Abstract:
:Physical maps can be constructed by "fingerprinting" a large number of random clones and inferring overlap between clones when the fingerprints are sufficiently similar. E. Lander and M. Waterman (Genomics 2: 231-239, 1988) gave a mathematical analysis of such mapping strategies. The analysis is useful for comparing various fingerprinting methods. Recently it has been proposed that ends of clones rather than the entire clone be fingerprinted or characterized. Such fingerprints, which include sequenced clone ends, require a mathematical analysis deeper than that of Lander-Waterman. This paper studies clone islands, which can include uncharacterized regions, and also the islands that are formed entirely from the ends of clones.
journal_name
Genomicsjournal_title
Genomicsauthors
Port E,Sun F,Martin D,Waterman MSdoi
10.1016/0888-7543(95)80086-2subject
Has Abstractpub_date
1995-03-01 00:00:00pages
84-100issue
1eissn
0888-7543issn
1089-8646pii
0888-7543(95)80086-2journal_volume
26pub_type
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