Use of Medications with Anticholinergic Properties and the Long-Term Risk of Hospitalization for Falls and Fractures in the EPIC-Norfolk Longitudinal Cohort Study.

abstract：:New treatments and treatment protocols for diseases affecting the elderly are evolving as we strive to meet the needs of an aging society. To help you keep up to date with the latest advances worldwide on all aspects of drug therapy and patient management, this section of the journal brings you information selected fr...

journal_title：Drugs & aging

authors：

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Limited data are available on the prevalence of inappropriate prescribing of renally cleared drugs in elderly patients in Australia. OBJECTIVES:To quantify and compare the extent of inappropriate prescribing (defined as at least one drug prescribed in an excessive dose or when contraindicated with respect t...

journal_title：Drugs & aging

authors： Khanal A,Peterson GM,Castelino RL,Jose MD

更新日期：2015-05-01 00:00:00

abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting 1 to 3% of individuals over the age of 65 years. While effective therapy exists for treating the bradykinesia, rigidity and tremor associated with the disease, the cause is unknown. There is no treatment available to prevent or slo...

journal_title：Drugs & aging

authors： Ross GW,Petrovitch H

更新日期：2001-01-01 00:00:00

abstract：:The prevalence of intermittent claudication (IC) increases with age; when questioned, older patients consider increased difficulty in walking to be a normal consequence of aging. Although the prognosis for the involved limb with IC is relatively good, IC is an important clinical predictor of increased cardiovascular m...

journal_title：Drugs & aging

authors： Boccalon H

更新日期：1999-04-01 00:00:00

abstract：:Sleep problems are an under-emphasised cause of disability in Parkinson's disease (PD) and may be seen independently of PD, associated with primary PD pathology, or as a result of antiparkinsonian medications. Common sleep disorders include excessive daytime sleepiness, rapid eye movement (REM) sleep behaviour disorde...

journal_title：Drugs & aging

authors： Stacy M

更新日期：2002-01-01 00:00:00

abstract：:Overactive bladder (OAB) is a common constellation of lower urinary tract storage symptoms that causes a significant impact on a person's quality of life. The elderly may be disproportionally impacted by these symptoms due to concomitant poor mobility, comorbid conditions such as diabetes and heart failure, and polyph...

journal_title：Drugs & aging

authors： McFerren SC,Gomelsky A

更新日期：2015-10-01 00:00:00

abstract：:Streptococcus pneumoniae has been recognised as a major cause of pneumonia since the time of Sir William Osler. Drug-resistant S. pneumoniae (DRSP), which have gradually become resistant to penicillins as well as more recently developed macrolides and fluoroquinolones, have emerged as a consequence of indiscriminate u...

journal_title：Drugs & aging

authors： Neralla S,Meyer KC

更新日期：2004-01-01 00:00:00

abstract：:Foot and ankle osteoarthritis (OA) is a common and disabling problem that adversely affects physical function and significantly reduces quality of life. Although the knee was considered to be the lower-limb site most often affected by OA, recent population data showed foot OA is as prevalent as knee OA, and rates incr...

journal_title：Drugs & aging

authors： Paterson KL,Gates L

更新日期：2019-03-01 00:00:00

abstract：:Alzheimer's disease is a chronic progressive disease affecting higher intellectual functioning. The clinical diagnosis is made when the onset of illness is insidious, the course slowly progressive and all the treatable causes of dementia have been ruled out. The use of more stringent criteria has improved clinical dia...

journal_title：Drugs & aging

authors： Hermann C,Stern RG,Losonzcy MF,Jaff S,Davidson M

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Although compelling evidence exists supporting statins (HMG-CoA reductase inhibitors) for secondary prevention in older patients with clinical atherosclerotic diseases, the same cannot be said for primary prevention. OBJECTIVES:The objectives of this study were to estimate the frequency of potential statin ...

journal_title：Drugs & aging

authors： Borne E,Meyer N,Rybarczyck-Vigouret MC,Blanchard O,Lombard M,Lang PO,Vogel T,Michel B

更新日期：2019-10-01 00:00:00

abstract：:Falls are a common health problem for older people, and psychotropic medications have been identified as an important independent fall risk factor. The objective of this paper was to review the literature relating to the effect of psychotropic medications on falls in older people, with a particular focus on evidence s...

journal_title：Drugs & aging

authors： Hill KD,Wee R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Adverse drug reactions are a major cause of hospital admissions in older individuals, with the majority potentially preventable. Despite the apparent magnitude of this problem, little is known about rates of repeat admission to hospital as a result of adverse drug reactions. OBJECTIVES:The objectives of thi...

journal_title：Drugs & aging

authors： Parameswaran Nair N,Chalmers L,Bereznicki BJ,Curtain CM,Bereznicki LR

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Osteoporosis is a common cause of disability and death in elderly men and women. Until 2007, Australian Government-subsidized use of oral bisphosphonates, raloxifene and calcitriol (1alpha,25-dihydroxycholecalciferol) was limited to secondary prevention (requiring x-ray evidence of previous low-trauma fractu...

journal_title：Drugs & aging

authors： Hollingworth SA,Gunanti I,Nissen LM,Duncan EL

更新日期：2010-03-01 00:00:00

abstract：:Elderly people with renal impairment are at high risk for venous thromboembolism (VTE) and acute coronary syndromes (ACS); however, they are also at increased risk for bleeding complications. Evidence-based data for the management of anticoagulation in elderly patients with severe renal impairment, in particular, are ...

journal_title：Drugs & aging

authors： Samama MM

更新日期：2011-03-01 00:00:00

abstract：:The incidence of prostate carcinoma in the US now appears to be declining slightly, as a consequence of removal of prevalent cases from the population by screening. Screening for serum prostate-specific antigen (PSA) levels has been improved by the use of PSA transformations including PSA density, PSA velocity and age...

