Emerging targeted therapies for lymphoid malignancies.

abstract：:Previous immunohistochemical studies of cardiac myxomas are few in number, limited in scope and, in part, discrepant. We studied the immunoreactivity of five cardiac myxomas for factor VIII-related antigen, Ulex europaeus agglutinin I, smooth-muscle myosin, alpha 1-antitrypsin, and alpha 1-antichymotrypsin. Positive s...

journal_title：Archives of pathology & laboratory medicine

authors： Landon G,Ordóñez NG,Guarda LA

更新日期：1986-02-01 00:00:00

abstract：CONTEXT:The College of American Pathologists (CAP) Human Papillomavirus (High-Risk) Survey for Cytopathology and Other Laboratories (CHPV) meets the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) requirements for 5 proficiency testing challenges analyzed 3 times per year. This study reports laboratory pe...

journal_title：Archives of pathology & laboratory medicine

authors： Moriarty AT,Bentz JS,Winkler B,Fischer AH,Laucirica R,Souers RJ,Thomas N,Zhao C

更新日期：2013-05-01 00:00:00

abstract：:The College of American Pathologists' enzyme survey permits the evaluation of the quality of enzyme analyses in clinical laboratories. Animal source enzymes for lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, and creatine kinase are satisfactory as supplements for enzyme survey serum, sinc...

journal_title：Archives of pathology & laboratory medicine

authors： Lott JA,Tholen DW,Massion CG

更新日期：1984-12-01 00:00:00

abstract：CONTEXT:Deletion of the short arm of chromosome 3 (3p deletion) is a cytogenetic abnormality generally associated with clear cell renal cell carcinoma, the most aggressive form of renal epithelial tumor. OBJECTIVE:To cytogenetically characterize 24 renal tumors in order to check the incidence and the type of 3p deleti...

journal_title：Archives of pathology & laboratory medicine

authors： Gayrard N,Cacheux V,Iborra F,Mourad G,Argilés A

更新日期：2008-06-01 00:00:00

abstract：:Therapeutic drugs are not endogenous compounds. Therefore, differing reactivities between proficiency testing and patient samples have potential mechanisms beyond those attributable to alterations of the serum protein base, stabilizing materials, and other manufacturing components. The therapeutic drug monitoring prof...

journal_title：Archives of pathology & laboratory medicine

authors： Witte DL

更新日期：1993-04-01 00:00:00

abstract：CONTEXT:-The data in College of American Pathologists cancer protocols have to be presented effectively to health care providers. There is no consensus on the format of those protocols, resulting in various designs among pathologists. Cancer protocols are independently created by site-specific experts, so there is inco...

journal_title：Archives of pathology & laboratory medicine

authors： Strickland-Marmol LB,Muro-Cacho CA,Barnett SD,Banas MR,Foulis PR

更新日期：2016-06-01 00:00:00

abstract：:We describe a rare case of a neuroendocrine carcinoma of the ovary in a 22-year-old woman who presented with abdominal pain and a pelvic mass. Exploratory laparotomy revealed a right ovarian tumor weighing 2100 g. A right salpingo-oophorectomy and an appendectomy were performed. There was no evidence intraoperatively ...

journal_title：Archives of pathology & laboratory medicine

authors： Khurana KK,Tornos C,Silva EG

更新日期：1994-10-01 00:00:00

abstract：:We studied a unique case of osteosarcoma of the testis. The tumor either originated from indifferent mesenchymal cells, or it represents a one-sided monomorphic development of a teratoma. ...

journal_title：Archives of pathology & laboratory medicine

authors： Mathew T,Prabhakaran K

更新日期：1981-01-01 00:00:00

abstract：:Bowen disease is a variant of squamous cell carcinoma in situ. In some cases a pagetoid growth pattern can be observed with cytologically atypical clear cells arranged singly and in nests. The differential diagnosis of pagetoid Bowen disease includes primarily Paget disease and malignant melanoma in situ, as well as o...

journal_title：Archives of pathology & laboratory medicine

authors： Williamson JD,Colome MI,Sahin A,Ayala AG,Medeiros LJ

更新日期：2000-03-01 00:00:00

abstract：:Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females. Angiomyolipoma occurs most commonly in the kidneys. The liver represents the second most frequent site of involvement. Hepatic angiomyolipomas are composed of varying amounts of s...

journal_title：Archives of pathology & laboratory medicine

authors： Petrolla AA,Xin W

更新日期：2008-10-01 00:00:00

abstract：:A large mucinous cystic neoplasm of the pancreas was found that showed a remarkably high carcinoembryonic antigen (CEA) level in cyst content. Staining for CEA was also detected in the lining epithelium. These findings indicate that columnar epithelial cells secrete CEA that accumulates in the cyst. We suggest that a ...

