Prevention and treatment of urinary catheter-related infections in older patients.

abstract：BACKGROUND:Osteoporosis is a common cause of disability and death in elderly men and women. Until 2007, Australian Government-subsidized use of oral bisphosphonates, raloxifene and calcitriol (1alpha,25-dihydroxycholecalciferol) was limited to secondary prevention (requiring x-ray evidence of previous low-trauma fractu...

journal_title：Drugs & aging

authors： Hollingworth SA,Gunanti I,Nissen LM,Duncan EL

更新日期：2010-03-01 00:00:00

abstract：:The number of older patients is increasing globally. Combined with the growing number of ambulatory surgeries, many older patients will undergo ambulatory surgery in the future. The ambulatory setting offers many advantages: early mobilization, higher patient satisfaction, lower costs, and a low incidence of several c...

journal_title：Drugs & aging

authors： Hansen J,Rasmussen LS,Steinmetz J

更新日期：2020-12-01 00:00:00

abstract：:Falls are a common health problem for older people, and psychotropic medications have been identified as an important independent fall risk factor. The objective of this paper was to review the literature relating to the effect of psychotropic medications on falls in older people, with a particular focus on evidence s...

journal_title：Drugs & aging

authors： Hill KD,Wee R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Pharmacotherapy with statins (HMG-CoA reductase inhibitors) is the cornerstone for lipid management in individuals with or at risk of developing cardiovascular diseases. Although the clinical benefits of statins are established for both women and men, there is evidence of a gender difference in their use. Th...

journal_title：Drugs & aging

authors： Bhattacharjee S,Findley PA,Sambamoorthi U

更新日期：2012-12-01 00:00:00

abstract：:Elderly rheumatoid arthritis (RA) is classified into two clinical subsets, elderly-onset RA (EORA) and younger-onset elderly RA. With the improvement of life expectancy in the general population and advent of the super-aging society, the number of patients with EORA is anticipated to increase. Both large and small joi...

journal_title：Drugs & aging

authors： Sugihara T,Harigai M

更新日期：2016-02-01 00:00:00

abstract：:An increasing number of elderly patients are exposed to cardiovascular drugs for the treatment of acute and/or chronic conditions. This is a result of the progressive aging of the population, a common feature in most industrialised countries, and an improvement in primary and secondary cardiovascular prevention strate...

journal_title：Drugs & aging

authors： Mangoni AA

更新日期：2005-01-01 00:00:00

abstract：:Generalised pruritus is common in the elderly. Idiopathic 'senile pruritus' is a diagnosis of exclusion, and an underlying systemic disorder should be sought. Thyroid disease, haematological malignancy, iron deficiency, cholestasis or renal impairment may be responsible for pruritus. Rarely pruritus may occur after ce...

journal_title：Drugs & aging

authors： Lonsdale-Eccles A,Carmichael AJ

更新日期：2003-01-01 00:00:00

abstract：:NSAIDs are a widely used class of analgesic and anti-inflammatory drugs that act by inhibiting the cyclo-oxygenase (COX) enzyme. However, because of their nonspecificity of action, use of these agents as long-term therapy for chronic pain in diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA) is often d...

journal_title：Drugs & aging

authors： Bansal SS,Joshi A,Bansal AK

更新日期：2007-01-01 00:00:00

abstract：:Despite the availability of angiotensin converting enzyme (ACE) inhibitors for patients with congestive heart failure (CHF), mortality and morbidity remains unacceptably high. CHF is thought to progress as a result of activation of endogenous neurohormonal systems which are activated by the initial myocardial injury. ...

journal_title：Drugs & aging

authors： Tsuyuki RT,McAlister FA,Teo KK

更新日期：2000-01-01 00:00:00

abstract：:The consumption of medications with anticholinergic activity has been suggested to result in the adverse effects of mental confusion, visual disturbance, and muscle weakness, which may lead to falls. Existing published evidence linking anticholinergic drugs with falls, however, remains weak. This study was conducted t...

