A modified Sindbis vector for prolonged gene expression in neurons.

abstract：:The goal of this study was to characterize the dynamics and functional connectivity of brain networks associated with fast (short-term) learning of handwriting using functional magnetic resonance imaging. Participants (n = 12) performed a graphomotor sequence learning task (naïve subjects learning to draw simple, 3-st...

journal_title：Journal of neurophysiology

authors： Swett BA,Contreras-Vidal JL,Birn R,Braun A

更新日期：2010-06-01 00:00:00

abstract：:To investigate the dependence of velocity characteristics on spatiotemporal interactions the velocity selectivity of 15 geniculate and 72 cortical cells (areas 17 and 18) was examined with light and dark bars before and after masking all but the most sensitive part of the receptive field. The use of a 0.3 degree windo...

journal_title：Journal of neurophysiology

authors： Duysens J,Orban GA,Cremieux J

更新日期：1985-10-01 00:00:00

abstract：:We studied adjustments in digit forces and moments during holding a vertically oriented handle under slow, externally imposed changes in the width of the grasp. Subjects (n = 8) grasped a customized motorized handle with five digits and held it statically in the air. The handle width either increased (expanded) or dec...

journal_title：Journal of neurophysiology

authors： Zatsiorsky VM,Gao F,Latash ML

更新日期：2006-04-01 00:00:00

abstract：:It has been suggested that successively presented sounds that are perceived as separate auditory streams are represented by separate populations of neurons. Mostly, spectral separation in different peripheral filters has been identified as the cue for segregation. However, stream segregation based on temporal cues is ...

journal_title：Journal of neurophysiology

authors： Itatani N,Klump GM

更新日期：2011-01-01 00:00:00

abstract：:Neural regions in the dorsomedial frontal cortex (DMFC), including the supplementary eye field (SEF) and the presupplementary motor area (pre-SMA), are likely candidates for generating top-down control of saccade target selection. To investigate this, we applied electrical microstimulation to these structures while sa...

journal_title：Journal of neurophysiology

authors： Yang SN,Heinen SJ,Missal M

更新日期：2008-04-01 00:00:00

abstract：:1. In alpha-chloralose-anesthetized cats the region surrounding the ventral posterolateral nucleus (VPL) of the thalamus was investigated to locate foci with input from the urinary bladder stimulated by application of intravesical pressure. The locations of the recording sites were verified in Nissl-stained histologic...

journal_title：Journal of neurophysiology

authors： Brüggemann J,Vahle-Hinz C,Kniffki KD

更新日期：1993-08-01 00:00:00

abstract：:Olfactory bulb (OB) glomeruli, the initial sites of synaptic processing of odor information, exhibit high levels of nicotinic acetylcholine receptor (nAChR) expression and receive strong cholinergic input from the basal forebrain. The role of glomerular nAChRs in olfactory processing, however, remains to be elucidated...

journal_title：Journal of neurophysiology

authors： D'Souza RD,Parsa PV,Vijayaraghavan S

更新日期：2013-10-01 00:00:00

abstract：:Neurons in the medial superior olive (MSO) are tuned to the interaural time difference (ITD) of sound arriving at the two ears. MSO neurons evoke a strongest response at their best delay (BD), at which the internal delay between bilateral inputs to MSO matches the external ITD. We performed extracellular recordings in...

journal_title：Journal of neurophysiology

authors： Day ML,Semple MN

更新日期：2011-10-01 00:00:00

abstract：:We examined how subjects plan speeded reaching movements when the precise target of the movement is not known at movement onset. Before each reach, subjects were given only a probability distribution on possible target positions. Only after completing part of the movement did the actual target appear. In separate expe...

journal_title：Journal of neurophysiology

authors： Hudson TE,Maloney LT,Landy MS

更新日期：2007-11-01 00:00:00

abstract：:The human ventral visual pathway is implicated in higher order form processing, but the organizational principles within this region are not yet well understood. Recently, Lafer-Sousa, Conway, and Kanwisher (J Neurosci 36: 1682-1697, 2016) used functional magnetic resonance imaging to demonstrate that functional respo...

