A mathematical model for elongation of a peptide chain.

abstract：:The human body's immune response to bacterial challenge, even when successful in controlling the infection, can result in negative consequences for the host, including reduced functionality of associated tissues. We present and analyze a low-dimensional mathematical model of this immune response to pathogen invasion, ...

journal_title：Bulletin of mathematical biology

authors： Caudill L,Lynch F

更新日期：2018-08-01 00:00:00

abstract：:Recent discoveries in ecological stoichiometry have indicated that food quality in terms of the phosphorus/carbon (P/C) ratio affects consumers whether the imbalance involves insufficient or excess nutrients. This phenomenon is called the "stoichiometric P/C knife-edge." In this study, we develop and analyze a produce...

journal_title：Bulletin of mathematical biology

authors： Asik L,Kulik J,Long KR,Peace A

更新日期：2019-07-01 00:00:00

abstract：:The comprehension of activities and functions of complex brain structures requires, among other things, information on simultaneous activities in several regions. Results reported in the literature using multi(micro/macro)electrode recordings or imaging techniques provide incomplete information due either to the small...

journal_title：Bulletin of mathematical biology

authors： Ventriglia F

更新日期：1998-03-01 00:00:00

abstract：:A kinetic model is proposed to delineate the factors that determine the coronary reactive hyperemic response (RHR) to transient ischemia. The model comprises of myocardial-interstitial (M) and vascular (V) compartments. Vasodilator metabolites (VM) are produced in the M compartment during the interval of coronary occl...

journal_title：Bulletin of mathematical biology

authors： Wong AY

更新日期：1995-01-01 00:00:00

abstract：:A staged-progression HIV model is formulated and used to investigate the potential impact of an imperfect vaccine. The vaccine is assumed to have several desirable characteristics such as protecting against infection, causing bypass of the primary infection stage, and offering a disease-altering therapeutic effect (so...

journal_title：Bulletin of mathematical biology

authors： Gumel AB,McCluskey CC,van den Driessche P

更新日期：2006-11-01 00:00:00

abstract：:We incorporate a vector-bias term into a malaria-transmission model to account for the greater attractiveness of infectious humans to mosquitoes in terms of differing probabilities that a mosquito arriving at a human at random picks that human depending on whether he is infectious or susceptible. We prove that transcr...

journal_title：Bulletin of mathematical biology

authors： Chamchod F,Britton NF

更新日期：2011-03-01 00:00:00

abstract：:It has been recently observed that the dynamical properties of mass action systems arising from many models of biochemical reaction networks can be characterized by considering the corresponding properties of a related generalized mass action system. The correspondence process known as network translation in particula...

journal_title：Bulletin of mathematical biology

authors： Johnston MD

更新日期：2015-06-01 00:00:00

abstract：:The mutation process is introduced into the colored coalescent theory. The mutation process can be viewed as an independent Poisson process running on the colored genealogical random tree generated by the colored coalescent process, with the edge lengths of the random tree serving as the time scale for the mutation pr...

journal_title：Bulletin of mathematical biology

authors： Tian JP,Lin XS

更新日期：2009-11-01 00:00:00

abstract：:Developing a quantitative science of sustainability requires bridging mathematical concepts from fields contributing to sustainability science. The concept of substitutability is central to sustainability but is defined differently by different fields. Specifically, economics tends to define substitutability as a marg...

journal_title：Bulletin of mathematical biology

authors： Fenichel EP,Zhao J

更新日期：2015-02-01 00:00:00

abstract：:The surface protein B7-H1, also called PD-L1 and CD274, is found on carcinomas of the lung, ovary, colon, and melanomas but not on most normal tissues. B7-H1 has been experimentally determined to be an antiapoptotic receptor on cancer cells, where B7-H1-positive cancer cells have been shown to be immune resistant, and...

journal_title：Bulletin of mathematical biology

authors： Galante A,Tamada K,Levy D

更新日期：2012-01-01 00:00:00

abstract：:Direct reciprocity is a chief mechanism of mutual cooperation in social dilemma. Agents cooperate if future interactions with the same opponents are highly likely. Direct reciprocity has been explored mostly by evolutionary game theory based on natural selection. Our daily experience tells, however, that real social a...

