Robotic therapy for chronic stroke: general recovery of impairment or improved task-specific skill?

abstract：:In rats, whisker trimming during development leads to persistent alterations in the function of cortical barrel circuits and to behavioral deficits later in life. Here we examined how whisker trimming begun either at birth (P0) or on postnatal day 12 (P12), around the onset of whisking behavior, affects receptive fiel...

journal_title：Journal of neurophysiology

authors： Shoykhet M,Land PW,Simons DJ

更新日期：2005-12-01 00:00:00

abstract：:The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...

journal_title：Journal of neurophysiology

authors： Nicholson DA,Freeman JH Jr

更新日期：2003-10-01 00:00:00

abstract：:We estimate the rates at which neurons in the primary visual cortex (V1) of anesthetized macaque monkeys transmit stimulus-related information in response to three types of visual stimulus. The stimuli-randomly modulated checkerboard patterns, stationary sinusoidal gratings, and drifting sinusoidal gratings-have very ...

journal_title：Journal of neurophysiology

authors： Reich DS,Mechler F,Victor JD

更新日期：2001-01-01 00:00:00

abstract：:Previous studies have shown that intracortical inhibition (ICI) plays an important role in shaping the output from primary motor cortex (M1). This study explored the muscle specificity and temporal modulation of ICI during the performance of a phasic index finger flexion task. Fifteen subjects were asked to rest their...

journal_title：Journal of neurophysiology

authors： Stinear CM,Byblow WD

更新日期：2003-04-01 00:00:00

abstract：:1. Discharges of neurons in the peripheral auditory system contain information about the temporal features of acoustic stimuli. Phase-locking of neurons in the anteroventral cochlear nucleus (AVCN) is usually reported to be less robust than in auditory nerve (AN) fibers, which provide their major input. In a companion...

journal_title：Journal of neurophysiology

authors： Joris PX,Smith PH,Yin TC

更新日期：1994-03-01 00:00:00

abstract：:Previous studies have shown that regional slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep is modulated by prior experience and learning. Although this effect has been convincingly demonstrated for the sensorimotor domain, attempts to extend these findings to the visual system have provided mixed re...

journal_title：Journal of neurophysiology

authors： Bernardi G,Betta M,Cataldi J,Leo A,Haba-Rubio J,Heinzer R,Cirelli C,Tononi G,Pietrini P,Ricciardi E,Siclari F

更新日期：2019-06-01 00:00:00

abstract：:Avian auditory and vestibular hair cells regenerate after damage by ototoxic drugs, but until recently there was little evidence that regenerated vestibular hair cells function normally. In an earlier study we showed that the vestibuloocular reflex (VOR) is eliminated with aminoglycoside antibiotic treatment and recov...

journal_title：Journal of neurophysiology

authors： Goode CT,Carey JP,Fuchs AF,Rubel EW

更新日期：1999-03-01 00:00:00

abstract：:The cortical N1 response to balance perturbation is observed in electroencephalography recordings simultaneous to automatic balance-correcting muscle activity. We recently observed larger cortical N1s in individuals who had greater difficulty resisting compensatory steps, suggesting the N1 may be influenced by steppin...

journal_title：Journal of neurophysiology

authors： Payne AM,Ting LH

更新日期：2020-12-01 00:00:00

abstract：:The increasing use of transgenic mice for the study of pain mechanisms necessitates comprehensive understanding of the murine somatosensory system. Using an in vivo mouse preparation, we studied response properties of tibial nerve afferent fibers innervating glabrous skin. Recordings were obtained from 225 fibers iden...

journal_title：Journal of neurophysiology

authors： Cain DM,Khasabov SG,Simone DA

更新日期：2001-04-01 00:00:00

abstract：:This study investigated how the ability to extend the fingers and thumb recovers early after stroke and how the ability to extend all of the digits affects grasping performance. We studied 24 hemiparetic patients at 3 and 13 wk post stroke. At each visit, we tested the subjects' ability to actively extend all five dig...

journal_title：Journal of neurophysiology

authors： Lang CE,DeJong SL,Beebe JA

更新日期：2009-07-01 00:00:00

abstract：:Converging inputs to the entorhinal cortex from the piriform cortex and medial septum: facilitation and current source density analysis. J. Neurophysiol. 78: 2602-2615, 1997. The entorhinal cortex receives sensory inputs from the piriform cortex and modulatory inputs from the medial septum. To examine short-term synap...

