Intraosseous benign notochordal cell tumor.

Abstract:

:Intraosseous benign notochordal cell tumor is a presumably benign, intravertebral lesion of notochord origin, which can be found incidentally on removal of the vertebra for unrelated lesions or during an autopsy. The notion of a larger benign notochordal cell tumor that is macroscopic, occasionally symptomatic, and seen radiologically was recently introduced, and described as giant vertebral notochordal rest, giant notochordal hamartoma of intraosseous origin, and benign chordoma . Because of the location, size, and similar histologic and immunohistochemical characteristics, larger benign notochordal cell tumors are easily misdiagnosed as the malignant notochord-type of tumor/chordoma, with critical implications. In this review, we attempt to shed light on the major differences between benign notochordal cell tumors and chordoma and other related notochord lesions, such as notochordal vestiges of the intervertebral disk and ecchordosis physaliphora.

journal_name

Arch Pathol Lab Med

authors

Amer HZ,Hameed M

doi

10.1043/1543-2165-134.2.283

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

283-8

issue

2

eissn

0003-9985

issn

1543-2165

pii

10.1043/1543-2165-134.2.283

journal_volume

134

pub_type

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