Perspectives on classical controversies about the motor cortex.

abstract：:1. Somatic K currents of cultured hippocampal, striatal, and spinal cord neurons of embryonic rat were recorded under voltage clamp in membrane spheres ("blebs") excised by means of a tight-seal pipette. 2. The somatic K current in blebs was subject to rapid and near complete inactivation during 300-ms depolarizations...

journal_title：Journal of neurophysiology

authors： Rizzo MA,Nonner W

更新日期：1992-11-01 00:00:00

abstract：:We recently reported evidence indicating that selective attention is deployed to a target location in a multi-object display, when the target event (a change of one of the objects) is preceded by subliminal flicker in the gamma range. However, concerns have been raised regarding the stimuli used in this study and the ...

journal_title：Journal of neurophysiology

authors： Cheadle SW,Parton A,Müller HJ,Usher M

更新日期：2011-02-01 00:00:00

abstract：:Much has been studied and written about plastic changes in the CNS of humans triggered by events such as limb amputation. However, little is known about the extent to which the original pathways retain residual function after peripheral amputation. Our earlier, acute study on long-term amputees indicated that central ...

journal_title：Journal of neurophysiology

authors： Dhillon GS,Krüger TB,Sandhu JS,Horch KW

更新日期：2005-05-01 00:00:00

abstract：:Fast oscillatory activity (more than approximately 200 Hz) has been attracting increasing attention regarding its possible role in both normal brain function and epileptogenesis. Yet, its underlying cellular mechanism remains poorly understood. Our prior investigation of the phenomenon in rat somatosensory cortex indi...

journal_title：Journal of neurophysiology

authors： Jones MS,Barth DS

更新日期：2002-08-01 00:00:00

abstract：:1. Previous studies indicate that after transection of the rostral spinal cord, larval lamprey begin to recover locomotor behavior 2 wk posttransection and recovery is complete at approximately 8 wk. To examine the mechanisms underlying behavioral recovery after spinal cord transection, in the present study the time c...

journal_title：Journal of neurophysiology

authors： McClellan AD

更新日期：1994-08-01 00:00:00

abstract：:1. Hindlimb paw-shake responses were assessed before and after unilateral deafferentation (L3-S1) in chronic-spinal cats (n = 5), spinalized at the T12 level 1 yr earlier. Selected ankle flexor [tibialis anterior (TA)] and extensor [lateral gastrocnemius (LG)] and knee extensor [vastus lateralis (VL)] muscles were sur...

journal_title：Journal of neurophysiology

authors： Koshland GF,Smith JL

更新日期：1989-07-01 00:00:00

abstract：:The perforant path forms a monosynaptic connection between the cells of layer II of the entorhinal cortex and the pyramidal cells in hippocampal area CA3. Although this projection is prominent anatomically, very little is known about the physiological properties of this input. The distal location of these synapses sug...

journal_title：Journal of neurophysiology

authors： Urban NN,Henze DA,Barrionuevo G

更新日期：1998-09-01 00:00:00

abstract：:Many electrophysiologists view neurotransmitter transporters as tiny vacuum cleaners, operating continuously to lower extracellular neurotransmitter concentration to zero. However, this is not consistent with their known behavior, instead only reducing extracellular neurotransmitter concentration to a finite, nonzero ...

journal_title：Journal of neurophysiology

authors： Richerson GB,Wu Y

更新日期：2003-09-01 00:00:00

abstract：:EEG oscillations are hypothesized to reflect cyclical variations in the neuronal excitability, with particular frequency bands reflecting differing spatial scales of brain operation. However, despite decades of clinical and scientific investigation, there is no unifying theory of EEG organization, and the role of ongo...

journal_title：Journal of neurophysiology

authors： Lakatos P,Shah AS,Knuth KH,Ulbert I,Karmos G,Schroeder CE

更新日期：2005-09-01 00:00:00

abstract：:The mechanisms underlying the depression of evoked fast excitatory postsynaptic currents (EPSCs) following superfusion with medium deprived of oxygen and glucose (in vitro ischemia) for a 4-min period in hippocampal CA1 neurons were investigated in rat brain slices. The amplitude of evoked fast EPSCs decreased by 85 +...

