Ethionamide-induced goitrous hypothyroidism.

abstract：BACKGROUND:Women treated with therapeutic chest radiation may develop breast cancer. PURPOSE:To summarize breast cancer risk and breast cancer surveillance in women after chest radiation for pediatric or young adult cancer. DATA SOURCES:Studies from MEDLINE, EMBASE, the Cochrane Library, and CINAHL (1966 to December ...

journal_title：Annals of internal medicine

authors： Henderson TO,Amsterdam A,Bhatia S,Hudson MM,Meadows AT,Neglia JP,Diller LR,Constine LS,Smith RA,Mahoney MC,Morris EA,Montgomery LL,Landier W,Smith SM,Robison LL,Oeffinger KC

更新日期：2010-04-06 00:00:00

abstract：OBJECTIVE:To determine the most effective and safe dose of enoxaparin to prevent deep venous thrombosis in high-risk surgical patients. DESIGN:A double-blind, randomized, multicenter clinical trial. SETTING:Private, university, and government hospitals in the United States. PATIENTS:572 patients having elective hip ...

journal_title：Annals of internal medicine

authors： Spiro TE,Johnson GJ,Christie MJ,Lyons RM,MacFarlane DE,Blasier RB,Tremaine MD

更新日期：1994-07-15 00:00:00

abstract：:Platelets may have a role in the development of animal tumor metastases. Ultrastructural studies in vivo have shown arrested tumor emboli surrounded by platelets. Several tumor cell lines induce thrombocytopenia in vivo. Certain tumor cells aggregate platelets in vitro. Correlations exist between the ability of some t...

journal_title：Annals of internal medicine

authors： Karpatkin S,Pearlstein E

更新日期：1981-11-01 00:00:00

abstract：:The diagnostic and therapeutic value of the angiotensin converting enzyme inhibitor teprotide (SQ 20881) was assessed in 18 patients with hypertensive emergencies. Mean blood pressure fell 31 +/- 18 mm Hg in the 10 subjects who responded to 1 mg/kg body weight administered intravenously, whereas it fell 5 +/- 3 mm Hg ...

journal_title：Annals of internal medicine

authors： Tifft CP,Gavras H,Kershaw GR,Gavras I,Brunner HR,Liang CS,Chobanian AV

更新日期：1979-01-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the efficacy and toxicity of cyclosporin A in patients with severe, treatment-refractory rheumatoid arthritis. DESIGN:Prospective randomized, double-blind 6-month trial. PATIENTS:Thirty-one patients who had classic seropositive rheumatoid arthritis with active synovitis unresponsive to conve...

journal_title：Annals of internal medicine

authors： Yocum DE,Klippel JH,Wilder RL,Gerber NL,Austin HA 3rd,Wahl SM,Lesko L,Minor JR,Preuss HG,Yarboro C

更新日期：1988-12-01 00:00:00

abstract：:Physician performance failures are not rare and pose substantial threats to patient welfare and safety. Few hospitals respond to such failures promptly or effectively. Failure to ensure the quality and safety of the performance of colleagues is a breach of medicine's fiduciary responsibility to the public. A major rea...

journal_title：Annals of internal medicine

authors： Leape LL,Fromson JA

更新日期：2006-01-17 00:00:00

abstract：BACKGROUND:The high prevalence of classic cardiac risk factors in patients with non-insulin-dependent diabetes mellitus does not explain the increased cardiovascular-related morbidity and mortality in these patients. Fibrinogen may have a role in this excess risk. OBJECTIVE:To evaluate the following in patients with n...

journal_title：Annals of internal medicine

authors： Bruno G,Cavallo-Perin P,Bargero G,Borra M,D'Errico N,Pagano G

更新日期：1996-10-15 00:00:00

abstract：:In alternative medicine, the main question regarding placebo has been whether a given therapy has more than a placebo effect. Just as mainstream medicine ignores the clinical significance of its own placebo effect, the placebo effect of unconventional medicine is disregarded except for polemics. This essay looks at th...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-06-04 00:00:00

abstract：:Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia. The first step in the diagnostic approach to all patients with venous thrombosis consists of a careful history and physical examin...

journal_title：Annals of internal medicine

authors： Bauer KA

更新日期：2001-09-04 00:00:00

abstract：BACKGROUND:Screening for hereditary hemochromatosis is traditionally done by using serum iron studies. However, mutation analysis of the hemochromatosis-associated HFE gene has recently become available. OBJECTIVE:To compare the cost-effectiveness of no screening with four screening strategies that incorporate HFE gen...