journal_title：Bulletin of mathematical biology

authors： Masuda N,Ohtsuki H

更新日期：2009-11-01 00:00:00

abstract：:One of the main challenges in systems biology is the establishment of the metabolome: a catalogue of the metabolites and biochemical reactions present in a specific organism. Current knowledge of biochemical pathways as stored in public databases such as KEGG, is based on carefully curated genomic evidence for the pre...

journal_title：Bulletin of mathematical biology

authors： Félix L,Rosselló F,Valiente G

更新日期：2009-04-01 00:00:00

abstract：:Advances in fluorescent labeling of cells as measured by flow cytometry have allowed for quantitative studies of proliferating populations of cells. The investigations (Luzyanina et al. in J. Math. Biol. 54:57-89, 2007; J. Math. Biol., 2009; Theor. Biol. Med. Model. 4:1-26, 2007) contain a mathematical model with fluo...

journal_title：Bulletin of mathematical biology

authors： Banks HT,Sutton KL,Thompson WC,Bocharov G,Roose D,Schenkel T,Meyerhans A

更新日期：2011-01-01 00:00:00

abstract：:The culmination of the morphogenesis of the cellular slime mould Dictyostelium discoideum involves complex cell movements which transform a mound of cells into a globule of spores on a slender stalk. We show that cyclic AMP signalling and differential adhesion, combined with cell differentiation and slime production, ...

journal_title：Bulletin of mathematical biology

authors： Marée AF,Hogeweg P

更新日期：2002-03-01 00:00:00

abstract：:The apoptotic caspase-3/8 feedback loop describes the core of the extrinsic pro-apoptotic signaling pathway, an essential part of apoptosis. Latter is a prototype of the programmed cell death, which enables organisms to remove damaged or infected cells. The reaction network of the caspase-3/8 feedback loop in a single...

journal_title：Bulletin of mathematical biology

authors： Daub M

更新日期：2013-11-01 00:00:00

abstract：:A model, based on the principles of continuum mechanics, is presented for the analysis of cell-velocity fields within wool follicles. The model requires specification of three follicle characteristics in the form of spatially varying fields: viscosity, cell density and cell production rate. The viscosity is introduced...

journal_title：Bulletin of mathematical biology

authors： Louie K,Hall AJ,Gandar PW

更新日期：1998-01-01 00:00:00

abstract：:Many dynamic programming algorithms consist of a 'forward pass' computation to optimize a cost function, followed by a 'choice recovery' computation to construct a configuration that optimizes the cost function. 'Checkpointing' is a method to perform choice recovery using limited storage. During a forward pass, checkp...

journal_title：Bulletin of mathematical biology

authors： Bax E

更新日期：2005-07-01 00:00:00

abstract：:Human T-cell lymphotropic virus type I (HTLV-I) infection in humans causes a chronic infection of CD4+ T cells, and is associated with various disease outcomes, among them with the development of adult T-cell leukemia (ATL). The T-cell dynamics after HTLV-I infection can be described in a mathematical model with coupl...

journal_title：Bulletin of mathematical biology

authors： Stilianakis NI,Seydel J

更新日期：1999-09-01 00:00:00

abstract：:The lactose operon in Escherichia coli was the first known gene regulatory network, and it is frequently used as a prototype for new modeling paradigms. Historically, many of these modeling frameworks use differential equations. More recently, Stigler and Veliz-Cuba proposed a Boolean model that captures the bistabili...

journal_title：Bulletin of mathematical biology

authors： Jenkins A,Macauley M

更新日期：2017-08-01 00:00:00

abstract：:We develop an age-structured ODE model to investigate the role of intermittent preventive treatment (IPT) in averting malaria-induced mortality in children, and its related cost in promoting the spread of antimalarial drug resistance. IPT, a malaria control strategy in which a full curative dose of an antimalarial med...

