The role of hyperparathyroidism, erythropoietin therapy, and CMV infection in the failure of arteriovenous fistula in hemodialysis.

abstract：:The members of the matrix metalloproteinase gene family play critical roles in numerous physiologic events, including cellular migration, tissue remodeling in wound healing and development, as well as in the evolution of the inflammatory process. The 72 kDa gelatinase A (formerly denoted 72 kDa Type IV collagenase) is...

journal_title：Kidney international

authors： Turck J,Pollock AS,Lovett DH

更新日期：1997-05-01 00:00:00

abstract：UNLABELLED:Inhibition of pressure natriuresis in mice lacking the AT2 receptor. BACKGROUND:Angiotensin II type 2 (AT2) receptor knockout mice have higher blood pressures than wild-type mice; however, the hypertension is imperfectly defined. We tested the hypothesis that renal mechanisms could be contributory. METHODS...

journal_title：Kidney international

authors： Gross V,Schunck WH,Honeck H,Milia AF,Kärgel E,Walther T,Bader M,Inagami T,Schneider W,Luft FC

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Microarray technology is a powerful tool that can probe the molecular pathogenesis of renal injury. In this present study microarray analysis was used to monitor serial changes in the renal transcriptome of a rat model of mesangial proliferative glomerulonephritis. Administration of anti-Thy1 antibody result...

journal_title：Kidney international

authors： Sadlier DM,Ouyang X,McMahon B,Mu W,Ohashi R,Rodgers K,Murray D,Nakagawa T,Godson C,Doran P,Brady HR,Johnson RJ

更新日期：2005-12-01 00:00:00

abstract：:11 beta-hydroxysteroid dehydrogenase (11 beta-OHSD) transforms endogenous glucocorticoids to their respective "biologically inert" 11-dehydro derivatives. A decrease in enzyme activity allows glucocorticoids to induce mineralocorticoid-like renal sodium retention. Since positive sodium balance is required for optimum ...

journal_title：Kidney international

authors： Brem AS,Bina B,Matheson KL,Barnes JL,Morris DJ

更新日期：1994-03-01 00:00:00

abstract：:The present studies were undertaken to assess the effects of 5'-N-ethylcarboxamideadenosine (NECA), an adenosine analogue, on erythropoietin (Epo) production. NECA (0.05 and 0.1 mumol/kg i.v.) produced significant increases in serum Epo levels (368.8 +/- 56.1 and 384.6 +/- 45.9 mU/ml, respectively) in exhypoxic polycy...

journal_title：Kidney international

authors： Nakashima J,Ohigashi T,Brookins JW,Beckman BS,Agrawal KC,Fisher JW

更新日期：1993-10-01 00:00:00

abstract：:The hypertrophy of renal proximal tubular cells occurs as an adaptive response to a variety of stimuli and may be involved with the progression of renal disease. Angiotensin II acting alone or in combination with other growth factors has been implicated in this process. The aims of this study were to identify the role...

journal_title：Kidney international

authors： Chatterjee PK,Weerackody RP,Mistry SK,Hawksworth GM,McLay JS

更新日期：1997-09-01 00:00:00

abstract：:In normal subjects, beta-adrenergic stimulation lowers the serum potassium, whereas alpha-stimulation raises it. Epinephrine, a mixed alpha and beta agonist, acutely lowers the blood potassium in normal subjects, but not in patients with end-stage renal disease. This study was designed to determine whether the resista...

journal_title：Kidney international

authors： Allon M,Shanklin N

更新日期：1991-12-01 00:00:00

abstract：:Daily calcitriol therapy has been reported to improve linear growth in children with renal bone disease, and 1,25-dihydroxyvitamin D is a key regultor of chondrocyte proliferation and differentiation. Whereas large intermittent doses of calcitriol can lower serum parathyroid hormone (PTH) levels and reverse the skelet...

journal_title：Kidney international

authors： Kuizon BD,Goodman WG,Jüppner H,Boechat I,Nelson P,Gales B,Salusky IB

更新日期：1998-01-01 00:00:00

abstract：:Pain is a common complaint in patients with autosomal-dominant polycystic kidney disease, and a systematic approach is needed to differentiate the etiology of the pain and define an approach to management. A thorough history is the best clue to the multifactorial causes of the pain, superimposed upon an understanding ...

journal_title：Kidney international

authors： Bajwa ZH,Gupta S,Warfield CA,Steinman TI

更新日期：2001-11-01 00:00:00

abstract：:The cellular redox state is altered in a number of pathological conditions, including various forms of glomerular injury and diabetes. For example, glucose, via the pentose phosphate pathway generates NADPH, which maintains glutathione (GSH) (part of a major intracellular reducing system) in its reduced state. GSH in ...