journal_title：Archives of pathology & laboratory medicine

authors： Yu HC,Shetty J

更新日期：1985-04-01 00:00:00

abstract：:von Hippel-Lindau (VHL) disease is an autosomal dominant disorder caused by heterozygous mutations in the VHL tumor suppressor gene that is characterized by the occurrence of multiple endocrine and nonendocrine lesions. This review focuses on the endocrine manifestations of VHL disease. Pancreatic neuroendocrine proli...

journal_title：Archives of pathology & laboratory medicine

authors： Cassol C,Mete O

更新日期：2015-02-01 00:00:00

abstract：CONTEXT.—:Ossifying fibromyxoid tumor (OFMT) is a rare, slow-growing mesenchymal neoplasm of uncertain histogenesis with intermediate malignant potential. OBJECTIVE.—:To highlight the most important diagnostic features, including morphologic, immunohistochemical, and molecular findings; to provide comparisons to other...

journal_title：Archives of pathology & laboratory medicine

authors： Carter CS,Patel RM

更新日期：2019-12-01 00:00:00

abstract：:Embolic cerebellar tissue was observed microscopically in the pulmonary and coronary arteries of a full-term male infant who died 1 hour after forceps delivery. Although embolization of brain tissue has been well documented after severe head trauma in adults and children, to our knowledge only 17 cases associated with...

journal_title：Archives of pathology & laboratory medicine

authors： Hauck AJ,Bambara JF,Edwards WD

更新日期：1990-02-01 00:00:00

abstract：:Endocrine manifestations are rarely observed in bladder urothelial neoplasia. To our knowledge, only 11 cases of choriocarcinoma have been reported in this site, and recently the production of beta-human chorionic gonadotropin has been demonstrated in these tumors by applying the immunoperoxidase technique. Of 104 tra...

journal_title：Archives of pathology & laboratory medicine

authors： Shah VM,Newman J,Crocker J,Chapple CR,Collard MJ,O'Brien JM,Considine J

更新日期：1986-02-01 00:00:00

abstract：CONTEXT:Carcinoid tumor metastatic to the breast is uncommon and can closely mimic a mammary carcinoma. The differentiation of metastatic carcinoid tumor from primary breast tumor is important, however, owing to different clinical management and prognosis. OBJECTIVE:The purpose of this study was to describe 2 patients...

journal_title：Archives of pathology & laboratory medicine

authors： Mosunjac MB,Kochhar R,Mosunjac MI,Lau SK

更新日期：2004-03-01 00:00:00

abstract：:The concept of injury as a mechanism leading to atherosclerosis has been fostered by numerous studies of initiating factors and by observation of the response of cardiovascular connective tissue, ie, cellular and extracellular matrix components. Carbohydrate-protein macromolecules of the extracellular matrix are a com...

journal_title：Archives of pathology & laboratory medicine

authors： Berenson GS,Radhakrishnamurthy B,Srinivasan SR,Vijayagopal P,Dalferes ER Jr

更新日期：1988-10-01 00:00:00

abstract：:We studied a case of Sturge-Weber syndrome in a 66-year-old woman, who displayed associated angiomas of the thyroid gland and choroid plexi and leptomeningeal melanosis. These findings are discussed in light of the proposed pathogenesis of the syndrome and its relationship to the other neuroectodermal dysplasias. ...

journal_title：Archives of pathology & laboratory medicine

authors： Bentz MS,Towfighi J,Greenwood S,Zaino R

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVE:To present recent advances in the use of molecular markers in diagnosis, in prognosis, in early detection, in novel therapies, and in understanding the molecular pathogenesis of colorectal neoplasia. DATA AND LITERATURE SOURCES:A review of studies of molecular markers in colorectal neoplasia, published in En...

journal_title：Archives of pathology & laboratory medicine

authors： Grizzle WE,Manne U,Jhala NC,Weiss HL

更新日期：2001-01-01 00:00:00

abstract：:The increasing interest in geriatric medicine demands an understanding of aging in human tissues. The changes in the human heart are an important aspect of this understanding because cardiovascular diseases are a leading medical problem in the elderly. The published data about age-related changes in the human myocardi...

journal_title：Archives of pathology & laboratory medicine

authors： Klima M,Burns TR,Chopra A

更新日期：1990-09-01 00:00:00

abstract：:Toxoplasmosis is a common opportunistic pathogen in patients with acquired immunodeficiency syndrome (AIDS). It usually presents with ocular, central nervous system, or pulmonary disease. Gastric toxoplasmosis is uncommon in AIDS patients, especially in the absence of central nervous system manifestations. In the few ...

