Abstract:
:Resistance to linezolid among Enterococcus faecium and Enterococcus faecalis isolates has been reported in patients who receive a prolonged course of the drug. We report two cases of linezolid-resistant Enterococcus faecalis that occurred in patients who previously received linezolid for infections with vancomycin-resistant Enterococcus faecium. Both isolates had the G2576U mutation in the 23S rRNA previously reported in isolates of Enterococcus faecium. The number of gene copies mutated in the 23S rRNA correlated with the level of resistance.
journal_name
Diagn Microbiol Infect Disjournal_title
Diagnostic microbiology and infectious diseaseauthors
Ruggero KA,Schroeder LK,Schreckenberger PC,Mankin AS,Quinn JPdoi
10.1016/s0732-8893(03)00153-6subject
Has Abstractpub_date
2003-11-01 00:00:00pages
511-3issue
3eissn
0732-8893issn
1879-0070pii
S0732889303001536journal_volume
47pub_type
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