journal_title：Journal of neurophysiology

authors： Tanaka E,Yasumoto S,Hattori G,Niiyama S,Matsuyama S,Higashi H

更新日期：2001-09-01 00:00:00

abstract：:1. The discharge patterns and axonal projections of saccadic long-lead burst neurons (LLBNs) with somata in the pontine reticular formation were studied in alert squirrel monkeys with the use of the method of intraaxonal recording and horseradish peroxidase injection. 2. The largest population of stained neurons were ...

journal_title：Journal of neurophysiology

authors： Scudder CA,Moschovakis AK,Karabelas AB,Highstein SM

更新日期：1996-07-01 00:00:00

abstract：:Modulation of sacral spinal dorsal horn neurons by the ventrolateral PAG was studied by extracellular recording combined with microiontophoretic applications of alpha-adrenergic agonists or antagonists. Bicuculline (BIC, 15 ng) microinjected into the ventrolateral PAG produced a consistent inhibition of the responses ...

journal_title：Journal of neurophysiology

authors： Budai D,Harasawa I,Fields HL

更新日期：1998-11-01 00:00:00

abstract：:Populations of output neurons in the mammalian olfactory bulb (OB) exhibit distinct, widespread spatial and temporal activation patterns when stimulated with odorants. However, questions remain as to how ensembles of mitral/tufted (M/T) neurons in the mammalian OB represent odorant information. In this report, the sin...

journal_title：Journal of neurophysiology

authors： Lehmkuhle MJ,Normann RA,Maynard EM

更新日期：2006-03-01 00:00:00

abstract：:Distractions affect postural control, but this mechanism is not well understood. Diversion of resources during cognitive stress may lead to decreased motor drive and postural muscle tone. This may appear as decreased postural stiffness and increased postural sway amplitude. We hypothesized that dual tasking leads to d...

journal_title：Journal of neurophysiology

authors： Kang HG,Lipsitz LA

更新日期：2010-12-01 00:00:00

abstract：:In the visual, auditory, and electrosensory modalities, stimuli are defined by first- and second-order attributes. The fast time-pressure signal of a sound, a first-order attribute, is important, for instance, in sound localization and pitch perception, while its slow amplitude-modulated envelope, a second-order attri...

journal_title：Journal of neurophysiology

authors： Fontaine B,MacLeod KM,Lubejko ST,Steinberg LJ,Köppl C,Peña JL

更新日期：2014-07-15 00:00:00

abstract：:Electrically excitable cells have voltage-dependent ion channels on the plasma membrane that regulate membrane permeability to specific ions. Voltage-gated Ca(2+) channels (VGCCs) are especially important as Ca(2+) serves as both a charge carrier and second messenger. Zebrafish (Danio rerio) are an important model ver...

journal_title：Journal of neurophysiology

authors： Won YJ,Ono F,Ikeda SR

更新日期：2011-01-01 00:00:00

abstract：:Humans with spinal cord injury (SCI) modulate locomotor output in response to limb load. Understanding the neural control mechanisms responsible for locomotor adaptation could provide a framework for selecting effective interventions. We quantified feedback and feedforward locomotor adaptations to limb load modulation...

journal_title：Journal of neurophysiology

authors： Gordon KE,Wu M,Kahn JH,Schmit BD

更新日期：2010-09-01 00:00:00

abstract：:Neurons in the medial superior olive (MSO) are tuned to the interaural time difference (ITD) of sound arriving at the two ears. MSO neurons evoke a strongest response at their best delay (BD), at which the internal delay between bilateral inputs to MSO matches the external ITD. We performed extracellular recordings in...

journal_title：Journal of neurophysiology

authors： Day ML,Semple MN

更新日期：2011-10-01 00:00:00

abstract：:In human spinal cord injury (SCI), imposed unilateral hip movements trigger multijoint, coordinated reflexes that might incorporate interneuronal circuitry involved in normal motor control, such as neural pathways associated with the reflex control of locomotion. To further investigate the complexity of these hip-trig...

journal_title：Journal of neurophysiology

authors： Onushko T,Schmit BD

更新日期：2007-10-01 00:00:00

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:Paw-shake responses (PSRs) were evoked by wrapping masking tape around the hind-paw in nine cats spinalized at the T12 level either at 2 or 12 wk of age or as young adults (10-12 mo). Electromyographic responses of ankle extensors (LG and SOL) and one ankle flexor (TA) were recorded through the 6th mo after cord trans...

