Abstract:
:Ciliary neurotrophic factor (CNTF) has recently been found to be important for the survival of motor neurons and has shown activity in animal models of amyotrophic lateral sclerosis (ALS). CNTF therefore holds promise as a treatment for ALS, and it and its receptor (CNTFR) are candidates for a gene involved in familial ALS. The CNTFR gene was mapped to chromosome 9 by PCR on a panel of human/CHO somatic cell hybrids and localized to 9p13 by PCR on a panel of radiation hybrids.
journal_name
Genomicsjournal_title
Genomicsauthors
Donaldson DH,Britt DE,Jones C,Jackson CL,Patterson Ddoi
10.1006/geno.1993.1409subject
Has Abstractpub_date
1993-09-01 00:00:00pages
782-4issue
3eissn
0888-7543issn
1089-8646pii
S0888-7543(83)71409-6journal_volume
17pub_type
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