Cytokeratin-positive, CD45-negative primary centroblastic lymphoma of the adrenal gland: a potential for a diagnostic pitfall.

abstract：CONTEXT.—:The management of lobular neoplasia (LN) found on core biopsy is controversial and ranges from obligatory surgical excision to clinical/imaging observation. OBJECTIVE.—:To determine if in cases of core needle biopsy yielding LN, quantification of normal and diseased terminal ductal lobular units (TDLUs) can ...

journal_title：Archives of pathology & laboratory medicine

authors： Holbrook AI,Hanley K,Jeffers C,Kang J,Cohen MA

更新日期：2019-05-01 00:00:00

abstract：:Revolutionary advances in technology have enhanced our understanding of the genetic changes that occur in cancer cells. This article summarizes some of the basic features of these techniques and describes their application to the identification of specific types of genetic alterations in cells. The emphasis is on thei...

journal_title：Archives of pathology & laboratory medicine

authors： Rowley JD,Aster JC,Sklar J

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:This report describes a new and improved "quick-hot Gram-chromotrope" staining technique that detects microsporidian spores in clinical specimens, such as stool, urine, saliva, nasopharyngeal fluid, and bronchoalveolar lavage samples, as well as in formalin-fixed and paraffin-embedded tissue sections. DESIGN...

journal_title：Archives of pathology & laboratory medicine

authors： Moura H,Schwartz DA,Bornay-Llinares F,Sodré FC,Wallace S,Visvesvara GS

更新日期：1997-08-01 00:00:00

abstract：:Malignant granular cell tumor is a rare neoplasm that has been reported to occur at various sites. Although there are no reliable histologic criteria to differentiate the benign from the malignant form of granular cell tumor, in many reported cases cellular pleomorphism and the presence of mitotic activity suggested a...

journal_title：Archives of pathology & laboratory medicine

authors： Parayno PP,August CZ

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVE:To describe the occurrence and significance of mucosal lymphangiectasia in gastric adenocarcinoma. DESIGN:One hundred consecutive gastrectomies for adenocarcinoma were reviewed, using 25 consecutive gastroscopically biopsied gastrectomy specimens with peptic ulcers as negative controls. SETTING:The specimen...

journal_title：Archives of pathology & laboratory medicine

authors： Mak KL,Hui PK,Chan WY,Leung KM

更新日期：1996-01-01 00:00:00

abstract：:Leydig cell tumor (LCT) is a rare tumor of the male testicular interstitium. This article provides an overview of the major pathologic manifestations of LCT of the testis; patient characteristics; clinical, radiologic, and laboratory features; prognosis; and management. LCTs of the testis are frequently hormonally act...

journal_title：Archives of pathology & laboratory medicine

authors： Al-Agha OM,Axiotis CA

更新日期：2007-02-01 00:00:00

abstract：:We studied a unique case of osteosarcoma of the testis. The tumor either originated from indifferent mesenchymal cells, or it represents a one-sided monomorphic development of a teratoma. ...

journal_title：Archives of pathology & laboratory medicine

authors： Mathew T,Prabhakaran K

更新日期：1981-01-01 00:00:00

abstract：CONTEXT:Antibody-mediated humoral rejection in kidney and heart allografts is well recognized and is often associated with poor outcome. C4d deposition in allograft biopsy specimens occurs at sites of antibody-mediated complement activation and has become one of the histopathologic criteria for diagnosis of humoral rej...

journal_title：Archives of pathology & laboratory medicine

authors： Troxell ML,Higgins JP,Kambham N

更新日期：2006-10-01 00:00:00

abstract：:We describe a 14-year-old boy with a solitary cavernous hemangioma in the proximal small intestine that caused recalcitrant iron deficiency anemia beginning at 3 years of age. After a number of attempts to ascertain the cause of the anemia were unsuccessful, the vascular tumor was ultimately diagnosed in the jejunum, ...

journal_title：Archives of pathology & laboratory medicine

authors： Boyle L,Lack EE

更新日期：1993-09-01 00:00:00

abstract：:Cystadenoma of the pancreas, principally a disease of adult women, was found in a female infant. This benign, nonfunctional tumor is usually amenable to surgery and a cure is to be expected after extirpation. The pathogenesis of this mass is unknown, but the finding of a cytomegalovirus infection in an excretory duct ...

journal_title：Archives of pathology & laboratory medicine

authors： Chang CH,Perrin EV,Hertzler J,Brough AJ

更新日期：1980-01-01 00:00:00

abstract：:We describe a young patient with no known family history of cancer who presented at 18 months with 2 advanced primary tumors, choroid plexus carcinoma and adrenal cortical carcinoma. Immunohistochemical studies demonstrated high levels of nuclear p53 protein expression in both tumors, as well as in the adjacent normal...

