Formaldehyde kinetics and bacteriology in dialyzers.

abstract：:The adaptation of erythropoietin production to oxygen supply is determined by the abundance of hypoxia-inducible factor (HIF), a regulation that is induced by a prolyl hydroxylase. To identify cells that express HIF subunits (HIF-1alpha and HIF-2alpha) and erythropoietin, we treated Sprague-Dawley rats with the prolyl...

journal_title：Kidney international

authors： Paliege A,Rosenberger C,Bondke A,Sciesielski L,Shina A,Heyman SN,Flippin LA,Arend M,Klaus SJ,Bachmann S

更新日期：2010-02-01 00:00:00

abstract：:Primary hyperoxaluria type I (PH I) is a congenital error of metabolism that can be manifested by an increased oxalate production, and ultimately result in kidney failure. After a combined liver/kidney transplantation, children with PH I have persistent excretion of oxalate that causes crystal formation in the urinary...

journal_title：Kidney international

authors： Jouvet P,Priqueler L,Gagnadoux MF,Jan D,Beringer A,Lacaille F,Revillon Y,Broyer M,Daudon M

更新日期：1998-05-01 00:00:00

abstract：:Thrombotic microangiopathy (TMA) is a poorly recognized cause of collapsing glomerulopathy. The frequency and significance of collapsing glomerulopathy associated with renal TMA have not been specifically studied in native kidney biopsy specimens. Here we retrospectively documented clinicopathologic features of 53 pat...

journal_title：Kidney international

authors： Buob D,Decambron M,Gnemmi V,Frimat M,Hoffmann M,Azar R,Gheerbrant JD,Guincestre T,Noël C,Copin MC,Glowacki F

更新日期：2016-12-01 00:00:00

abstract：:The processes of growth and remodeling that characterize growing bone are vulnerable to the biochemical effects of uremia. These processes are affected by the alterations in vitamin D metabolism and hyperparathyroidism that commonly occur with chronic renal insufficiency. Uremia interferes with cartilaginous developme...

journal_title：Kidney international

authors： Avioli LV

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Population-genetic studies investigating genetic polymorphisms of Mendelian inheritance should always test whether the measured genotype frequencies deviate from the expected one. For this purpose Hardy-Weinberg (HW) criteria are generally used. If genotype distribution of control population misses HW equili...

journal_title：Kidney international

authors： Kocsis I,Györffy B,Németh E,Vásárhelyi B

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Mesangial immunoglobulin A (IgA) deposition is incidentally encountered in asymptomatic individuals, but its precise frequency and significance had not been clarified. The background of the latent IgA deposition is related to the epidemiology and pathogenesis of IgA nephropathy. METHODS:Zero-hour allograft ...

journal_title：Kidney international

authors： Suzuki K,Honda K,Tanabe K,Toma H,Nihei H,Yamaguchi Y

更新日期：2003-06-01 00:00:00

abstract：:Renal dysfunction is a common and serious complication in multiple myeloma (MM) patients. Renal proximal tubule injury is characteristic in MM, and may result in disturbed renal handling of various vitamins. The abnormal excretion of vitamins in urine may result in their low serum levels. The goal of this study was to...

journal_title：Kidney international

authors： Gavrilov V,Yermiahu T,Gorodischer R

更新日期：2006-01-01 00:00:00

abstract：:Diabetes is a major cause of chronic kidney disease, and oral antidiabetic drugs are the mainstay of therapy for most patients with Type 2 diabetes. Here we evaluated their role on renal outcomes by using a national Veterans Administration database to assemble a retrospective cohort of 93,577 diabetic patients who fil...

journal_title：Kidney international

authors： Hung AM,Roumie CL,Greevy RA,Liu X,Grijalva CG,Murff HJ,Ikizler TA,Griffin MR

更新日期：2012-04-01 00:00:00

abstract：:In this retrospective study, we analyzed clinical laboratory, and pathologic variables to determine their value in predicting survival and survival free of renal failure for 170 consecutive patients with idiopathic renal vasculitis and glomerulonephritis evaluated during a 15 year period. Of the 170 patients, 108 had ...

journal_title：Kidney international

authors： Wilkowski MJ,Velosa JA,Holley KE,Offord KP,Chu CP,Torres VE,McCarthy JT,Donadio JV Jr,Wagoner RD

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Our preliminary studies indicate that chronic caffeine consumption has adverse renal effects in nephropathy associated with high blood pressure and insulin resistance. The purpose of this study was to investigate the effects of early (beginning at 8 weeks of age) and long-term (30 weeks) caffeine treatment (...

