Abstract:
:The goal of this study was to characterize the dynamics and functional connectivity of brain networks associated with fast (short-term) learning of handwriting using functional magnetic resonance imaging. Participants (n = 12) performed a graphomotor sequence learning task (naïve subjects learning to draw simple, 3-stroke Chinese word characters), which focused the learning process on the kinematic aspects of sequence learning instead of on the production of the line segments. Learning of the graphomotor sequence was demonstrated by a progressive improvement in movement smoothness as assessed by normalized jerk scores. Examination of the patterns of regional neural activity and functional connectivity during sequence learning demonstrated that cortical regions, which may support visuomotor mapping components of the task, were active prior to subcortical areas that may play a role in encoding and refining the novel sequences. Importantly, differences in the time course of recruitment of basal ganglia and cerebellar networks suggest distinct but integrated roles in the encoding and refining of the handwritten sequences. This implies multiple kinematic representations of graphomotor trajectories may be encoded at various spatiotemporal scales.
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Swett BA,Contreras-Vidal JL,Birn R,Braun Adoi
10.1152/jn.00449.2009subject
Has Abstractpub_date
2010-06-01 00:00:00pages
3366-77issue
6eissn
0022-3077issn
1522-1598pii
jn.00449.2009journal_volume
103pub_type
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