journal_title：Drugs & aging

authors： Tan MP,Tan GJ,Mat S,Luben RN,Wareham NJ,Khaw KT,Myint PK

更新日期：2020-02-01 00:00:00

abstract：:Management of hypertension in the elderly should take into account, in particular, the possible negative impact of antihypertensive drugs on the patient's quality of life, the deterioration of which may result in a loss of independence and reduced treatment compliance. Quality of life is recognised as a multifactorial...

journal_title：Drugs & aging

authors： Fogari R,Zoppi A

更新日期：2004-01-01 00:00:00

abstract：:Streptococcus pneumoniae has been recognised as a major cause of pneumonia since the time of Sir William Osler. Drug-resistant S. pneumoniae (DRSP), which have gradually become resistant to penicillins as well as more recently developed macrolides and fluoroquinolones, have emerged as a consequence of indiscriminate u...

journal_title：Drugs & aging

authors： Neralla S,Meyer KC

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To assess, by smoothness index (SI), distribution of the antihypertensive effect of extended-release (ER) felodipine over 24 hours in elderly patients with hypertension. METHODS:After a 4-week washout phase, 35 elderly patients (mean age 69 +/- 4 years) with mild-to-moderate hypertension received 2 weeks' tr...

journal_title：Drugs & aging

authors： Antonicelli R,Omboni S,Giovanni DC,Ansuini R,Mori A,Gesuita R,Parati G,Paciaroni E

更新日期：2002-01-01 00:00:00

abstract：:The focus of this review is hormone replacement therapy (HRT) with continuous oral 17 beta-estradiol (herein referred to as estradiol) 2 mg/day plus sequential oral dydrogesterone 10 or 20 mg/day for 14 days of each 28-day cycle. According to data from nonblind trials, this regimen relieves climacteric symptoms, prese...

journal_title：Drugs & aging

authors： Foster RH,Balfour JA

更新日期：1997-10-01 00:00:00

abstract：:Osteoarthritis (OA) is a major cause of pain and physical disability in adults, and an increasingly common disease given its associations with aging and a growing obese/overweight population. Paracetamol is widely recommended for analgesia at an early stage in the management of OA, and, although frequently prescribed,...

journal_title：Drugs & aging

authors： Conaghan PG,Arden N,Avouac B,Migliore A,Rizzoli R

更新日期：2019-04-01 00:00:00

abstract：:New treatments and treatment protocols for diseases affecting the elderly are evolving as we strive to meet the needs of an aging society. To help you keep up to date with the latest advances worldwide on all aspects of drug therapy and patient management, this section of the journal brings you information selected fr...

journal_title：Drugs & aging

authors：

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Previous studies have investigated the prevalence of drug-drug interactions (DDIs) among the elderly in different care settings, but data describing the frequency and management of DDIs among acute geriatric patients appear to be absent. OBJECTIVE:The aim of this study was to investigate the severity and in...

journal_title：Drugs & aging

authors： Lea M,Rognan SE,Koristovic R,Wyller TB,Molden E

更新日期：2013-09-01 00:00:00

abstract：:Type 2 diabetes mellitus is a complex heterogenous metabolic disorder in which peripheral insulin resistance and impaired insulin release are the main pathogenetic factors. The rapid response of the pancreatic beta-cells to glucose is already markedly disturbed in the early stages of type 2 diabetes mellitus. The cons...

journal_title：Drugs & aging

authors： Landgraf R

更新日期：2000-11-01 00:00:00

abstract：:Giant cell arteritis (GCA) is an inflammatory vasculopathy that involves large- and medium-sized arteries and can cause vision loss, stroke and aneurysms. GCA occurs in people aged >50 years and is more common in women. A higher incidence of the disease is observed in populations from Northern European countries. Poly...

journal_title：Drugs & aging

authors： Schmidt J,Warrington KJ

更新日期：2011-08-01 00:00:00

abstract：:Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) usually affect adults and older populations. The well recognized clinical (i.e., granulomatosis with polyangiitis [GPA], microscopic polyangiitis, and eosinophilic GPA) and serological phenotypes (i.e., anti-MPO-ANCA, anti-PR3-ANCA and ANCA nega...

