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Comparative bioavailability of two different rectal preparations of piroxicam in man.

Abstract：

:A comparative pharmacokinetic study was performed with two types of suppository each containing 20 mg piroxicam. The bioavailability of piroxicam was studied in 24 healthy volunteers in a double blind, randomised, cross over study. No significant difference was found in the pharmacokinetic parameters [AUC(0-72 h), AUC, Cmax, t1/2 beta] calculated from plasma concentration time curves, indicating that the two preparations were bioequivalent.

journal_name

Eur J Clin Pharmacol

journal_title

European journal of clinical pharmacology

authors

Benkö S,Grézal G,Nagy E,Klebovich I

doi

10.1007/BF02333031

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

315-7

issue

3

eissn

0031-6970

issn

1432-1041

journal_volume

43

pub_type

临床试验,杂志文章,随机对照试验

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