Coronary artery size in mitral regurgitation and its regression after mitral valve surgery.

Abstract:

:The relationship between coronary artery size and left ventricular (LV) muscle mass was studied in 10 control subjects and in 10 patients with chronic mitral regurgitation before and 28 +/- 15 months after mitral valve surgery. Left and right coronary artery size was determined by quantitative coronary arteriography. Left coronary artery size was significantly increased before surgery (26 mm2) and decreased after operation (23 mm2), but was still larger than in control subjects (14 mm2). The right coronary artery was also enlarged preoperatively (13 mm2; controls = 9 mm2), but was normalized after surgery (11 mm2). A linear correlation was found between LV muscle mass and left (r = 0.88, p < 0.001) and right coronary artery size (r = 0.84, p < 0.001) as well as between right coronary artery size and mean pulmonary artery pressure (r = 0.56, p < 0.01). Thus in chronic mitral regurgitation the enlargement of the left and right coronary artery is proportional to the degree of LV hypertrophy. The increase in right coronary artery size is probably the result of right ventricular pressure overload. Postoperatively there is only partial regression of left coronary artery size but normalization of right coronary artery size.

journal_name

Am Heart J

journal_title

American heart journal

authors

Vassalli G,Hess OM,Krogmann ON,Villari B,Corin WJ,Turina M,Krayenbuehl HP

doi

10.1016/0002-8703(93)90659-w

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

1091-8

issue

5

eissn

0002-8703

issn

1097-6744

pii

0002-8703(93)90659-W

journal_volume

126

pub_type

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