Familial chronic lymphocytic leukemia. Immunologic and cellular characterization.

abstract：BACKGROUND:Memphis and Shelby County, Tennessee, experienced an epidemic of hepatitis A in 1994 and 1995. More than 1700 cases were reported. OBJECTIVE:To characterize the clinical features of patients hospitalized during a large urban epidemic of hepatitis A. DESIGN:Retrospective chart review. SETTING:15 acute care...

journal_title：Annals of internal medicine

authors： Willner IR,Uhl MD,Howard SC,Williams EQ,Riely CA,Waters B

更新日期：1998-01-15 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV) may cause viral antigenemia, detected primarily as p24 viral core protein. Among 16 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex studied serially, 12 had or developed antigenemia ranging from 16 to 3006 pg/mL in plasma. The level ...

journal_title：Annals of internal medicine

authors： Jackson GG,Paul DA,Falk LA,Rubenis M,Despotes JC,Mack D,Knigge M,Emeson EE

更新日期：1988-02-01 00:00:00

abstract：:We examined the survival time and costs of therapy for patients with end-stage renal disease. A computer simulation model of the current system was constructed to estimate the cost-effectiveness of home and center hemodialysis and live related as well as cadaver donor renal transplantation. Analysis of the simulation ...

journal_title：Annals of internal medicine

authors： Roberts SD,Maxwell DR,Gross TL

更新日期：1980-02-01 00:00:00

abstract：:Very low calorie diets used to treat moderate and severe obesity produce average weight losses of 20 kg in 12 weeks. This paper reviews the development of very low calorie diets from research on fasting in the late 1950s and examines data on the amount of dietary protein needed to achieve positive nitrogen balance. Th...

journal_title：Annals of internal medicine

authors： Wadden TA,Stunkard AJ,Brownell KD

更新日期：1983-11-01 00:00:00

abstract：:In 1978 the Institute of Medicine issued "A Manpower Policy for Health Care," the report of a study of major issues bearing on the availability of an adequate number of physicians for provision of primary care and on potential strategies for an appropriate manpower policy. The report was analyzed by committees of the ...

journal_title：Annals of internal medicine

authors： Peterson ML

更新日期：1980-06-01 00:00:00

abstract：:As the third decade since AIDS was first recognized comes to an end, extraordinary advances have occurred in the understanding, treatment, and prevention of HIV infection and AIDS. As a result of these successes, it is now time to focus on future challenges. Paramount among these is reaching the goal of truly controll...

journal_title：Annals of internal medicine

authors： Dieffenbach CW,Fauci AS

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Optimal management of patients who are clinically suspected of having ventilator-associated pneumonia remains open to debate. OBJECTIVE:To evaluate the effect on clinical outcome and antibiotic use of two strategies to diagnose ventilator-associated pneumonia and select initial treatment for this condition....

journal_title：Annals of internal medicine

authors： Fagon JY,Chastre J,Wolff M,Gervais C,Parer-Aubas S,Stéphan F,Similowski T,Mercat A,Diehl JL,Sollet JP,Tenaillon A

更新日期：2000-04-18 00:00:00

abstract：BACKGROUND:The established International Prognostic Index for lymphomas has not included patients with systemic AIDS-related non-Hodgkin lymphoma. OBJECTIVE:To establish the most appropriate prognostic index for use in patients with systemic AIDS-related non-Hodgkin lymphoma. DESIGN:A prospective study involving univ...

journal_title：Annals of internal medicine

authors： Bower M,Gazzard B,Mandalia S,Newsom-Davis T,Thirlwell C,Dhillon T,Young AM,Powles T,Gaya A,Nelson M,Stebbing J

更新日期：2005-08-16 00:00:00

abstract：OBJECTIVE:To describe the diagnostic difficulties, response to therapy, and clinical features of lymphomatoid papulosis and the cumulative frequency of transformation to lymphoma. DESIGN:Case series. SETTING:University hospitals. METHODS:The records of 21 patients with lymphomatoid papulosis who were seen from 1986 ...

journal_title：Annals of internal medicine

authors： Cabanillas F,Armitage J,Pugh WC,Weisenburger D,Duvic M

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Physical activity has been related to enhanced bone mass and improved physical functioning and thus may reduce the risk for osteoporotic fracture. OBJECTIVE:To determine whether higher levels of physical activity are related to lower incidence of hip, wrist, and vertebral fractures. DESIGN:Prospective coho...

journal_title：Annals of internal medicine

authors： Gregg EW,Cauley JA,Seeley DG,Ensrud KE,Bauer DC

更新日期：1998-07-15 00:00:00

abstract：:The U.S. Preventive Services Task Force (USPSTF) seeks to provide reliable and accurate evidence-based recommendations to primary care clinicians. However, clinicians indicate frustration with the lack of guidance provided by the USPSTF when the evidence is insufficient to make a recommendation. This article describes...

journal_title：Annals of internal medicine

authors： Petitti DB,Teutsch SM,Barton MB,Sawaya GF,Ockene JK,DeWitt T,U.S. Preventive Services Task Force.

