HTLV-II seroprevalence in pygmies across Africa since 1970.

abstract：:Serological studies on 926 blood samples from 703 Brazilian Kayapo (Cayapo) Indians showed, by conventional definition of HTLV seropositivity, a 28% prevalence of human T lymphotropic virus (HTLV) infection, the highest yet reported. Immunoblot (WB) and SYNTH-EIA patterns indicate that the predominant infecting agent ...

journal_title：AIDS research and human retroviruses

authors： Black FL,Biggar RJ,Neel JV,Maloney EM,Waters DJ

更新日期：1994-09-01 00:00:00

abstract：:Here we report the construction, sequencing, and biological characterization of a molecular clone of HIV-1(92UG001), a virus representative of subtype D strains circulating in Uganda. The virus produced by the clone has an aggressive syncytium-inducing phenotype, which matches that of the parental virus. This phenotyp...

journal_title：AIDS research and human retroviruses

authors： Novelli P,Vella C,Oxford J,Daniels RS

更新日期：2002-01-01 00:00:00

abstract：:The development of HIV vaccines is an urgent priority and there is need to generate reagents representing multiple subtypes that can be used to screen HIV-1-specific responses. We used Aldrithiol-2 (AT-2), a mild oxidizing reagent, to eliminate the infectivity of HIV while maintaining its structure and ability to be p...

journal_title：AIDS research and human retroviruses

authors： Rutebemberwa A,Bess JW Jr,Brown B,Arroyo M,Eller M,Slike B,Polonis V,McCutchan F,Currier JR,Birx D,Robb M,Marovich M,Lifson JD,Cox JH

更新日期：2007-04-01 00:00:00

abstract：:Peripheral blood mononuclear cell (PBMC) cultures were established from patients with antibody to human immunodeficiency virus (HIV). Asymptomatically infected patients [5 of 19] had significant lymphocyte transformation responses induced in culture by a purified, recombinant envelope glycoprotein (rgp120) from the vi...

journal_title：AIDS research and human retroviruses

authors： Torseth JW,Berman PW,Merigan TC

更新日期：1988-02-01 00:00:00

abstract：:Before the introduction of HAART, HIV-associated neurocognitive impairment (NCI) was recognized as an independent risk factor for death. Since 1996, we conducted a prospective study to assess whether NCI still represents a negative prognostic factor for mortality. Patients were administered measures of neurocognitive ...

journal_title：AIDS research and human retroviruses

authors： Tozzi V,Balestra P,Serraino D,Bellagamba R,Corpolongo A,Piselli P,Lorenzini P,Visco-Comandini U,Vlassi C,Quartuccio ME,Giulianelli M,Noto P,Galgani S,Ippolito G,Antinori A,Narciso P

更新日期：2005-08-01 00:00:00

abstract：:Interleukin-15 (IL-15) enhances the effector mechanisms of anti-HIV immune responses and thus is considered a potential adjuvant of HIV-1 vaccine. However, there are a lack of data concerning the relationships between IL-15 expression and regulation in HIV-1-infected patients and the course of disease progression. We ...

journal_title：AIDS research and human retroviruses

authors： Tarkowski M,Ferraris L,Martone S,Strambio de Castillia F,Misciagna D,Mazzucchelli RI,Lattuada E,Paraninfo G,Galli M,Riva A,Elvis Study Group.

更新日期：2012-07-01 00:00:00

abstract：:The Brazilian AIDS epidemic is characterized by significant geographic contrasts: a reduction in incidence and mortality in the epicenter (southeast) and an increase in the northeast. HIV-1-transmitted drug resistance (TDR) and genetic diversity were investigated among 106 antiretroviral (ARV)-naive patients from Mara...

journal_title：AIDS research and human retroviruses

authors： Moura ME,Reis MN,Lima YA,Eulálio KD,Cardoso LP,Stefani MM

更新日期：2015-02-01 00:00:00

abstract：:Mutations within the protease gene associated with reduced susceptibility to protease inhibitors have been well documented for HIV-1 group M subtype B strains. In contrast, limited genotypic and phenotypic information is available for the genetically diverse HIV-1 group O strains. Preexisting resistance-associated pol...