journal_title：Journal of neurophysiology

authors： Sabin C,Smith JL

更新日期：1984-04-01 00:00:00

abstract：:The discharge of muscle spindle afferents from monkey spindle afferents from monkey jaw-closing muscles was studied during mastication of natural foods by extracellular recording from the fibers or cell bodies of the tract and mesencephalic nucleus of the fifth nerve. In all, 39 muscle afferents were studied. The spin...

journal_title：Journal of neurophysiology

authors： Goodwin GM,Luschei ES

更新日期：1975-05-01 00:00:00

abstract：:In mesial temporal lobe (MTL) epilepsy, which typically involves the hippocampus (HPC), epileptiform events are enhanced during slow wave sleep (SWS). It remains unclear how and why the electroencephalographic (EEG) states that constitute SWS might predispose the HPC to this type of pathological activity. Recently our...

journal_title：Journal of neurophysiology

authors： Nazer F,Dickson CT

更新日期：2009-09-01 00:00:00

abstract：:In humans with temporal lobe epilepsy and kainate-treated rats, the mossy fibers of the dentate granule cells send collateral axons into the inner molecular layer. Prior investigations on kainate-treated rats demonstrated that abnormal hilar-evoked events can occasionally be observed in slices with mossy fiber sprouti...

journal_title：Journal of neurophysiology

authors： Patrylo PR,Dudek FE

更新日期：1998-01-01 00:00:00

abstract：:Identifying the properties of correlations in the firing of neocortical neurons is central to our understanding of cortical information processing. It has been generally assumed, by virtue of the columnar organization of the neocortex, that the firing of neurons residing in a certain vertical domain is highly correlat...

journal_title：Journal of neurophysiology

authors： Reyes-Puerta V,Amitai Y,Sun JJ,Shani I,Luhmann HJ,Shamir M

更新日期：2015-05-01 00:00:00

abstract：:Gramicidin-perforated patch-clamp recordings were made from slices of the suprachiasmatic nucleus (SCN) of adult rats to characterize the role of gamma-amino butyric acid (GABA) in the circadian timing system. During the day, activation of GABA(A) receptors hyperpolarized the membrane of SCN neurons. During the night,...

journal_title：Journal of neurophysiology

authors： De Jeu M,Pennartz C

更新日期：2002-02-01 00:00:00

abstract：:Synaptic interactions between nearby excitatory and inhibitory neurons in the neocortex are thought to play fundamental roles in sensory processing. Here, we have combined optogenetic stimulation, whole cell recordings, and computational modeling to define key functional microcircuits within layer 2/3 of mouse primary...

journal_title：Journal of neurophysiology

authors： Avermann M,Tomm C,Mateo C,Gerstner W,Petersen CC

更新日期：2012-06-01 00:00:00

abstract：:1. Outward currents in identified cell types from the pyloric system of the stomatogastric ganglion (STG) of the spiny lobster, Panulirus marginatus, were studied under two-microelectrode voltage clamp. A comparison was made between data from intact cells and somata isolated by ligation of the primary neurite of these...

journal_title：Journal of neurophysiology

authors： Hartline DK,Gassie DV,Jones BR

更新日期：1993-06-01 00:00:00

abstract：:We report a novel phenomenon produced by focused ultrasound (US) that may be important for understanding its effects on cell membranes. When a US burst (2.1 MHz, 1-mm focal diameter, 0.1-1 MPa) was focused on a motor axon of the crayfish neuromuscular junction, it consistently produced a fast hyperpolarization, which ...

journal_title：Journal of neurophysiology

authors： Lin JW,Yu F,Müller WS,Ehnholm G,Okada Y

更新日期：2019-02-01 00:00:00

abstract：:Hilar mossy cells represent a unique population of local circuit neurons in the hippocampus and dentate gyrus. Here we use electrophysiological techniques in acute preparations of hippocampal slices to demonstrate that depolarization of a single hilar mossy cell can produce robust inhibition of local GABAergic afferen...

journal_title：Journal of neurophysiology

authors： Hofmann ME,Nahir B,Frazier CJ

更新日期：2006-11-01 00:00:00