journal_title：Journal of neurophysiology

authors： Chapman CA,Racine RJ

更新日期：1997-11-01 00:00:00

abstract：:Older adults are at a high risk of falls, and most falls occur during locomotor activities like walking. This study aimed to improve our understanding of changes in neuromuscular control associated with increased risk of falls in older adults in the presence of dynamic balance challenges during walking. Motor module (...

journal_title：Journal of neurophysiology

authors： Allen JL,Franz JR

更新日期：2018-11-01 00:00:00

abstract：:Action-potential propagation into the axon terminals of olfactory receptor cells was measured with the use of voltage-sensitive dye imaging in the isolated spiny lobster brain. Conditioning shocks to the olfactory nerve, known to cause long-lasting suppression of olfactory lobe neurons, allowed the selective imaging o...

journal_title：Journal of neurophysiology

authors： Wachowiak M,Cohen LB

更新日期：1998-08-01 00:00:00

abstract：:The structural elements of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) signaling pathway have been described in the vestibular peripheral system. However, the functions of NO in the vestibular endorgans are still not clear. We evaluated the action of NO on the Ca(2+) currents in hair cells isolated from ...

journal_title：Journal of neurophysiology

authors： Almanza A,Navarrete F,Vega R,Soto E

更新日期：2007-02-01 00:00:00

abstract：:1. The sensorimotor synapse of Aplysia expresses various shortlasting changes in synaptic efficacy including homosynaptic depression (HSD) and heterosynaptic facilitation by serotonin (5-HT) either at nondepressed sensory neuron (SN) synaptic connections or at SN synaptic connections first depressed by HSD. We examine...

journal_title：Journal of neurophysiology

authors： Sun ZY,Schacher S

更新日期：1996-10-01 00:00:00

abstract：:Previous studies have described maturational changes in GABAergic inhibitory synaptic transmission in the rodent somatosensory cortex during the early postnatal period. To determine whether alterations in the functional properties of synaptically localized GABA(A) receptors (GABA(A)Rs) contribute to development of inh...

journal_title：Journal of neurophysiology

authors： Dunning DD,Hoover CL,Soltesz I,Smith MA,O'Dowd DK

更新日期：1999-12-01 00:00:00

abstract：:Some electrographic seizures are generated intracortically. The cellular and ionic bases of cortically generated spontaneous seizures are not fully understood. Here we investigated spontaneously occurring seizures consisting of spike-wave complexes intermingled with fast runs in ketamine-xylazine anesthetized cats, us...

journal_title：Journal of neurophysiology

authors： Timofeev I,Grenier F,Steriade M

更新日期：2004-08-01 00:00:00

abstract：:1. This paper examines the electrophysiological properties of cultured rat adrenal chromaffin cells at different stages of neuron-like morphological differentiation in response to nerve growth factor (NGF). 2. Chromaffin cells display a large variability in the morphological changes after exposure to NGF. However, a m...

journal_title：Journal of neurophysiology

authors： Islas-Suárez L,Gómez-Chavarín M,Drucker-Colín R,Hernández-Cruz A

更新日期：1994-10-01 00:00:00

abstract：:Neurons in primary visual cortex are selective to the orientation and spatial frequency of sinusoidal gratings. In the classic model of cortical organization, a population of neurons responding to the same region of the visual field but tuned to all possible feature combinations provides a detailed representation of t...

journal_title：Journal of neurophysiology

authors： Jimenez LO,Tring E,Trachtenberg JT,Ringach DL

更新日期：2018-07-01 00:00:00

abstract：:Synaptic transmission throughout most of the CNS is steeply dependent on presynaptic calcium influx through the voltage-gated calcium channels Cav2.1-Cav2.3. In addition to triggering exocytosis, this calcium influx also recruits short-term synaptic plasticity. During the complex patterns of presynaptic activity that ...

journal_title：Journal of neurophysiology

authors： Ricoy UM,Frerking ME

更新日期：2014-06-15 00:00:00

abstract：:Similar to most visual animals, crabs perform proper avoidance responses to objects directly approaching them. The monostratified lobula giant neurons of type 1 (MLG1) of crabs constitute an ensemble of 14-16 bilateral pairs of motion-detecting neurons projecting from the lobula (third optic neuropile) to the midbrain...

