Mortality benefits and the implantable cardioverter-defibrillator.

abstract：BACKGROUND:In various heart disease paradigms, atria show stronger fibrotic responses than ventricles. The possibility that atrial and ventricular fibroblasts respond differentially to pathological stimuli has not been examined. METHODS AND RESULTS:We compared various morphological, secretory, and proliferative respon...

journal_title：Circulation

authors： Burstein B,Libby E,Calderone A,Nattel S

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:This article presents an update of the results achieved by modern surgery in congenital heart defects (CHDs) over the past 40 years regarding survival and the need for reoperations, especially focusing on the results from the past 2 decades. METHODS AND RESULTS:From 1971 to 2011, all 7038 patients <16 years...

journal_title：Circulation

authors： Erikssen G,Liestøl K,Seem E,Birkeland S,Saatvedt KJ,Hoel TN,Døhlen G,Skulstad H,Svennevig JL,Thaulow E,Lindberg HL

更新日期：2015-01-27 00:00:00

abstract：BACKGROUND:Angiotensin (Ang) II type 1 receptor (AT1-R) induces cardiomyocyte hypertrophy and fibroblast proliferation, whereas the physiological role of AT2-R in cardiac remodeling remains poorly defined. METHODS AND RESULTS:Using Bio14.6 cardiomyopathic (CM) hamsters, we found that AT2-R sites were increased by 153%...

journal_title：Circulation

authors： Ohkubo N,Matsubara H,Nozawa Y,Mori Y,Murasawa S,Kijima K,Maruyama K,Masaki H,Tsutumi Y,Shibazaki Y,Iwasaka T,Inada M

更新日期：1997-12-02 00:00:00

abstract：BACKGROUND:Hypertension and other vascular diseases are more prevalent in diabetic patients than in the general population. In humans and in several animal models of diabetes, a disturbance of endothelium-dependent responses has been shown. Oxyhemoglobin is one of the most known modulators of these endothelium-dependen...

journal_title：Circulation

authors： Rodríguez-Mañas L,Arribas S,Girón C,Villamor J,Sánchez-Ferrer CF,Marín J

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Catheter ablation of the posteroseptal right atrium has been proposed for control of ventricular rate in patients with tachycardic atrial fibrillation (AF). However, the exact mechanism of rate control is unclear. Because the ablation site corresponds to the location of the slow pathway in patients with AV n...

journal_title：Circulation

authors： Kreiner G,Heinz G,Siostrzonek P,Gössinger HD

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the leading cause of death for both men and women in the United States and the world. A profound pattern exists in the time of day at which the death occurs; it is in the morning, when the endothelium is most vulnerable and blood pressure surges, that stroke and heart attack most fr...

journal_title：Circulation

authors： Anea CB,Zhang M,Stepp DW,Simkins GB,Reed G,Fulton DJ,Rudic RD

更新日期：2009-03-24 00:00:00

abstract：BACKGROUND:Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipose-specific plasma protein, accumulated to the injured artery and attenuated vascular inflammatory response. Clinically, high plasma adiponect...

journal_title：Circulation

authors： Kumada M,Kihara S,Ouchi N,Kobayashi H,Okamoto Y,Ohashi K,Maeda K,Nagaretani H,Kishida K,Maeda N,Nagasawa A,Funahashi T,Matsuzawa Y

更新日期：2004-05-04 00:00:00

abstract：:The patterns of aortic and tricuspid valve motion in 50 patients with mitral valve prolapse were analyzed by wide-angle, phased-array, two-dimensional echocardiography. Twelve patients (24%) had redundant aortic leaflets bulging into the left ventricular outflow tract during diastole. Eight of 12 patients had aortic r...

journal_title：Circulation

authors： Ogawa S,Hayashi J,Sasaki H,Tani M,Akaishi M,Mitamura H,Sano M,Hoshino T,Handa S,Nakamura Y

更新日期：1982-01-01 00:00:00

abstract：:We examined the cardiopulmonary effects of maximum bicycle ergometer exercise in seven patients with implanted Intermedics Nova MR pacemakers for three types of pacing in a randomized sequence: VVI or AAI at 70 beats/min (SSI 70), rate-adaptive temperature-controlled pacing with the implanted Nova MR, and rate-adaptiv...

journal_title：Circulation

authors： Alt E,Völker R,Högl B,MacCarter D

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells (MSCs) are bone marrow stromal cells that are in phase 1 clinical studies of cellular cardiomyoplasty. However, the electrophysiological effects of MSC transplantation have not been studied. Although improvement of ventricular function would represent a positive outcome of MSC transpla...

journal_title：Circulation

authors： Chang MG,Tung L,Sekar RB,Chang CY,Cysyk J,Dong P,Marbán E,Abraham MR

更新日期：2006-04-18 00:00:00

abstract：BACKGROUND:Despite the fact that nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated among patients with established cardiovascular disease, many receive NSAID treatment for a short period of time. However, little is known about the association between NSAID treatment duration and risk of cardiovascular d...

