Immunoprotection in spontaneous remission of type 1 diabetes: long-term follow-up results.

abstract：:The insulin sensitivity of intermediary metabolism was studied in 8 non-obese men with well-controlled diet-treated non-insulin dependent diabetes (NIDDM) using a low dose incremental insulin infusion (basal, 0.005 and 0.01 U/kg h-1). Results were compared to 8 healthy male control subjects matched (NIDDM vs. controls...

journal_title：Diabetes research and clinical practice

authors： Singh BM,Krentz AJ,Nattrass M

更新日期：1993-04-01 00:00:00

abstract：AIMS:To determine the longitudinal association of the loss-of-function (LOF) PCSK9 variants (C679X and A443T), proxies of PCSK9 inhibitor drugs, with LDL-C, fasting glucose and glycated hemoglobin. METHODS:We conducted a five year, longitudinal study, nested within the Prospective Urban and Rural Epidemiology study, a...

journal_title：Diabetes research and clinical practice

authors： Chikowore T,Cockeran M,Conradie KR,van Zyl T

更新日期：2018-10-01 00:00:00

abstract：AIMS/HYPOTHESIS:The UK Prospective Diabetes Study (UKPDS) showed that biguanide therapy in overweight patients reduced the risk for any diabetes-related endpoint and all-cause mortality. Biguanides lower the blood glucose values without stimulation of insulin release. We have investigated the short-term effect of bufor...

journal_title：Diabetes research and clinical practice

authors： Ohara S,Komatsu R,Matsuyama T

更新日期：2004-11-01 00:00:00

abstract：:To elucidate the relationship between carnitine metabolism and plasma ketone body concentrations in moderately obese patients with mild glucose intolerance, the ketone body and carnitine levels in the basal state were determined in 72 obese patients: 20 with normal glucose tolerance (NGT), 29 with impaired glucose tol...

journal_title：Diabetes research and clinical practice

authors： Inokuchi T,Imamura K,Nomura K,Nomoto K,Isogai S

更新日期：1995-10-01 00:00:00

abstract：AIM:Early interventions in prediabetes can prevent or delay the incidence of type 2 diabetes mellitus (T2DM). The aim of this review was to assess the efficacy and safety of traditional Chinese patent medicine (TCPM) on the prevention of T2DM. METHODS:Seven electronic databases were searched to identify eligible trial...

journal_title：Diabetes research and clinical practice

authors： Pang B,Lian FM,Zhao XY,Zhao XM,Jin,Lin YQ,Zheng YJ,Ni Q,Tong XL

更新日期：2017-09-01 00:00:00

abstract：:We examined cross-sectional associations of sex hormone binding globulin (SHBG) with glucose among women recent GDM (n=55). SHBG was associated with fasting glucose levels before and after adjustment for covariates (p=0.015), but not with 2-h glucose. We conclude SHBG should be explored in prospective studies in GDM w...

journal_title：Diabetes research and clinical practice

authors： Kim C,Sen A,Osborne E,Lee JM,Richardson CR

更新日期：2011-09-01 00:00:00

abstract：:Insulin resistance is a hallmark of type 2 diabetes and obesity while the mechanism remains unclear. Current therapy to treat type 2 diabetes is metformin, the 5'-monophosphate-activated protein kinase (AMPK) activator, owing to the ability to augment peripheral glucose uptake. However, metformin also displays limitat...

journal_title：Diabetes research and clinical practice

authors： Zhang Z,Liu H,Liu J

更新日期：2019-10-01 00:00:00

abstract：:Despite numerous publications according to which insulin promotes atherosclerosis, there are many observations in the last fifteen years suggesting that insulin has antiatherogenic properties. Insulin has vasodilatory, antithrombotic and anti-inflammatory effects. A good glycemic control contributes to the maximum eff...

journal_title：Diabetes research and clinical practice

authors： Karamitsos DT

更新日期：2011-08-01 00:00:00

abstract：:Activity of the lower leg muscles in response to an unexpected disturbance to upright standing was studied in diabetic patients and non-diabetic matched controls. The diabetic individuals were classified into two groups: diabetic patients with normal cutaneous sensitivity in the foot (n=27) and patients with cutaneous...

journal_title：Diabetes research and clinical practice

authors： Simmons RW,Richardson C

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Islet autoimmunity, age at onset and time to insulin treatment are often used to define subgroups of diabetes. However, the latter criterion is not clinical useful. Here, we examined whether an unbiased stratification of diabetes according to age at onset, fasting C-peptide and GAD autoantibodies (GADab) defi...

journal_title：Diabetes research and clinical practice

authors： Wod M,Yderstræde KB,Halekoh U,Beck-Nielsen H,Højlund K

更新日期：2017-12-01 00:00:00

abstract：:Oral health information was included in 89.5% of diabetes education programs in states with high diabetes prevalence compared to 85.9% in low prevalence states (P = 0.22). Comparing the high to low diabetes prevalence states, there were significant differences in odds for responding "yes" to the topics "show patients ...