journal_title：Kidney international

authors： Tofovic SP,Kost CK Jr,Jackson EK,Bastacky SI

更新日期：2002-04-01 00:00:00

abstract：:Chronic balance studies were performed in six adrenalectomized patients to investigate the renal and systemic acid-base consequences of mineralocorticoid deficiency in the absence of either glucocorticoid deficiency or parenchymal renal disease. Constant glucocorticoid replacement was provided with dexamethasone, 750 ...

journal_title：Kidney international

authors： Sebastian A,Sutton JM,Hulter HN,Schambelan M,Poler SM

更新日期：1980-12-01 00:00:00

abstract：:Quartan malarial infection causes an immune complex nephritis in some individuals, which, once established, is sustained by mechanisms not yet fully explained, but which probably involve autoimmune processes. The presenting clinical and biochemical findings of the quartan malarial nephrotic syndrome are similar to tho...

journal_title：Kidney international

authors： Hendrickse RG,Adeniyi A

更新日期：1979-07-01 00:00:00

abstract：:To test the contribution of bicarbonate (Bi) to hemodynamic stability during hemodialysis (HD), we compared the effects of ultrafiltration dialysis with bicarbonate and with acetate under conditions of high-sodium (141 mEq/liter) and low-sodium (130 mEq/liter) dialysate concentrations in 12 stable HD patients. Group 1...

journal_title：Kidney international

authors： Velez RL,Woodard TD,Henrich WL

更新日期：1984-07-01 00:00:00

abstract：:Risk factors for disease states are rigorously defined. This analysis considers the definition of a risk factor as applied to the question of whether the serum phosphorus level is a risk factor for cardiovascular disease. Observational studies strongly suggest that phosphorus is associated with cardiovascular risk, an...

journal_title：Kidney international

authors： Hruska K,Mathew S,Lund R,Fang Y,Sugatani T

更新日期：2011-04-01 00:00:00

abstract：:Obesity has been suggested to have a detrimental impact on kidney structure and function, leading to focal glomerulosclerosis and hypertension. It is also associated with hyperleptinemia and elevated renal sympathetic nerve activity. Prenatal undernutrition promotes postnatal obesity, hypertension, and an altered rena...

journal_title：Kidney international

authors： Williams PJ,Kurlak LO,Perkins AC,Budge H,Stephenson T,Keisler D,Symonds ME,Gardner DS

更新日期：2007-08-01 00:00:00

abstract：:Indomethacin has been used to lower proteinuria in human glomerular diseases with controversial results. The mechanism of indomethacin beneficial effects has not been established. A possible explanation is that indomethacin reduces proteinuria by inhibiting the synthesis of renal prostaglandins (PGs); however, appropr...

journal_title：Kidney international

authors： Zoja C,Benigni A,Verroust P,Ronco P,Bertani T,Remuzzi G

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:This study examined the effects of stent placement for renal artery stenosis on the function of treated and contralateral kidneys. METHODS:Eighteen patients who underwent stent placement for unilateral renal artery stenosis presenting with hypertension and/or renal failure were studied before angiography an...

journal_title：Kidney international

authors： Leertouwer TC,Derkx FH,Pattynama PM,Deinum J,van Dijk LC,Schalekamp MA

更新日期：2002-08-01 00:00:00

abstract：:Emerging evidence of crosstalk between glomerular cells in pathological settings provides opportunities for novel therapeutic discovery. Here we investigated underlying mechanisms of early events leading to filtration barrier defects of podocyte and glomerular endothelial cell crosstalk in the mouse models of primary ...

journal_title：Kidney international

authors： Ebefors K,Wiener RJ,Yu L,Azeloglu EU,Yi Z,Jia F,Zhang W,Baron MH,He JC,Haraldsson B,Daehn I

更新日期：2019-10-01 00:00:00

abstract：:Low-protein diets (LPD) increase insulin-mediated glucose disposal in chronic renal failure (CRF), but the fate of the better utilized glucose and the effect on energy production rate are unknown. Using a two-step (1 and 5 mU x kg(-1) x min(-1)) euglycemic hyperinsulinemic clamp combined with indirect calorimetry, we ...

journal_title：Kidney international

authors： Rigalleau V,Combe C,Blanchetier V,Aubertin J,Aparicio M,Gin H

更新日期：1997-04-01 00:00:00

abstract：:Podocytes are highly differentiated cells that play an important role in maintaining glomerular filtration barrier integrity; a function regulated by small GTPase proteins of the Rho family. To investigate the role of Rho A in podocyte biology, we created transgenic mice expressing doxycycline-inducible constitutively...

journal_title：Kidney international

authors： Wang L,Ellis MJ,Gomez JA,Eisner W,Fennell W,Howell DN,Ruiz P,Fields TA,Spurney RF