journal_title：Archives of pathology & laboratory medicine

authors： Wang L,Cornford ME

更新日期：2002-01-01 00:00:00

abstract：:In cases of obscure gastrointestinal bleeding, when a source for blood loss is not apparent from examination of the colon and upper gastrointestinal tract, the small bowel usually becomes the focus of investigation. A tumor with interesting pathologic features was found in a patient who presented with recurrent episod...

journal_title：Archives of pathology & laboratory medicine

authors： Sass DA,Chopra KB,Finkelstein SD,Schauer PR

更新日期：2004-02-01 00:00:00

abstract：:A 48-year-old Japanese woman died of multiple myeloma (lambda light-chain type) with chronic renal failure. Histological examination revealed deposition of a homogeneous substance and crystals in the kidneys and thyroid gland. The homogeneous substance was stained with Congo red after permanganate treatment but did no...

journal_title：Archives of pathology & laboratory medicine

authors： Hirota S,Miyamoto M,Kasugai T,Kitamura Y,Morimura Y

更新日期：1990-04-01 00:00:00

abstract：:Three fatal cases of heat stroke were encountered in the central New York area over a two-month period. Although in each instance one or more predisposing factors were identified, exertion clearly played a role in its development in only one case. In addition to laboratory and postmortem findings indicative of dysfunc...

journal_title：Archives of pathology & laboratory medicine

authors： Kim RC,Collins GH,Cho C,Ichikawa K,Givelber H

更新日期：1980-07-01 00:00:00

abstract：:Silicone, commonly used in cosmetic procedures owing to its presumed inertness, can yield serious sequelae including acute embolization and pneumonitis. Chronic pulmonary sequelae in response to silicone injection have not been previously described. We report a case of chronic progressive granulomatous pneumonitis in ...

journal_title：Archives of pathology & laboratory medicine

authors： Hariri LP,Gaissert HA,Brown R,Ciaranello A,Greene RE,Selig MK,Kradin RL

更新日期：2012-02-01 00:00:00

abstract：:We report the case of a patient treated with a combination of fludarabine and cyclophosphamide after suffering from B-cell chronic lymphocytic leukemia for 10 years. Three months after treatment, the patient presented with an unusual association, not previously reported in the literature: Richter syndrome (monotypic E...

journal_title：Archives of pathology & laboratory medicine

authors： Compérat E,Delmer A,Le Tourneau A,Molina TJ,Diebold J,Audouin J

更新日期：2006-08-01 00:00:00

abstract：:Clear cell sarcoma shares features with melanoma, but frequently shows EWSR1 rearrangements. It is an aggressive tumor typically occurring in the soft tissues of the extremities, with a gastrointestinal variant with less consistent melanocytic differentiation. It is extremely rare in the head and neck region, with no ...

journal_title：Archives of pathology & laboratory medicine

authors： Kraft S,Antonescu CR,Rosenberg AE,Deschler DG,Nielsen GP

更新日期：2013-11-01 00:00:00

abstract：:While the level of marrow reticulin may be a factor that is used when the presence of a hematologic disorder is being considered, to our knowledge no study has graded the amount of reticulin present in normal iliac bone marrow. Grading reticulin stains of bone biopsy specimens from 100 hematologically normal patients ...

journal_title：Archives of pathology & laboratory medicine

authors： Beckman EN,Brown AW Jr

更新日期：1990-12-01 00:00:00

abstract：:We reviewed 36 body fluid specimens from 18 patients with Hodgkin's disease (HD) to characterize the cytologic features of HD as seen in Wright-Giemsa (WG)-stained cytocentrifuge preparations, and to compare diagnostic agreement between WG- and Papanicolaou-stained samples. Slides were examined independently by two pa...

journal_title：Archives of pathology & laboratory medicine

authors： Wilson MS,Theil KS,Goodwin RA,Brandt JT

更新日期：1988-06-01 00:00:00

abstract：CONTEXT:A Treatise on Pathological Anatomy, published in 1829 by William E. Horner, is the first American textbook on pathology. Several articles have been written on Horner, but they do not evaluate the role that the knowledge he recorded played on the intellectual origin of the discipline of pathology in America. Onl...

journal_title：Archives of pathology & laboratory medicine

authors： Quinonez G,McLendon WW

更新日期：2011-12-01 00:00:00

abstract：CONTEXT:The differential diagnosis of eosinophilic renal tumors can be difficult by light microscopy. In particular, chromophobe renal cell carcinoma (RCC) is difficult to distinguish from oncocytoma. This differential diagnosis is important because chromophobe RCC is malignant, whereas oncocytoma is benign. Furthermor...

