Differential diagnosis of gallbladder cancer using positron emission tomography with fluorine-18-labeled fluoro-deoxyglucose (FDG-PET).

Abstract:

BACKGROUND AND OBJECTIVES:The purpose of this paper is to evaluate the utility of positron emission tomography (PET) with fluorine-18-labeled fluoro-deoxyglucose (FDG) in the preoperative differential diagnosis of gallbladder tumors. We performed PET studies of gallbladder tumors in order to predict the malignancy of these tumors preoperatively. METHODS:Sixteen patients who had protuberant lesions in the gallbladder and who were scheduled to undergo surgery were studied with PET using FDG. Focally increased FDG uptake in the gallbladder region was considered malignant. The FDG-PET findings were compared with the histological findings of surgical pathology. RESULTS:Sensitivity of FDG-PET was 75% (6/8 patients). One of two false-negative cases suffered from diabetes mellitus, and in the other case, the lesion was small. Specificity was 87.5% (7/8 patients). A case with xanthogranulomatous cholecystitis (XGC) was the only false-positive case. CONCLUSIONS:FDG-PET may be able to provide important information for evaluating the malignancy of gallbladder tumors.

journal_name

J Surg Oncol

authors

Koh T,Taniguchi H,Yamaguchi A,Kunishima S,Yamagishi H

doi

10.1002/jso.10295

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

74-81

issue

2

eissn

0022-4790

issn

1096-9098

journal_volume

84

pub_type

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