journal_title：Journal of neurophysiology

authors： Goddard E

更新日期：2017-03-01 00:00:00

abstract：:Procedural skill learning requires iterative comparisons between feedback of self-generated motor output and a goal sensorimotor pattern. In juvenile songbirds, neural representations of both self-generated behaviors (each bird's own immature song) and the goal motor pattern (each bird's adult tutor song) are essentia...

journal_title：Journal of neurophysiology

authors： Yuan RC,Bottjer SW

更新日期：2019-02-01 00:00:00

abstract：:In experiments on slices (from 100- to 150-g Sprague-Dawley rats) kept at 33 degreesC, we studied the effects of brief hypoxia (2-3 min) on CA1 neurons. In whole cell recordings from submerged slices, with electrodes containing only KMeSO4 and N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid, and in the presence of...

journal_title：Journal of neurophysiology

authors： Erdemli G,Xu YZ,Krnjević K

更新日期：1998-11-01 00:00:00

abstract：:Primates can generate accurate, smooth eye-movement responses to moving target objects of arbitrary shape and size, even in the presence of complex backgrounds and/or the extraneous motion of non-target objects. Most previous studies of pursuit have simply used a spot moving over a featureless background as the target...

journal_title：Journal of neurophysiology

authors： Masson GS,Stone LS

更新日期：2002-11-01 00:00:00

abstract：:Noise is a major concern in circuits processing electrical signals, including neural circuits. There are many factors that influence how noise propagates through neural circuits, and there are few systems in which noise levels have been studied throughout a processing pathway. We recorded intracellularly from multiple...

journal_title：Journal of neurophysiology

authors： Jones PW,Gabbiani F

更新日期：2012-02-01 00:00:00

abstract：:1. Spike rates of cells in the cat's lateral superior olive (LSO) depend on interaural level differences (ILDs) and envelope interaural time differences (ITDs) of amplitude-modulated tones presented to both ears. We previously proposed that these sensitivities arise from a common mechanism, which is the IE binaural in...

journal_title：Journal of neurophysiology

authors： Joris PX

更新日期：1996-10-01 00:00:00

abstract：:Retinal degeneration (rd) leads to progressive photoreceptor cell death, resulting in vision loss. Stimulation of the inner-retinal neurons by neuroprosthetic implants is one of the clinically approved vision-restoration strategies, providing basic visual percepts to blind patients. However, little is understood as to...

journal_title：Journal of neurophysiology

authors： Stutzki H,Helmhold F,Eickenscheidt M,Zeck G

更新日期：2016-10-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:During auditory stimulation with several frequency components, distortion products (DPs) are generated as byproduct of nonlinear cochlear amplification. After generated, DP energy is reemitted into the ear channel where it can be measured as DP otoacoustic emission (DPOAE), and it also induces an excitatory response a...

journal_title：Journal of neurophysiology

authors： Abel C,Kössl M

更新日期：2009-03-01 00:00:00

abstract：:Extracellular recordings of 209 neurons were obtained with carbon fiber-containing multibarrel micropipettes. The cells were isolated in the primary somatosensory cortex of cats anesthetized with barbiturate and classified according to the nature of their response to natural stimuli, the nature of the surrounding mult...

journal_title：Journal of neurophysiology

authors： Dykes RW,Landry P,Metherate R,Hicks TP

更新日期：1984-12-01 00:00:00

abstract：:To investigate the nature of the visuomotor transformation, previous studies have used pointing tasks and examined how adaptation to a spatially localized mismatch between vision and proprioception generalizes across the workspace. Whereas some studies found extensive spatial generalization of single-point remapping, ...

