Abstract：
:Cholera is an acute gastro-intestinal infection that affects millions of people throughout the world each year, primarily but not exclusively in developing countries. Because of its public health ramifications, considerable mathematical attention has been paid to the disease. Here we consider one neglected aspect of combating cholera: personal participation in anti-cholera interventions. We construct a game-theoretic model of cholera in which individuals choose whether to participate in either vaccination or clean water consumption programs under assumed costs. We find that relying upon individual compliance significantly lowers the incidence of the disease as long as the cost of intervention is sufficiently low, but does not eliminate it. The relative costs of the measures determined whether a population preferentially adopts a single preventative measure or employs the measure with the strongest early adoption.
journal_name
Bull Math Bioljournal_title
Bulletin of mathematical biologyauthors
Kobe J,Pritchard N,Short Z,Erovenko IV,Rychtář J,Rowell JTdoi
10.1007/s11538-018-0476-5subject
Has Abstractpub_date
2018-10-01 00:00:00pages
2580-2599issue
10eissn
0092-8240issn
1522-9602pii
10.1007/s11538-018-0476-5journal_volume
80pub_type
杂志文章abstract：:We introduce here a gene evolution model which is an extension of the time-continuous stochastic IDIS model (Lèbre and Michel in J. Comput. Biol. Chem. 34:259-267, 2010) to sequence length. This new IDISL (Insertion Deletion Independent of Substitution based on sequence Length) model gives an analytical expression of ...
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