journal_title：Diabetes research and clinical practice

authors： Yuen HK,Marlow NM,Mahoney S,Slate E,Jenkins C,London S

更新日期：2010-12-01 00:00:00

abstract：AIMS:To evaluate the Hypoglycaemia Symptom Rating Questionnaire (HypoSRQ©) and relationships between self-reported hypoglycaemia and hypoglycaemia measured using blinded continuous glucose monitoring (CGM). METHODS:Diabetes outpatients (n = 113) recruited from Ashford and St. Peter's Hospital completed the HypoSRQ (re...

journal_title：Diabetes research and clinical practice

authors： Taylor MD,Han TS,Ward H,Bradley C

更新日期：2019-05-01 00:00:00

abstract：AIMS:Gestational diabetes mellitus (GDM) is associated with adverse obstetrical outcomes and postpartum pre-diabetes/diabetes. As the American Diabetes Association (ADA) criteria for GDM may capture obstetrical risk better than the National Diabetes Data Group (NDDG) criteria, we compared these criteria in their detect...

journal_title：Diabetes research and clinical practice

authors： Retnakaran R,Qi Y,Sermer M,Connelly PW,Zinman B,Hanley AJ

更新日期：2009-07-01 00:00:00

abstract：:Serum paraoxonase (PON) is a high-density lipoprotein-bound enzyme that can prevent oxidation of low-density lipoprotein by hydrolyzing lipid peroxides and thus exert an anti-atherogenic effect. Recent studies have suggested that glutamine(Q isoform)/arginine(R isoform) polymorphism at position 192 of PON(1) gene is a...

journal_title：Diabetes research and clinical practice

authors： Hu Y,Tian H,Liu R

更新日期：2003-07-01 00:00:00

abstract：AIMS:To assess the effects of diabetes mellitus (DM) on myocardial collagen accumulation, myocardial relaxation, and prognosis in patients with dilated cardiomyopathy (DCM). METHODS:A total of 102 consecutive DCM patients with a New York Heart Association functional class of I or II were enrolled. Patients were alloca...

journal_title：Diabetes research and clinical practice

authors： Sakakibara M,Hirashiki A,Cheng XW,Bando Y,Ohshima K,Okumura T,Funahashi H,Ohshima S,Murohara T

更新日期：2011-06-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) has been identified as a novel metabolic regulator. This cross-sectional study was performed to clarify how serum FGF21 levels were associated with clinical parameters in Japanese subjects with type 2 diabetes (n=139). Anthropometric and blood biochemical parameters, uses of drugs f...

journal_title：Diabetes research and clinical practice

authors： Eto K,Tumenbayar B,Nagashima S,Tazoe F,Miyamoto M,Takahashi M,Ando A,Okada K,Yagyu H,Ishibashi S

更新日期：2010-07-01 00:00:00

abstract：:We retrospectively examined the frequency of bladder cancer in Japanese patients with type 2 diabetes in relation to use of pioglitazone. Among a total of 663 patients identified to be taking pioglitazone, 9 had bladder cancer (1.36%). Overall the hazard ratio of 1.75 [95% CI: 0.89-3.45] for pioglitazone for bladder c...

journal_title：Diabetes research and clinical practice

authors： Fujimoto K,Hamamoto Y,Honjo S,Kawasaki Y,Mori K,Tatsuoka H,Matsuoka A,Wada Y,Ikeda H,Fujikawa J,Koshiyama H

更新日期：2013-02-01 00:00:00

abstract：AIM:We aimed at evaluating the safety of fasting Ramadan for insulin treated type 2 diabetes patients by assessing the biochemical, biometric parameters, flash glucose monitoring (FGM) data as compared to pre-Ramadan and hospital admissions with diabetes or non-diabetes conditions. The risks of fasting between those tr...

journal_title：Diabetes research and clinical practice

authors： Bashier AMK,Hussain AKB,Alawadi F,Alsayyah F,Alsaeed M,Rashid F,Abdelgadir E,Bachet F,Abuelkheir S,Elsayed M,Hassanein M

更新日期：2019-04-01 00:00:00

abstract：:Insulin administration causes various types of immune response to insulin. However, there have been no reports that insulin administration triggers pancreatic beta-cell destruction in diabetic patients. We evaluated three patients who had suffered from type 2 diabetes or impaired glucose tolerance for 5-30 years. Afte...

journal_title：Diabetes research and clinical practice

authors： Nakamura M,Nishida W,Yamada Y,Chujo D,Watanabe Y,Imagawa A,Hanafusa T,Kawasaki E,Onuma H,Osawa H,Makino H

更新日期：2008-02-01 00:00:00

abstract：:There are scant data from African populations on the association between beta-cell function and response to treatment with oral hypoglycaemic agents in Type 2 diabetes mellitus (T2DM). Fasting plasma C-peptide (FCP) and glucagon-stimulated C-peptide (GSCP) levels were measured in 116 Nigerians with T2DM at a universit...

journal_title：Diabetes research and clinical practice

authors： Oli JM,Adeyemo AA,Okafor GO,Ofoegbu EN,Onyenekwe B,Chukwuka CJ,Chen G,Chen Y,Doumatey AP,Aje TO,Rotimi CN