journal_title：Kidney international

authors： Shan Z,Tan D,Satriano J,Silbiger S,Schlondorff D

更新日期：1994-08-01 00:00:00

abstract：:The OSCAR study was a multicenter, prospective randomized open-label blinded end-point study of 1164 Japanese elderly hypertensive patients comparing the efficacy of angiotensin II receptor blocker (ARB) uptitration to an ARB plus calcium channel blocker (CCB) combination. In this prospective study, we performed presp...

journal_title：Kidney international

authors： Kim-Mitsuyama S,Ogawa H,Matsui K,Jinnouchi T,Jinnouchi H,Arakawa K

更新日期：2013-01-01 00:00:00

abstract：:Australia's Indigenous people have high rates of chronic kidney disease and kidney failure. To define renal disease among these people, we reviewed 643 renal biopsies on Indigenous people across Australia, and compared them with 249 biopsies of non-Indigenous patients. The intent was to reach a consensus on pathologic...

journal_title：Kidney international

authors： Hoy WE,Samuel T,Mott SA,Kincaid-Smith PS,Fogo AB,Dowling JP,Hughson MD,Sinniah R,Pugsley DJ,Kirubakaran MG,Douglas-Denton RN,Bertram JF

更新日期：2012-12-01 00:00:00

abstract：:During vasculitis, activation of the kinin system induces inflammation, whereby the kinin B1-receptor is expressed and activated after ligand binding. Additionally, activated blood cells release microvesicles into the circulation. Here we determined whether leukocyte-derived microvesicles bear B1-kinin receptors durin...

journal_title：Kidney international

authors： Kahn R,Mossberg M,Ståhl AL,Johansson K,Lopatko Lindman I,Heijl C,Segelmark M,Mörgelin M,Leeb-Lundberg LM,Karpman D

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Aldosterone has been known for many years to increase sodium (Na(+)) reabsorption by the distal nephron. The present in vitro experiments investigated the effect of the hormone on calcium (Ca(2+)) transport by the luminal membrane of the rabbit nephron, independent of any systemic influence. METHODS:Proxima...

journal_title：Kidney international

authors： Leclerc M,Brunette MG,Couchourel D

更新日期：2004-07-01 00:00:00

abstract：:Pathogenesis of vascular calcification in chronic kidney disease. Background. Hyperphosphatemia and hypercalcemia are independent risk factors for higher incidence of cardiovascular events in patients with chronic kidney disease. In addition to increased calcium-phosphate product, hyperphosphatemia accelerates the pro...

journal_title：Kidney international

authors： Cozzolino M,Brancaccio D,Gallieni M,Slatopolsky E

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus-associated nephropathy (HIVAN) has become the third leading cause of end-stage renal disease (ESRD) in African Americans, and is expected to grow exponentially. Highly active antiretroviral therapy (HAART) has significantly prolonged the survival of patients with HIV infection. D...

journal_title：Kidney international

authors： Kumar MS,Sierka DR,Damask AM,Fyfe B,McAlack RF,Heifets M,Moritz MJ,Alvarez D,Kumar A

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:We developed an electroporation-mediated gene transfer method targeting glomerular mesangial cells. Injecting DNA solution via renal artery followed by electric pulses using tweezers-type electrodes could result in efficient transfection in mesangial cells. Therefore, this gene transfer system opened a feasi...

journal_title：Kidney international

authors： Isaka Y,Nakamura H,Mizui M,Takabatake Y,Horio M,Kawachi H,Shimizu F,Imai E,Hori M

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:The relationship between blood pressure (BP) and mortality in hemodialysis patients has remained controversial. Some studies suggested that a lower pre- or postdialysis BP was associated with excess mortality, while others showed poorer outcome in patients with uncontrolled hypertension. We conducted a multi...

journal_title：Kidney international

authors： Shoji T,Tsubakihara Y,Fujii M,Imai E

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Increased venous pressure (VP) and decreased access flow (Qa) are predictors of dialysis access graft thrombosis. VP is easily obtainable. Qa assessment requires a special device and takes more time. The aims of our randomized multicenter studies were to compare outcome in patients with grafts monitored by V...

journal_title：Kidney international

authors： Smits JH,van der Linden J,Hagen EC,Modderkolk-Cammeraat EC,Feith GW,Koomans HA,van den Dorpel MA,Blankestijn PJ

更新日期：2001-04-01 00:00:00

abstract：:It is well established that nocturnal hypoxemia in sleep apnea causes an inversion of the circadian arterial pressure rhythm and triggers nocturnal hypertension. Since sleep apnea is very frequent in dialysis patients, we hypothesized that nocturnal hypoxemia may be a factor that contributes to alter the 24-hour arter...

