Cytokines, tryptophan and anorexia in cancer patients before and after surgical tumor ablation.

abstract：AIM:The purpose of this study was to identify patient-, facility-, disease-, and treatment-specific characteristics that increase mortality in patients with upper limb osteosarcoma. PATIENTS AND METHODS:The National Cancer Data Base (NCDB) was queried for bone cancer. With Cox regression, the demographic, facility, tu...

journal_title：Anticancer research

authors： Restrepo DJ,Huayllani MT,Boczar D,Sisti A,Spaulding AC,Carter RE,Moran SL,Parker AS,Perdikis G,Forte AJ

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND/AIM:In addition to its cytocidal effects as a microtubule dynamics inhibitor, eribulin mesylate (eribulin) regulates the tumour microenvironment. We examined the clinical significance of tumour infiltrating lymphocytes (TILs) and transforming growth factor-β (TGF-β), which are local markers of host immunity,...

journal_title：Anticancer research

authors： Kashiwagi S,Asano Y,Goto W,Takada K,Morisaki T,Kouhashi R,Yabumoto A,Tanaka S,Takashima T,Ohsawa M,Hirakawa K,Ohira M

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND/AIM:No standard treatment has been established for poorly-differentiated neuroendocrine carcinomas (PDNEC). The aim of this study is to evaluate the response to the combination of three drugs. MATERIAL AND METHODS:We reviewed 21 PDNEC patients treated from 2008 to 2013 in two Institutions. Five patients wer...

journal_title：Anticancer research

authors： Bajetta E,Catena L,Biondani P,Pusceddu S,Valente M,Bianco N,Novelli E

更新日期：2014-10-01 00:00:00

abstract：:Tricot et al have reported that the nucleoside analog tiazofurin can induce hematologic remissions in patients with chronic myelogenous leukemia in blast crisis (CML-BC). These reports prompted us to begin a derivative, phase II trial of tiazofurin in CML-BC to determine if the promising findings reported by these inv...

journal_title：Anticancer research

authors： Wright DG,Boosalis MS,Waraska K,Oshry LJ,Weintraub LR,Vosburgh E

更新日期：1996-11-01 00:00:00

abstract：AIM:The aim of the present study was to determine if febuxostat could prevent tumor lysis syndrome (TLS) in children who received induction chemotherapy for hematologic malignancies. PATIENTS AND METHODS:A retrospective analysis was performed in 45 pediatric patients with hematological malignancies who received febuxo...

journal_title：Anticancer research

authors： Kishimoto K,Kobayashi R,Hori D,Sano H,Suzuki D,Kobayashi K

更新日期：2017-10-01 00:00:00

abstract：:Basal cell carcinoma (BCC) is a locally invasive neoplasm, rarely metastatic, yet capable of significant local destruction and disfigurement. Invasion into the bone is uncommon and only a few cases of invasion into facial bones, but never to the mandible or maxilla, have been described. We report three patients with B...

journal_title：Anticancer research

authors： Nagler RM,Laufer D

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIM:Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a novel clinical approach to the treatment of peritoneal carcinomatosis. A well-established, not anatomic ex vivo PIPAC model was used to investigate the influence of changes in internal pressure, distance of the Micropump(©) (MIP) to the distri...

journal_title：Anticancer research

authors： Khosrawipour V,Khosrawipour T,Falkenstein TA,Diaz-Carballo D,Förster E,Osma A,Adamietz IA,Zieren J,Fakhrian K

更新日期：2016-09-01 00:00:00

abstract：:Homogeneous subpopulations, which are endowed with low or high metastatic potential, were selected from Lewis lung carcinoma (3LL) in an attempt to correlate metastatic phenotype with specific properties of tumor cells. Since the growth of malignant cells at secondary sites could depend on their ability to respond to ...

journal_title：Anticancer research

authors： Perrotti D,Cimino L,Falcioni R,Tibursi G,Gentileschi MP,Sacchi A

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:The risk of chronic obstructive pulmonary disease (COPD) is related to Gc protein allele type, such as Gc*1F, Gc*IS, Gc*2. It has been reported that Gc*1F increased COPD risk, while Gc*2 suppressed the risk. Thus, the allele type of Gc protein is an important factor in COPD. These Gc proteins differ in sugar...

journal_title：Anticancer research

authors： Ohkura K,Nagasawa H,Uto Y,Okamura N,Murakami A,Hori H

更新日期：2006-11-01 00:00:00

abstract：:We examined the antitumor effect of lipopolysaccharide extracted from Pantoea agglomerans, a Gram-negative bacterium, using intradermal administration on murine syngeneic tumors, Meth A fibrosarcoma, MH134 hepatoma and Lewis lung (LL) carcinoma. The latter two tumors are known to be relatively low in immunogenicity, h...

journal_title：Anticancer research

authors： Inagawa H,Nishizawa T,Noguchi K,Minamimura M,Takagi K,Goto S,Soma G,Mizuno D

