Rationale and design of a randomized controlled trial of pneumococcal polysaccharide vaccine for prevention of cardiovascular events: The Australian Study for the Prevention through Immunization of Cardiovascular Events (AUSPICE).

abstract：BACKGROUND:The TRANSFER-AMI study demonstrated that early routine percutaneous coronary intervention post-fibrinolysis (pharmacoinvasive strategy) is superior to conservative management for ST-elevation myocardial infarction. However, it is not clear whether treatment efficacy differs between men and women. METHODS:In...

journal_title：American heart journal

authors： Bhan V,Cantor WJ,Yan RT,Mehta SR,Morrison LJ,Heffernan M,Fitchett D,Džavík V,Ducas J,Borgundvaag B,Cohen EA,Goodman SG,Yan AT

更新日期：2012-09-01 00:00:00

abstract：:Despite the well-proven benefits of cardiac rehabilitation and exercise training, no data are available on the benefits of this therapy in patients with preserved baseline exercise capacity. Therefore we assessed data before and after phase II cardiac rehabilitation and exercise programs at two large teaching institut...

journal_title：American heart journal

authors： Lavie CJ,Milani RV

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Nitroglycerin is known to augment vessel wall squeezing at the site with coronary-myocardial bridging (CMB). This study was designed to define the mechanism of nitroglycerin-induced augmentation of CMB in clinical settings. METHODS:We analyzed nitroglycerin reactivity at the site with CMB in 39 patients. Ma...

journal_title：American heart journal

authors： Hongo Y,Tada H,Ito K,Yasumura Y,Miyatake K,Yamagishi M

更新日期：1999-08-01 00:00:00

abstract：:To evaluate whether the identification of the different types of relations between premature ventricular contractions (PVCs) and the preceding sinus cycle length is capable of predicting the effect of beta-blockers on the PVCs themselves, 55 patients (43 men, 12 women, mean age 52.6 +/- 15.6 years) with different card...

journal_title：American heart journal

authors： Pitzalis MV,Mastropasqua F,Massari F,Totaro P,Di Maggio M,Rizzon P

更新日期：1996-03-01 00:00:00

abstract：:Selective inhibition of sinus node function offers the possibility to decrease heart rate and reduce myocardial oxygen consumption in patients with impaired cardiac function, if myocardial contractility is not further attenuated. To study the influence of a specific sinus node inhibitor on myocardial function, alinidi...

journal_title：American heart journal

authors： Koenig W,Stauch M,Sund M,Wanjura D,Henze E

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Pacing leads with a small electrode surface for high-impedance stimulation have been shown to prolong pacemaker longevity, but no sufficient data is available on the safety and feasibility of a defibrillation lead with this novel design. METHODS:We evaluated the clinical performance of a tined, steroid-elut...

journal_title：American heart journal

authors： Vollmann D,Ahern T,Gerritse B,Canby RC,Zenker D,Binner L,Kimber SK,Unterberg C,Worldwide Medtronic Model 6944 Investigators.

更新日期：2003-12-01 00:00:00

abstract：:Intracoronary streptokinase (SK) is being used to treat acute myocardial infarction. Complications including atrioventricular (AV) block and both supraventricular and ventricular arrhythmias have been described. Selective cannulation of the nutrient arteries of the sinus node and AV node in the pentobarbital-anestheti...

journal_title：American heart journal

authors： Epstein AE,Urthaler F,James TN

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:The aim of the study was to describe the incidence and consequences of minor surgery after drug-eluting stent (DES) implantation. METHODS:The Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) Registry prospectively enrolled unselected patients undergoing percutaneous coronary intervention at 47 ...

journal_title：American heart journal

authors： Brilakis ES,Cohen DJ,Kleiman NS,Pencina M,Nassif D,Saucedo J,Piana RN,Banerjee S,Keyes MJ,Yen CH,Berger PB

更新日期：2011-02-01 00:00:00

abstract：AIMS:Cardiac e-consults may be an effective way to deliver value-oriented outpatient cardiology care in an accountable care organization. Initial results of cardiac e-consults have demonstrated high satisfaction among both patients and referring providers, no known adverse events, and low rates of diagnostic testing. N...

journal_title：American heart journal

authors： Wasfy JH,Rao SK,Kalwani N,Chittle MD,Richardson CA,Gallen KM,Isselbacher EM,Kimball AB,Ferris TG

更新日期：2016-03-01 00:00:00

abstract：:Antiarrhythmic therapy for prevention of sustained ventricular tachycardia is commonly guided by programmed electrical stimulation, and the persistent ability to initiate ventricular tachycardia during drug therapy often leads to the use of nonpharmacologic therapies such as surgery. Prior studies suggest that program...

