Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features.

Abstract:

:The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes to fully developed dermatopathic lymphadenitis. Twenty-three lymph node biopsies previously interpreted as diagnostic of dermatopathic lymphadenitis were reviewed. Only nine of these showed the fully developed dermatopathic lymphadenitis. Only one of these patients had a dermatitis. Our conclusions are that the presence of dermatopathic lymphadenitis does not mean that the patient has concomitant skin disease, and that axillary lymph nodes from patients without skin disease manifest a spectrum of dermatopathic lymphadenitis-like histologic features. Dermatopathic lymphadenitis may represent one end of a normally occurring histologic spectrum that may be found in the absence of a dermatitis.

journal_name

Arch Pathol Lab Med

authors

Gould E,Porto R,Albores-Saavedra J,Ibe MJ

subject

Has Abstract

pub_date

1988-11-01 00:00:00

pages

1145-50

issue

11

eissn

0003-9985

issn

1543-2165

journal_volume

112

pub_type

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