The effect of the prostaglandin F compounds on the contractility of the pregnant human uterus.

Abstract:

:The aim of this paper was to study the influence of prostaglandins compounds on the pregnant human uterus in situ. Recordings of uterine motility were made on 14 pregnant women by measuring the amniotic pressure. PGE1 alpha and PGF2 alpha were administered intravenously as single injections. It was found that PGF2 alpha and, to a minor extent, PGE1 alpha had a stimulating effect characterized by an increment of tone. The threshold dose to induce contractility was 8 times greater for PGF2 alpha than it was for PGE1.

journal_name

Am J Obstet Gynecol

authors

Bygdeman M,Kwon SU,Mukherjee T,Roth-Brandel U,Wiqvist N

doi

10.1016/0002-9378(70)90042-6

subject

Has Abstract

pub_date

1970-02-15 00:00:00

pages

567-72

issue

4

eissn

0002-9378

issn

1097-6868

pii

0002-9378(70)90042-6

journal_volume

106

pub_type

杂志文章
  • Suppression of lymphocyte reactivity in vitro by supernatants of explants of human endometrium.

    abstract::To clarify the possible immunologic functions of the endometrium before implantation, supernatants from explant cultures of human endometrial tissues were examined for effects on mixed lymphocyte reaction and phytohemagglutinin M-stimulated cultures. Supernatants obtained from both proliferative and secretory phase en...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80095-9

    authors: Wang HS,Kanzaki H,Yoshida M,Sato S,Tokushige M,Mori T

    更新日期:1987-10-01 00:00:00

  • Modern indications for cesarean section.

    abstract::Total cesarean section rates and rates of various indications for primary cesarean section were reviewed for four yearly periods during the past decade. The time periods studied were chosen to follow the introduction of new obstetric practices and technologic advances in monitoring fetal condition. The total cesarean ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(79)90426-5

    authors: Mann LI,Gallant J

    更新日期:1979-10-15 00:00:00

  • Adrenomedullin concentrations in umbilical cord plasma of uncomplicated term pregnancies.

    abstract:OBJECTIVE:The study's objective was to determine whether there is a difference in the plasma concentration of adrenomedullin, a hypotensive peptide, between arterial and venous umbilical cord blood of uncomplicated gestations with vaginal delivery. STUDY DESIGN:Arterial and venous umbilical cord blood was obtained imm...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(98)70217-0

    authors: Hoeldtke NJ,Wagner RK,Moore KH,Calhoun BC,Hume RF Jr

    更新日期:1998-10-01 00:00:00

  • Shift work, duration of pregnancy, and birth weight: the National Birth Cohort in Denmark.

    abstract:OBJECTIVE:We used the Danish National Birth Cohort to estimate the effect of shift work on the duration of pregnancy and birth weight. STUDY DESIGN:In the Danish National Birth Cohort (1998-2001), we identified women (and their singleton births): 32465 women with daytime work, 1038 women with fixed evening work, 400 w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2003.12.002

    authors: Zhu JL,Hjollund NH,Olsen J,National Birth Cohort in Denmark.

    更新日期:2004-07-01 00:00:00

  • Which factors affect the occurrence of severe cerebral lesions in preterm neonates who are born with intrauterine infection?

    abstract:OBJECTIVE:The purpose of this study was to evaluate which factors affect the occurrence of neonatal ultrasonographic evidence of severe cerebral lesions in the presence of intrauterine infection. STUDY DESIGN:From a cohort of 567 singleton neonates who were born between 24.0 and 31.6 weeks of gestation, we identified ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2008.06.059

    authors: Locatelli A,Ghidini A,Assi F,Andreani M,Malguzzi S,Paterlini G

    更新日期:2008-10-01 00:00:00

  • Gonococcicidal action of capper in vitro.

    abstract::Several copper and cupric ion sources were shown to kill or inhibit the growth of Neisseria gonorrhoeae in vitro. The media used was GC Agar Base supplemented with Isovitalex. Pure copper shot, cupric sulfate, and cupric chloride were used as copper sources. E. coli and Neisseria meningitis were used in addition to...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(73)90889-2

    authors: Fiscina B,Oster GK,Oster G,Swanson J

    更新日期:1973-05-01 00:00:00

  • Are risk factors the same for small for gestational age versus other preterm births?