journal_title：Bulletin of mathematical biology

authors： Manore CA,Teboh-Ewungkem MI,Prosper O,Peace A,Gurski K,Feng Z

更新日期：2019-01-01 00:00:00

abstract：:This study investigates fluid flow and elastic deformation in tissues that are drained by the primary lymphatic system. A model is formulated based on the Rossi hypothesis that states that the primary lymphatic valves, which are formed by overlapping endothelial cells around the circumferential lining of lymphatic cap...

journal_title：Bulletin of mathematical biology

authors： Heppell C,Roose T,Richardson G

更新日期：2015-06-01 00:00:00

abstract：:Premised on relatively simple assumptions, mathematical models like those of Monod, Pirt or Droop inadequately explain the complex transient behavior of microbial populations. In particular, these models fail to explain many aspects of the dynamics of a Tetrahymena pyriformis-Escherichia coli community. In this study ...

journal_title：Bulletin of mathematical biology

authors： Jaworska JS,Hallam TG,Schultz TW

更新日期：1996-03-01 00:00:00

abstract：:In previous studies, we used a mathematical model of the thick ascending limb (TAL) to investigate nonlinearities in the tubuloglomerular feedback (TGF) loop. That model does not represent other segments of the nephron, the water, and NaCl transport along which may impact fluid flow rate and NaCl transport along the T...

journal_title：Bulletin of mathematical biology

authors： Layton AT,Edwards A

更新日期：2010-01-01 00:00:00

abstract：:To investigate morphogenesis and in particular circularization mechanisms in young mycelia, we observe cultures of the zygomycete Mucor spinosus and develop discrete models of two-dimensional filamental branching growth. The models are based on the hypothesis that the fungus secretes a regulatory substance that diffus...

journal_title：Bulletin of mathematical biology

authors： Indermitte C,Liebling M,Clémençon H

更新日期：1994-07-01 00:00:00

abstract：:A dynamic model for cell differentiation, where cells with internal chemical reaction dynamics interact with each other and replicate was studied. It led to spontaneous differentiation of cells and determination, as discussed in the isologous diversification. The following features of the differentiation were obtained...

journal_title：Bulletin of mathematical biology

authors： Furusawa C,Kaneko K

更新日期：1998-07-01 00:00:00

abstract：:The Hodgkin and Huxley equations have served as the benchmark model in electrophysiology since 1950s. But it suffers from four major drawbacks. Firstly, it is only phenomenological not mechanistic. Secondly, it fails to exhibit the all-or-nothing firing mechanism for action potential generation. Thirdly, it lacks a th...

journal_title：Bulletin of mathematical biology

authors： Deng B

更新日期：2017-06-01 00:00:00

abstract：:Population management using artificial gene drives (alleles biasing inheritance, increasing their own transmission to offspring) is becoming a realistic possibility with the development of CRISPR-Cas genetic engineering. A gene drive may, however, have to be stopped. "Antidotes" (brakes) have been suggested, but have ...

journal_title：Bulletin of mathematical biology

authors： Girardin L,Calvez V,Débarre F

更新日期：2019-12-01 00:00:00

abstract：:This study is concerned with reconciling theoretical modelling of the fluid flow in the airway surface liquid with experimental visualisation of tracer transport in human airway epithelial cultures. The airways are covered by a dense mat of cilia of length approximately 6 microm beating in a watery periciliary liquid ...

journal_title：Bulletin of mathematical biology

authors： Smith DJ,Gaffney EA,Blake JR

更新日期：2007-04-01 00:00:00

abstract：:Cholera is an acute gastro-intestinal infection that affects millions of people throughout the world each year, primarily but not exclusively in developing countries. Because of its public health ramifications, considerable mathematical attention has been paid to the disease. Here we consider one neglected aspect of c...

journal_title：Bulletin of mathematical biology

authors： Kobe J,Pritchard N,Short Z,Erovenko IV,Rychtář J,Rowell JT

更新日期：2018-10-01 00:00:00

abstract：:Although cell migration is an essential process in development, how cells reach their final destination is not well understood. Secreted molecules are known to have a migratory effect, but it remains unclear whether such molecules act as directional guidance cues or as motility regulators. There is potential to use si...

journal_title：Bulletin of mathematical biology

authors： Cai AQ,Landman KA,Hughes BD

更新日期：2006-01-01 00:00:00