Apocrine adenocarcinoma arising in Moll gland cystadenoma.

Abstract:

CASE REPORT:An 85-year-old woman had a bluish tumor medially on the margin of the left upper eyelid. Malignant melanoma of the conjunctiva was presumed; the lesion was excised and submitted for routine histopathologic examination. There are no signs of recurrence or metastatic disease after follow-up for 1 year. METHODS:Light microscopy with routine and histochemical stains were used for diagnosis. Immunohistochemical analysis included the use of a broad-spectrum "cocktail" of cytokeratin antibodies (AE1/AE3). RESULTS:The features were those of a cystic cavity lined with apocrine epithelium in one part infiltrating the wall and consistent with an apocrine adenocarcinoma derived from a Moll gland cystadenoma. CONCLUSION:Malignant Moll gland tumors are extremely uncommon but may be confused with conjunctival malignant melanoma or metastatic disease. The differential diagnosis to other sweat gland tumors such as eccrine adenocarcinoma and benign apocrine tumor or to sebaceous carcinoma can be difficult.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Seregard S

doi

10.1016/s0161-6420(93)31412-0

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

1716-9

issue

11

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(93)31412-0

journal_volume

100

pub_type

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