journal_title：Circulation

authors： Schjerning Olsen AM,Fosbøl EL,Lindhardsen J,Folke F,Charlot M,Selmer C,Lamberts M,Bjerring Olesen J,Køber L,Hansen PR,Torp-Pedersen C,Gislason GH

更新日期：2011-05-24 00:00:00

abstract：BACKGROUND:Angiotensin II (Ang II) plays a critical role in the development of vascular lesions in hypertension, atherosclerosis, and several renal diseases. Because Ang II may contribute to the leukocyte recruitment associated with these pathological states, the aim of the present study was to assess the role of Ang I...

journal_title：Circulation

authors： Piqueras L,Kubes P,Alvarez A,O'Connor E,Issekutz AC,Esplugues JV,Sanz MJ

更新日期：2000-10-24 00:00:00

abstract：BACKGROUND:Specific thrombin inhibitors are considered to be more potent antithrombotics than heparin. However, the relation between the systemic anticoagulation generated by thrombin inhibitors and their antithrombotic effect is not well defined. In a guinea pig carotid thrombosis model, the activated clotting time (A...

journal_title：Circulation

authors： Carteaux JP,Gast A,Tschopp TB,Roux S

更新日期：1995-03-01 00:00:00

abstract：BACKGROUND:The Ross operation is an alternative to mechanical aortic valve replacement in the young. Early dilatation of the pulmonary autograft root exposed to the systemic circulation has been reported. To define the prevalence of, risk factors for, and consequences of late autograft dilatation, outcome in all consec...

journal_title：Circulation

authors： Luciani GB,Casali G,Favaro A,Prioli MA,Barozzi L,Santini F,Mazzucco A

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:There has been increasing interest in the development of agents that utilize endogenous adenosine to exert their actions. We tested the hypothesis that substances that either potentiate the activity (allosteric enhancers) or increase the interstitial concentration (inhibitors of metabolism) of endogenous ade...

journal_title：Circulation

authors： Dennis DM,Raatikainen MJ,Martens JR,Belardinelli L

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:The study was designed to verify the concept of plaques "at risk" and whether inflammation could play a role in plaque rupture and thrombosis. METHODS AND RESULTS:In 20 patients who had died of acute myocardial infarction, the thrombosed coronary artery was identified and the site of plaque rupture was trac...

journal_title：Circulation

authors： van der Wal AC,Becker AE,van der Loos CM,Das PK

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We measured the content and activities of components of the beta-adrenergic receptor-G protein-adenylate cyclase complex and adrenergic neurotransmitter levels in left and right ventricular myocardial preparations derived from 77 end-stage failing human hearts from patients with idiopathic dilated cardiomyop...

journal_title：Circulation

authors： Bristow MR,Anderson FL,Port JD,Skerl L,Hershberger RE,Larrabee P,O'Connell JB,Renlund DG,Volkman K,Murray J

更新日期：1991-09-01 00:00:00

abstract：:A new technology, leadless pacemaker therapy, was recently introduced clinically to address lead- and pocket-related complications in conventional transvenous pacemaker therapy. These leadless devices are self-contained right ventricular single-chamber pacemakers implanted by using a femoral percutaneous approach. In ...

journal_title：Circulation

authors： Tjong FV,Reddy VY

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:The biological response to antiplatelet drugs has repeatedly been shown to predict the recurrence of major adverse cardiovascular events (MACEs). However, most studies involved coronary artery disease patients with recent vessel injury shortly after the initiation of antiplatelet therapy. Data on stable card...

journal_title：Circulation

authors： Reny JL,Berdagué P,Poncet A,Barazer I,Nolli S,Fabbro-Peray P,Schved JF,Bounameaux H,Mach F,de Moerloose P,Fontana P,Antiplatelet Drug Resistances and Ischemic Events (ADRIE) Study Group.

更新日期：2012-06-26 00:00:00

abstract：BACKGROUND:Plasma C-reactive protein (CRP) concentrations are increased in obese and/or hyperinsulinemic individuals. The goal of this study was to determine if the relation between insulin resistance and CRP was independent of obesity. METHODS AND RESULTS:Plasma CRP concentrations were measured before and after 3 mon...

journal_title：Circulation

authors： McLaughlin T,Abbasi F,Lamendola C,Liang L,Reaven G,Schaaf P,Reaven P

更新日期：2002-12-03 00:00:00

abstract：:Thirteen male patients with NYHA class IV congestive heart failure refractory to conventional therapy were treated with oral fenoximone, a new imidazole compound with inotropic and vasodilator effects, for a mean duration of 11 weeks (range 2 to 34). On initial hemodynamic evaluation, the effects of oral fenoximone we...