journal_title：AIDS research and human retroviruses

authors： Luk KC,Kaptué L,Zekeng L,Soriano V,Gürtler L,Devare SG,Schochetman G,Hackett J Jr

更新日期：2001-11-01 00:00:00

abstract：:Ascorbic acid (ascorbate or vitamin C) has been shown to suppress the induction of HIV in latently infected T lymphocytic cells following stimulation with a tumor promoter (PMA) and inflammatory cytokine (TNF-alpha). To assess whether this inhibition was mediated via modulation of the cellular transcription factor, NF...

journal_title：AIDS research and human retroviruses

authors： Harakeh S,Jariwalla RJ

更新日期：1997-02-10 00:00:00

abstract：:The World Health Organizations HIV Drug Resistance (WHO HIVDR) Threshold survey method was used to assess transmitted HIVDR in newly diagnosed HIV-1-infected primigravida women attending the Prevention of Parent to Child Transmission (PPTCT) centers in Kakinada, in whom it is likely that the infection had recently occ...

journal_title：AIDS research and human retroviruses

authors： Thorat SR,Chaturbhuj DN,Hingankar NK,Chandrasekhar V,Koppada R,Datkar SR,Srikantiah P,Garg R,Kabra S,Haldar P,Reddy DC,Bachani D,Tripathy SP,Paranjape RS

更新日期：2011-12-01 00:00:00

abstract：:Murine monoclonal antibodies (MAbs) raised against a recombinant nef protein fragment of human immunodeficiency virus type 1 (HIV-1) strain BH10 were characterized by an epitope mapping system using overlapping decapeptides. Four different immunogenic regions were identified. Ten human HIV-1-positive sera were tested ...

journal_title：AIDS research and human retroviruses

authors： Schneider T,Harthus HP,Hildebrandt P,Niedrig M,Bröker M,Weigelt W,Beck A,Pauli G

更新日期：1991-01-01 00:00:00

abstract：:The purpose of this study was to investigate the mechanism of acquired cellular resistance to AZT, a mechanism that has been described as a potential source of drug resistance in addition to viral mutations. To study this phenomenon the kinetics parameters of thymidine kinase (TK) activity have been defined in CEMazt,...

journal_title：AIDS research and human retroviruses

authors： Antonelli G,Turriziani O,Verri A,Narciso P,Ferri F,D'Offizi G,Dianzani F

更新日期：1996-02-10 00:00:00

abstract：:The humoral immune response is a mechanism that potently suppresses or prevents viral infections. However, genetic diversity and resistance to antibody-mediated neutralization are serious obstacles in controlling HIV-1 infection. In this study, we isolated monoclonal antibodies from an SIV-infected macaque by using th...

journal_title：AIDS research and human retroviruses

authors： Kuwata T,Katsumata Y,Takaki K,Miura T,Igarashi T

更新日期：2011-05-01 00:00:00

abstract：:The chemokine polymorphisms CXCR6-3E/K, In1.1T/C, H7 haplotype, CX(3)CR1-V249I, and CX(3)CR1-T280M have been shown to affect the course of HIV infection. We studied their influence on immunologic and virologic response to HAART in a group of 143 HIV-1 patients. We performed Kaplan-Meier analysis using the following en...

journal_title：AIDS research and human retroviruses

authors： Passam AM,Sourvinos G,Krambovitis E,Miyakis S,Stavrianeas N,Zagoreos I,Spandidos DA

更新日期：2007-08-01 00:00:00

abstract：:HIV-1 disease is associated with many infectious and neoplastic complications. This is particularly true of the genitourinary tract, where high rates of renal disease, neoplasms, voiding and erectile dysfunction, hematuria, opportunistic genitourinary infections, and epididymo-orchitis are found in HIV-1-infected indi...