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND/AIM:Glioblastoma multiforme (GBM) is a malignant primary brain tumor with high rates of recurrence. This study aimed to investigate the effect of repurposed drug combinations on GBM. MATERIALS AND METHODS:Viability of U87 MG and 11ST patient-derived GMB cell lines, after valproic acid, tranylcypromine or ri...

journal_title：Anticancer research

authors： Sachkova A,Sperling S,Mielke D,Schatlo B,Rohde V,Ninkovic M

更新日期：2019-01-01 00:00:00

abstract：:We assessed the prognostic value of the local tumor characteristics inflammatory stromal reaction (ISR) and vascular space invasion (VSI) together with established prognostic criteria, in cervical cancer patients. One hundred and forty-two patients with carcinoma of the cervix stage IB to IIB undergoing radical hyster...

journal_title：Anticancer research

authors： Kainz C,Gitsch G,Tempfer C,Heinzl H,Koelbl H,Breitecker G,Reinthaller A

更新日期：1994-09-01 00:00:00

abstract：:L1210 cell lines selected for resistance to deoxyadenosine exhibit altered steady-state levels of the mRNA for the early response genes and p53. In the deoxyadenosine-resistant cell lines (Y8 and ED2), the levels of the mRNAs for p53 and c-jun were markedly decreased while the steady-state levels for mRNAs for c-myc, ...

journal_title：Anticancer research

authors： Cory JG,He AW,Cory AH

更新日期：1996-11-01 00:00:00

abstract：:The triterpenoid fraction (100 and 200 mg/kg) of the fruit bodies of Ganoderma lucidum inhibited primary solid-tumor growth in the spleen, liver metastasis and secondary metastatic tumor growth in the liver in intrasplenic Lewis lung carcinoma (LLC)-implanted mice. In addition, the triterpenoid fraction (800 microgram...

journal_title：Anticancer research

authors： Kimura Y,Taniguchi M,Baba K

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND/AIM:Due to their unique composition of health-promoting compounds, the consumption of hazelnuts may contribute to the prevention of colon cancer. MATERIALS AND METHODS:Since hazelnuts are often consumed roasted, the impact of different roasting conditions (RC1=140.6°C/25 min, RC2=155.1°C/20 min and RC3=180....

journal_title：Anticancer research

authors： Glei M,Fischer S,Lamberty J,Ludwig D,Lorkowski S,Schlörmann W

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The mitochondrial protein translocase of inner mitochondrial membrane 17 homolog A (TIMM17A) has been identified as a biomarker of breast cancer. The present study aimed to investigate the biological role of TIMM17A in human breast cancer cells. MATERIALS AND METHODS:Anti-TIMM17A transgenes were stably tran...

journal_title：Anticancer research

authors： Yang X,Si Y,Tao T,Martin TA,Cheng S,Yu H,Li J,He J,Jiang WG

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Cardiac tamponade, due to bleeding in the pericardial space after esophagectomy for esophageal cancer, is an extremely rare complication and may be associated with sudden hemodynamic instability that can lead to death unless there is prompt diagnosis and appropriate treatment. CASE REPORT:A 76-year-old man ...

journal_title：Anticancer research

authors： Ito S,Morita M,Nanbara S,Nakaji Y,Ando K,Hiyoshi Y,Okamoto T,Saeki H,Oki E,Kawanaka H,Tanoue Y,Maehara Y

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIM:To predict pCR during neoadjuvant chemotherapy is still difficult. The aim of this study was to evaluate the optimal tumor reduction rate and modalities for predicting pCR after two cycles of docetaxel. PATIENTS AND METHODS:We analyzed 52 patients with HER2-positive or triple-negative breast cancer. The...

journal_title：Anticancer research

authors： Kuba S,Maeda S,Matsumoto M,Yamanouchi K,Iwata T,Morita M,Sakimura C,Otsubo R,Yano H,Sato S,Kanetaka K,Nagayasu T,Eguchi S

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The heterogeneity in prostate cancer is the reason for the difficult diagnosis and prognosis of this tumor. In this study, we looked for a correlation between prostate specific antigen (PSA), tumor staging and DNA cytophotometry. MATERIALS AND METHODS:Twenty-two prostates (pT1-T4) from patients with prostat...

journal_title：Anticancer research

authors： Krause FS,Feil G,Bichler KH,Schrott KM,Akcetin ZY,Engehausen DG

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND/AIM:Interleukin-32 (IL32) has been newly-identified as a proinflammatory cytokine. In the present study, we aimed to clarify the clinical role of IL32-positive cells in esophageal squamous cell cancer (ESCC) and regulatory T-cell (Treg) infiltration in the stroma. A total of 179 patients with ESCC who underw...

journal_title：Anticancer research

authors： Nabeki B,Ishigami S,Uchikado Y,Sasaki K,Kita Y,Okumura H,Arigami T,Kijima Y,Kurahara H,Maemura K,Natsugoe S

