Abstract:
BACKGROUND AND OBJECTIVES:The purpose of this paper is to evaluate the utility of positron emission tomography (PET) with fluorine-18-labeled fluoro-deoxyglucose (FDG) in the preoperative differential diagnosis of gallbladder tumors. We performed PET studies of gallbladder tumors in order to predict the malignancy of these tumors preoperatively. METHODS:Sixteen patients who had protuberant lesions in the gallbladder and who were scheduled to undergo surgery were studied with PET using FDG. Focally increased FDG uptake in the gallbladder region was considered malignant. The FDG-PET findings were compared with the histological findings of surgical pathology. RESULTS:Sensitivity of FDG-PET was 75% (6/8 patients). One of two false-negative cases suffered from diabetes mellitus, and in the other case, the lesion was small. Specificity was 87.5% (7/8 patients). A case with xanthogranulomatous cholecystitis (XGC) was the only false-positive case. CONCLUSIONS:FDG-PET may be able to provide important information for evaluating the malignancy of gallbladder tumors.
journal_name
J Surg Oncoljournal_title
Journal of surgical oncologyauthors
Koh T,Taniguchi H,Yamaguchi A,Kunishima S,Yamagishi Hdoi
10.1002/jso.10295subject
Has Abstractpub_date
2003-10-01 00:00:00pages
74-81issue
2eissn
0022-4790issn
1096-9098journal_volume
84pub_type
杂志文章abstract::A study was carried out to determine the interrelationship between the inhalation of nitrogen dioxide (0.4 +/- 0.50 ppm), lung metastases development from circulating cancer cells, and death rate from such metastases. C57 BL/6J mice were used in these experiments. Animals were divided into control and NO2-exposed grou...
journal_title:Journal of surgical oncology
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