journal_title：Annals of internal medicine

authors： El-Serag HB,Inadomi JM,Kowdley KV

更新日期：2000-02-15 00:00:00

abstract：Background:Acute pancreatitis (AP) varies in severity, prompting development of systems aimed at predicting prognosis to help guide therapy. Although several prediction approaches are available, their test characteristics and clinical utility are not completely understood. Purpose:To evaluate the test characteristics ...

journal_title：Annals of internal medicine

authors： Di MY,Liu H,Yang ZY,Bonis PA,Tang JL,Lau J

更新日期：2016-10-04 00:00:00

abstract：:Streptococcus pneumoniae causes substantial morbidity and mortality. Incidence and severity are increased among populations with some chronic diseases. The currently available polyvalent polysaccharide vaccine induces antibody production among immunologically competent recipients against the 14 serotypes responsible f...

journal_title：Annals of internal medicine

authors： Schwartz JS

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:Pharmaceutical companies and other trial sponsors must submit certain trial results to ClinicalTrials.gov. The validity of these results is unclear. PURPOSE:To validate results posted on ClinicalTrials.gov against publicly available U.S. Food and Drug Administration (FDA) reviews on Drugs@FDA. DATA SOURCES...

journal_title：Annals of internal medicine

authors： Schwartz LM,Woloshin S,Zheng E,Tse T,Zarin DA

更新日期：2016-09-20 00:00:00

abstract：Background:Biosimilars are of growing clinical, regulatory, and commercial importance. Purpose:To summarize evidence about the bioequivalence between biosimilar and reference tumor necrosis factor-α (TNF-α) inhibitors. Data Sources:PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and LILACS from incept...

journal_title：Annals of internal medicine

authors： Chingcuanco F,Segal JB,Kim SC,Alexander GC

更新日期：2016-10-18 00:00:00

abstract：:Much time and effort are spent on designing primary research studies. Similar care must be given to planning systematic reviews. The review should be based on an important, well-focused question that is relevant to patient care. By formulating the question properly, the criteria that primary studies must meet to be in...

journal_title：Annals of internal medicine

authors： Counsell C

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha is present in arteries in giant cell arteritis. OBJECTIVE:To evaluate the efficacy of infliximab, an anti-tumor necrosis factor-alpha agent, in giant cell arteritis. DESIGN:Randomized, controlled trial. SETTING:22 sites in the United States, the United Kingdom, Belgium, Italy, ...

journal_title：Annals of internal medicine

authors： Hoffman GS,Cid MC,Rendt-Zagar KE,Merkel PA,Weyand CM,Stone JH,Salvarani C,Xu W,Visvanathan S,Rahman MU,Infliximab-GCA Study Group.

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The magnitude, consistency, and manner of association between sedentary time and outcomes independent of physical activity remain unclear. PURPOSE:To quantify the association between sedentary time and hospitalizations, all-cause mortality, cardiovascular disease, diabetes, and cancer in adults independent ...

journal_title：Annals of internal medicine

authors： Biswas A,Oh PI,Faulkner GE,Bajaj RR,Silver MA,Mitchell MS,Alter DA

更新日期：2015-01-20 00:00:00

abstract：:It is hypothesized that peritoneal fluid might be used as an alternative vehicle for monitoring the clinical chemistry of patients on peritoneal dialyses and save these patients the venesection and resultant blood loss. Peritoneal fluid was obtained before 47.2% of 106 dialysis treatments and compared with simultaneou...

journal_title：Annals of internal medicine

authors： Kelton JG,Ulan R,Stiller C,Holmes E

更新日期：1978-07-01 00:00:00

abstract：:A retrospective analysis of the course of systemic lupus erythematosus in pregnant patients hospitalized at UCLA during a 15-year period provided important prognostic information. Women with systemic lupus erythematosus became pregnant if renal function was reasonably well preserved. Pregnancy infrequently posed a ser...

journal_title：Annals of internal medicine

authors：

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Common diseases, particularly dementia, have large social costs for the U.S. population. However, less is known about the end-of-life costs of specific diseases and the associated financial risk for individual households. OBJECTIVE:To examine social costs and financial risks faced by Medicare beneficiaries ...

