Abstract：
:Cadmium (Cd) inhibited the activities of Na(+)-K+ ATPase (IC50 = 5.0 x 10(-5) M), K(+)-p-nitrophenyl phosphatase (PNPPase) (IC50 = 4.0 x 10(-5) M) and 3H-ouabain binding (IC50 = 7.5 x 10(-5) M) in rat brain microsomes. Monothiols (cysteine but not glutathione and D-penicillamine) and dithiols (dimercaprol, dimercaptosuccinic acid and dithiothreitol) offered varied levels of protection against Cd-inhibition of Na(+)-K+ ATPase. Protection of Na(+)-K+ ATPase by these sulfhydryl (SH) agents was higher at 7.5 as compared to 8.5 pH. The present data suggest that Cd-inhibited Na(+)-K+ ATPase, by interfering with phosphorylation of enzyme molecule and dephosphorylation of the enzyme-phosphoryl complex and exerts a similar effect to that of SH-blocking agents.
journal_name
Arch Environ Contam Toxicoljournal_title
Archives of environmental contamination and toxicologyauthors
Chetty CS,Cooper A,McNeil C,Rajanna Bdoi
10.1007/BF00212567subject
Has Abstractpub_date
1992-05-01 00:00:00pages
456-8issue
4eissn
0090-4341issn
1432-0703journal_volume
22pub_type
杂志文章abstract：:Cotton/polyester fabrics were contaminated with a 1.25% solution of methyl parathion (MeP) emulsifiable concentrate formulation, then laboratory laundered. The laundering variables were detergent type, concentration, water volume, and mechanical agitation. Specimens were unfinished (UN) and soil repellent finished (SR...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01160308
更新日期：1989-11-01 00:00:00
abstract：:Thirty-eight urban volunteers from the Lincoln and Omaha, Nebraska areas were monitored for carbaryl exposure during the summer of 1979. All volunteers were involved in the application of carbaryl incidental to their employment or leisure activities. The investigators made no attempt to affect the method of carbaryl a...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01055187
更新日期：1982-01-01 00:00:00
abstract：:A human breast cancer cell line (MCF-7) was used to develop an in vitro screening assay for the detection of xenoestrogenic environmental pollutants. MCF-7 cells were cultured in DMEM containing 5% fetal bovine serum (FBS). An estrogenic response was defined as an increase in the frequency of proliferating MCF-7 cells...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900322
更新日期：1998-04-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAH) have become an ubiquitous upper soil component as a consequence of industrialization involving a multitude of combustion processes. Ingestion of PAH contaminated soil is considered to be a major exposure route, specifically for small children living on these soils. Health risk as...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900259
更新日期：1997-10-01 00:00:00
abstract：:Carbaryl has been applied in Willapa Bay, Washington, for five decades to control burrowing shrimp (Neotrypaea californiensis and Upogebia pugettensis) on commercial oyster (Crassostrea gigas) beds. Concerns about effects on nontarget species, including fishes, have led to restrictions in use despite a lack of data on...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-013-9951-z
更新日期：2013-11-01 00:00:00
abstract：:The magnitude of between-strain differences in the sensitivity of algal species to toxicants is not well known. Yet, informations obtained with a single strain are used for ecotoxicological assessment and for interspecific comparisons. Using 12 strains, we determined whether intraspecific variability occurs in the gre...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900487
更新日期：1999-07-01 00:00:00
abstract：:Selenium and mercury were evaluated in muscle, liver, kidney, brain, and the stomach contents of juvenile scalloped hammerhead shark Sphyrna lewini. Se:Hg molar ratios were calculated. The average Hg levels in muscle ranged from 0.12 to 1.17 μg/g (wet weight); Hg was <0.39 μg/g in liver and kidneys and <0.19 μg/g in b...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-015-0226-8
更新日期：2015-11-01 00:00:00
abstract：:The concentrations of polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) were determined in soil samples taken from 24 sites in the vicinity of a municipal solid waste incinerator (Montcada, Barcelona, Spain). Samples were collected within a radius of 3 km in each of the three main direc...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900249
更新日期：1997-10-01 00:00:00
