Mechanisms underlying the depression of evoked fast EPSCs following in vitro ischemia in rat hippocampal CA1 neurons.

abstract：:The purpose of this study was to compare the discharge characteristics of motor units recruited during an isometric contraction that was sustained with the elbow flexor muscles by older adults at target forces that were less than the recruitment threshold force of each isolated motor unit. The discharge times of 27 si...

journal_title：Journal of neurophysiology

authors： Pascoe MA,Holmes MR,Enoka RM

更新日期：2011-02-01 00:00:00

abstract：:The aim of this study was to examine whether subjects who have learned a skilled locomotor task can transfer the acquired performance to conditions involving either a change in the external coordinates or in the sensory input from one leg. Subjects were trained to step over an obstacle with minimal foot clearance with...

journal_title：Journal of neurophysiology

authors： Lam T,Dietz V

更新日期：2004-10-01 00:00:00

abstract：:1. The effects of gamma-aminobutyric acid (GABA) and glycine and their respective antagonists were determined for neurons in the mouse superior olivary complex. Brain slices (400 microns) were cut in the frontal plane and maintained in an oxygenated saline solution for physiological recording. Recordings were made fro...

journal_title：Journal of neurophysiology

authors： Wu SH,Kelly JB

更新日期：1995-01-01 00:00:00

abstract：:Children with secondary dystonia due to cerebral palsy exhibit abnormal upper extremity postures and slow voluntary movement. However, the interaction between abnormal postures and abnormal movement in dystonia is still unclear. Some mechanisms by which postures are maintained in dystonia include stretch reflexes, ove...

journal_title：Journal of neurophysiology

authors： Kukke SN,Sanger TD

更新日期：2011-05-01 00:00:00

abstract：:The external anal sphincter (EAS) is important for the maintenance of bowel continence and may be compromised by a variety of neuropathic conditions. However, large animal models for the study of EAS functions have been sparse. The EAS guarding reflex was examined by electromyography (EMG) in neurologically intact rhe...

journal_title：Journal of neurophysiology

authors： Chang HH,Lee U,Vu T,Pikov V,Nieto JH,Christe KL,Havton LA

更新日期：2018-12-01 00:00:00

abstract：:The excitotoxic theory of Parkinson's disease (PD) hypothesizes that a pathophysiological degeneration of dopaminergic neurons stems from neural hyperactivity at early stages of disease, leading to mitochondrial stress and cell death. Recent research has harnessed the visual system of Drosophila PD models to probe thi...

journal_title：Journal of neurophysiology

authors： Himmelberg MM,West RJH,Elliott CJH,Wade AR

更新日期：2018-03-01 00:00:00

abstract：:The basal ganglia participate in motor functions and are implicated in the pathophysiology of movement disorders. It has been shown in primates that the activity of many neurons in one of the basal ganglia output nuclei, the internal segment of the globus pallidus, changes with active or passive movements. The involve...

journal_title：Journal of neurophysiology

authors： Wichmann T,Kliem MA

更新日期：2004-02-01 00:00:00

abstract：:1. Whole cell patch-clamp techniques, combined with direct visualization of neurons, were used to study voltage-dependent potassium currents in layer 1 neurons and layer II/III pyramidal cells. 2. In the presence of tetrodotoxin, step depolarizations evoked an outward current. This current had a complex waveform and a...

journal_title：Journal of neurophysiology

authors： Zhou FM,Hablitz JJ

更新日期：1996-08-01 00:00:00

abstract：:A major goal of neuroscience is to understand the functions of networks of neurons in cognition and behavior. Recent work has focused on implanting arrays of ∼100 immovable electrodes or smaller numbers of individually adjustable electrodes, designed to target a few cortical areas. We have developed a recording system...

journal_title：Journal of neurophysiology

authors： Feingold J,Desrochers TM,Fujii N,Harlan R,Tierney PL,Shimazu H,Amemori K,Graybiel AM

更新日期：2012-04-01 00:00:00

abstract：:Iontophoresis of glutamate at sites on the apical dendrite 278-555 microm from the somata of rat neocortical pyramidal neurons evoked low-threshold, small, slow spikes and/or large, fast spikes in 71% of recorded cells. The amplitude of the small, slow spikes recorded at the soma averaged 9.1 mV, and their apparent th...