    abstract:OBJECTIVES:This article explores whether the impact of social and demographic risk factors for preterm birth differs for small for gestational age preterm births versus other preterm births. STUDY DESIGN:This was a European case control study of the determinants of preterm birth (4700 cases and 6460 controls). Small f...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2001.114869

    authors: Zeitlin JA,Ancel PY,Saurel-Cubizolles MJ,Papiernik E

    更新日期:2001-07-01 00:00:00

  • Reduced uterine blood flow and fetal hypoxemia with acute maternal stress: experimental observation in the pregnant baboon.

    abstract::The effects of maternal hyperexcitability on the fetus were studied in 17 baboons. In the period of agitation, induced by stressful stimulus such as exposure to bright light or by clamping of the toe, the mother exhibited an increase in arterial blood pressure and, in some instances, arrhythmia. These changes were acc...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(16)33032-0

    authors: Morishima HO,Yeh MN,James LS

    更新日期:1979-06-01 00:00:00

  • The association of cerebral palsy and death with small-for-gestational-age birthweight in preterm neonates by individualized and population-based percentiles.

    abstract:OBJECTIVE:The objective of the study was to determine whether an individualized growth standard (IS) improves the identification of preterm small-for-gestational-age (SGA) neonates at risk of developing moderate/severe cerebral palsy (CP) or death. STUDY DESIGN:This study was a secondary analysis of data from a random...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2013.06.007

    authors: Grobman WA,Lai Y,Rouse DJ,Spong CY,Varner MW,Mercer BM,Leveno KJ,Iams JD,Wapner RJ,Sorokin Y,Thorp JM Jr,Ramin SM,Malone FD,O'Sullivan MJ,Hankins GD,Caritis SN,Eunice Kennedy Shriver National Institute of Child Health and

    更新日期:2013-10-01 00:00:00

  • Placental mesenchymal dysplasia.

    abstract::Placental mesenchymal dysplasia is a benign condition that can be confused with a molar pregnancy by ultrasound scanning and gross examination. Conservative management should be considered with a normal-appearing singleton fetus and a cystic-appearing placenta. We present a case of placental mesenchymal dysplasia with...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2011.08.019

    authors: Woo GW,Rocha FG,Gaspar-Oishi M,Bartholomew ML,Thompson KS

    更新日期:2011-12-01 00:00:00

  • Hysteroscopic findings after unsuccessful dilatation and curettage for abnormal uterine bleeding.

    abstract::In recent years numerous articles have reported on the inaccuracies of the dilatation and curettage procedure, citing a false-negative rate of up to 10% to 15%. Indeed, several articles have reported that, in this era of simplified endoscopy, the blind dilatation and curettage should no longer play a significant role ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90367-5

    authors: Brooks PG,Serden SP

    更新日期:1988-06-01 00:00:00

  • Cluster analysis of spontaneous preterm birth phenotypes identifies potential associations among preterm birth mechanisms.

    abstract:OBJECTIVE:We sought to use an innovative tool that is based on common biologic pathways to identify specific phenotypes among women with spontaneous preterm birth (SPTB) to enhance investigators' ability to identify and to highlight common mechanisms and underlying genetic factors that are responsible for SPTB. STUDY ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ajog.2015.06.011

    authors: Esplin MS,Manuck TA,Varner MW,Christensen B,Biggio J,Bukowski R,Parry S,Zhang H,Huang H,Andrews W,Saade G,Sadovsky Y,Reddy UM,Ilekis J

    更新日期:2015-09-01 00:00:00

  • Incorporating endovaginal ultrasonography into the overall gynecologic examination.

    abstract::Previously endovaginal ultrasonography was considered an adjunct for use in full-service ultrasound facilities by subspecialists only. The technique, however, has tremendous application for use by the clinician in the examination room for patients at bimanual examination. This is because the procedure is meant to be p...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90971-9

    authors: Goldstein SR

    更新日期:1990-03-01 00:00:00

  • Cadmium levels in maternal blood, fetal cord blood, and placental tissues of pregnant women who smoke.

    abstract::Previous studies have reported that cigarette smoking is a major source of exposure to cadmium (Cd). This study was carried out to determine the degree of exposure to Cd of pregnant women who smoke and to determine the degree of exposure to Cd of pregnant women who smoke and to determine the disposition of the Cd in t...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(82)90786-4

    authors: Kuhnert PM,Kuhnert BR,Bottoms SF,Erhard P

    更新日期:1982-04-15 00:00:00

  • A prospective study on the lack of development of antisperm antibodies in women undergoing intrauterine insemination.