abstract：:The effects were determined of externally treating mallard (Anas platyrhynchos) eggs with two insecticides (lindane and toxaphene) and two herbicides (paraquat and 2,4,5-T) with formulations and concentrations similar to field applications. Paraquat was the most embryotoxic of the four compounds regardless of the type...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01055190
更新日期：1982-01-01 00:00:00
abstract：:The effects of short-term exposure (28 days) of free-feeding Limnonectus limnocharis (Indian cricket frog) tadpoles to field concentrations of malathion were investigated. This frog species is a major biotic component of the agroecosystems of the Western Ghats (13 degrees 18', 75 degrees 25' and 13 degrees 22', 75 deg...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-006-0015-5
更新日期：2007-02-01 00:00:00
abstract：:Despite that chironomids are the most widely used benthic insect test species worldwide, little research has been conducted so far with tropical chironomid representatives. This study was designed to evaluate the indigenous midge Chironomus sancticaroli as a candidate test species for use in tropical toxicity assessme...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-018-0575-1
更新日期：2019-01-01 00:00:00
abstract：:We determined dose-response curves for sublethal effects of the organophosphorus (OP) insecticide, chlorpyrifos, on bats. Big brown bats (Eptesicus fuscus, n = 64) were given a single dose of chlorpyrifos (nominal concentrations) of 0, 5, 10, 15, 20, 25, 30, or 60 µg/g body weight and examined at 12 or 24 h after dosi...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-016-0307-3
更新日期：2016-10-01 00:00:00
abstract：:We investigated mutagenicity, genotoxicity, and estrogenic activity in the porewaters of two river basins in southern Italy that had different features. Three samples from each site were collected in different seasons from 7 sites for a total of 21 samples. Mutagenicity was measured with the Ames test with and without...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-013-9928-y
更新日期：2013-10-01 00:00:00
abstract：:The effects of a 7-day exposure of 3-day-old wheat plantsto increasing Cd concentrations are described, with special attention beinggiven to chloroplast ultrastructural changes, chlorophyll fluorescenceresponses, chlorophyll and nutrient concentration changes as well as growthchanges of the whole plant. The plants tre...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900168
更新日期：1997-02-01 00:00:00
abstract：:Among the painters handling polyurethane varnish in two furniture manufacturing factories with high toluene diisocyanate (TDI) exposure (0.79 mg/m3 and 0.31 mg/m3), 26.3% and 15% subjects, respectively displayed asthmatic symptoms, lung function loss, and an increment in mast cell degranulation percentage specific to ...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01183884
更新日期：1991-11-01 00:00:00
abstract：:A total of 46 surface soil samples collected from the experimental area, buffer area, and core area of the Yellow River Delta Natural Reserve (YRDNR), China, and an adjacent area outside the reserve were analyzed for 23 PAHs including highly carcinogenic dibenzopyrene isomers. The total concentrations ranged from 87.2...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-014-0085-8
更新日期：2015-02-01 00:00:00
abstract：:It is widely recognized that marine mammals are exposed to a wide variety of pollutants, with a weight of evidence indicating impacts on their health. Since hundreds of new chemicals enter the global market every year,the methods, approaches and technologies used to characterize pollution levels or impacts are also in...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章,评审
doi：10.1007/s00244-015-0233-9
更新日期：2016-01-01 00:00:00
abstract：:The concentrations of the metals cadmium, copper, mercury, lead, silver, selenium and zinc were measured in the muscle and gonad tissues of five species of fish, yellowfin bream (Acanthopagrus australis), silverbiddy (Gerres subfasciatus) and trumpeter whiting (Sillago maculata), southern log finned goby (Favonigobiou...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-007-9027-z
更新日期：2008-02-01 00:00:00
abstract：:This study was aimed to assess the levels of selected heavy metals and pesticides in soil and plant products from an agricultural area of Belgrade, Serbia and to indicate possible sources and risks of contamination. Soil, vegetable, and fruit samples from the most important agricultural city areas were collected from ...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-009-9359-y
更新日期：2010-02-01 00:00:00