journal_title：Journal of neurophysiology

authors： Malfait N,Henriques DY,Gribble PL

更新日期：2008-01-01 00:00:00

abstract：:There is evidence that postural instability associated with Parkinson's disease (PD) is not adequately improved by levodopa, implying involvement of nondopaminergic pathways. However, the mechanisms contributing to postural instability have yet to be fully identified and tested for their levodopa responsiveness. In th...

journal_title：Journal of neurophysiology

authors： Di Giulio I,St George RJ,Kalliolia E,Peters AL,Limousin P,Day BL

更新日期：2016-08-01 00:00:00

abstract：:Working memory (WM) performance is impaired by the presence of external interference. Accordingly, more efficient processing of intervening stimuli with practice may lead to enhanced WM performance. To explore the role of practice on the impact that interference has on WM performance, we studied young adults with elec...

journal_title：Journal of neurophysiology

authors： Berry AS,Zanto TP,Rutman AM,Clapp WC,Gazzaley A

更新日期：2009-09-01 00:00:00

abstract：:Several models exist for explaining primary visual cortex (V1) orientation tuning. The modified feedforward model (MFM) and the recurrent model (RM) are major examples. We have implemented these two models, at the same level of detail, alongside a few newer variations, and thoroughly compared their receptive-field str...

journal_title：Journal of neurophysiology

authors： Teich AF,Qian N

更新日期：2006-07-01 00:00:00

abstract：:Interhemispheric interactions through the corpus callosum play an important role in the control of bimanual forces. However, the extent to which physiological connections between primary motor cortices are modulated during increasing levels of bimanual force generation in intact humans remains poorly understood. Here ...

journal_title：Journal of neurophysiology

authors： Long J,Tazoe T,Soteropoulos DS,Perez MA

更新日期：2016-03-01 00:00:00

abstract：:We estimate the rates at which neurons in the primary visual cortex (V1) of anesthetized macaque monkeys transmit stimulus-related information in response to three types of visual stimulus. The stimuli-randomly modulated checkerboard patterns, stationary sinusoidal gratings, and drifting sinusoidal gratings-have very ...

journal_title：Journal of neurophysiology

authors： Reich DS,Mechler F,Victor JD

更新日期：2001-01-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:The central axons of peripherally regenerated Abeta primary sensory neurons were impaled in the dorsal columns of alpha-chloralose-anesthetized cats 9-12 mo after axotomy. The adequate peripheral stimulus was determined, and the afferent fibers intracellularly stimulated while simultaneously recording the resulting co...

journal_title：Journal of neurophysiology

authors： Koerber HR,Mirnics K,Kavookjian AM,Light AR

更新日期：1999-04-01 00:00:00

abstract：:Primary motor cortex has been studied for more than a century, yet a consensus on its functional contribution to movement control is still out of reach. In particular, there remains controversy as to the level of control produced by motor cortex ("low-level" movement dynamics vs. "high-level" movement kinematics) and ...

journal_title：Journal of neurophysiology

authors： Omrani M,Kaufman MT,Hatsopoulos NG,Cheney PD

更新日期：2017-09-01 00:00:00

abstract：:The pre-Bötzinger complex (preBötC) underlies inspiratory rhythm generation. As a result of network interactions, preBötC neurons burst synchronously to produce rhythmic premotor inspiratory activity. Each inspiratory burst consists of action potentials (APs) on top of a 10- to 20-mV synchronous depolarization lasting...

journal_title：Journal of neurophysiology

authors： Morgado-Valle C,Fernandez-Ruiz J,Lopez-Meraz L,Beltran-Parrazal L

更新日期：2015-02-15 00:00:00

abstract：:1. The responses of single neurons in the primary somatosensory cortex of the cat to brief air-pulse stimuli were quantitatively examined. These controlled natural stimuli activated almost exclusively rapidly adapting hair units which, on systematic movement of the stimulus through the receptive field, gave unit-respo...

journal_title：Journal of neurophysiology

authors： Laskin SE,Spencer WA

更新日期：1979-07-01 00:00:00