    abstract::To test the hypothesis that intrauterine insemination with washed spermatozoa induces antisperm antibody formation, we measured serum antisperm antibody levels by the Immunobead technique in a population of women receiving exogenous gonadotropins. Antibody levels were measured before therapy (baseline) and then serial...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(89)80045-6

    authors: Horvath PM,Beck M,Bohrer MK,Shelden RM,Kemmann E

    更新日期:1989-03-01 00:00:00

  • Increasing NIH funding for academic departments of obstetrics and gynecology: a call to action.

    abstract::The National Institutes of Health funding for reproductive sciences research, specifically in academic departments of obstetrics and gynecology, is disproportionately low. Research is one of the most important pillars in advancing healthcare. Despite US Congress' vision in providing increased funding to the National I...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2020.03.022

    authors: Rice LW,Cedars MI,Sadovsky Y,Siddiqui NY,Teal SB,Wright JD,Zorbas A,Del Carmen MG

    更新日期:2020-07-01 00:00:00

  • Color Doppler flow patterns and flow velocity waveforms of the intraplacental fetal circulation in growth-retarded fetuses.

    abstract:OBJECTIVE:We examined intraplacental color Doppler flow patterns and spectral Doppler flow velocity waveforms of villous arteries in pregnancies with intrauterine growth retardation. STUDY DESIGN:A total of 192 uncomplicated pregnancies and 29 pregnancies with intrauterine growth retardation between 26 and 41 weeks' g...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(94)90143-0

    authors: Rotmensch S,Liberati M,Luo JS,Kliman HJ,Gollin Y,Bellati U,Hobbins JC,Copel JA

    更新日期:1994-11-01 00:00:00

  • Inflammatory-mediated model of cerebral palsy with developmental sequelae.

    abstract:OBJECTIVE:Cerebral palsy (CP) is characterized by motor deficits. There is increasing evidence that CP may result from inflammatory and infection-mediated white matter damage. Our objective was to develop an inflammatory model for CP based on chronic lipopolysaccharide (LPS) exposure with a recognizable phenotype in of...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2005.05.072

    authors: Toso L,Poggi S,Park J,Einat H,Roberson R,Dunlap V,Woodard J,Abebe D,Spong CY

    更新日期:2005-09-01 00:00:00

  • Preeclampsia is not associated with altered platelet vasopressin binding and cytosolic Ca++ concentration.

    abstract:OBJECTIVES:Preeclampsia is an important cause of fetal and maternal morbidity and mortality. Recently it was described that platelet cytosolic Ca++ levels could be used to screen for preeclampsia. The current study investigated platelet arginine vasopressin receptor characteristics, platelet cytosolic Ca++ levels, plas...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90276-o

    authors: van der Post JA,Konijnenberg A,Boer K,Schaap MC,van Boxtel CE,Sturk A,Boer GJ,Swaab DF

    更新日期:1993-11-01 00:00:00

  • Peritoneal fluid prostaglandins and prostanoids in women with endometriosis, chronic pelvic inflammatory disease, and pelvic pain.

    abstract::Peritoneal fluid obtained at laparoscopy from 49 women was measured for its content of prostaglandin E2 (PGE2), prostaglandin F2 alpha (PGF2 alpha), 6-keto-prostaglandin F1 alpha (6-KF), and thromboxane B2 (TxB2) by specific radioimmunoassays. In normal women (n = 10), the concentrations of prostaglandins in peritonea...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(84)90713-0

    authors: Dawood MY,Khan-Dawood FS,Wilson L Jr

    更新日期:1984-02-15 00:00:00

  • Elevated plasma endothelial microparticles in preeclampsia.

    abstract:OBJECTIVE:The purpose of this study was to assess endothelial dysfunction in women with preeclampsia by measuring endothelial microparticles. STUDY DESIGN:A case-control study was conducted on 20 women with preeclampsia and 20 healthy pregnant women as control subjects. Endothelial microparticles were measured by flow...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/s0002-9378(03)00469-1

    authors: González-Quintero VH,Jiménez JJ,Jy W,Mauro LM,Hortman L,O'Sullivan MJ,Ahn Y

    更新日期:2003-08-01 00:00:00

  • Antibodies to Chlamydia trachomatis and risk for tubal pregnancy.

    abstract::We performed a case-control study of the effect of exposure to Chlamydia trachomatis on the risk for tubal pregnancy. Sixty women with tubal pregnancies and 60 matched control women with normal second-trimester intrauterine pregnancies were studied. Cases were more likely than controls to have detectable antichlamydia...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(88)80177-7

    authors: Walters MD,Eddy CA,Gibbs RS,Schachter J,Holden AE,Pauerstein CJ

    更新日期:1988-10-01 00:00:00

  • The relationship of maternal position to the results of brief nonstress tests: a randomized clinical trial.