abstract：:A replicated field experiment was conducted at two locations to determine the disappearance of methomyl from flue-cured tobacco. Immediately after application, methomyl residues were 88 and 113 ppm at Clayton and 44 and 105 ppm at Reidsville, respectively, for 0.56 and 1.12 kg/ha application rates. After 5 days these ...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF02220903
更新日期：1977-01-01 00:00:00
abstract：:Artisanal and small-scale gold-mining activities performed in mountain areas of the Southern Ecuadorian Amazon have incorporated several heavy metals into the aquatic systems, thus increasing the risk of exposure in populations living in adjacent zones. Therefore, the objective of this study was to evaluate the contam...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-016-0285-5
更新日期：2016-08-01 00:00:00
abstract：:Cell-free extracts of fungal mycelia of two non-aflatoxigenic isolates of Aspergillus parasiticus (SRRC 163 and SRRC 2043) were examined for enzyme activities involved in the latter stages of aflatoxin biosynthesis. Post-microsomal fractions (105 Kxg supernatant) of both SRRC 163 (ATTC 56774) and SRRC 2043 were able t...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01062370
更新日期：1989-05-01 00:00:00
abstract：:A toxicity test for organophosphates (OP) and carbamates (C) was improved with the adult ragworm Nereis diversicolor. Animals were maintained in U-shaped glass tubes of 4-mm inner diameter fixed vertically on a plastic plate and placed in glass aquaria. Each tank was covered with glass in order to reduce evaporation a...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900244
更新日期：1997-08-01 00:00:00
abstract：:Embryos of fathead minnows were more resistant to phenol, 2,4-dimethylphenol (2,4-DMP), 2,4-dichlorophenol (2,4-DCP), and pentachlorophenol (PCP) than were larval or juvenile life stages. Growth of 28-day-old fish was the most sensitive indicator of stress during exposures to phenol, 2,4-DMP, and PCP, whereas survival...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF01055189
更新日期：1982-01-01 00:00:00
abstract：:Both in-field chemical investigation and in the laboratory toxic tests were carried out to systematically understand the pollution status of cadmium (Cd) and zinc (Zn) in Bohai Bay. Samples collected from surface seawater were determined to describe the distributions of Cd and Zn in Bohai Bay. The average values in ou...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-009-9461-1
更新日期：2010-07-01 00:00:00
abstract：:Methylmercury cation (MeHg) and divalent mercury (Hg++) accumulation in liver, kidney, and brain were quantified in prairie voles (Microtus ochrogaster) at 0, 3, 6, and 12 weeks during chronic exposure to aqueous MeHg. Dose groups received deionized water or aqueous solutions containing 9, 103, or 920 ng MeHg/ml. Our ...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-006-0006-6
更新日期：2007-04-01 00:00:00
abstract：:Chemical elimination rate constants (k2) were determined for 41 polychlorinated biphenyl (PCB) congeners in dosed freshwater mussels, Elliptio complanta, following a 150-day laboratory depuration period. Congener-specific elimination rates were inversely dependent on the n-octanol/water partition coefficient (K(ow)) o...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-004-2295-y
更新日期：2004-07-01 00:00:00
abstract：:Herons and egrets are ideal organisms to use asindicators of heavy metal exposure in an ecosystem because different speciesfeed at different levels of the food chain and live in both coastal andinland habitats. This paper reports on the concentration of heavy metals andselenium in the feathers of cattle egrets Bubulcu...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s002449900178
更新日期：1997-02-01 00:00:00
abstract：:Acute toxicity tests of selenium dioxide were conducted for 96 to 336 hr in intermittent-flow bioassay systems using six species of freshwater fish. The decreasing order of species sensitivity was: fathead minnow, flagfish, brook trout, channel catfish, goldfish, and bluegil. Curves relating median lethal concentratio...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/BF02221018
更新日期：1976-01-01 00:00:00
abstract：:Freshwater turtles (Chrysemys picta) were collected from two sites on Cape Cod, MA. One site (Moody Pond), adjacent to the Massachusetts Military Reservation (MMR), was considered potentially impacted by toxic agents deriving from contaminant point sources on the MMR. The second (reference) site (Washburn Pond), to th...
journal_title：Archives of environmental contamination and toxicology
pub_type： 杂志文章
doi：10.1007/s00244-003-0246-7
更新日期：2005-02-01 00:00:00