更新日期：2005-08-01 00:00:00

abstract：AIMS:This meta-analysis was conducted to investigate the fracture risk among patients with T2DM treated with sulfonylurea. METHODS:The PubMed and other databases were searched for eligible studies. Both randomized controlled trials and observational studies that compared the fracture risk of sulfonylurea to other hypo...

journal_title：Diabetes research and clinical practice

authors： Zhang Z,Cao Y,Tao Y,E M,Tang J,Liu Y,Li F

更新日期：2020-01-01 00:00:00

abstract：AIMS:Non-diabetic renal diseases (NDRDs) are associated with better renal outcomes than diabetic nephropathy (DN). This study was conducted to determine the common clinical markers predicting NDRDs in type 2 diabetes patients. METHODS:Patients with type 2 diabetes mellitus who underwent a renal biopsy were screened. E...

journal_title：Diabetes research and clinical practice

authors： Dong Z,Wang Y,Qiu Q,Zhang X,Zhang L,Wu J,Wei R,Zhu H,Cai G,Sun X,Chen X

更新日期：2016-11-01 00:00:00

abstract：:The preventive effect of an immunopotentiator, beta-1,6;1,3 D-glucan, on the development of diabetes and insulitis was studied in BB rats. The intravenous administration of 1 mg kg-1 week-1 of beta-1,6;1,3 D-glucan from the age of 4 weeks decreased the cumulative incidence of diabetes from 43.3% (13/30) to 6.7% (2/30)...

journal_title：Diabetes research and clinical practice

authors： Kida K,Inoue T,Kaino Y,Goto Y,Ikeuchi M,Ito T,Matsuda H,Elliott RB

更新日期：1992-08-01 00:00:00

abstract：:To clarify the diagnostic relevance of urinary type IV collagen (IV-C) and laminin in diabetic nephropathy, the excretion of these basement membrane proteins were determined by enzyme immunoassay in 172 non-insulin-dependent diabetic patients with different grades of nephropathy and 64 non-diabetic control subjects, a...

journal_title：Diabetes research and clinical practice

authors： Banu N,Hara H,Okamura M,Egusa G,Yamakido M

更新日期：1995-07-01 00:00:00

abstract：:In order to evaluate the prevalence of gestational diabetes mellitus (GDM) and the presence of risk factors for GDM, we conducted a retrospective study of a cohort of Italian women. In addition, we compared universal versus selective screening to validate the ADA's recommendations in our population. From June 1st, 199...

journal_title：Diabetes research and clinical practice

authors： Di Cianni G,Volpe L,Lencioni C,Miccoli R,Cuccuru I,Ghio A,Chatzianagnostou K,Bottone P,Teti G,Del Prato S,Benzi L

更新日期：2003-11-01 00:00:00

abstract：:We examined the effect of aldehyde-modified matrix macromolecules on mesangial cell function in vitro, using incubated rat glomerular mesangial cells. Laminin and fibronectin were modified by incubation for 24 h with 50 mM glycolaldehyde (GA), a highly reactive cross-linking glycation product, with or without equimola...

journal_title：Diabetes research and clinical practice

authors： Hasegawa G,Nakano K,Tsutsumi Y,Kondo M

更新日期：1994-02-01 00:00:00

abstract：AIMS:The objective of the present analysis was to evaluate and quantify the risk for gestational diabetes mellitus (GDM) according to maternal age. METHODS:Three electronic databases were searched for publications from inception to July 2018. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated. A dose...

journal_title：Diabetes research and clinical practice

authors： Li Y,Ren X,He L,Li J,Zhang S,Chen W

更新日期：2020-04-01 00:00:00

abstract：AIMS:To evaluate the impact on perinatal outcomes of universal gestational diabetes (GDM) screening based on 1999 WHO and IADPSG diagnostic criteria; to assess the quality of the evidence (GRADE) to support GDM screening. METHODS:Simulation of a hypothetical cohort of community-based pregnant women with 10% GDM preval...

journal_title：Diabetes research and clinical practice

authors： Falavigna M,Prestes I,Schmidt MI,Duncan BB,Colagiuri S,Roglic G

更新日期：2013-03-01 00:00:00

abstract：:We assessed peripheral and autonomic nerve function in 27 diabetics. Ten had malnutrition-related diabetes mellitus (MRDM), eight insulin-dependent diabetes mellitus (IDDM), and nine non-insulin-dependent diabetes mellitus (NIDDM). The frequency of peripheral neuropathy was 70, 78 and 13% in MRDM, NIDDM and IDDM respe...

journal_title：Diabetes research and clinical practice

authors： Sutjahjo A,Taniguchi H,Hendromartono,Tjokroprawiro A,Baba S

更新日期：1988-09-05 00:00:00

abstract：AIMS:To investigate the prevalence of undiagnosed diabetes mellitus (DM) and cardiovascular risk factors among professional drivers in Hong Kong. METHODS:Chinese professional drivers with no history of DM were invited to complete a questionnaire on their health status, followed by taking their body measurements, fasti...

journal_title：Diabetes research and clinical practice

authors： Siu SC,Wong KW,Lee KF,Lo YY,Wong CK,Chan AK,Fong DY,Lam CL

更新日期：2012-04-01 00:00:00