[Erythrocyte ferritin].

Abstract:

:Red cell ferritin is a residue of erythroblast ferritin. It reflects the balance between the iron supply to the erythroid marrow and the need for haemoglobin synthesis. Erythrocyte ferritin can be measured in haemolysates after discarding plasma and leucocytes by different methods. The decrease in erythrocyte ferritin content indicates manifest iron deficiency anaemia. Ferritin levels do not appear to be influenced by inflammation, infection, tissue necrosis or tumors and may be a reliable indicator of iron status in inflammatory diseases. Erythrocyte ferritin is markedly increased in patients with iron overload allowing early diagnosis of hereditary haemochromatosis and the monitoring of phlebotomy therapy. Finally, in some pathologies erythrocyte assay is a more reliable indicator of the iron status than serum ferritin.

journal_name

Ann Biol Clin (Paris)

authors

Guillemin C,Revenant MC,Vernet M,Dezier JF,Charlier C,Paris M,Pressac M

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

605-9

issue

6

eissn

0003-3898

issn

1950-6112

journal_volume

51

pub_type

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