Abstract:
:We report three cases of Hodgkin's disease with coexistent histologic features reminiscent of Castleman's disease. In each case, reactive follicular hyperplasia was prominent and lymphoid follicles contained normal- or small-sized germinal centers. In two lesions, sheets of mature plasma cells and vascular proliferation were present in the interfollicular region, and some of the follicle centers were small, relatively depleted of lymphoid cells, and surrounded by concentric layers of small lymphocytes (so-called onionskin layers). However, unequivocal hyaline-vascular lesions were absent. Both cases were referred with the diagnosis of Castleman's disease, most consistent with the plasma cell variant. Subsequent review demonstrated scattered Reed-Sternberg and Hodgkin cells in the interfollicular region, highlighted by immunohistochemical studies, and the diagnosis of interfollicular Hodgkin's disease was made. In the third lesion, the majority of the lymph node was replaced by Hodgkin's disease, nodular lymphocyte predominance subtype. In the regions not involved by tumor, reactive lymphoid follicles with hyaline-vascular lesions were numerous. This case was also referred with the diagnosis of Castleman's disease, of the hyaline-vascular type. We report these lesions to emphasize that histologic features reminiscent of Castleman's disease may occur in lymph nodes involved by Hodgkin's disease, resulting in diagnostic confusion. Castleman-like histologic features may represent a nonspecific immune response to a variety of immunologic stimuli including, as in these cases, the presence of Hodgkin's disease. The possibility of Hodgkin's disease needs to be considered and excluded before the diagnosis of Castleman's disease is made.
journal_name
Arch Pathol Lab Medjournal_title
Archives of pathology & laboratory medicineauthors
Zarate-Osorno A,Medeiros LJ,Danon AD,Neiman RSsubject
Has Abstractpub_date
1994-03-01 00:00:00pages
270-4issue
3eissn
0003-9985issn
1543-2165journal_volume
118pub_type
杂志文章abstract:OBJECTIVE:To determine the diagnostic accuracy of an investigational test for human immunodeficiency virus (HIV) envelope antibodies in urine. DESIGN:Matched blood and urine specimens were tested for HIV by two independent laboratories, both of which were blinded to all results at the other site. Duplicate positive en...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00
abstract:CONTEXT:The skeletal system may be affected by a variety of nonneoplastic lesions, which may potentially be confused with primary bone tumors on clinical, radiologic, and pathologic grounds. These conditions include fractures, infections, and reactive and degenerative processes, as well as an array of quasineoplastic e...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.5858/arpa.2011-0557-RA
更新日期:2012-07-01 00:00:00
abstract:CONTEXT:Signet-ring cell carcinoma (SRCC) is a poorly differentiated mucin-producing adenocarcinoma that may arise from many different organs, but all SRCCs share identical morphology. It is not possible to differentiate sites of origin for metastatic SRCC based on morphology alone. Mucins are high-molecular-weight gly...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165(2006)130[799:MPISCC]2.0.CO;2
更新日期:2006-06-01 00:00:00
abstract:CONTEXT:Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys. OBJECTIVE:To determine whether successful completion of the College of American Pathologists LN surveys provides a benefit in term...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165(2004)128<544:CVPRTP>2.0.CO;2
更新日期:2004-05-01 00:00:00
abstract::Over a 3-month period, 61,496 errors were detected in clinical laboratory reports by 631 participants in the College of American Pathologists' 1990 Q-Probes program. Each error detected was defined as an opportunity for improvement. Almost 4% of the detected errors were attributed to nonlaboratory personnel and approx...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::Toxoplasmosis is a common opportunistic pathogen in patients with acquired immunodeficiency syndrome (AIDS). It usually presents with ocular, central nervous system, or pulmonary disease. Gastric toxoplasmosis is uncommon in AIDS patients, especially in the absence of central nervous system manifestations. In the few ...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.1043/1543-2165(2003)127<732:GTIAPW>2.0.CO;2
更新日期:2003-06-01 00:00:00
abstract::The association of cancer and death in laypeoples' thinking has resulted in discussions of cancer diagnoses often being held sub rosa. Open acceptance of a diagnosis of cancer cannot only help to dispel associated fears but also can serve to educate other persons to recognize that cancers can be cured. Open discussion...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for mu...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.1043/0003-9985(2001)125<0152:PLOTP>2.0.CO;2
更新日期:2001-01-01 00:00:00
abstract::Silicone breast prostheses are medical devices, implanted subcutaneously or subpectorally, that are designed to replace or augment the volume occupied by breast glandular tissue. They are generally effective in creating tissue mounds, and their apparent medical benefit is primarily psychological. Recent data on immuno...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract::We investigated how route of infection with Treponema pallidum affects cellular responses of various lymphoid tissues. Lymphoid cells from spleens and lymph nodes of rabbits infected intradermally with T pallidum showed enhanced in vitro responses to treponemal antigens when cultured in autologous rabbit serum. Intrav...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1982-09-01 00:00:00
abstract::The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::A review was made of the clinical histories, treatment, and renal histologic features of 12 patients with anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM disease). Two patients had milder histopathologic changes in their kidney biopsy specimens and achieved clinical remission. The other...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1984-09-01 00:00:00
abstract:CONTEXT:- Fine-needle aspiration of thyroid nodules is a reliable diagnostic method to determine the nature of thyroid nodules. Nonetheless, indeterminate cytology diagnoses remain a diagnostic challenge. The development of multiplex molecular techniques and the identification of genetic alterations associated with dif...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.5858/arpa.2016-0100-RA
更新日期:2016-12-01 00:00:00