journal_title：Drugs & aging

authors： Small EJ

更新日期：1998-07-01 00:00:00

abstract：:An increasing number of elderly patients are exposed to cardiovascular drugs for the treatment of acute and/or chronic conditions. This is a result of the progressive aging of the population, a common feature in most industrialised countries, and an improvement in primary and secondary cardiovascular prevention strate...

journal_title：Drugs & aging

authors： Mangoni AA

更新日期：2005-01-01 00:00:00

abstract：:The Medicare programme already funds a large proportion of the medical care for older Americans. However, geriatricians are an underutilized resource for improving the quality of care delivered with Medicare funding, particularly to the most complex patients. Recent legislative changes will increase the involvement of...

journal_title：Drugs & aging

authors： Nusbaum NJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The use of proton pump inhibitors (PPIs) in older adults is high, often inappropriate, and may cause harm. Deprescribing is defined as the reduction, withdrawal, or discontinuation of inappropriate medication. OBJECTIVE:We conducted a systematic review to determine the effectiveness of interventions to depr...

journal_title：Drugs & aging

authors： Wilsdon TD,Hendrix I,Thynne TR,Mangoni AA

更新日期：2017-04-01 00:00:00

abstract：:Cataract surgery is the most frequent surgical procedure requiring anaesthesia in developed countries. It is performed mainly in elderly patients, who present with many coexisting diseases that induce subsequent hazards from general anaesthesia. Cataract anaesthesia is performed following various techniques of regiona...

journal_title：Drugs & aging

authors： Nouvellon E,Cuvillon P,Ripart J,Viel EJ

更新日期：2010-01-01 00:00:00

abstract：:Attempts to control pneumococcal infection by vaccination, undertaken initially in 1911, have gone through 3 phases during the subsequent 8 decades. Initially, vaccines of killed pneumococcal cells prepared in a variety of ways were used in epidemic settings with inconclusive results, although administered to approxim...

journal_title：Drugs & aging

authors： Austrian R

更新日期：1999-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is an acquired inflammatory demyelinating disease of the CNS that is typically diagnosed in the second or third decade of life. It is generally believed that over the last few decades the life expectancy of patients with adult onset MS (AOMS) has approached that of the general population as a r...

journal_title：Drugs & aging

authors： Awad A,Stüve O

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Overactive bladder syndrome (OAB) is associated with various co-morbidities; treatment of these frequently results in multiple medication use (MMU) and the potential for drug-drug interactions, which may lead to adverse events and altered efficacy. With the aging population, the prevalence of MMU is likely t...

journal_title：Drugs & aging

authors： Sand PK,Rovner ES,Watanabe JH,Oefelein MG

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:In the presence of multimorbidity and limited life expectancy (LLE), the need for continued use of preventive medicines becomes uncertain as they may neither improve health nor confer continued health benefits. OBJECTIVE:Our objective was to systematically review the literature to examine the discontinuatio...

journal_title：Drugs & aging

authors： Narayan SW,Nishtala PS

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Age-related changes in the concentration-effect relationship of (+)-O-desmethyl-tramadol [(+)-ODM], tramadol's active metabolite, are not documented in the elderly. OBJECTIVE:The objective of this study was to characterize, in elderly and young subjects, the (+)-ODM pharmacokinetic and pharmacodynamic relat...

journal_title：Drugs & aging

authors： Robertson SS,Mouksassi MS,Varin F

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Over three-quarters of the older population take medications that can potentially cause dry mouth. Physicians or pharmacists rarely inform patients about this adverse effect and its potentially severe damage to the teeth, mouth and general health. OBJECTIVES:The objectives of this study were to (1) identify...

journal_title：Drugs & aging

authors： Nguyen CT,MacEntee MI,Mintzes B,Perry TL

更新日期：2014-01-01 00:00:00

abstract：:Age is a major source of variation in drug response. Social, medical and physiological heterogeneity intertwines to complicate geriatric pharmacotherapy. Inappropriate and excessive use of medication may be the most significant treatable health problem in the elderly. Older people are especially sensitive to antipsych...

journal_title：Drugs & aging

authors： Pollock BG,Mulsant BH

更新日期：1995-04-01 00:00:00

abstract：:The alcohol withdrawal syndrome is common in elderly individuals who are alcohol dependent and who decrease or stop their alcohol intake. While there have been few clinical studies to directly support or refute the hypothesis that withdrawal symptom severity, delirium and seizures increase with advancing age, several ...

journal_title：Drugs & aging

authors： Kraemer KL,Conigliaro J,Saitz R

更新日期：1999-06-01 00:00:00

abstract：:New treatments and treatment protocols for diseases affecting the elderly are evolving as we strive to meet the needs of an aging society. To help you keep up to date with the latest advances worldwide on all aspects of drug therapy and patient management, this section of the journal brings you information selected fr...

journal_title：Drugs & aging

authors：

更新日期：2006-01-01 00:00:00

abstract：:This paper reviews the burden and economic consequences of glaucoma upon healthcare systems and patients, especially elderly patients. An extensive review of the literature was conducted, primarily using MEDLINE, but also by examining selected article reference lists, relevant websites and the proceedings of specialis...

journal_title：Drugs & aging

authors： Rouland JF,Berdeaux G,Lafuma A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Inappropriate prescribing is an important and possibly preventable risk factor for adverse drug reactions (ADRs) in the elderly, and hospital-based studies have shown that a large proportion of admissions is a result of ADRs. However, little is known about how inappropriate drug use (IDU) affec...

journal_title：Drugs & aging

authors： Klarin I,Wimo A,Fastbom J

更新日期：2005-01-01 00:00:00