当前位置： SCI文献检索 > KIDNEY INTERNATIONAL期刊下所有文献 > Enteral nutrition in patients with acute renal failure.

Enteral nutrition in patients with acute renal failure.

Abstract：

BACKGROUND:Systematic studies on safety and efficacy of enteral nutrition in patients with acute renal failure (ARF) are lacking. METHODS:We studied enteral nutrition-related complications and adequacy of nutrient administration during 2525 days of artificial nutrition in 247 consecutive patients fed exclusively by the enteral route: 65 had normal renal function, 68 had ARF not requiring renal replacement therapy, and 114 required renal replacement therapy. RESULTS:No difference was found in gastrointestinal or mechanical complications between ARF patients and patients with normal renal function, except for high gastric residual volumes, which occurred in 3.1% of patients with normal renal function, 7.3% of patients with ARF not requiring renal replacement therapy, 13.2% of patients with ARF on renal replacement therapy (P= 0.02 for trend), and for nasogastric tube obstruction: 0.0%, 5.9%, 14%, respectively (P < 0.001). Gastrointestinal complications were the most frequent cause of suboptimal delivery; the ratio of administered to prescribed daily volume was well above 90% in all the three groups. Definitive withdrawal of enteral nutrition due to complications was documented in 6.1%, 13.2%. and 14.9% of patients, respectively (P= 0.09 for trend). At regimen, mean delivered nonprotein calories were 19.8 kcal/kg (SD 4.6), 22.6 kcal/kg (8.4), 23.4 kcal/kg (6.5); protein intake was 0.92 g/kg (0.21), 0.87 g/kg (0.25), and 0.92 g/kg (0.21), the latter value being below that currently recommended for ARF patients on renal replacement therapy. Median fluid intake with enteral nutrition was 1440 mL (range 720 to 1960), 1200 (720 to 2400), and 960 (360 to 1920). CONCLUSION:Enteral nutrition is a safe and effective nutritional technique to deliver artificial nutrition in ARF patients. Parenteral amino acid supplementation may be required, especially in patients with ARF needing renal replacement therapy.

journal_name

Kidney Int

journal_title

Kidney international

authors

Fiaccadori E,Maggiore U,Giacosa R,Rotelli C,Picetti E,Sagripanti S,Melfa L,Meschi T,Borghi L,Cabassi A

doi

10.1111/j.1523-1755.2004.00459.x

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

999-1008

issue

eissn

0085-2538

issn

1523-1755

pii

S0085-2538(15)49793-5

journal_volume

pub_type

杂志文章

在线工具

Enteral nutrition in patients with acute renal failure.