journal_title：Journal of neurophysiology

authors： Schwindt PC,Crill WE

更新日期：1997-05-01 00:00:00

abstract：:1. The vibratory response to two-tone stimuli was measured in the basilar membrane of the chinchilla cochlea by means of the Mössbauer technique or laser velocimetry. Measurements were made at sites with characteristic frequency (CF, the frequency at which an auditory structure is most sensitive) of 7-10 kHz, located ...

journal_title：Journal of neurophysiology

authors： Ruggero MA,Robles L,Rich NC

更新日期：1992-10-01 00:00:00

abstract：:1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

journal_title：Journal of neurophysiology

authors： Cliffer KD,Hasegawa T,Willis WD

更新日期：1992-09-01 00:00:00

abstract：:Single, teased fiber recordings were made from the decentralized right cervical vagus nerve (hyponodal) of the rat. A total of 67 afferent fibers that responded to gastric distension (GD) were studied: 9 fibers were stimulated by phasic balloon GD, 58 by more natural fluid GD. All balloon GD-responsive fibers had rest...

journal_title：Journal of neurophysiology

authors： Ozaki N,Sengupta JN,Gebhart GF

更新日期：1999-11-01 00:00:00

abstract：:We investigated the precision of spike timing in a model of gap junction-coupled oscillatory neurons. The model incorporated the known physiology, morphology, and connectivity of the weakly electric fish's high-frequency and extremely precise pacemaker nucleus (Pn). Two neuron classes, pacemaker and relay cells, were ...

journal_title：Journal of neurophysiology

authors： Moortgat KT,Bullock TH,Sejnowski TJ

更新日期：2000-02-01 00:00:00

abstract：:The horizontal cell is a second-order retinal neuron that is depolarized in the dark and responds to light with graded potential changes. In such a nonspiking neuron, not only the voltage-gated ionic conductances but also Ca(2+) regulation mechanisms, e.g., the Na(+)/Ca(2+) exchange and the Ca(2+) pump, are considered...

journal_title：Journal of neurophysiology

authors： Hayashida Y,Yagi T

更新日期：2002-01-01 00:00:00

abstract：:The problem of how the hippocampus encodes both spatial and nonspatial information at the cellular network level remains largely unresolved. Spatial memory is widely modeled through the theoretical framework of attractor networks, but standard computational models can only represent spaces that are much smaller than t...

journal_title：Journal of neurophysiology

authors： Hedrick KR,Zhang K

更新日期：2016-08-01 00:00:00

abstract：:High-frequency burstlike electrical conditioning stimulation (HFS) applied to human skin induces an increase in mechanical pinprick sensitivity of the surrounding unconditioned skin (a phenomenon known as secondary hyperalgesia). The present study assessed the effect of frequency of conditioning stimulation on the dev...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Gousset S,Bouvy J,Stouffs A,Lebrun L,van Neerven SGA,Mouraux A

更新日期：2019-09-01 00:00:00

abstract：:Microsleeps are brief episodes of arousal level decrease manifested through behavioral signs. Brain activity during microsleep in the presence of external stimulus remains poorly understood. In this study, we sought to understand neural responses to auditory stimulation during microsleep. We gave participants the simp...

journal_title：Journal of neurophysiology

authors： Yong Z,Tan JH,Hsieh PJ

更新日期：2019-12-01 00:00:00

abstract：:The cerebellum was historically considered a brain region dedicated to motor control, but it has become clear that it also contributes to sensory processing, particularly when sensory discrimination is required. Prior work, for example, has demonstrated a cerebellar contribution to sensory discrimination in the visual...

journal_title：Journal of neurophysiology

authors： Dahlem K,Valko Y,Schmahmann JD,Lewis RF

更新日期：2016-05-01 00:00:00

abstract：:We have shown previously that in the acutely spinalized anesthetized rat the activities of many dorsal horn interneurons (DHN) at the T(10) level are correlated positively with both ongoing and stimulus-evoked renal sympathetic nerve activity (RSNA) and therefore may belong to networks generating RSNA after acute, cer...