journal_title：Circulation

authors： Shah PK,Amin DK,Hulse S,Shellock F,Swan HJ

更新日期：1985-02-01 00:00:00

abstract：:Between 1972 and 1984, 100 consecutive neonates (less than or equal to 30 days old) underwent repair of coarctation of the aorta. Mean (+/- SD) age at operation was 12.0 +/- 8.0 days; mean weight was 3.1 +/- 0.5 kg. Simple coarctation was present in 29 patients (group I), 32 patients had additional ventricular septal ...

journal_title：Circulation

authors： Ziemer G,Jonas RA,Perry SB,Freed MD,Castaneda AR

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Progression of heart failure after initial myocardial injury is mediated in part by various redundant inflammatory mediators, including the widely expressed cyclooxygenase-2 (COX-2). Because COX-2 inhibitors are useful in treating many inflammation-mediated diseases, we asked whether COX-2 inhibition can att...

journal_title：Circulation

authors： Delgado RM 3rd,Nawar MA,Zewail AM,Kar B,Vaughn WK,Wu KK,Aleksic N,Sivasubramanian N,McKay K,Mann DL,Willerson JT

更新日期：2004-03-23 00:00:00

abstract：BACKGROUND:The combination of a single-bolus fibrinolytic and a low-molecular-weight heparin may facilitate prehospital reperfusion and further improve clinical outcome in patients with ST-elevation myocardial infarction. METHODS AND RESULTS:In the prehospital setting, 1639 patients with ST-elevation myocardial infarc...

journal_title：Circulation

authors： Wallentin L,Goldstein P,Armstrong PW,Granger CB,Adgey AA,Arntz HR,Bogaerts K,Danays T,Lindahl B,Mäkijärvi M,Verheugt F,Van de Werf F

更新日期：2003-07-15 00:00:00

abstract：BACKGROUND:Low-density lipoprotein (LDL) impairs endothelial cell function by uncoupling endothelial nitric oxide synthase (eNOS) activity, which allows superoxide anion (O2*-)) to be generated rather than nitric oxide (*NO). Recent reports indicate that apolipoprotein (apo) A-1 mimetics inhibit the development of athe...

journal_title：Circulation

authors： Ou Z,Ou J,Ackerman AW,Oldham KT,Pritchard KA Jr

更新日期：2003-03-25 00:00:00

abstract：BACKGROUND:Worldwide, diabetes mellitus and heart failure represent frequent comorbidities with high socioeconomic impact and steadily growing incidence, calling for a better understanding of how diabetic metabolism promotes cardiac dysfunction. Paradoxically, some glucose-lowering drugs have been shown to worsen heart...

journal_title：Circulation

authors： Kronlage M,Dewenter M,Grosso J,Fleming T,Oehl U,Lehmann LH,Falcão-Pires I,Leite-Moreira AF,Volk N,Gröne HJ,Müller OJ,Sickmann A,Katus HA,Backs J

更新日期：2019-08-13 00:00:00

abstract：BACKGROUND:The effects of ultrasound-guided high-pressure stenting on late stent and reference segment dimensions are unknown. In this study, we report about angiographic and ultrasound measurements to assess the amount and distribution of neointimal ingrowth within the stent and the changes of plaque burden and dimens...

journal_title：Circulation

authors： Mudra H,Regar E,Klauss V,Werner F,Henneke KH,Sbarouni E,Theisen K

更新日期：1997-01-21 00:00:00

abstract：:The relation between left atrial size and atrial fibrillation was examined in 37 patients who had left ventriculomyotomy and myectomy at the National Heart and Lung Institute. Atrial fibrillation was present in 11 of 27 (41%) patients with an echocardiographically measured left atrial dimension greater than 45 mm. No ...

journal_title：Circulation

authors： Watson DC,Henry WL,Epstein SE,Morrow AG

更新日期：1977-01-01 00:00:00

abstract：:Between 1970 and 1987, 112 patients were diagnosed as having thromboangiitis obliterans (TAO). The age was 42 +/- 11 years (mean +/- SD; range, 20-75 years); 23% were women, and 7% were more than 60 years old when they were first diagnosed. Ischemic ulcerations were present in 85 (76%) patients: 24 (28%) patients with...

journal_title：Circulation

authors： Olin JW,Young JR,Graor RA,Ruschhaupt WF,Bartholomew JR

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Radiofrequency ablation of type 1 atrial flutter (AF1) has recently evolved toward an anatomically guided procedure directed to isthmuses at the lower part of the right atrium (RA). However, different types of block at these isthmuses may be observed and potentially correlated with different late outcomes. I...

journal_title：Circulation

authors： Poty H,Saoudi N,Nair M,Anselme F,Letac B

更新日期：1996-12-15 00:00:00