Suppression of lymphocyte reactivity in vitro by supernatants of explants of human endometrium.

Abstract:

:To clarify the possible immunologic functions of the endometrium before implantation, supernatants from explant cultures of human endometrial tissues were examined for effects on mixed lymphocyte reaction and phytohemagglutinin M-stimulated cultures. Supernatants obtained from both proliferative and secretory phase endometria showed significant dose-related suppressive effects; the suppressive activity of secretory phase endometria was higher than that of proliferative phase endometria. On the other hand, no inhibitory effect was identified in supernatants from similar cultures of peritoneum and omentum, while supernatants of fallopian tubes showed slight suppressive activity. These results suggest the existence of soluble nonspecific immunosuppressive factor(s) released from human endometrium (especially during the secretory phase), and imply that these factor(s) may exert an important role in protecting the fertilized ovum from maternal rejection.

journal_name

Am J Obstet Gynecol

authors

Wang HS,Kanzaki H,Yoshida M,Sato S,Tokushige M,Mori T

doi

10.1016/s0002-9378(87)80095-9

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

956-63

issue

4 Pt 1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(87)80095-9

journal_volume

157

pub_type

杂志文章
  • Elevated circulating thrombomodulin in severe preeclampsia.

    abstract::A relationship between serum thrombomodulin and preeclampsia was investigated. In women with severely preeclamptic pregnancies, serum thrombomodulin levels were found to be significantly elevated as compared with those of matched control subjects (p < 0.005). Serum thrombomodulin levels correlated positively with seru...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90151-8

    authors: Hsu CD,Iriye B,Johnson TR,Witter FR,Hong SF,Chan DW

    更新日期:1993-07-01 00:00:00

  • The effect of a progesterone-releasing intrauterine contraceptive device on uterine secretion of prostaglandin F2alpha and life-span of corpora lutea in the ewe.

    abstract::Two studies were conducted to investigate the effect of a progesterone-releasing intrauterine contraceptive device (IUD) on uterine secretion of prostaglandin (PG) F2alpha associated with IUD-induced luteolysis in sheep. In bilaterally ovulating ewes receiving an IUD on day 3 (estrus = day 0) intrauterine release of p...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90803-7

    authors: Murdoch WJ,Lewis GS,Inskeep EK,Tillson SA

    更新日期:1978-09-01 00:00:00

  • The maternal health clinic: an initiative for cardiovascular risk identification in women with pregnancy-related complications.

    abstract:OBJECTIVE:Women who develop certain common pregnancy complications have a greater chance of developing cardiovascular disease (CVD) later in life. However, most health care providers do not provide postpartum cardiovascular risk counselling or follow-up. The Maternal Health Clinic was established to address this gap in...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2013.12.001

    authors: Cusimano MC,Pudwell J,Roddy M,Cho CK,Smith GN

    更新日期:2014-05-01 00:00:00

  • Pelvic girdle pain in pregnancy: the impact of parity.

    abstract:OBJECTIVE:The purpose of this study was to estimate the association of parity with pelvic girdle syndrome (PGS; pain in anterior and bilateral posterior pelvis). STUDY DESIGN:We included 75,939 pregnant women in the Norwegian Mother and Child Cohort Study. Data were obtained by self-administered questionnaires. RESUL...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2010.03.040

    authors: Bjelland EK,Eskild A,Johansen R,Eberhard-Gran M

    更新日期:2010-08-01 00:00:00

  • Endometriosis after neosalpingostomy.

    abstract::A patient seen for infertility developed severe endometriosis within 2 years of neosalpingostomy for bilateral fallopian tube obstruction. A retrospective review of infertility surgeries revealed none of 20 patients with obstructed tubes to have endometriosis, compared with 66 of 125 (52.8%) with at least one patent f...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(94)70160-1

    authors: Woodworth SH,Pridham DD,Cook CL,Sanfilippo JS,Yussman MA

    更新日期:1994-05-01 00:00:00

  • Alterations in the baroreflex occur late in pregnancy in conscious rabbits.

    abstract::Experiments were performed in conscious rabbits to investigate when during pregnancy cardiac baroreceptor reflex gain decreases. A decrease in gain was first observed after 3 weeks of gestation (-34.1 +/- 4.9 to -15.7 +/- 3.1 beats/min/mm Hg, p < 0.05) and became more pronounced after 4 weeks (-30.2 +/- 4.7 to -8.6 +/...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(97)70571-4

    authors: Quesnell RR,Brooks VL

    更新日期:1997-03-01 00:00:00

  • Significant reduction in umbilical artery metabolic acidosis after implementation of intrapartum ST waveform analysis of the fetal electrocardiogram.