journal_title：American heart journal

authors： Stevenson WG,Weiss J,Oye RK

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Patients undergoing percutaneous coronary intervention (PCI) for unstable coronary syndromes have substantial emotional and spiritual distress that may promote procedural complications. Noetic (nonpharmacologic) therapies may reduce anxiety, pain and distress, enhance the efficacy of pharmacologic agents, or...

journal_title：American heart journal

authors： Krucoff MW,Crater SW,Green CL,Maas AC,Seskevich JE,Lane JD,Loeffler KA,Morris K,Bashore TM,Koenig HG

更新日期：2001-11-01 00:00:00

abstract：:Oxygen free radical scavengers have been found to decrease infarct size in dogs subjected to myocardial ischemia-reperfusion injury. A baboon open-chest model was used to determine if superoxide dismutase (SOD), an oxygen free radical scavenger, together with catalase would be equally effective in subhuman primates (b...

journal_title：American heart journal

authors： Watanabe BI,Premaratne S,Limm W,Mugiishi MM,McNamara JJ

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Achieving a therapeutic international normalized ratio (INR) before hospital discharge is an important inpatient goal for patients undergoing mechanical cardiac valve replacement (MCVR). The use of clinical algorithms has reduced the time to achieve therapeutic INR (TTI) with warfarin therapy. Whether TTI pr...

journal_title：American heart journal

authors： Arendt CJ,Hong JH,Daly RC,Scott C,Mehta RA,Bailey K,Pathak J,Pereira NL

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:A shortcoming of the pediatric electrocardiogram (ECG) appears to be its inability to accurately detect left ventricular hypertrophy (LVH). This study prospectively assesses the usefulness of the pediatric ECG as a screening modality for LVH. METHODS:Concomitant echocardiograms and ECGs from a large cohort ...

journal_title：American heart journal

authors： Rivenes SM,Colan SD,Easley KA,Kaplan S,Jenkins KJ,Khan MN,Lai WW,Lipshultz SE,Moodie DS,Starc TJ,Sopko G,Zhang W,Bricker JT,Pediatric Pulmonary and Cardiovascular Complications of Vertically Transmitted HIV Infection Study Grou

更新日期：2003-04-01 00:00:00

abstract：:In order to correlate the antiarrhythmic and electrophysiological effects of disopyramide phosphate during acute myocardial ischemia, we performed experiments in 17 mongrel dogs. Refractory periods obtained by the extrastimulus method and conduction times recorded from local electrograms were determined in potentially...

journal_title：American heart journal

authors： Levites R,Anderson GJ

更新日期：1979-09-01 00:00:00

abstract：:The role of prostaglandins in mediating the hemodynamic response to nitroglycerin in vivo is controversial. To determine the effect of inhibiting prostaglandin production on the response to nitroglycerin, either placebo or aspirin (650 mg) was administered 1 hour prior to the administration of nitroglycerin (432 micro...

journal_title：American heart journal

authors： Levin RI,Feit F

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:SUPPORT-HF 2 tests the hypothesis that home monitoring with information technology-supported specialist management is more effective in optimizing medical therapy than is home monitoring alone for patients with heart failure. METHODS AND RESULTS:The study was designed as a 2-armed partially blinded parallel...

journal_title：American heart journal

authors： SUPPORT-HF 2 Investigators and Committees. Electronic address: kazem.rahimi@georgeinstitute.ox.ac.uk.

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:This study was designed to investigate the efficacy of alteplase double-bolus dosing compared with the front-loaded 90-minute infusion regimen in patients with acute myocardial infarction. Recent pilot studies have suggested that bolus dosing may provide improved efficacy in establishing early, complete, and...

journal_title：American heart journal

authors： Bleich SD,Adgey AA,McMechan SR,Love TW

更新日期：1998-10-01 00:00:00

abstract：:Previous studies have suggested that the contractility of isolated heart muscle removed from rabbits made hypercholesterolemic is decreased. As part of a study evaluating the effects of high-lipid diets on aortic atherosclerosis, we evaluated the contractility of perfused rabbit hearts. Six rabbits were placed on a hi...

journal_title：American heart journal

authors： Blumlein S,Sievers R,Wikman-Coffelt J,Parmley WW

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Selenium is a central determinant of antioxidative glutathione peroxidase 1 (GPx-1) expression and activity. The relevance of selenium supplementation on GPx-1 in coronary artery disease (CAD) needs to be established. We assessed the effect of selenium supplementation on GPx-1 in cell culture and on endothel...

