Abstract:
:Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for muscle-specific actin, alpha-smooth muscle actin, and basement membrane components, along with negative staining for epithelial and neural markers, were consistent with a smooth muscle sarcoma. The patient died of disease 1 year after complete surgical excision. This report highlights the need to use a complete antibody panel in order to accurately immunophenotype pleomorphic malignant tumors of the pancreas. A review of the cases compiled in the literature indicates that pancreatic leiomyosarcoma, like its counterpart arising in deep soft tissues, is an aggressive neoplasm characterized by short survival and a high rate of metastases.
journal_name
Arch Pathol Lab Medjournal_title
Archives of pathology & laboratory medicineauthors
Nesi G,Pantalone D,Ragionieri I,Amorosi Adoi
10.1043/0003-9985(2001)125<0152:PLOTP>2.0.CO;2subject
Has Abstractpub_date
2001-01-01 00:00:00pages
152-5issue
1eissn
0003-9985issn
1543-2165journal_volume
125pub_type
杂志文章,评审abstract::We encountered a rare case of pulmonary phaeohyphomycosis due to Xylohypha bantiana documented by culture. This dematiaceous (darkly pigmented) fungus is primarily neurotropic. It usually produces phaeohyphomycosis of the central nervous system but may also involve the skin and subcutaneous tissues. The patient, a 49-...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::Fifty-three skin biopsy specimens obtained from the cutaneous rashes of patients who had dengue hemorrhagic fever (DHF) were studied by immunofluorescence technique. Six specimens showed deposits of IgM, beta 1 C-globulin, dengue antigen, and fibrinogen during the first week of fever. Some but not all of these compone...
journal_title:Archives of pathology & laboratory medicine
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abstract::We report a case of sialadenoma papilliferum arising in the adenoids in a 2-year-old child. The tumor demonstrated papillary and adenomatous proliferations, suggestive of minor salivary gland origin. A review of the literature indicated no reported cases of this neoplasm arising in individuals this young. The location...
journal_title:Archives of pathology & laboratory medicine
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abstract::Fusarium species are saprophytic fungi that may colonize human skin and nails and may rarely cause invasive infections in traumatized tissue and in debilitated and immunocompromised patients. We report herein a case of invasive intranasal Fusarium oxysporum infection in a diabetic patient. This unusual presentation po...
journal_title:Archives of pathology & laboratory medicine
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更新日期:1986-08-01 00:00:00
abstract:CONTEXT:Radiologic studies are obtained for diagnostic and treatment planning purposes in the evaluation of patients with intracranial neoplasms. These studies are discussed at radiology/pathology working conferences and are often beneficial in the analysis of pathologic specimens for tissue diagnosis. Therefore, clini...
journal_title:Archives of pathology & laboratory medicine
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abstract::The evolution of proteinuria in rabbits with experimentally induced chronic serum sickness was followed up longitudinally by analytical and quantitative assays. The results suggest that sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) is a more sensitive index of kidney malfunction than are total-p...
journal_title:Archives of pathology & laboratory medicine
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abstract:CONTEXT:No study has evaluated radiology/pathology correlation of percentage viable tumor (PVT) estimates in ablated hepatocellular carcinoma (HCC) to examine the reliability of radiologic estimates. OBJECTIVE:To determine how well interdisciplinary PVT estimates correlate and identify pathologic factors that influenc...