    abstract:BACKGROUND:Although the evidence regarding the benefit of using ST waveform analysis of the fetal electrocardiogram is conflicting, ST waveform analysis is considered as adjunct to identify fetuses at risk for asphyxia in our center. Most randomized controlled trials and meta-analyses have not shown a significant decre...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2019.02.049

    authors: Landman AJEMC,Immink-Duijker ST,Mulder EJH,Koster MPH,Xodo S,Visser GHA,Groenendaal F,Kwee A

    更新日期:2019-07-01 00:00:00

  • Gap junction formation in human myometrium: a key to preterm labor?

    abstract:OBJECTIVE:The purpose of this study was to determine if gap junctions are a necessary component of the human laboring uterus and if their presence in myometrium is a prerequisite for both term and preterm labor. STUDY DESIGN:We obtained 27 human myometrial samples at cesarean section or nongravid hysterectomy. Gap jun...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(11)90806-0

    authors: Balducci J,Risek B,Gilula NB,Hand A,Egan JF,Vintzileos AM

    更新日期:1993-05-01 00:00:00

  • Ampicillin prophylaxis in preterm premature rupture of the membranes: a prospective randomized study.

    abstract::It is hypothesized that ampicillin may treat subclinical deciduitis and prolong the "effective" latent period in patients with preterm premature rupture of the membranes. We studied 82 patients with preterm rupture of membranes who were managed expectantly and were randomly assigned either to receive ampicillin prophy...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-9378(88)80002-4

    authors: Amon E,Lewis SV,Sibai BM,Villar MA,Arheart KL

    更新日期:1988-09-01 00:00:00

  • Antepartum fetal heart rate response to sound stimulation: the acoustic stimulation test.

    abstract::The fetal heart rate acceleration response to an acoustic stimulation was compared to the traditional nonstress test in regard to pregnancy outcome, as reflected by the incidence of intrapartum fetal distress, meconium staining of the amniotic fluid, 1- and 5-minute Apgar scores, and perinatal mortality. Fetuses with ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(84)80029-0

    authors: Serafini P,Lindsay MB,Nagey DA,Pupkin MJ,Tseng P,Crenshaw C Jr

    更新日期:1984-01-01 00:00:00

  • Can cervical cancer be prevented by a see, screen, and treat program? A pilot study.

    abstract:OBJECTIVE:Our purpose was to determine the feasibility of providing a cervical screening facility to the underprivileged communities through an educational program and a mobile clinic in which cytologic smears could be taken, screened immediately, and, when appropriate, the patients treated on site with minimal delay. ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(96)70327-7

    authors: Megevand E,Van Wyk W,Knight B,Bloch B

    更新日期:1996-03-01 00:00:00

  • Laparoscopic salpingostomy versus laparoscopic local methotrexate injection in the management of unruptured ectopic gestation.

    abstract:OBJECTIVE:Our goal was to determine whether laparoscopic salpingostomy is preferable to laparoscopic methotrexate injection in the management of unruptured tubal gestation. STUDY DESIGN:Forty-eight patients with unruptured tubal pregnancy were prospectively randomized to either laparoscopic salpingostomy or laparoscop...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1053/ob.1996.v175.a74249

    authors: Zilber U,Pansky M,Bukovsky I,Golan A

    更新日期:1996-09-01 00:00:00

  • A six-year experience with paravaginal defect repair for stress urinary incontinence.

    abstract::One hundred forty-nine consecutive patients who had surgery from May 1890 through December 1986 were evaluated to assess the functional and anatomic results of the paravaginal defect repair for stress urinary incontinence. All patients had their preoperative assessment, operative procedure, and postoperative follow-up...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(89)90867-3

    authors: Shull BL,Baden WF

    更新日期:1989-06-01 00:00:00

  • A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome.

    abstract:OBJECTIVE:To characterize the serum metabolome of a primate model of in utero high-fat exposure. STUDY DESIGN:Serum from maternal and fetal (e130) macaque monkeys exposed to either a high-fat or control diet were analyzed by gas chromatography-mass spectrometry. Multivariate data analysis was performed to reduce the g...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.06.041

    authors: Cox J,Williams S,Grove K,Lane RH,Aagaard-Tillery KM

    更新日期:2009-09-01 00:00:00

  • Maternal serum alpha-fetoprotein screening: further consideration of low-volume testing.