abstract::To examine the role of sputum examination in the diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS), we conducted a prospective study of 30 patients with AIDS or suspected AIDS. Sputum was obtained just prior to bronchoscopy by spontaneous cough (20 patients) or ...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::Congenital syphilis remains a public health concern in the United States. Infants whose mothers are treated in the third trimester without adequate prenatal care have an increased risk of morbidity and mortality in the immediate perinatal period. The identification of Treponema pallidum in tissue is definitive confirm...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/0003-9985(2002)126<0484:PAICS>2.0.CO;2
更新日期:2002-04-01 00:00:00
abstract::The pathologic aspects of an uncommon complication of diabetes mellitus, destructive arthropathy (Charcot's joint), were studied. The peripheral nerve demyelination resulting in clinically demonstrable deficits in perception of pain and vibration and in reflexes in the lower extremities reinforces the neurogenic role ...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1982-07-01 00:00:00
abstract:OBJECTIVE:To develop a multi-institutional reference database of extraneous tissue (contaminants) in surgical pathology. DESIGN:In 1994, participants in the College of American Pathologists Q-Probes quality improvement program performed prospective and retrospective evaluations of extraneous tissue found in surgical p...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1996-11-01 00:00:00
abstract::The increasing interest in geriatric medicine demands an understanding of aging in human tissues. The changes in the human heart are an important aspect of this understanding because cardiovascular diseases are a leading medical problem in the elderly. The published data about age-related changes in the human myocardi...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1990-09-01 00:00:00
abstract::The pathologic correlate of the clinical terms subendocardial and transmural applied to myocardial infarcts is uncertain. To examine this question, we reviewed the morphology of 204 hearts with single myocardial infarcts studied at autopsy after coronary arteriography and fixation in distention. The thickness of survi...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1986-05-01 00:00:00
abstract:CONTEXT:Most posttransplantation lymphoproliferative disorders (PTLDs) are associated with Epstein-Barr virus (EBV) infection. The EBV latent membrane protein 1 (LMP-1) is important in the transformation of B lymphocytes through its interaction with intracellular tumor necrosis factor receptor-associated factors (TRAFs...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165(2003)127<1335:LMPTNF>2.0.CO;2
更新日期:2003-10-01 00:00:00
abstract::Ciliated hepatic foregut cysts are rare congenital lesions derived from the embryologic foregut. They are considered benign, and a review of 64 published cases revealed no instances of malignant transformation. We report a case of squamous cell carcinoma arising in a ciliated hepatic foregut cyst in a 51-year-old man....
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/0003-9985(1999)123<1115:SCCAIA>2.0.CO;2
更新日期:1999-11-01 00:00:00
abstract::Periosteal osteoblastoma is an extremely rare bone-forming neoplasm located on the surface of cortical bone. Of the fewer than 30 cases of periosteal osteoblastomas found in the literature, 2 have been reported to be located in cranial bone, and these have not been documented in detail with clinical history, radiograp...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165(2005)129[787:ARCOPO]2.0.CO;2
更新日期:2005-06-01 00:00:00
abstract::The postmortem tissue distribution of cholesterol precursors, squalene, and methyl sterols was quantitated in ten human subjects by the use of gas-liquid chromatography. Five methyl sterol subfractions were found, with each organ having a pattern of its own. The mean esterification percentage of the methyl sterol mixt...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::Intraosseous benign notochordal cell tumor is a presumably benign, intravertebral lesion of notochord origin, which can be found incidentally on removal of the vertebra for unrelated lesions or during an autopsy. The notion of a larger benign notochordal cell tumor that is macroscopic, occasionally symptomatic, and se...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.1043/1543-2165-134.2.283
更新日期:2010-02-01 00:00:00
abstract:CONTEXT:Solitary fibrous tumors (SFTs) of the central nervous system are rare neoplasms that usually present as dura-based masses and clinically resemble meningiomas. Histologically, they can be similar to fibrous meningioma or hemangiopericytoma (HPC). In particular, densely cellular regions seen in some SFTs can be i...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,多中心研究,评审
doi:10.1043/0003-9985(2003)127<0432:SFTITC>2.0.CO;2
更新日期:2003-04-01 00:00:00
abstract::Fibrolamellar carcinoma is a rare primary hepatocellular malignancy arising in noncirrhotic livers of young individuals. Patients commonly present with a large solitary liver mass and nonspecific symptoms. Characteristic histologic features include large polygonal cells with oncocytic cytoplasm and prominent nucleoli ...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.5858/arpa.2017-0083-RS
更新日期:2018-09-01 00:00:00
abstract::A case of epithelioid sarcoma was studied light microscopically, ultrastructurally, and immunohistologically. The tumor was a deep antebrachial mass in a 57-year-old man, and led to antebrachial amputation. Light microscopically, the tumor consisted of nodules that often had central necrosis. The cells were uniform, w...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1982-11-01 00:00:00
abstract::A case of endomyocardial fibrosis with intramyocardial calcification was characterized by symptoms of restrictive cardiomyopathy resembling constrictive pericarditis. Pathological findings were typical of those found in classical Davies' disease, originally encountered and described in Uganda. ...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1978-08-01 00:00:00
abstract:CONTEXT:Correction factors have been proposed for estimating true potassium concentrations in blood samples with evidence of in vitro hemolysis. OBJECTIVE:We used 2 different models of true (ie, nonsimulated) in vitro hemolysis to evaluate the clinical utility of correction factors for estimating potassium concentrati...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165-133.6.960
更新日期:2009-06-01 00:00:00
abstract::Invasive lobular carcinoma of the breast is a relatively common diagnosis. However, other carcinomatous as well as noncarcinomatous neoplasms, either primary or metastatic to the breast, may mimic invasive lobular carcinoma. As treatment may differ, establishing the correct diagnosis is paramount to providing the appr...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.5858/arpa.2015-0190-RA
更新日期:2015-10-01 00:00:00