Extracorporeal immunoadsorption for the specific removal of lipoprotein (a) (Lp(a) apheresis): preliminary clinical data.

abstract：:Various hydrophobic benzenediacetic esters, the corresponding benzenedipropionic esters, and branched alkyl esters were intercalated into DMPC liposomes, where the molar ratio (n/n) of ester:DMPC was 1:5. In the case of the very long-chain derivatives, double carbonyl peaks were observed in the 13C NMR spectrum. This ...

journal_title：Chemistry and physics of lipids

authors： Cohen Y,Afri M,Frimer AA

更新日期：2008-10-01 00:00:00

abstract：:Isoprostanes (IsoPs) are a complex family of compounds produced, in vivo, from peroxidation of polyunsaturated fatty acids (AA, DHA, EPA, alpha-linolenic) via a free-radical-catalyzed mechanism. Carbocyclic annulations are extremely important reactions and the stereocontrolled intramolecular free-radical cyclization h...

journal_title：Chemistry and physics of lipids

authors： Durand T,Guy A,Henry O,Roland A,Bernad S,El Fangour S,Vidal JP,Rossi JC

更新日期：2004-03-01 00:00:00

abstract：:The objective of this work was to examine the interaction of cholesterol with both phosphatidylcholines, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) or 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), and sphingomyelins, N-oleoyl-D-sphingomyelin (O-SPM) or N-palmitoyl-D-sphingomyelin (P-SPM), in monolay...

journal_title：Chemistry and physics of lipids

authors： Mattjus P,Slotte JP

更新日期：1996-06-17 00:00:00

abstract：:The 13C- and 31P-NMR spectra and DSC thermograms of unsonicated dispersions consisting of phospholipids of varying methylation stages of the propanolamine head group were investigated. Methylation of the head group was accompanied by a corresponding reduction in the phase transition temperatures. In the liquid crystal...

journal_title：Chemistry and physics of lipids

authors： Gawrisch K,Arnold K,Rüger HJ,Kertscher P,Nuhn P

更新日期：1977-12-01 00:00:00

abstract：:Some thermodynamic and structural aspects of propranolol-DPPC liposomes interaction were investigated by DSC and X-ray diffraction: the lamellar arrangement of the lipid matrix remains intact even at high concentrations of the drug (until 1:1 drug/lipid molar ratio). However, the bilayer thickness increases significan...

journal_title：Chemistry and physics of lipids

authors： Albertini G,Donati C,Phadke RS,Ponzi Bossi MG,Rustichelli F

更新日期：1990-09-01 00:00:00

abstract：:Seven members of the methyl-6-O-(n-acyl)-α-D-glucopyranosides have been synthesised and their transitional properties determined. The undecanoyl and octadecanoyl members do not exhibit liquid crystallinity while the members having chain lengths between dodecanoyl and hexadecanoyl exhibit a monotropic smectic A phase. ...

journal_title：Chemistry and physics of lipids

authors： Cook AG,Wardell JL,Imrie CT

更新日期：2011-02-01 00:00:00

abstract：:Chain-ordering/melting transition in a series of saturated diacylphosphatidylcholines (PCs) in aqueous dispersions have been studied experimentally (calorimetric and ultrasonic techniques) and theoretically (an Ising-like lattice model). The shape of the calorimetric curves was compared with the theoretical data and i...

journal_title：Chemistry and physics of lipids

authors： Kharakoz DP,Panchelyuga MS,Tiktopulo EI,Shlyapnikova EA

更新日期：2007-12-01 00:00:00

abstract：:Cardiolipins (CLs) are ancient and unusual dimeric phospholipids localized in the plasma membrane of bacteria and in the inner mitochondrial membrane of eukaryotes. In mitochondria, two types of asymmetries--trans-membrane and molecular--are essential determinants of CL functions. In this review, we describe CL-based ...

journal_title：Chemistry and physics of lipids

authors： Kagan VE,Chu CT,Tyurina YY,Cheikhi A,Bayir H

更新日期：2014-04-01 00:00:00

abstract：:2-N-(Hexadecanoyl)-amino-4-nitrophenyl phosphorylcholine-hydroxide a compound resembling sphingomyelin is synthesized. It is cleaved by sphingomyelinase to the chromogenic N-acylaminonitrophenyl moiety. Phospholipase C preparations do not hydrolyze this compound. The starting material is 2-amino-4-nitrophenol which wh...

journal_title：Chemistry and physics of lipids

authors： Gal AE,Fash FJ

更新日期：1976-02-01 00:00:00

abstract：:The interaction of the amphoteric surfactant N-dodecyl-N,N-dimethylbetaine (C12-Bet) with phosphatidylcholine (PC) liposomes was investigated. Permeability alterations were detected as a change in 5(6)-carboxyfluorescein (CF) released from the interior of vesicles and bilayer solubilization as a decrease in the static...