    abstract::Unrecognized assay drift that may occur during low-volume (fewer than 500 specimens per week) maternal serum alpha-fetoprotein testing could result in either underestimation or overestimation of the number of pregnant women who are at increased risk of fetal malformations and genetic anomalies. Quality control softwar...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(91)90502-i

    authors: Strickland DM,Butzin CA,Wians FH Jr

    更新日期:1991-03-01 00:00:00

  • Acute pulmonary complications of molar pregnancy.

    abstract::Of 128 patients receiving primary treatment for molar pregnancy at Women's Hospital, Los Angeles County/University of Southern California Medical Center, after uterine evacuation 12 (10.7%) developed self-limited, acute pulmonary complications characterized by tachycardia, tachypnea, and hypoxemia. Multiple contributi...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(79)90341-7

    authors: Twiggs LB,Morrow CP,Schlaerth JB

    更新日期:1979-09-15 00:00:00

  • Where to look for the sentinel lymph node in cervical cancer.

    abstract:OBJECTIVE:The aim of this study was to analyze lymphatic spread to pelvic, parametrial, and paraaortic lymph nodes in patients with cervical cancer. STUDY DESIGN:We reviewed 619 patients with invasive cervical cancer treated by radical abdominal hysterectomy and systematic pelvic or pelvic and paraaortic lymphadenecto...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2007.09.053

    authors: Bader AA,Winter R,Haas J,Tamussino KF

    更新日期:2007-12-01 00:00:00

  • 2-Chloroprocaine for local perineal infiltration.

    abstract::Lidocaine was recently found to rapidly cross the placenta and result in considerable fetal exposure after local infiltration of the perineum for episiotomy. For this reason, a more appropriate agent for local perineal infiltration might be a drug with rapid metabolism and inactive metabolites. 2-Chloroprocaine, an es...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(87)80313-7

    authors: Philipson EH,Kuhnert BR,Syracuse CD

    更新日期:1987-11-01 00:00:00

  • Evidence for estrogen synthesis in adenomyotic tissues.

    abstract:OBJECTIVE:To investigate steroidogenesis in eutopic and ectopic endometrial tissues in adenomyosis. STUDY DESIGN:Aromatase and estrone sulfatase activities were determined by anion-exchange resin column chromatography, thin-layer chromatography, and cocrystallization. The effects of danazol on the activity of these en...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90654-2

    authors: Yamamoto T,Noguchi T,Tamura T,Kitawaki J,Okada H

    更新日期:1993-09-01 00:00:00

  • The role of maternal age in twin pregnancy outcomes.

    abstract:BACKGROUND:There are limited data on how maternal age is related to twin pregnancy outcomes. OBJECTIVE:The purpose of this study was to assess the relationship between maternal age and risk for preterm birth, fetal death, and neonatal death in the setting of twin pregnancy. STUDY DESIGN:This population-based study of...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2017.03.002

    authors: McLennan AS,Gyamfi-Bannerman C,Ananth CV,Wright JD,Siddiq Z,D'Alton ME,Friedman AM

    更新日期:2017-07-01 00:00:00

  • Long-term neurodevelopmental outcome after fetal arrhythmia.

    abstract:OBJECTIVE:The purpose of this study was to determine the long-term neurodevelopmental outcome in fetuses with severe tachy- or bradyarrhythmia. STUDY DESIGN:This was a follow-up study to assess the neurologic, mental, and psychomotor development in cases with fetal cardiac arrhythmia. RESULTS:A total of 44 fetuses we...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2009.02.002

    authors: Lopriore E,Aziz MI,Nagel HT,Blom NA,Rozendaal L,Kanhai HH,Vandenbussche FP

    更新日期:2009-07-01 00:00:00

  • Induction of labor with oral prostaglandin E2 in normal and high-risk pregnancies.

    abstract::There were 153 oral prostaglandin (PG) E2 inductions attempted in 149 patients. For various reasons nine cases were dropped from the study. Of the remaining 144 induction attempts, 96 were judged successful, with a success rate of 67 per cent. Details of these inductions are presented, including summaries of three pat...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(78)90857-8

    authors: Nelson GH,Bryans CI Jr

    更新日期:1978-11-15 00:00:00

  • Evolving concepts in the mechanism of steroid action: current developments.