更新日期：2012-06-01 00:00:00

abstract：:Antibody-mediated rejection represents the first cause of graft loss in renal transplant recipients, and it is imperative to identify appropriate tools to enable risk stratification of such patients. Lately, the usefulness of measuring complement-binding anti-human leukocyte antigen (HLA) donor-specific antibodies (DS...

journal_title：Kidney international

authors： Cozzi E,Biancone L

更新日期：2018-10-01 00:00:00

abstract：:Residual renal function is a major survival determinant for peritoneal dialysis patients. Hypovolemia can cause acute kidney injury and loss of residual renal function, and it has been suggested that patients receiving peritoneal dialysis should preferably be maintained hypervolemic to preserve residual renal function...

journal_title：Kidney international

authors： McCafferty K,Fan S,Davenport A

更新日期：2014-01-01 00:00:00

abstract：:The relative importance of sarcopenia and its individual components as independent predictors of mortality in the dialysis population has not been determined. We estimated whole-body muscle mass using pre-dialysis bioimpedance spectroscopy measurements in 645 ACTIVE/ADIPOSE-enrolled prevalent hemodialysis patients fro...

journal_title：Kidney international

authors： Kittiskulnam P,Chertow GM,Carrero JJ,Delgado C,Kaysen GA,Johansen KL

更新日期：2017-07-01 00:00:00

abstract：:Atherogenic lipoproteins and reactive oxygen species stimulate renin release from isolated juxtaglomerular (JG) cells. Here we assessed whether stimulation of renin release is mediated by formation of superoxide anion (O2-), and whether the effects of oxidized lipoproteins, like in many other biological systems, can b...

journal_title：Kidney international

authors： Galle J,Heinloth A,Schwedler S,Wanner C

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Vascular access failure is the main cause of morbidity in hemodialysis. Venous stenosis and subsequent thrombosis, as the result of intimal hyperplasia, is the major cause of vascular access failure. Intimal hyperplasia of the arteriovenous fistula (AVF) closely resembles the main histopathologic feature of ...

journal_title：Kidney international

authors： Grandaliano G,Teutonico A,Allegretti A,Losappio R,Mancini A,Gesualdo L,Schena FP,Pertosa G

更新日期：2003-08-01 00:00:00

abstract：:Kallistatin is a serine protease inhibitor with anti-inflammatory, anti-angiogenic, and anti-oxidative properties. Since oxidative stress plays a critical role in the pathogenesis of diabetic nephropathy, we studied the effect and mechanisms of action of kallistatin superinduction. Using ultrasound-microbubble-mediate...

journal_title：Kidney international

authors： Yiu WH,Wong DW,Wu HJ,Li RX,Yam I,Chan LY,Leung JC,Lan HY,Lai KN,Tang SC

更新日期：2016-02-01 00:00:00

abstract：:A genome-wide association scan of the Genetics of Kidneys in Diabetes (GoKinD) collections identified four novel susceptibility loci, located on chromosomes 7p14.3, 9q21.32, 11p15.4, and 13q33.3 associated with type 1 diabetic nephropathy. A recent evaluation of these loci in Japanese patients with type 2 diabetes sup...

journal_title：Kidney international

authors： Pezzolesi MG,Poznik GD,Skupien J,Smiles AM,Mychaleckyj JC,Rich SS,Warram JH,Krolewski AS

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Nephrotic syndrome is associated with abnormal lipoprotein metabolism and increased risk of coronary heart disease. Endothelial dysfunction, an early phase of atherogenesis that manifests as impaired flow-mediated dilation (FMD) of the peripheral circulation, may link these associations. METHODS:We examined...

journal_title：Kidney international

authors： Watts GF,Herrmann S,Dogra GK,Playford DA,Best JD,Thomas MA,Irish A

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Both high glucose (HG) and angiotensin II (Ang II) causes glomerular mesangial cell (GMC) growth and increased synthesis of matrix proteins like collagen IV contributing to diabetic nephropathy. We have recently found that exposure of vascular smooth muscle cells to HG augments the Ang II activation of the g...

journal_title：Kidney international

authors： Amiri F,Shaw S,Wang X,Tang J,Waller JL,Eaton DC,Marrero MB

更新日期：2002-05-01 00:00:00

abstract：:Vitamin D deficiency is common in patients with chronic kidney disease after renal transplantation. Vitamin D, essential for mineral and bone metabolism, also has myriad beneficial autocrine effects on intact immune responses and defense against infection, as well as suppression of malignant changes. Supplementation w...

journal_title：Kidney international

authors： Levi R,Silver J

更新日期：2009-03-01 00:00:00