journal_title：American heart journal

authors： Schnabel R,Lubos E,Messow CM,Sinning CR,Zeller T,Wild PS,Peetz D,Handy DE,Munzel T,Loscalzo J,Lackner KJ,Blankenberg S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Percutaneous coronary intervention (PCI) of saphenous vein graft (SVG) is associated with frequent postprocedural enzyme elevation and late cardiac events. New strategies are proposed to minimize distal embolization and to improve the outcome of patients treated with stenting for SVG lesions. The objectives ...

journal_title：American heart journal

authors： Leborgne L,Cheneau E,Pichard A,Ajani A,Pakala R,Yazdi H,Satler L,Kent K,Suddath WO,Pinnow E,Canos D,Waksman R

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:In patients with acute myocardial infarction (AMI), depressive symptoms increase the risk for cardiac events. Recently, the S allele of the serotonin transporter (5-HTT) gene-linked polymorphic region was shown to reduce transcription of this gene and thus reduce serotonin reuptake, and this allele is linked...

journal_title：American heart journal

authors： Nakatani D,Sato H,Sakata Y,Shiotani I,Kinjo K,Mizuno H,Shimizu M,Ito H,Koretsune Y,Hirayama A,Hori M,Osaka Acute Coronary Insufficiency Study Group.

更新日期：2005-10-01 00:00:00

abstract：:A new mechanically rotated 20 MHz intravascular ultrasound guide wire (0.032 inch) with a transducer core was placed through the central lumen of a peripheral arterial balloon-expandable stent. Using an anesthetized canine model, 11 stents were then deployed into the iliac or femoral arteries. Eight stents were succes...

journal_title：American heart journal

authors： Tenaglia AN,Kisslo K,Kelly S,Hamm MA,Crowley R,Davidson CJ

更新日期：1993-05-01 00:00:00

abstract：:A new shape-memory coil for transcatheter closure of the PDA was developed and evaluated in a dog PDA model. The coil is sensitive to temperature (composed of thermal shape-memory nickel-titanium). The coil was delivered to and implanted in the PDA model with a 5F catheter through the femoral artery. The PDA model was...

journal_title：American heart journal

authors： Liu C,Shiraishi H,Kikuchi Y,Yanagisawa M

更新日期：1996-05-01 00:00:00

abstract：:Left ventricular (LV) thrombi are responsible for significant morbidity and mortality in our society. Twenty-five percent of cardiogenic emboli are associated with acute and chronic myocardial infarction. With the development of noninvasive imaging techniques LV thrombi have been increasingly recognized as an importan...

journal_title：American heart journal

authors： Cregler LL

更新日期：1992-04-01 00:00:00

abstract：:Pulsed Doppler echocardiographic studies of both right and left ventricular diastolic inflow patterns were performed in 10 full-term newborn infants and serially during the first month of life in 21 premature (28 to 35 weeks' gestation) infants with no clinical cardiorespiratory disease. Results of studies performed d...

journal_title：American heart journal

authors： Johnson GL,Moffett CB,Noonan JA

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that the adenosine monophosphate deaminase 1 (AMPD1) C34T polymorphism may be associated with survival in cardiac populations with a protective effect of the T allele. However, these studies included limited number of patients with few cardiovascular events. METHODS:We pro...

journal_title：American heart journal

authors： de Groote P,Lamblin N,Helbecque N,Mouquet F,Hermant X,Amouyel P,Dallongeville J,Bauters C

更新日期：2006-10-01 00:00:00

abstract：:Hypertensive cardiovascular risk may be related primarily to vascular overload, the sum of three vascular abnormalities: increased arteriolar resistance, increased large-artery stiffness, and the effect of increased early pulse-wave reflection. A method for quantifying vascular overload as an index can be derived from...

journal_title：American heart journal

authors： Franklin SS,Weber MA

更新日期：1994-10-01 00:00:00

abstract：:The actions of the beta-adrenergic receptor antagonist, d,l-nadolol, were examined in anesthetized dogs subjected to circumflex coronary artery ligation in the presence of previous anterior myocardial infarction. With circumflex ligation, control dogs (N = 18) developed premature ventricular beats and ventricular tach...

journal_title：American heart journal

authors： Patterson E,Lucchesi BR

更新日期：1988-11-01 00:00:00

abstract：:Ventricular tachyarrhythmias are the cause of sudden cardiac death in ischemic heart disease. Reliable animal models are necessary to study techniques for identifying individuals at risk and to develop effective modes of therapy. The purpose of the present study was to evaluate the inducibility of ventricular tachyarr...

journal_title：American heart journal

authors： Wetstein L,Mark R,Kelliher GJ,Friehling T,O'Connor KM,Kowey PR

更新日期：1985-11-01 00:00:00