Practical management of C3 glomerulopathy and Ig-mediated MPGN: facts and uncertainties.

Abstract:

:In recent years, a substantial body of experimental and clinical work has been devoted to C3 glomerulopathy and Ig-mediated membranoproliferative glomerulonephritis. Despite the rapid accumulation of data, several uncertainties about these 2 rare forms of nephropathies persist. They concern their pathophysiology, classification, clinical course, relevance of biomarkers and of pathology findings, and assessment of the efficacy of the available therapies. The present review discusses the impact of these uncertainties on the clinical management of patients.

journal_name

Kidney Int

journal_title

Kidney international

authors

Fakhouri F,Le Quintrec M,Frémeaux-Bacchi V

doi

10.1016/j.kint.2020.05.053

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

1135-1148

issue

5

eissn

0085-2538

issn

1523-1755

pii

S0085-2538(20)30721-3

journal_volume

98

pub_type

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