    abstract:OBJECTIVE:This study was undertaken to determine whether maternal posture (left lateral recumbent vs semi-Fowler position) had any effect on nonstress test results when the test was performed for a shortened period (10 minutes). STUDY DESIGN:In this randomized clinical trial of 108 patients with singleton pregnancies ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mob.2000.105443

    authors: Nathan EB,Haberman S,Burgess T,Minkoff H

    更新日期:2000-05-01 00:00:00

  • Flow velocity waveforms in uterine and umbilical arteries during the angiotensin II sensitivity test.

    abstract::The angiotensin II sensitivity test has been used to predict the development of hypertension during pregnancy. We investigated the systolic/diastolic ratios of flow velocity waveforms in the uterine and umbilical arteries by means of a color Doppler system in 15 healthy women at 24 to 26 weeks' gestation. A significan...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(90)90015-y

    authors: Erkkola RU,Pirhonen JP

    更新日期:1990-05-01 00:00:00

  • Long-term survival after chemotherapy for advanced epithelial ovarian carcinoma.

    abstract::Four hundred twenty-nine patients were entered into four prospective randomized clinical studies between January 1, 1973, and July 1, 1979. The records of 395 of these were analyzed to determine the proportion of patients surviving 48 months after therapy initiation. Ninety-six patients (24%) were living at 48 months,...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0002-9378(84)90543-x

    authors: Wharton JT,Edwards CL,Rutledge FN

    更新日期:1984-04-01 00:00:00

  • Pregnancy enhances cocaine-induced stimulation of uterine contractions in the chronically instrumented rat.

    abstract:OBJECTIVE:Our purpose was to test whether cocaine stimulates uterine activity in nonpregnant and pregnant rats. STUDY DESIGN:The carotid artery and jugular vein were chronically catheterized, and a microballoon probe was inserted into the uterine cavity of 15 pregnant and 14 nonpregnant female rats. Conscious animals ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(96)70273-9

    authors: Nakahara K,Iso A,Chao CR,Cooper TB,Morishima HO

    更新日期:1996-07-01 00:00:00

  • The relationship between perineal cosmetic talc usage and ovarian talc particle burden.

    abstract:OBJECTIVE:Epidemiologic studies support the hypothesis of a dose-related risk of epithelial ovarian cancer with perineal talc usage exposure. Frequency and duration of talc has not been previously correlated with ovarian talc content. STUDY DESIGN:Ovaries were studied from 24 women undergoing incidental oophorectomy w...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(96)70597-5

    authors: Heller DS,Westhoff C,Gordon RE,Katz N

    更新日期:1996-05-01 00:00:00

  • Cigarette smoking during pregnancy in relation to placenta previa.

    abstract::To evaluate the relationship between cigarette smoking and the occurrence of placenta previa, we used interview and medical record data to conduct a case-control analysis of 69 placenta previa cases and 12,351 controls. The unadjusted relative risk estimate of placenta previa for women reported to have "ever smoked" d...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(91)90217-f

    authors: Williams MA,Mittendorf R,Lieberman E,Monson RR,Schoenbaum SC,Genest DR

    更新日期:1991-07-01 00:00:00

  • Fetal breathing movements in response to maternal inhalation of 5% carbon dioxide.

    abstract::The effect upon fetal breathing movements (FBM) in 49 women with uncomplicated pregnancies who inhaled 5% carbon dioxide in air for 15 minutes was observed with an ADR real-time ultrasound scanner. A threefold increase in FBM occurred during the inhalation of CO2. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(80)90867-4

    authors: Ritchie JW,Lakhani K

    更新日期:1980-02-01 00:00:00

  • A comparison of anticipated pain before and pain rating after the procedure in patients who undergo cystourethroscopy.

    abstract:OBJECTIVE:The purpose of this study was to compare anticipated pain before the procedure and actual pain rating after the procedure in female patients who undergo cystourethroscopy. STUDY DESIGN:Eighty-seven consecutive female patients completed a 10-cm visual analog pain scale before and after cystourethroscopy. A 24...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1067/mob.2003.377

    authors: Ellerkmann RM,Dunn JS,McBride AW,Kummer LG,Melick CF,Bent AE,Blomquist JL

    更新日期:2003-07-01 00:00:00