journal_title:Archives of pathology & laboratory medicine
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journal_title:Archives of pathology & laboratory medicine
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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journal_title:Archives of pathology & laboratory medicine
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更新日期:2003-09-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1986-11-01 00:00:00
abstract::A certain proportion of soft-tissue sarcomas are difficult to classify accurately. In this case report, initial light microscope observations of a soft-tissue tumor suggested a diagnosis of a monophasic synovial sarcoma. However, critical evaluation of the histologic features, results of studies with special stains, a...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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更新日期:1981-04-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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更新日期:2001-04-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:
更新日期:1992-12-01 00:00:00
abstract:CONTEXT:- Fine-needle aspiration of thyroid nodules is a reliable diagnostic method to determine the nature of thyroid nodules. Nonetheless, indeterminate cytology diagnoses remain a diagnostic challenge. The development of multiplex molecular techniques and the identification of genetic alterations associated with dif...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
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更新日期:2016-12-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
doi:10.5858/arpa.2014-0061-RA
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abstract::We report a case of fatal fibrosing peritonitis in a 28-year-old drug abuser. The extensive fibrosis, which was limited to the abdominal cavity, contained birefringent material. Silica was identified by spectrophotometric analysis. Silica is a component of talc (magnesium silicate) used as a drug filler. Relatively sm...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
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更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To better understand immunologic and pathophysiologic changes in the spleen in chronic immune thrombocytopenic purpura. DESIGN:We performed immunohistochemical studies on 12 spleens of patients with immune thrombocytopenic purpura. RESULTS:Four spleens had prominent hyperplastic secondary follicles in the w...
journal_title:Archives of pathology & laboratory medicine
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更新日期:1995-06-01 00:00:00
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journal_title:Archives of pathology & laboratory medicine
pub_type: 传,历史文章,杂志文章
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abstract::Secretory breast carcinoma is a rare breast cancer. It occurs in all age groups, with the majority of patients being adults. It is a rare occurrence in elderly (>50 years) patients; only 5 cases have been reported in this patient group in the English literature. It is even rarer in males, with only 15 cases reported i...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:10.1043/1543-2165(2006)130[1073:PBLIAE]2.0.CO;2
更新日期:2006-07-01 00:00:00
abstract::Leydig cell tumor (LCT) is a rare tumor of the male testicular interstitium. This article provides an overview of the major pathologic manifestations of LCT of the testis; patient characteristics; clinical, radiologic, and laboratory features; prognosis; and management. LCTs of the testis are frequently hormonally act...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章,评审
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更新日期:2007-02-01 00:00:00
abstract::The objective of this study was to evaluate conjunctival nevi for p53 gene mutations. We studied 11 conjunctival nevi by immunohistochemistry with the DO7 monoclonal p53 antibody as well as the cell proliferation marker, MIB1. Of the 11 cases, 2 were negative, 2 had less than 1%, and 7 had more than 2% p53 immunoposit...
journal_title:Archives of pathology & laboratory medicine
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更新日期:1996-04-01 00:00:00
abstract:CONTEXT:- The Ki-67 index is strongly prognostic and is used as a surrogate marker to distinguish luminal A from luminal B breast cancer types. OBJECTIVE:- To investigate differences in Ki-67 index between core needle biopsy samples and matched surgical samples in breast cancer. DESIGN:- We included patients with inv...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
abstract::The usual gross appearance of a renal oncocytoma is that of a well-circumscribed homogeneous tan-brown tumor with no evidence of necrosis or hemorrhage, but with a central fibrous scar. We describe a case of renal oncocytoma with the unusual gross appearance of a cystic tumor. While cystic change has occasionally been...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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更新日期:1987-05-01 00:00:00
abstract::A case of pronounced cystic dilatation of the intrahepatic bile ducts with biliary atresia is presented. Intrahepatic biliary cysts have been described in biliary atresia, although, as far as we are aware, none as extensive as in this case. The cysts represent end-stage obstruction with irreversible liver injury; thus...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVE:To delineate changes that occur in various parameters of automated complete blood cell count (CBC) and differential leukocyte count (differential) on prolonged storage of blood at room temperature. DESIGN:A CBC and an automated differential were performed on the Coulter Gen.S on 40 K(3) (tripotassium ethylen...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
abstract::Forty-six carcinoid tumors of the appendix, diagnosed in surgically resected specimens during an 11-year period (1965 to 1975) were reviewed to determine the features of metastasizing tumors. Of the carcinoid tumors of the appendix, 8.8% were found to metastasize to regional lymph nodes. The most reliable criterion of...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract::The Mayo Clinic (Rochester, Minn) Division of Transfusion Medicine evaluated the effect of methods of error detection, analysis, and prevention on the rate of errors occurring from 1982 through 1992. We defined an error as any deviation from the standard operating procedure. Twenty-four standard operating procedures w...
journal_title:Archives of pathology & laboratory medicine
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00