Abstract:
:Left ventricular topography and diastolic and systolic functions were studied in 41 patients with essential hypertension (group 1) and 33 age-matched normal adults (group 2) by Doppler echocardiography. In group 1 54% had LV concentric hypertrophy, 19% had combined concentric hypertrophy and eccentric remodeling, and 27% had concentric remodeling. LV systolic function was within the normal range. In concentric LV remodeling, the EDV was significantly decreased (compared with group 2) (84 +/- 15 vs 130 +/- 38 ml, p < 0.05), whereas the NPFR was normal (2.89 +/- 0.65 vs 3.22 +/- 0.83 sec-1, p = NS). In concentric hypertrophy, LV end-diastolic and end-systolic volumes were normal, but the NPFR was decreased (2.04 +/- 0.59 sec-1). Patients with concentric hypertrophy and eccentric remodeling had the largest end-diastolic (140 +/- 48 ml) and end-systolic (62 +/- 32 ml) volumes and the lowest NPFR (1.67 +/- 0.69 sec-1). The LVMI inversely correlated with the NPFR (r = -0.89, p < 0.0001). Thus LV concentric hypertrophy with or without concentric or eccentric remodeling is seen in patients with systemic hypertension. A decrease in peak filling occurs early in the evolution of hypertensive heart disease and is observed even when systolic performance is still normal.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Ren JF,Pancholy SB,Iskandrian AS,Lighty GW Jr,Mallavarapu C,Segal BLdoi
10.1016/0002-8703(94)90560-6subject
Has Abstractpub_date
1994-04-01 00:00:00pages
906-13issue
4 Pt 1eissn
0002-8703issn
1097-6744pii
0002-8703(94)90560-6journal_volume
127pub_type
杂志文章abstract:BACKGROUND:Cardiovascular disease is the leading cause of death among blacks and whites in the United States. Despite this, there are insufficient data on the long-term prognosis of black patients with coronary artery disease (CAD) as well as the major clinical related determinants of outcome. METHODS:We studied 22,61...
journal_title:American heart journal
pub_type: 杂志文章
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更新日期:2010-10-01 00:00:00
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更新日期:2005-06-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
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更新日期:1990-12-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,多中心研究
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更新日期:1996-01-01 00:00:00
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journal_title:American heart journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:1996-08-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2006-06-01 00:00:00
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更新日期:1990-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-11-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.12.002
更新日期:2008-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ahj.2005.02.011
更新日期:2006-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2015.12.018
更新日期:2016-04-01 00:00:00
abstract::Estimating left ventricular wall stress has recognized applications, but formulae for global stress cannot be applied to ischemic ventricles. A mathematic method for estimating regional stress in infarcted ventricles has been described. The hypothesis tested was that exercise-induced ischemia increases end-systolic wa...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(96)90305-1
更新日期:1996-10-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2003.11.013
更新日期:2004-05-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1016/j.ahj.2008.05.014
更新日期:2008-09-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90659-w
更新日期:1993-11-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.07.017
更新日期:2005-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0002-8703(88)90061-0
更新日期:1988-05-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:1999-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1067/mhj.2002.123110
更新日期:2002-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.ahj.2004.06.029
更新日期:2005-05-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2004.03.037
更新日期:2004-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(96)90086-1
更新日期:1996-06-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2014.12.022
更新日期:2015-04-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.04.021
更新日期:2016-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(81)80006-3
更新日期:1981-08-01 00:00:00
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journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2010.04.024
更新日期:2010-11-01 00:00:00
abstract::Tolerance to prolonged nitroglycerin (NTG) may be due to drug-induced intravascular expansion. To test the hypothesis that concomitant diuretics may reduce volume expansions and thus prevent NTG tolerance, we studied 23 healthy volunteers randomized to hydrochlorthiazide or placebo before and during 74-hour continuous...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(95)90361-5
更新日期:1995-09-01 00:00:00