journal_title：Kidney international

authors： Zoccali C,Benedetto FA,Tripepi G,Cambareri F,Panuccio V,Candela V,Mallamaci F,Enia G,Labate C,Tassone F

更新日期：1998-04-01 00:00:00

abstract：:Patients receiving cadaveric kidney transplants often experience delayed graft function. As iodinated contrast media injection (ICMI), necessary for cerebral angiography, which is often used to diagnose brain death, can be nephrotoxic, we compared renal function recovery (RFR) and 1-year and long-term graft survival a...

journal_title：Kidney international

authors： Vigneau C,Fulgencio JP,Godier A,Chalem Y,El Metaoua S,Rondeau E,Tuppin P,Bonnet F

更新日期：2006-09-01 00:00:00

abstract：:Adenosine is known to decrease renal blood flow and glomerular filtration rate. We have tested the hypothesis that adenosine exerts contractile effects on mesangial cells. Furthermore, we have studied, using selective agonists and antagonists for adenosine, which kind of adenosine receptor, A1 or A2, is mainly implica...

journal_title：Kidney international

authors： Olivera A,Lamas S,Rodriguez-Puyol D,López-Novoa JM

更新日期：1989-06-01 00:00:00

abstract：:This study examined the consequences of nephrectomy in United States Army personnel who lost a kidney due to trauma during World War II (WWII). Records of 62 servicemen who underwent nephrectomy at an average age of 25 years were obtained. Mortality was compared with that of WWII servicemen of the same age. Medical re...

journal_title：Kidney international

authors： Narkun-Burgess DM,Nolan CR,Norman JE,Page WF,Miller PL,Meyer TW

更新日期：1993-05-01 00:00:00

abstract：:Experimental studies have demonstrated the cardinal role played by the mononuclear phagocyte system in the removal of antigen-antibody complexes. To assess the functional capacity of phagocytes in patients with renal disease, 33 normal subjects, 10 patients with mesangial proliferative glomerulonephritis, 8 patients w...

journal_title：Kidney international

authors： Ooi YM,Ooi BS

更新日期：1983-06-01 00:00:00

abstract：:The use of the immuno-suppressant cyclosporine A (CsA) after transplantation has been associated with less favorable plasma lipid profiles, which may contribute to the high incidence of cardiovascular morbidity and mortality in transplant recipients. Recent studies have suggested that oxidative modification of LDL pla...

journal_title：Kidney international

authors： van den Dorpel MA,Ghanem H,Rischen-Vos J,Man in't Veld AJ,Jansen H,Weimar W

更新日期：1997-05-01 00:00:00

abstract：:Tubular function studies have shown that nephrectomy leads to a sharp increase in potassium secretion by initial collecting tubules. The aim of this study was to examine the relationship between potassium transport and the cellular morphology of the distal nephron. Clearance and ultrastructural studies were conducted ...

journal_title：Kidney international

authors： Zalups RK,Stanton BA,Wade JB,Giebisch G

更新日期：1985-04-01 00:00:00

abstract：:Podocytes are highly differentiated cells that play an important role in maintaining glomerular filtration barrier integrity; a function regulated by small GTPase proteins of the Rho family. To investigate the role of Rho A in podocyte biology, we created transgenic mice expressing doxycycline-inducible constitutively...

journal_title：Kidney international

authors： Wang L,Ellis MJ,Gomez JA,Eisner W,Fennell W,Howell DN,Ruiz P,Fields TA,Spurney RF

更新日期：2012-06-01 00:00:00

abstract：:In rodents, mercuric chloride (HgCl2) causes an autoimmune disorder with glomerulonephritis (GN), and represents an animal model for the pathogenesis of GN. We have tested the hypothesis that HgCl2 induces major histocompatibility complex (MHC) expression in renal parenchymal cells, and studied the kinetics of this in...

journal_title：Kidney international

authors： Madrenas J,Parfrey NA,Halloran PF

更新日期：1991-02-01 00:00:00

abstract：:Because the comparison of survival in patients with renal failure treated by dialysis and transplantation may be biased by pretreatment prognostic differences in the patients who receive these two therapies, we quantified the pretreatment prognosis of all 430 dialysis and transplant patients who began therapy for end-...

journal_title：Kidney international

authors： Hutchinson TA,Thomas DC,Lemieux JC,Harvey CE

更新日期：1984-07-01 00:00:00

abstract：BACKGROUND:Segmental glomerular necrosis has been described in the biopsy material in a minority of patients with idiopathic IgA nephropathy in the oldest studies on this disease, but this marker of active capillaritis has received little attention in the subsequent literature, and its significance and relevance for th...

journal_title：Kidney international

authors： D'Amico G,Napodano P,Ferrario F,Rastaldi MP,Arrigo G

更新日期：2001-02-01 00:00:00