intrauterine ultrasonographic assessments of embryonic development.

    abstract:OBJECTIVE:Our purpose was to describe embryonal anatomic structures by use of intrauterine ultrasonography with a 20 MHz flexible catheter-based, high-resolution, real-time miniature transducer. STUDY DESIGN:Thirty-four women about to undergo therapeutic abortion from 7 to 9.9 weeks' gestation were studied with specia...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(95)90425-5

    authors: Fujiwaki R,Hata T,Hata K,Kitao M

    更新日期:1995-12-01 00:00:00

  • Serial noninvasive evaluation of cardiovascular hemodynamics during pregnancy.

    abstract::M-mode echocardiography, in combination with electrocardiography and phonocardiography, has been used to measure pulmonary capillary pressure as well as other cardiac functions. Serial hemodynamic evaluations by use of this technique were performed in seven healthy pregnant women in the recumbent position. Each patien...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90146-3

    authors: Mashini IS,Albazzaz SJ,Fadel HE,Abdulla AM,Hadi HA,Harp R,Devoe LD

    更新日期:1987-05-01 00:00:00

  • Lycopene and other carotenoid intake in relation to risk of uterine leiomyomata.

    abstract:OBJECTIVE:Carotenoids have antioxidant properties and have been associated with reduced risks of some cancers. We hypothesized that carotenoid intake may reduce the risk of diagnosed uterine leiomyoma (UL). STUDY DESIGN:We evaluated the associations between dietary carotenoids and risk of diagnosed UL in 82,512 premen...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2007.05.033

    authors: Terry KL,Missmer SA,Hankinson SE,Willett WC,De Vivo I

    更新日期:2008-01-01 00:00:00

  • Candida albicans: cellular immune system interactions during different stages of the menstrual cycle.

    abstract::Candidal vaginitis most often recurs during pregnancy and in the late luteal phase just before menstruation. We examined the influence of the stage of the menstrual cycle on the cellular immune response to Candida albicans, the efficiency of C. albicans germination in sera, and the ability of products from activated l...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(89)90649-2

    authors: Kalo-Klein A,Witkin SS

    更新日期:1989-11-01 00:00:00

  • Relationship of maternal amino acids and proteins to fetal growth and mental development.

    abstract::The relationship of maternal amino acids, proteins, and certain other factors to fetal development (weight and cranial volume at birth and mental and motor scores at 8 months of age) was investigated in 129 gravidas. Maternal prepregnancy weight was significantly related to birth weight and cranial volume in the newbo...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)33441-x

    authors: Moghissi KS,Churchill JA,Kurrie D

    更新日期:1975-10-15 00:00:00

  • Cocaine alters placental production of thromboxane and prostacyclin.

    abstract:OBJECTIVE:The objective of this study was to test the hypothesis that cocaine alters placental prostaglandin production in vitro. STUDY DESIGN:Placentas were obtained from healthy women (n = 6) after normal vaginal delivery at term. Placental explants (300 mg) were incubated in duplicate at 37 degrees C in the presenc...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(94)90015-9

    authors: Monga M,Chmielowiec S,Andres RL,Troyer LR,Parisi VM

    更新日期:1994-10-01 00:00:00

  • Effect of laxatives on gastrointestinal functional recovery in fast-track hysterectomy: a double-blind, placebo-controlled randomized study.

    abstract:OBJECTIVE:The purpose of this study was to determine the effect of early oral bowel stimulation with osmotic laxatives on gastrointestinal function, postoperative nausea and vomiting (PONV) and pain in patients who undergo fast-track abdominal hysterectomy. STUDY DESIGN:This was a double-blind, placebo-controlled stud...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2006.10.902

    authors: Hansen CT,Sørensen M,Møller C,Ottesen B,Kehlet H

    更新日期:2007-04-01 00:00:00

  • Postpartum dexamethasone for women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome: a double-blind, placebo-controlled, randomized clinical trial.

    abstract:OBJECTIVE:The purpose of this study was to determine the effectiveness of postpartum dexamethasone in patients with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. STUDY DESIGN:A prospective, randomized, double-blind trial was conducted in which 105 women with HELLP syndrome were enrolled and as...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ajog.2007.10.797

    authors: Katz L,de Amorim MM,Figueiroa JN,Pinto e Silva JL

    更新日期:2008-03-01 00:00:00

  • Elevated serum ferritin in the altered ferrokinetics of toxemia of pregnancy.

    abstract::The serum concentration of ferritin in 11 patients with toxemia of pregnancy was compared to that of normal women in the early third trimester of pregnancy and in labor at term. The mean concentration of ferritin for toxemic patients was 91.8 ng/ml compared to 18.4 ng/ml and 19.4 ng/ml for the two control groups, resp...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90247-2

    authors: Entman SS,Richardson LD,Killam AP

    更新日期:1982-10-15 00:00:00

  • Conservative treatment of ectopic pregnancy with methotrexate.

    abstract::Six subjects with distal ampullary ectopic pregnancies were treated with four doses of intravenous methotrexate (1.0 mg/kg) followed by four doses of leucovorin (0.1 mg/kg, intramuscularly). The diagnosis was established in all cases by laparoscopy following sonography and radioimmunoassay for serum beta subunit of hu...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(86)90716-7

    authors: Ory SJ,Villanueva AL,Sand PK,Tamura RK

    更新日期:1986-06-01 00:00:00

  • Variations in red blood cell proton T1 relaxation times that correspond to menstrual cycle changes.

    abstract::A study was made of the relationship of proton T1 relaxation times and stage of the menstrual cycle. Preliminary data show that these indicators of red blood cell hydration status may be useful as objective markers of premenstrual tension. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(85)90358-8

    authors: Rosenthal JS,Strauss A,Minkoff LA,Winston A

    更新日期:1985-12-01 00:00:00

  • Women and smoking: an update for the 1990s.

    abstract::Cigarette smoking is associated with many health hazards, ranging from lung cancer to low infant birth weight. In the United States in 1994, 23.1% of all women and 14.6% of pregnant women smoked. Few physicians ask their patients about smoking, although minimal effort by physicians could help many smokers to quit. Thi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1053/ob.1996.v175.a74919

    authors: Kendrick JS,Merritt RK

    更新日期:1996-09-01 00:00:00

  • Epidermal growth factor receptor expression in normal ovarian epithelium and ovarian cancer. I. Correlation of receptor expression with prognostic factors in patients with ovarian cancer.

    abstract::Previous studies in breast and bladder cancer have suggested that epidermal growth factor receptor is expressed by only a proportion of cancers and is associated with poor clinical outcome. We used a monoclonal antibody specifically reactive with the extracellular domain of the epidermal growth factor receptor to loca...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)80044-x

    authors: Berchuck A,Rodriguez GC,Kamel A,Dodge RK,Soper JT,Clarke-Pearson DL,Bast RC Jr

    更新日期:1991-02-01 00:00:00

  • Antibiotic treatment of preterm labor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial.

    abstract:OBJECTIVE:Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration to women in preterm labor with intact membranes. We attempted to determine the effect of ampicillin-amoxicillin and erythr...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/0002-9378(93)90003-2

    authors: Romero R,Sibai B,Caritis S,Paul R,Depp R,Rosen M,Klebanoff M,Sabo V,Evans J,Thom E

    更新日期:1993-10-01 00:00:00