    abstract::The mechanisms of steroid action remain a poorly understood enigma. Although much effort has focused on the steroid receptor as a mediator of the steroid's effect in the cell, we are only beginning to understand the structure of steroid receptors. Development of monoclonal antibodies directed against both the steroid-...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(87)90015-9

    authors: Faber LE,Wakim NG,Duhring JL

    更新日期:1987-06-01 00:00:00

  • Endometrial resection versus vaginal hysterectomy for menorrhagia: long-term clinical and quality-of-life outcomes.

    abstract:OBJECTIVE:Our purpose was to compare patients' satisfaction with the effect of treatment, health-related quality of life, psychologic status, and sexual functioning 2 years after endometrial resection or vaginal hysterectomy for menorrhagia. STUDY DESIGN:Menorrhagic women < or = 50 years old with a mobile uterus small...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0002-9378(97)70445-9

    authors: Crosignani PG,Vercellini P,Apolone G,De Giorgi O,Cortesi I,Meschia M

    更新日期:1997-07-01 00:00:00

  • The influence of ovarian denervation and nerve stimulation on ovarian contractions.

    abstract::Two techniques were used to study the neuromuscular control of rabbit ovarian contractions. First, the ovary was denervated by stripping its artery. Spontaneous contractions were noted, as was a normal response to exogenously administered adrenergic agents. Second, the ovarian nerves were electrically stimulated in an...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(77)90679-2

    authors: Weiner S,Wright KH,Wallach EE

    更新日期:1977-05-15 00:00:00

  • Comparison of tests for diagnosis of iron depletion in pregnancy.

    abstract::The serum ferritin level was used to diagnose iron depletion in 137 pregnant patients who came to an inner-city hospital outpatient clinic. Seventy-three patients (53.3%) had ferritin levels less than 20 micrograms/L, indicating iron depletion. The prevalence of iron depletion was 29% in the first trimester, 64% in th...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(88)90429-2

    authors: Thompson WG

    更新日期:1988-11-01 00:00:00

  • Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal Cohort.

    abstract:OBJECTIVE:The objective of the study was to investigate whether performing an amniocentesis increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 (MTCT). STUDY DESIGN:We studied HIV -1 infected mothers and their children enrolled in the multicenter French Perinatal HIV Cohort from 1985 to 2006...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2008.08.049

    authors: Mandelbrot L,Jasseron C,Ekoukou D,Batallan A,Bongain A,Pannier E,Blanche S,Tubiana R,Rouzioux C,Warszawski J,ANRS French Perinatal Cohort (EPF).

    更新日期:2009-02-01 00:00:00

  • Detection of genes that are differentially expressed during mouse embryogenesis by genetic trapping strategies.

    abstract:OBJECTIVE:Our objective was to identify novel genes that are expressed in temporally and spatially restricted patterns during mouse embryonic development and organogenesis. STUDY DESIGN:Two genetic trapping reporter constructs that lack transcriptional regulatory sequences were introduced independently into transcript...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0002-9378(93)90643-w

    authors: Johnson MD,Mahon KA

    更新日期:1993-09-01 00:00:00

  • The association between maternal antioxidant levels in midpregnancy and preeclampsia.

    abstract:OBJECTIVE:We sought to determine whether midpregnancy antioxidant levels are associated with preeclampsia, overall and by timing of onset. STUDY DESIGN:We carried out a case-control study, nested within a cohort of 5337 pregnant women in Montreal, Quebec, Canada. Blood samples obtained at 24-26 weeks were assayed for ...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/j.ajog.2015.07.027

    authors: Cohen JM,Kramer MS,Platt RW,Basso O,Evans RW,Kahn SR

    更新日期:2015-11-01 00:00:00

  • Triplet pregnancy after low-dose pulsatile gonadotropin-releasing hormone in polycystic ovarian disease.

    abstract::In a patient with polycystic ovarian disease, low-dose intravenous pulsatile gonadotropin-releasing hormone (5 mcg every hour) and no exogenous human chorionic gonadotropin induced multiple follicular development and elevated estrogen levels and resulted in a triplet pregnancy. Patients with polycystic ovarian disease...

    journal_title:American journal of obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0002-9378(86)80017-5

    authors: Filicori M,Michelacci L,Ferrari P,Campaniello E,Pareschi A,Flamigni C

    更新日期:1986-10-01 00:00:00