更新日期：2015-05-01 00:00:00

abstract：:As with SV40-transformed BHK cells (1), pretreatment of BHK cells with 1-beta-D-arabinofuranosylcytosine (araC) very markedly enhanced the resistance frequency to N-phosphonoacetyl-L-aspartate (PALA) but only modestly increased the resistance frequency to vincristine (VCR). AraC pretreatment of cells that already had ...

journal_title：Anticancer research

authors： Chen Y,Goz B,Kirkman L

更新日期：1993-01-01 00:00:00

abstract：:Many arylamines (including carcinogens) and hydrazine drugs are acetylated by the cytosolic N-acetyltransferase (NAT). NAT plays an important role in the first step of arylamine metabolism and has been found in immortalized human cell lines, human and laboratory animal tissues. Human colon tumor cell line (colo 205) h...

journal_title：Anticancer research

authors： Lin WC,Shun C,Huang LJ,Kuo SC,Yu CS,Chung JG

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Since superparamagnetic iron oxide nanoparticles (SPION) possess unique features, they provide a huge platform for medical applications, especially for cancer diagnosis and therapy (e.g. imaging, and drug targeting). However, heterogeneous effects on mammalian cells with regard to reproductive tissue are des...

journal_title：Anticancer research

authors： Pöttler M,Hofmann S,Dürr S,Unterweger H,Wiest I,Zaloga J,Alexiou C,Jeschke U,Janko C

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:The effectiveness and improvement in quality of life (QOL) of a long-acting formulation of octreotide (LAR) administration for cancer patients, with chronic loperamide-refractory diarrhea not attributed to medical therapy, were investigated. PATIENTS AND METHODS:Twenty-nine patients with chronic loperamide-r...

journal_title：Anticancer research

authors： Mystakidou K,Katsouda E,Tsilika E,Smyrniotis V,Vassiliou I,Tsiatas M,Vlahos L

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The balance between cell proliferation and apoptosis plays a significant role in cancer development. The expressions of the p53 and c-myc genes, both strongly related to cell proliferation and apoptosis, were studied in sequential histological grades of oral carcinogenesis in an animal model. MATERIALS AND ...

journal_title：Anticancer research

authors： Papakosta V,Vairaktaris E,Vylliotis A,Derka S,Nkenke E,Vassiliou S,Lazaris A,Mourouzis C,Rallis G,Spyridonidou S,Anagnostopoulou S,Perrea D,Donta I,Yapijakis C,Patsouris E

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND/AIM:Silencing mediator of retinoid and thyroid receptors (SMRT) is a nuclear corepressor in thyroid and estrogen hormones pathways. The aim was to evaluate SMRT expression in relation to thyroid hormone levels and prognostic markers in breast cancer (BC). PATIENTS AND METHODS:Serum and tumor tissues were ob...

journal_title：Anticancer research

authors： Nisman B,Allweis TM,Carmon E,Kadouri L,Maly B,Maimon O,Meierovich A,Peretz T

更新日期：2020-11-01 00:00:00

abstract：:The authors report their experience in the radioimmunodetection of recurrent colorectal cancer in comparison with traditional examinations. 485 patients were studied after radical surgery for colorectal cancer: 168 (Group 1) were studied with a radioimmunoassisted follow-up plan including: Immunoscintigraphy (IS), ser...

journal_title：Anticancer research

authors： Prati U,Roveda L,Cantoni A,Saponaro R,Bosi F,Sandolo R,Zonta A

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND/AIM:Trifluridine (FTD) is a key component of the novel oral antitumor drug trifluridine/tipiracil that has been approved for the treatment of metastatic colorectal cancer. In this study, a comprehensive analysis of DNA replication profile in FTD-treated colon cancer cells was performed. MATERIALS AND METHOD...

journal_title：Anticancer research

authors： Kobunai T,Matsuoka K,Takechi T

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND/AIM:Cancer incidence and mortalities are growing worldwide, therefore research and development of more effective and less invasive treatments, such as photodynamic therapy, are needed. Herein, we investigated the methylene blue (MB) photoactivation effects in lung epithelial cells (BEAS-2B) and lung adenocar...

journal_title：Anticancer research

authors： Rodríguez-Córdova RJ,Gutiérrez-Valenzuela CA,Bojang P,Esquivel R,Hernández P,Ramos KS,Guzmán-Zamudio R,Lucero-Acuña A

更新日期：2019-07-01 00:00:00

abstract：:Induction of apoptosis is an approach to suppress carcinogenesis. The effects of a 12-week treatment of female Sprague-Dawley rats with indole-3-carbinol (I3C), beta-naphthoflavone or vehicle (40% ethanol in corn oil), by oral gavages starting 3 weeks after initiation of mammary tumorigenesis with 7,12-dimethylbenz[al...

journal_title：Anticancer research

authors： Zhang X,Malejka-Giganti D

更新日期：2003-05-01 00:00:00