Abstract：
OBJECTIVE:To study the effect of meal composition on pancreatic polypeptide release during modified sham feeding. DESIGN:In random order and on separate occasions, isocaloric, isothermic, isoosmotic, homogenized meals (1050 kJ; 250 kcal) either rich in fat (walnuts; 64 g fat, 7 g protein, 15 g starch per 100 g), protein (codfish, 1 g fat, 23 g protein per 100 g) or carbohydrates (bananas; 22 g starch, 1 g protein per 100 g) were sham-fed for 30 min by tasting and spitting out the meal. The plasma pancreatic polypeptide response was monitored by radioimmunoassay at 10 min intervals from 20 min before to 120 min after modified sham feeding. SETTING:Department of Gastroenterology and Hepatology of a University Hospital. SUBJECTS:Seven healthy volunteers: 3 male, 4 female; age 45 (range 30-77) years. RESULTS:Integrated plasma pancreatic polypeptide responses to modified sham feeding of codfish (1088 +/- 395 pM*120 min; P < 0.05) and walnuts (1200 +/- 542 pM*120 min) were distinctly higher (P < 0.05) than to modified sham feeding of bananas (-390 +/- 291 pM*120 min). CONCLUSIONS:These results demonstrate that the pancreatic polypeptide response to modified sham feeding is dependent on the composition of the meal.
journal_name
Eur J Clin Nutrjournal_title
European journal of clinical nutritionauthors
Witteman BJ,Edwards-Teunissen K,Hopman WP,Jebbink MC,Masclee AA,Lamers CB,Jansen JBsubject
Has Abstractpub_date
1994-08-01 00:00:00pages
556-60issue
8eissn
0954-3007issn
1476-5640journal_volume
48pub_type
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