journal_title：Archives of pathology & laboratory medicine

authors： Ganji M,Tan A,Maitar MI,Weldon-Linne CM,Weisenberg E,Rhone DP

更新日期：2003-06-01 00:00:00

abstract：:Yeast forms of Blastomyces dermatitidis typically range from 8 to 20 microm in largest diameter. We report a rare case of primary pulmonary blastomycosis with an unusual morphology, in which we found significant numbers of large yeast forms ranging from 30 to 35 microm in diameter. To our knowledge, this is only the s...

journal_title：Archives of pathology & laboratory medicine

authors： Hussain Z,Martin A,Youngberg GA

更新日期：2001-05-01 00:00:00

abstract：:We report a primary intraocular T-cell-rich large B-cell lymphoma in a 57-year-old woman who underwent 3 diagnostic vitrectomies for a presumed diagnosis of panuveitis. She developed no light perception in the left eye and underwent enucleation. Histopathologic and immunohistochemical studies on the enucleated globe d...

journal_title：Archives of pathology & laboratory medicine

authors： Cummings TJ,Stenzel TT,Klintworth G,Jaffe GJ

更新日期：2005-08-01 00:00:00

abstract：CONTEXT:Since 1988, the College of American Pathologists has been offering materials for calibration verification coupled with the surveys for linearity, called the linearity (LN) surveys. OBJECTIVE:To determine whether successful completion of the College of American Pathologists LN surveys provides a benefit in term...

journal_title：Archives of pathology & laboratory medicine

authors： Kroll MH,Styer PE,Vasquez DA

更新日期：2004-05-01 00:00:00

abstract：:Fibrolamellar carcinoma is a rare primary hepatocellular malignancy arising in noncirrhotic livers of young individuals. Patients commonly present with a large solitary liver mass and nonspecific symptoms. Characteristic histologic features include large polygonal cells with oncocytic cytoplasm and prominent nucleoli ...

journal_title：Archives of pathology & laboratory medicine

authors： Lin CC,Yang HM

更新日期：2018-09-01 00:00:00

abstract：:Early proliferative coronary atherosclerosis was produced in swine by feeding them a high-fat, high-cholesterol diet for 17 months, at which time one group of animals was killed (reference group), while the remainder was transferred for 12 months to a moderate diet that resulted in serum cholesterol levels of about 19...

journal_title：Archives of pathology & laboratory medicine

authors： Jarmolych J,Daoud AS,Fritz KE,Augustyn JM,Singh JK,Kim DN

更新日期：1978-06-01 00:00:00

abstract：:A patient with a 100-g thymolipoma and myasthenia gravis experienced marked improvement in neuromuscular symptoms following removal of the tumor. Although 60 examples of thymolipoma have been reported, we believe that this is the first example of this tumor associated with myasthenia gravis. The clinical, radiologic, ...

journal_title：Archives of pathology & laboratory medicine

authors： Reintgen D,Fetter BF,Roses A,McCarty KS Jr

更新日期：1978-09-01 00:00:00

abstract：:Context.-We investigated expression of the adhesion molecule CD31 in sinus histiocytosis with massive lymphadenopathy (SHML) and Langerhans cell histiocytosis (LCH) because (1) SHML and LCH cells express a variety of cellular adhesion molecules and (2) SHML has been characterized as a reactive histiocytic proliferatio...

journal_title：Archives of pathology & laboratory medicine

authors： Slone SP,Fleming DR,Buchino JJ

更新日期：2003-03-01 00:00:00

abstract：CONTEXT:Accurate categorization of uterine smooth muscle neoplasms by light microscopic examination is difficult. Multiple classification schemes have been proposed based on mitotic rate, nuclear atypia, and the presence or absence of necrosis. None of these classification systems has been entirely successful. Multiple...

journal_title：Archives of pathology & laboratory medicine

authors： Layfield LJ,Liu K,Dodge R,Barsky SH

更新日期：2000-02-01 00:00:00

abstract：:Tumoral calcinosis is a rare ectopic calcification syndrome characterized by irregular soft tissue masses originally described as being found mainly in large joints. We report 3 cases of tumoral calcinosis that occurred in unusual locations, the metacarpophalageal and proximal interphalangeal joints of the hand. The p...

journal_title：Archives of pathology & laboratory medicine

authors： Kim HS,Suh JS,Kim YH,Park SH

更新日期：2006-04-01 00:00:00