journal_title：Journal of neurophysiology

authors： Chau D,Johns DG,Schramm LP

更新日期：2000-05-01 00:00:00

abstract：:1. We investigated gamma-aminobutyric acid (GABA) receptors using thin slice patch-clamp techniques in the swellings along axons of posterior pituitary nerve terminals. 2. Activation of the nerve terminal GABAA receptor induced a mean conductance change of 1.5 nS. Normalizing to area gave a mean conductance density of...

journal_title：Journal of neurophysiology

authors： Zhang SJ,Jackson MB

更新日期：1995-03-01 00:00:00

abstract：:The responses of low-frequency, primary-like neurons of the ventral cochlear nucleus were measured as a function of signal-to-noise ratio for gated tonal signals and noise maskers that were varied in bandwidth and duration. For a given signal-to-noise ratio, each of the maskers is known to produce the same amount of m...

journal_title：Journal of neurophysiology

authors： Langford TL

更新日期：1983-12-01 00:00:00

abstract：:Recent findings indicate that monkeys can report their confidence in perceptual decisions and that this information is encoded in neurons involved in making decisions, including the lateral intraparietal area (LIP) and the supplementary eye field (SEF). A key issue to consider when studying confidence is that decision...

journal_title：Journal of neurophysiology

authors： Grimaldi P,Cho SH,Lau H,Basso MA

更新日期：2018-11-01 00:00:00

abstract：:Over the past 3 decades, various algorithms used to decompose the electromyographic (EMG) signal into its constituent motor unit action potentials (MUAPs) have been reported. All are limited to decomposing EMG signals from isometric contraction. In this report, we describe a successful approach to decomposing the surf...

journal_title：Journal of neurophysiology

authors： De Luca CJ,Chang SS,Roy SH,Kline JC,Nawab SH

更新日期：2015-03-15 00:00:00

abstract：:There is a great need to develop new approaches for rehabilitation of the upper limb after stroke. Robotic therapy is a promising form of neurorehabilitation that can be delivered in higher doses than conventional therapy. Here we sought to determine whether the reported effects of robotic therapy, which have been bas...

journal_title：Journal of neurophysiology

authors： Kitago T,Goldsmith J,Harran M,Kane L,Berard J,Huang S,Ryan SL,Mazzoni P,Krakauer JW,Huang VS

更新日期：2015-09-01 00:00:00

abstract：:We explored how contour information in primary visual cortex might be embedded in the simultaneous activity of multiple cells recorded with a 100-electrode array. Synchronous activity in cat visual cortex was more selective and predictable in discriminating between drifting grating and concentric ring stimuli than cha...

journal_title：Journal of neurophysiology

authors： Samonds JM,Zhou Z,Bernard MR,Bonds AB

更新日期：2006-04-01 00:00:00

abstract：:Anatomical and physiological data have implicated the pretectal olivary nucleus (PON) as the midbrain relay for the pupillary light reflex in a variety of species. To determine the nature of the discharge of pretectal light reflex relay neurons, we recorded their activity in monkeys that were fixating a stationary spo...

journal_title：Journal of neurophysiology

authors： Pong M,Fuchs AF

更新日期：2000-08-01 00:00:00

abstract：:1. Human flexor reflex (HFR) responses were elicited during ergometer cycling in neurologically intact humans with the objective of understanding the influence of lower limb muscle activity on phase-dependent reflex modulation during movement. The experimental setup permitted control over background muscle activity an...

journal_title：Journal of neurophysiology

authors： Brown DA,Kukulka CG

更新日期：1993-04-01 00:00:00

abstract：:The oculomotor system is well understood compared with other motor systems; however, we do not yet know the spatial details of sensory to motor transformations. This study addresses this issue by quantifying the spatial relationships between visual and motor responses in the superior colliculus (SC), a midbrain struct...

journal_title：Journal of neurophysiology

authors： Marino RA,Rodgers CK,Levy R,Munoz DP

更新日期：2008-11-01 00:00:00

abstract：:1. We investigated the effects of metabotropic glutamate (mGlu) receptor activation on intracellular Ca2+ concentration ([Ca2+]i) in the soma and dendrites of hippocampal CA1 pyramidal neurons. Changes in [Ca2+]i were measured using confocal imaging simultaneously with whole-cell recording techniques. Differences in [...

journal_title：Journal of neurophysiology

authors： Jaffe DB,Brown TH

更新日期：1994-07-01 00:00:00