journal_title：Annals of internal medicine

authors： Kelley AS,McGarry K,Gorges R,Skinner JS

更新日期：2015-11-17 00:00:00

abstract：BACKGROUND:The Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 global treatment target aims to achieve 73% virologic suppression among HIV-infected persons worldwide by 2020. OBJECTIVE:To estimate the clinical and economic value of reaching this ambitious goal in South Africa, by using a microsimulation m...

journal_title：Annals of internal medicine

authors： Walensky RP,Borre ED,Bekker LG,Resch SC,Hyle EP,Wood R,Weinstein MC,Ciaranello AL,Freedberg KA,Paltiel AD

更新日期：2016-09-06 00:00:00

abstract：:The competition for funds to conduct clinical research is intense, and only a minority of grant proposals receive funding. In particular, funding for patient-oriented research lags behind that allocated for basic science research. Grant writing is a skill of fundamental importance to the clinical researcher, and condu...

journal_title：Annals of internal medicine

authors： Inouye SK,Fiellin DA

更新日期：2005-02-15 00:00:00

abstract：:Transitional care has been defined as a set of actions designed to ensure the coordination and continuity of health care as patients transfer between different locations or different levels of care in the same location. Transitional care, which primarily concerns the relatively brief time interval that begins with pre...

journal_title：Annals of internal medicine

authors： Coleman EA,Berenson RA

更新日期：2004-10-05 00:00:00

abstract：:The safety of using inhaled beclomethasone dipropionate for the treatment of severe asthma during pregnancy was evaluated during 45 pregnancies in 40 women. Despite chronic administration of theophylline and, in some women, ephedrine, the asthma was so severe that corticosteroids were essential to prevent emergency ro...

journal_title：Annals of internal medicine

authors： Greenberger PA,Patterson R

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. DESIGN:Retrospective cohort analysis of compu...

journal_title：Annals of internal medicine

authors： Macpherson DS,Snow R,Lofgren RP

更新日期：1990-12-15 00:00:00

abstract：:We performed immunohistopathologic studies on biopsied lung tissue obtained from two patients with lupus pneumonitis using immunofluorescence, immunoperoxidase, electron microscopy, and acid-microelution. In both patients, immunofluorescence showed granular deposits of IgG, the third component of complement (C3), and ...

journal_title：Annals of internal medicine

authors： Inoue T,Kanayama Y,Ohe A,Kato N,Horiguchi T,Ishii M,Shiota K

更新日期：1979-07-01 00:00:00

abstract：:Forty patients with systemic lupus erythematosus randomly received inactivated bivalent (A/NJ and A/Victoria) influenza vaccine or saline in a double-blind study. During 20 weeks of follow-up, no deterioration in major organ function or increase in disease flares was observed in the immunized group as compared with th...

journal_title：Annals of internal medicine

authors： Williams GW,Steinberg AD,Reinertsen JL,Klassen LW,Decker JL,Dolin R

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Impressive decreases in cardiovascular mortality have been achieved through risk factor reduction and clinical intervention, yet cardiovascular disease remains a leading cause of death nationally. OBJECTIVE:To estimate up-to-date preventable fractions of cardiovascular mortality associated with elimination ...

journal_title：Annals of internal medicine

authors： Patel SA,Winkel M,Ali MK,Narayan KM,Mehta NK

更新日期：2015-08-18 00:00:00

abstract：:In five patients with hypertension and marked impairment of renal function due to renal artery stenosis in a solitary functioning kidney, a nonsurgical technique, percutaneous transluminal angioplasty, was used to dilate the stenotic renal artery. Blood pressure improved in all five patients, and renal function improv...

journal_title：Annals of internal medicine

authors： Weinberger MH,Yune HY,Grim CE,Luft FC,Klatte EC,Donohue JP

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Screening can detect prostate cancer at earlier, asymptomatic stages, when treatments might be more effective. PURPOSE:To update the 2002 and 2008 U.S. Preventive Services Task Force evidence reviews on screening and treatments for prostate cancer. DATA SOURCES:MEDLINE (2002 to July 2011) and the Cochrane ...

journal_title：Annals of internal medicine

authors： Chou R,Croswell JM,Dana T,Bougatsos C,Blazina I,Fu R,Gleitsmann K,Koenig HC,Lam C,Maltz A,Rugge JB,Lin K

更新日期：2011-12-06 00:00:00