journal_title：AIDS research and human retroviruses

authors： Coburn M

更新日期：1998-04-01 00:00:00

abstract：:Susceptibility to HIV infection was examined in macrophages differentiated from human monocytes by macrophage colony-stimulating factor (M-CSF) or granulocyte/macrophage colony-stimulating factor (GM-CSF). The replication of macrophage-tropic human immunodeficiency virus type-1 (HIV-1), which was determined by reverse...

journal_title：AIDS research and human retroviruses

authors： Matsuda S,Akagawa K,Honda M,Yokota Y,Takebe Y,Takemori T

更新日期：1995-09-01 00:00:00

abstract：:HIV-1 group N (HIV-1/N) remains rare and mainly restricted to Cameroon. In this study, we report a new HIV-1/N infected case identified during routine HIV screening activities in Yaounde. The genetic characterization of the near full-length genome of this virus strain revealed that it is genetically distinct to all HI...

journal_title：AIDS research and human retroviruses

authors： Tagnouokam Ngoupo PA,Sadeuh-Mba SA,De Oliveira F,Ngo-Malabo ET,Ngono L,Plantier JC,Kfutwah A,Njouom R

更新日期：2018-07-01 00:00:00

abstract：:Retroviruses have been suggested as possible pathogenic factors in multiple sclerosis (MS), supported by the observation that endogenous retroviruses are activated in MS patients. Different members of the herpes family of which several are neurotropic have also been suggested as factors in MS pathogenesis. Further, in...

journal_title：AIDS research and human retroviruses

authors： Brudek T,Christensen T,Hansen HJ,Bobecka J,Møller-Larsen A

更新日期：2004-04-01 00:00:00

abstract：:Given the rising HIV incidence in men who have sex with men (MSM) despite repeatedly proven effectiveness of oral HIV pre-exposure prophylaxis, behaviorally congruent periodic dosing strategies, such as dosing microbicides as lubricants, are now in demand. Rectal microbicide gel studies largely administer gels using v...

journal_title：AIDS research and human retroviruses

authors： Shieh EC,Weld ED,Fuchs EJ,Hiruy H,Buckheit KW,Buckheit RW Jr,Breakey J,Hendrix CW

更新日期：2017-08-01 00:00:00

abstract：:Transmitted drug resistance mutations (TDRM) have been a constant threat to treatment efficacy. We evaluated TDRM in plasma RNA of 217 antiretroviral therapy-naive patients from sites in the São Paulo metropolitan area, collected from 2012 to 2014. The partial HIV-1 polymerase region was sequenced using Big Dye termin...

journal_title：AIDS research and human retroviruses

authors： Guimarães PM,Ferreira JL,Coelho LP,Cavalcanti Jde S,Lopes GI,Matsuda EM,Almeida FJ,Almeida VC,Campeas AE,Junior LC,Brígido LF,Sa˜o Paulo Salvage Workgroup.

更新日期：2015-12-01 00:00:00

abstract：:The surface envelope glycoprotein gp46 of the human T cell leukemia virus type 1 elicits a strong immune response. Its protective role against HTLV-1 infection in animal models is well established, suggesting that recombinant envelope glycoproteins or synthetic peptides could be used as an effective vaccine. However, ...

journal_title：AIDS research and human retroviruses

authors： Tallet B,Astier-Gin T,Moynet D,Londos-Gagliardi D,Guillemain B

更新日期：2001-03-01 00:00:00

abstract：:Eight HIV-2-infected Caucasian men living in the same geographical area in Gipuzkoa (northern Spain) have been identified in the last 5 years. HIV-2 infection in this area is uncommon, and no other cases of HIV-2 infection have been found after extensive testing for HIV-1/2 antibodies. Epidemiological data suggested a...

journal_title：AIDS research and human retroviruses

authors： Cilla G,Rodés B,Pérez-Trallero E,Arrizabalaga J,Soriano V

更新日期：2001-03-20 00:00:00

abstract：:The Matilda effect illustrates how the contributions of women to science have been historically attributed to their male colleagues in some circumstances. This effect may perpetuate and even increase the gender gap we currently face. Recognizing the work of great women who led our way and committed their careers to tr...

