Abstract:
:CTP:phosphocholine cytidylyltransferase is the rate-controlling enzyme in phosphatidylcholine biosynthesis and is essential for the survival of eukaryotic cells. The murine cDNA for the cytidylyltransferase was cloned and sequenced. A genomic clone was isolated and the chromosomal location of the Ctpct locus determined by Southern blot hybridization of DNAs from a panel of interspecific backcross progeny derived from matings of [(C57BL/6J x Mus spretus)F1 x C57BL/6J] mice. These data place the Ctpct gene on mouse chromosome 16 between the Smst and Stf-1 genes.
journal_name
Genomicsjournal_title
Genomicsauthors
Rutherford MS,Rock CO,Jenkins NA,Gilbert DJ,Tessner TG,Copeland NG,Jackowski Sdoi
10.1016/s0888-7543(05)80377-5subject
Has Abstractpub_date
1993-12-01 00:00:00pages
698-701issue
3eissn
0888-7543issn
1089-8646pii
S0888-7543(05)80377-5journal_volume
18pub_type
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