journal_title：Journal of neurophysiology

authors： Oliva D,Tomsic D

更新日期：2014-09-15 00:00:00

abstract：:Training rats to perform rapidly and efficiently in an olfactory discrimination task results in robust enhancement of excitatory and inhibitory synaptic connectivity in the rat piriform cortex, which is maintained for days after training. To explore the mechanisms by which such synaptic enhancement occurs, we recorded...

journal_title：Journal of neurophysiology

authors： Saar D,Reuveni I,Barkai E

更新日期：2012-02-01 00:00:00

abstract：:The acid-sensing ion channels (ASICs) form cation channels that are transiently activated by extracellular protons. They are expressed in dorsal root ganglia (DRG) neurons and in the periphery where they play a function in nociception and mechanosensation. Previous studies showed that FMRFamide and related peptides po...

journal_title：Journal of neurophysiology

authors： Xie J,Price MP,Wemmie JA,Askwith CC,Welsh MJ

更新日期：2003-05-01 00:00:00

abstract：:The relationship among neonatal seizures, abnormalities of the electroencephalogram (EEG), brain injury, and long-term neurological outcome (e.g., epilepsy) remains controversial. The effects of hypoxia alone (Ha) and hypoxia-ischemia (HI) were studied in neonatal rats at postnatal day 7; both models generate EEG seiz...

journal_title：Journal of neurophysiology

authors： Zayachkivsky A,Lehmkuhle MJ,Ekstrand JJ,Dudek FE

更新日期：2015-11-01 00:00:00

abstract：:The electrical activity of 168 individual neurons located in the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis, and ventralis, has been recorded in precollicular decerebrate cats during sinusoidal tilt about the longitudinal axis of the whole...

journal_title：Journal of neurophysiology

authors： Manzoni D,Pompeiano O,Stampacchia G,Srivastava UC

更新日期：1983-11-01 00:00:00

abstract：:In the mammalian vestibular periphery, electrical activation of the efferent vestibular system (EVS) has two effects on afferent activity: 1) it increases background afferent discharge and 2) decreases afferent sensitivity to rotational stimuli. Although the cellular mechanisms underlying these two contrasting afferen...

journal_title：Journal of neurophysiology

authors： Poppi LA,Tabatabaee H,Drury HR,Jobling P,Callister RJ,Migliaccio AA,Jordan PM,Holt JC,Rabbitt RD,Lim R,Brichta AM

更新日期：2018-01-01 00:00:00

abstract：:1. We studied the effect of temporarily inhibiting neurons in the caudal fastigial nucleus in two rhesus macaques trained to make saccades to jumping targets. We placed injections of the gamma-aminobutyric acid (GABA) agonist muscimol unilaterally or bilaterally at sites in the caudal fastigial nucleus where we had re...

journal_title：Journal of neurophysiology

authors： Robinson FR,Straube A,Fuchs AF

更新日期：1993-11-01 00:00:00

abstract：:The response properties of ampullary electroreceptors of paddlefish, Polyodon spathula, were studied in vivo, as single-unit afferent responses to external electrical stimulation with varied intensities of several types of noise waveforms, all Gaussian and zero-mean. They included broadband white noise, Ornstein-Uhlen...

journal_title：Journal of neurophysiology

authors： Neiman AB,Yakusheva TA,Russell DF

更新日期：2007-11-01 00:00:00

abstract：:The rate and the total amount of Ca2+ elevation in the presynaptic terminals of bullfrog sympathetic ganglia depend on the firing frequency of the terminals. Carbonyl cyanide m-chlorophenylhydrazone (CCCP), a mitochondrial uncoupler, was used for testing whether mitochondrial Ca2+ uptake is one of the mechanisms that ...

journal_title：Journal of neurophysiology

authors： Peng YY

更新日期：1998-07-01 00:00:00

abstract：:Augmenting (or incremental) responses are progressively growing potentials elicited by 5- to 15-Hz stimulation within the thalamus, cerebral cortex, or by setting into action reciprocal thalamocortical neuronal loops. These responses are associated with short-term plasticity processes in thalamic and cortical neurons....

journal_title：Journal of neurophysiology

authors： Timofeev I,Steriade M

更新日期：1998-05-01 00:00:00