journal_title：AIDS research and human retroviruses

authors： Izquierdo-Useros N

更新日期：2018-09-01 00:00:00

abstract：:Despite repeated exposures to HIV-1, some individuals remain seronegative. This study reports that sera from a fraction of exposed seronegative (ESN) subjects showed HIV-neutralizing activity; 5 of 17 ESN sera and none of 17 controls neutralized two different HIV-1 primary isolates (range of neutralizing titers: 1/20 ...

journal_title：AIDS research and human retroviruses

authors： Lopalco L,Pastori C,Cosma A,Burastero SE,Capiluppi B,Boeri E,Beretta A,Lazzarin A,Siccardi AG

更新日期：2000-01-20 00:00:00

abstract：:We evaluated the performance of T-SPOT.TB (a commercial interferon gamma release assay) and its accuracy for the diagnosis of active tuberculosis (TB) among HIV-infected subjects with advanced immunodeficiency. In a clinical prospective study, we assessed the performance of T-SPOT.TB for the diagnosis of active TB in ...

journal_title：AIDS research and human retroviruses

authors： Chen J,Sun J,Zhang R,Liu L,Zheng Y,Shen Y,Wang Z,Sun F,Li L,Lu H

更新日期：2011-03-01 00:00:00

abstract：:We studied the phylogeny of HIV-1 subtype F viruses from children and adults in Romania in order to (1) clarify whether the Romanian subtype F epidemic was caused by one or several virus introductions and (2) gain insight into the route of spread of the HIV-1 subtype F virus among children and adults in Romania. env (...

journal_title：AIDS research and human retroviruses

authors： Op De Coul E,van den Burg R,Asjö B,Goudsmit J,Cupsa A,Pascu R,Usein C,Cornelissen M

更新日期：2000-03-01 00:00:00

abstract：:Patients with HIV-1 and human T-lymphotropic virus type 2 (HTLV-2) coinfections often exhibit a clinical course similar to that seen in HIV-1-infected individuals who are long-term nonprogressors. These findings have been attributed in part to the ability of HTLV-2 to activate production of antiviral chemokines and to...

journal_title：AIDS research and human retroviruses

authors： Barrios CS,Castillo L,Giam CZ,Wu L,Beilke MA

更新日期：2013-07-01 00:00:00

abstract：:The presence of human immunodeficiency virus (HIV)-specific antibodies was examined in plasma and cervicovaginal (mucosal) samples of 24 HIV-exposed uninfected (EU) female sexual partners of HIV-infected men, and compared with findings in 18 HIV-infected and 15 low-risk HIV-uninfected women. Only HIV-infected women ha...

journal_title：AIDS research and human retroviruses

authors： Buchacz K,Parekh BS,Padian NS,van der Straten A,Phillips S,Jonte J,Holmberg SD

更新日期：2001-12-10 00:00:00

abstract：:Elderly people living with HIV are increasing. At present in the United States, nearly half of newly diagnosed HIV-infected people are aged >50 years. Diagnosis and treatment of HIV-infected elderly patients tends to be delayed by several health care factors as several life-threatening diseases are common in elderly p...

journal_title：AIDS research and human retroviruses

authors： Bhatta M,Nandi S,Dutta N,Dutta S,Saha MK

更新日期：2020-06-01 00:00:00

abstract：:Stavudine (d4T) has been associated with lipoatrophy and hyperlactatemia. In recent studies, d4T has also been related to both hypercholesterolemia and hypertriglyceridemia. Replacing d4T with another nucleoside analogue such as abacavir (ABC) may reduce lactate levels and improve lipoatrophy in the long term. However...

journal_title：AIDS research and human retroviruses

authors： García-Benayas T,Blanco F,Alcolea A,Cruz JJ,González-Lahoz J,Soriano V

更新日期：2004-12-01 00:00:00