journal_title：Chemistry and physics of lipids

authors： de la Maza A,Lopez O,Coderch L,Parra JL

更新日期：1998-07-01 00:00:00

abstract：:The role of membrane cholesterol as a crucial regulator in the structure and function of membrane proteins and receptors is well documented. However, there is a lack of consensus on the mechanism for such regulation. We have previously shown that the function of an important neuronal receptor, the serotonin1A receptor...

journal_title：Chemistry and physics of lipids

authors： Pal S,Chakraborty H,Bandari S,Yahioglu G,Suhling K,Chattopadhyay A

更新日期：2016-03-01 00:00:00

abstract：:Bile acids directly related to liver and intestinal function are used as indicators of hepatobiliary and intestinal diseases. Here, we have designed and realized a capillary sensory platform for the detection of bile acids using liquid crystals (LCs). LC droplets confined in micro-capillaries are homeotropically align...

journal_title：Chemistry and physics of lipids

authors： Kim HJ,Jang CH

更新日期：2017-04-01 00:00:00

abstract：:Surface plasmon resonance (SPR) has become one of the most important techniques for studying macromolecular interactions. The most obvious advantages of SPR over other techniques are: direct and rapid determination of association and dissociation rates of binding process, no need for labelling of protein or lipids, an...

journal_title：Chemistry and physics of lipids

authors： Besenicar M,Macek P,Lakey JH,Anderluh G

更新日期：2006-06-01 00:00:00

abstract：:The gel-like liquid phase transition of dimyristoylphosphatidylcholine (DMPC) large unilamellar vesicles prepared by reverse phase evaporation has been investigated in buffers containing ethanol by quasi-elastic light scattering (QLS) and vibrational (infrared and Raman) spectroscopy. With the QLS technique, the relat...

journal_title：Chemistry and physics of lipids

authors： Hantz E,Cao A,Taillandier E

更新日期：1988-12-01 00:00:00

abstract：:The influence of the temperature on the adsorption of monomeric and micellar solutions of the anionic surfactant sodium dodecyl sulfate (SDS) on phosphatidylcholine (PC) liposomes was investigated using the fluorescent probe 2-(p-toluidinyl)-naphthalene-6-sodium sulfonate (TNS). The number of adsorbed molecules was qu...

journal_title：Chemistry and physics of lipids

authors： Cócera M,López O,Estelrich J,Parra JL,de la Maza A

更新日期：2003-06-01 00:00:00

abstract：:Applications of solid-state NMR spectroscopy for investigating the influences of lipid-cholesterol interactions on membrane fluctuations are reviewed in this paper. Emphasis is placed on understanding the energy landscapes and fluctuations at an emergent atomistic level. Solid-state (2)H NMR spectroscopy directly meas...

journal_title：Chemistry and physics of lipids

authors： Molugu TR,Brown MF

更新日期：2016-09-01 00:00:00

abstract：:Interaction of a cationic phenazinium dye, phenosafranin (PSF), with the anionic liposomal vesicle/bilayer of dimyristoyl-L-alpha-phosphatidylglycerol (DMPG) has been demonstrated using steady state and time resolved fluorescence and fluorescence anisotropy techniques. The charge transfer emission spectrum of PSF show...

journal_title：Chemistry and physics of lipids

authors： Bose D,Ghosh D,Das P,Girigoswami A,Sarkar D,Chattopadhyay N

更新日期：2010-01-01 00:00:00

abstract：:Cardiolipins (CLs) are important biologically for their unique role in biomembranes that couple phosphorylation and electron transport like bacterial plasma membranes, chromatophores, chloroplasts and mitochondria. CLs are often tightly coupled to proteins involved in oxidative phosphorylation. The first step in under...

journal_title：Chemistry and physics of lipids

authors： Boscia AL,Treece BW,Mohammadyani D,Klein-Seetharaman J,Braun AR,Wassenaar TA,Klösgen B,Tristram-Nagle S

更新日期：2014-02-01 00:00:00

abstract：:In this report we have investigated the differences in the uptake and metabolization of exogenous GM1 by human fibroblasts, as a function of its supramolecular organization in solution. For this we used a tritium labelled GM1, given alone or inserted in dispersions of phosphatidylcholine (PC) or sulphatide. The additi...

journal_title：Chemistry and physics of lipids

authors： Giglioni A,Chigorno V,Pitto M,Valsecchi M,Palestini P,Ghidoni R

更新日期：1990-08-01 00:00:00

abstract：:Ceriporiopsis subvermispora is a selective white-rot fungus that secretes alk(en)ylitaconic acids named ceriporic acids, known as ion redox silencers. In this study, we analysed a series of extracellular lipid-related metabolites produced by the fungus and found that a wide variety of ceriporic acids and fatty acids, ...