journal_title：Drugs & aging

authors： Berti A,Caporali R,Montecucco C,Paolazzi G,Monti S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:For physicians dealing with patients with a limited life expectancy, knowing the time to benefit (TTB) of preventive medication is essential to support treatment decisions. OBJECTIVE:The aim of this study was to investigate the usefulness of statistical process control (SPC) for determining the TTB in relat...

journal_title：Drugs & aging

authors： van de Glind EM,Willems HC,Eslami S,Abu-Hanna A,Lems WF,Hooft L,de Rooij SE,Black DM,van Munster BC

更新日期：2016-05-01 00:00:00

abstract：:Pharmacological treatment of depression in old age is associated with an increased risk of adverse pharmacokinetic and pharmacodynamic drug interactions. Elderly patients may have multiple disease states and, therefore, may require a variety of other drugs. In addition to polypharmacy, other factors such as age-relate...

journal_title：Drugs & aging

authors： Spina E,Scordo MG

更新日期：2002-01-01 00:00:00

abstract：:Asthma is a common airway disease found in people of all ages, although most studies of asthma therapies are focused on adolescent and young adults. Little information exists on the use of asthma therapeutics in the older patient (>65 years of age). The newest therapeutic class to be released in the US for the treatme...

journal_title：Drugs & aging

authors： Grayson MH,Korenblat PE

更新日期：2006-01-01 00:00:00

abstract：:In contrast with the earlier stages and, in particular, the predementia stage, of Alzheimer's disease (AD), severe dementia is often neglected. However, the advanced stages of dementia are just as important as the earlier stages because of their frequency, their impact on the lives of patients and their caregivers, an...

journal_title：Drugs & aging

authors： Voisin T,Vellas B

更新日期：2009-01-01 00:00:00

abstract：:We conducted a review of drugs that were most commonly associated with inducing seizures in the elderly population. The method for determining the risk of these agents includes evaluating the utilisation and the percentage of adverse events in previous studies and case reports. Classes of medications, such as anti-psy...

journal_title：Drugs & aging

authors： Franson KL,Hay DP,Neppe V,Dahdal WY,Mirza WU,Grossberg GT,Chatel DM,Szwabo PA,Kotegal S

更新日期：1995-07-01 00:00:00

abstract：:Faecal incontinence occurs in up to 10% of community dwelling persons > or = 65 years of age and approximately 50% of nursing home residents. It is a vastly under-reported problem that has a devastating effect on those who experience it as well as their spouses and caregivers. There are three broad categories of faeca...

journal_title：Drugs & aging

authors： Wald A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Multiple drug use is common among old, frail nursing home residents who are, as a consequence, susceptible to adverse effects and drug interactions. This study uses the updated Beers criteria for potentially inappropriate drug (PID) use in older adults to determine the extent and nature of PIDs...

journal_title：Drugs & aging

authors： Hosia-Randell HM,Muurinen SM,Pitkälä KH

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:In response to concerns about, and issues pertaining to, medication use practices in residential aged-care facilities (RACFs), the Australian Pharmaceutical Advisory Council (APAC) established a working party on quality use of medicines (QUM) in nursing homes and hostels. The APAC is a representative ministe...

journal_title：Drugs & aging

authors： Cheek J,Gilbert A,Ballantyne A,Penhall R

更新日期：2004-01-01 00:00:00

abstract：:Cardiovascular disease has been inseparable from aging in developed societies and, as a result, it is the commonest cause of mortality in elderly populations. Atherosclerosis is associated with the progressive vascular accumulation of cholesterol-laden lipoproteins, and is linearly associated with the plasma level of ...

journal_title：Drugs & aging

authors： Playford DA,Watts GF

更新日期：1997-06-01 00:00:00

abstract：:The median age for breast cancer diagnosis is 62 years, but a disproportionate number of patients are over the age of 75 years and the majority of those have hormone receptor-positive, human epidermal growth factor receptor-2 (HER2)-negative cancers. This review provides a logical algorithm to guide providers through ...

journal_title：Drugs & aging

authors： Sammons S,Sedrak MS,Kimmick GG

更新日期：2020-05-01 00:00:00