更新日期：2009-02-03 00:00:00

abstract：:Neuroblastoma, the second commonest solid tumor in children, is a neoplasm of the peripheral autonomic nervous system that usually occurs before children are 6 years old. Therapy of localized tumor (clinical stage I and II) and of a special form of metastatic tumor (clinical stage IV-S) is usually successful, but trea...

journal_title：Annals of internal medicine

authors： Seeger RC,Siegel SE,Sidell N

更新日期：1982-12-01 00:00:00

abstract：Background:High-risk human papillomavirus (hrHPV) testing to triage women with minor cervical lesions generates many referrals. Purpose:To evaluate the accuracy of genotyping for HPV types 16 and 18 and its utility as a second triage step after hrHPV testing in women with minor cervical lesions. Data Sources:Searches...

journal_title：Annals of internal medicine

authors： Arbyn M,Xu L,Verdoodt F,Cuzick J,Szarewski A,Belinson JL,Wentzensen N,Gage JC,Khan MJ

更新日期：2017-01-17 00:00:00

abstract：:Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine. All patients had previous mucocutaneous reactions to chrysotherapy. Manifestations included pleurisy in five of six patients, rashes in three, nephritis in two, and neurologic disturbances...

journal_title：Annals of internal medicine

authors： Chalmers A,Thompson D,Stein HE,Reid G,Patterson AC

更新日期：1982-11-01 00:00:00

abstract：:To determine the relative sensitivity and specificity of noninvasive methods for detecting aortic insufficiency, we compared the accuracy of auscultation, echocardiography, and pulsed Doppler echocardiography in detecting aortic insufficiency in 106 patients in whom the presence or absence of the lesion was shown by s...

journal_title：Annals of internal medicine

authors： Grayburn PA,Smith MD,Handshoe R,Friedman BJ,DeMaria AN

更新日期：1986-05-01 00:00:00

abstract：:Twenty-three patients with hyperparathyroidism from six families with the multiple endocrine adenomatosis (MEA) I-syndrome were tested by secretin provocation. In nine cases this led to increases in serum gastrin ranging from 298 to 13 300 pg/ml, whereas the maximum rise in gastrin in the other 14 patients was 32 pg/m...

journal_title：Annals of internal medicine

authors： Lamers CB,Buis JT,van Tongeren J

更新日期：1977-06-01 00:00:00

abstract：:In the 5 years since its release for clinical use, acyclovir (9-[2-hydroxyethoxymethyl]guanine) has proved to be a safe and effective agent for therapy of herpes simplex and varicella-zoster infections. The drug's availability in topical, oral, and intravenous preparations has allowed its use in a range of clinical si...

journal_title：Annals of internal medicine

authors： Dorsky DI,Crumpacker CS

更新日期：1987-12-01 00:00:00

abstract：:In addition to gonorrhea and syphilis, both of which may develop primarily at anorectal or pharyngeal sites, a number of conditions, including Neisseria meningitidis urethritis, nonspecific urethritis, anorectal herpes, condyloma acuminatum, amebiasis, giardiasis, shigellosis, typhoid fever, enterobiasis, and hepatiti...

journal_title：Annals of internal medicine

authors： Owen WF Jr

更新日期：1980-06-01 00:00:00

abstract：:During 1973 and 1974, we looked for cases of Colorado tick fever throughout Colorado; 228 cases were identified. Although 90% of the patients reported exposure to ticks before illness, only 52% were aware of an actual tick bite. Typical symptoms of fever, myalgia, and headache were common, but gastrointestinal symptom...

journal_title：Annals of internal medicine

authors： Goodpasture HC,Poland JD,Francy DB,Bowen GS,Horn KA

更新日期：1978-03-01 00:00:00

abstract：:Disorders determined wholly or in part by genetic factors constitute a substantial number of human diseases. This realization has grown during the past 2 decades with the recognition of many specific heritable conditions and the identification of familial risk factors for common disorders. New technologies, such as fe...

journal_title：Annals of internal medicine

authors： Shapiro LJ,Comings DE,Jones OW,Rimoin DL

更新日期：1986-04-01 00:00:00

abstract：:The efficacy of corticosteroid treatment in the prophylaxis of the fat embolism syndrome was evaluated in a prospective, randomized, double-blind study of high-risk patients with long-bone fractures. Using a set of objective diagnostic criteria, we saw a significant difference in the incidence of the syndrome between ...