journal_title：Chemistry and physics of lipids

authors： Nishimura H,Murayama K,Watanabe T,Honda Y,Watanabe T

更新日期：2012-01-01 00:00:00

abstract：:The stimulatory, cytostatic and cytotoxic effects of polyunsaturated fatty acids, prostaglandins, thromboxanes, hydroperoxy fatty acids, hydroxy fatty acids and leukotrienes on normal and tumor cells are described. Their effects are related to the ability of the cells to undergo lipid peroxidation. The significance of...

journal_title：Chemistry and physics of lipids

authors： Bégin ME

更新日期：1987-11-01 00:00:00

abstract：:Lamellar structures of intercellular lipids in stratum corneum of hairless mouse were studied at various water contents by small-angle X-ray diffraction. At room temperature there are at least two lamellar structures, long and short lamellar structures, with repeat distances of 13.6 and around 6 nm, respectively. The ...

journal_title：Chemistry and physics of lipids

authors： Ohta N,Ban S,Tanaka H,Nakata S,Hatta I

更新日期：2003-03-01 00:00:00

abstract：:The development of "molecular rulers" would allow one to quantitatively locate the penetration depth of intercalants within lipid bilayers. To this end, an attempt was made to correlate the (13)C NMR chemical shift of polarizable "reporter" carbons (e.g., carbonyls) of intercalants within DMPC liposomal bilayers - wit...

journal_title：Chemistry and physics of lipids

authors： Afri M,Alexenberg C,Aped P,Bodner E,Cohen S,Ejgenburg M,Eliyahu S,Gilinsky-Sharon P,Harel Y,Naqqash ME,Porat H,Ranz A,Frimer AA

更新日期：2014-12-01 00:00:00

abstract：:Lipoic acid-substituted phospholipids were synthesized from phosphatidyl cholines by exchanging the choline residue with a glycol group using phospholipase D, forming phosphatidylglycols, and coupling of lipoic acid (1,2-dithiolane-3-pentanoic acid) to the residual glycol hydroxyl group by esterification. The thermotr...

journal_title：Chemistry and physics of lipids

authors： Pax H,Blume A

更新日期：1993-11-01 00:00:00

abstract：:We consider the situation of integral membrane proteins in a lipid bilayer matrix where the size of the polar group of the protein is important in determining the lateral packing of the proteins. We represent the cross-section of the protein hydrophobic core as a hexagon moving on a lattice, and represent the projecti...

journal_title：Chemistry and physics of lipids

authors： Pink DA,Chisholm DM,Chapman D

更新日期：1988-04-01 00:00:00

abstract：:[4,4-2H2]-, [5,5-2H2)-, [6-2H]-, [7-2H]-, [8,8-2H2)-, [11,11-2H2]-, [14,14-2H2]- and [18,18,18-2H3]-cis,cis-octadeca-6,9-dienoic (isolinoleic) acid were synthesized by supplementing cultures of the protozoan Tetrahymena with the corresponding deuterated cis-octadeca-9-enoic (oleic) acids. The cultures were harvested, ...

journal_title：Chemistry and physics of lipids

authors： Baenziger JE,Smith IC,Hill RJ

更新日期：1990-04-01 00:00:00

abstract：:Oxidised low density lipoprotein (LDL) was considered to be important in the pathogenesis of atherosclerosis, but the large clinical trials of antioxidants, including the first one using probucol (the PQRST Trial), failed to show benefit and have cast doubt on the importance of oxidised LDL. We have shown previously t...

journal_title：Chemistry and physics of lipids

authors： Ahmad F,Leake DS

更新日期：2018-07-01 00:00:00

abstract：:To investigate the efficacy of reducing plasma lipoprotein(a) (Lp(a)) as well as low density lipoprotein cholesterol (LDL-C) levels on the prevention of restenosis after PTCA, LDL-apheresis was attempted on a total of 54 patients at six institutions. LDL-apheresis using a dextran sulfate cellulose column has been prov...

journal_title：Chemistry and physics of lipids

authors： Yamaguchi H,Lee YJ,Daida H,Yokoi H,Miyano H,Kanoh T,Ishiwata S,Kato K,Nishikawa H,Takatsu F

更新日期：1994-01-01 00:00:00

abstract：:Pulmonary surfactant is a lipid-protein complex, synthesized and secreted by the respiratory epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface tension at the air-liquid interface to minimize the work of breathing. The activity of surfactant at the alveoli involves three main proc...

journal_title：Chemistry and physics of lipids

authors： Serrano AG,Pérez-Gil J

更新日期：2006-06-01 00:00:00

abstract：:Reduction of 3beta-benzoyloxy-14alpha,15alpha-epoxy-5alpha-cholest-7-ene with either lithium triethylboro-hydride or lithium aluminum hydride (4 molar excess) gave 5-alpha-cholest-8(14)-en-3beta,15alpha-diol in high yield. Reduction of the epoxy ester with lithium triethylborodeuteride or lithium aluminum deuteride (4...

journal_title：Chemistry and physics of lipids

authors： Parish EJ,Schroepfer GJ Jr

更新日期：1977-04-01 00:00:00