journal_title：Archives of pathology & laboratory medicine

authors： Hornsby CD,Cohen C,Amin MB,Picken MM,Lawson D,Yin-Goen Q,Young AN

更新日期：2007-10-01 00:00:00

abstract：:A 55-year-old woman developed symptoms suggestive of hepatitis 12 weeks after first receiving methyldopa for hypertension. Liver biopsy showed chronic aggressive hepatitis with subacute hepatic necrosis. Methyldopa was discontinued, but after exhibiting transient clinical improvement, the patient's condition progressi...

journal_title：Archives of pathology & laboratory medicine

authors： Thomas E,Bhuta S,Rosenthal WS

更新日期：1976-03-01 00:00:00

abstract：CONTEXT:Estrogen receptor and progesterone receptor status is assessed on all newly diagnosed, invasive breast carcinomas and in recurrences to determine patient eligibility for hormonal therapy, but 10% to 20% of estrogen receptor and progesterone receptor test results are discordant when tested in multiple laboratori...

journal_title：Archives of pathology & laboratory medicine

authors： Fitzgibbons PL,Murphy DA,Hammond ME,Allred DC,Valenstein PN

更新日期：2010-06-01 00:00:00

abstract：CONTEXT:Our understanding of molecular events in the pathogenesis of hematologic malignancies has evolved substantially. The research data gathered in the past 3 decades have led to the definition of neoplastic disorders based on specific genetic and molecular alterations, which is reflected in the current World Health...

journal_title：Archives of pathology & laboratory medicine

authors： Pozdnyakova O,Kutok JL,Rodig SJ

更新日期：2012-05-01 00:00:00

abstract：CONTEXT:Immunohistochemistry has become an indispensable ancillary study in the identification and classification of undifferentiated neoplasms/tumors of uncertain origin. The diagnostic accuracy has significantly improved because of the continuous discoveries of tissue-specific biomarkers and the development of effect...

journal_title：Archives of pathology & laboratory medicine

authors： Lin F,Liu H

更新日期：2014-12-01 00:00:00

abstract：:To understand better the intracellular iron distribution and metabolic consequences of chronic hepatic iron overload, rats were given large doses of iron dextran or ferric citrate intraperitoneally. They accumulated large quantities of iron within Kupffer cells and hepatocytes. The relative subcellular iron distributi...

journal_title：Archives of pathology & laboratory medicine

authors： Bonkowsky HL,Carpenter SJ,Healey JF

更新日期：1979-01-01 00:00:00

abstract：:A necrotizing retinopathy following a vesicular cutaneous eruption in the distribution of the right trigeminal nerve developed in a patient who had been receiving systemic corticosteroid therapy one week prior to the onset of herpes zoster ophthalmicus. Seven weeks after the herpetic symptoms began, the patient died o...

journal_title：Archives of pathology & laboratory medicine

authors： Schwartz JN,Cashwell F,Hawkins HK,Klintworth GK

更新日期：1976-07-01 00:00:00

abstract：:This study was performed to evaluate the correlation between HER-2/neu gene expression and DNA ploidy patterns. Forty-five cases of breast-cancer were analyzed. Immunohistochemical staining of HER-2/neu protein on frozen sections was used to detect the HER-2/neu protein, and the Feulgen DNA staining method was used to...

journal_title：Archives of pathology & laboratory medicine

authors： Bacus SS,Bacus JW,Slamon DJ,Press MF

更新日期：1990-02-01 00:00:00

abstract：:A number of classes of endogenous antibodies, including heterophile, rheumatoid factor, and autoantibodies, can interfere with immunoassay measurements of many different analytes. Heterophile and rheumatoid factor antibody interferences have been described previously for the AxSYM cardiac troponin I assay. Several com...

journal_title：Archives of pathology & laboratory medicine

authors： Knoblock RJ,Lehman CM,Smith RA,Apple FS,Roberts WL

更新日期：2002-05-01 00:00:00

abstract：CONTEXT:The inhibition of oncogenic kinase signaling is a successful strategy to treat both hematologic and solid malignancies. Patients with chronic myelogenous leukemia, lung adenocarcinoma, renal cell carcinoma, and gastrointestinal stromal tumors are experiencing tremendous clinical benefits from targeted therapies...

journal_title：Archives of pathology & laboratory medicine

authors： Marrari A,Wagner AJ,Hornick JL

更新日期：2012-05-01 00:00:00