journal_title：Annals of internal medicine

authors： Schonfeld SA,Ploysongsang Y,DiLisio R,Crissman JD,Miller E,Hammerschmidt DE,Jacob HS

更新日期：1983-10-01 00:00:00

abstract：:A 42-year-old woman developed goitrous hypothyroidism while receiving ethionamide for treatment of an atypical mycobacterial infection. Five weeks after discontinuation of ethionamide therapy, thyroid function had returned to normal. The goitrogenic effect was studied in vitro by incubating ethionamide in various conc...

journal_title：Annals of internal medicine

authors： Drucker D,Eggo MC,Salit IE,Burrow GN

更新日期：1984-06-01 00:00:00

abstract：STUDY OBJECTIVE:To compare single-dose and 10-day treatment regimens of trimethoprim-sulfamethoxazole in women with acute dysuria, urgency, or urinary frequency. DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:Student health center at a major university. PATIENTS:Consecutive sample of 255 young wo...

journal_title：Annals of internal medicine

authors： Fihn SD,Johnson C,Roberts PL,Running K,Stamm WE

更新日期：1988-03-01 00:00:00

abstract：:Restrictive cardiomyopathy produced by primary cardiac amyloidosis may have a clinical syndrome identical to noncalcific constrictive pericarditis. We report two patients with amyloidosis and restrictive physiology who had enlarged papillary muscles shown on left ventricular angiocardiogram. Rapid volume expansion wit...

journal_title：Annals of internal medicine

authors： Maule WF,Martin RH

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Screening can detect prostate cancer at earlier, asymptomatic stages, when treatments might be more effective. PURPOSE:To update the 2002 and 2008 U.S. Preventive Services Task Force evidence reviews on screening and treatments for prostate cancer. DATA SOURCES:MEDLINE (2002 to July 2011) and the Cochrane ...

journal_title：Annals of internal medicine

authors： Chou R,Croswell JM,Dana T,Bougatsos C,Blazina I,Fu R,Gleitsmann K,Koenig HC,Lam C,Maltz A,Rugge JB,Lin K

更新日期：2011-12-06 00:00:00

abstract：:Important historical changes have occurred both in the content of the periodic health examination and in the legitimacy with which this examination has been viewed. These changes reflect fundamental shifts in the objectives of the examination and in the concerns of its advocates, the most prominent of whom have been p...

journal_title：Annals of internal medicine

authors： Han PK

更新日期：1997-11-15 00:00:00

abstract：:The coverage, cost, and quality problems of the U.S. health care system are evident. Sustainable health care reform must go beyond financing expanded access to care to substantially changing the organization and delivery of care. The FRESH-Thinking Project (www.fresh-thinking.org) held a series of workshops during whi...

journal_title：Annals of internal medicine

authors： Arrow K,Auerbach A,Bertko J,Brownlee S,Casalino LP,Cooper J,Crosson FJ,Enthoven A,Falcone E,Feldman RC,Fuchs VR,Garber AM,Gold MR,Goldman D,Hadfield GK,Hall MA,Horwitz RI,Hooven M,Jacobson PD,Jost TS,Kotlikoff LJ

更新日期：2009-04-07 00:00:00

abstract：STUDY OBJECTIVE:To test the hypothesis that work as a respiratory therapist is associated with an increased risk of developing asthma. DESIGN:Cross-sectional questionnaire study comparing respiratory therapists with controls (physical therapists and radiologic technologists). Subsequent validation of reported asthma w...

journal_title：Annals of internal medicine

authors： Kern DG,Frumkin H

更新日期：1989-05-15 00:00:00

abstract：PURPOSE:To review methods of preventing or minimizing the adverse effects associated with the transfusion of passenger leukocytes present in cellular blood components and to define groups of patients who are at risk for adverse effects. DATA SOURCES:English-language articles on transfusion medicine. STUDY SELECTION:O...

journal_title：Annals of internal medicine

authors： Lane TA,Anderson KC,Goodnough LT,Kurtz S,Moroff G,Pisciotto PT,Sayers M,Silberstein LE

更新日期：1992-07-15 00:00:00

abstract：:Hepatitis is a significant complication of the treatment of hemophilia A with factor VIII concentrates. Chronic liver disease in these patients is infrequently documented in the literature. The results of percutaneous liver biopsy, under the coverage of glycine-precipitated factor VIII, in six patients with hemophilia...

journal_title：Annals of internal medicine

authors： Lesesne HR,Morgan JE,Blatt PM,Webster WP,Roberts HR

更新日期：1977-06-01 00:00:00