Abstract：
:Remarkable diversity of size and health of offspring exists after normal pregnancies. When pregnancies are complicated by an extrinsic variable such as inappropriate maternal nutrition, birth weight and health of the neonate are substantially affected. The placenta is the organ through which respiratory gases, nutrients, and wastes are exchanged between the maternal and fetal systems. Thus, transplacental exchange provides for all the metabolic demands of fetal growth. Transplacental exchange is dependent upon uterine and umbilical blood flow, and blood flow rates are in turn dependent in large part upon vascularization of the placenta. Therefore, factors that influence placental vascular development will have a dramatic impact on fetal growth and development, and thereby on neonatal mortality and morbidity. Recent work from our laboratories has focused on the effects of nutrient intake during pregnancy on placental growth and vascular development. Both nutrient restriction of the adult dam and overnourishment of the adolescent dam during pregnancy suppress placental cell proliferation and vascularity. Furthermore, placental expression of angiogenic factors and their receptors, factors that are known to affect vascular growth, are perturbed by level of nutrition. Studies in this area will lead to improved methods to manage nutritionally-compromised pregnancies.
journal_name
Domest Anim Endocrinoljournal_title
Domestic animal endocrinologyauthors
Redmer DA,Wallace JM,Reynolds LPdoi
10.1016/j.domaniend.2004.06.006subject
Has Abstractpub_date
2004-10-01 00:00:00pages
199-217issue
3eissn
0739-7240issn
1879-0054pii
S0739-7240(04)00090-6journal_volume
27pub_type
杂志文章,评审abstract：:The aim of this study was to differentiate canine adipose-derived mesenchymal stem cells (ADMSCs) into insulin-producing cells by using culture media with different compositions to determine the most efficient media. Stem cells isolated from the fat tissues close to the bitch uterus were distributed into 6 groups: (1)...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2020.106572
更新日期：2021-01-01 00:00:00
abstract：:The objective of the present studies was to determine the effect of cytokines on FSH-induced estrogen production by granulosa cells from small (1-5 mm) and large (> or = 8 mm) bovine follicles. FSH-induced estradiol production by granulosa cells from large follicles (expressed as pg estradiol/10(5) cells/24 hr) was no...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/0739-7240(94)90034-5
更新日期：1994-01-01 00:00:00
abstract：:Measurement of plasma osmolality (Posm) and plasma vasopressin (VP) concentration in response to hypertonicity is regarded as the gold standard for the assessment of VP release in polyuric conditions. Yet the interpretation of the VP curve as a function of Posm may be hampered by the occurrence of VP pulses. To determ...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2004.01.007
更新日期：2004-07-01 00:00:00
abstract：:Equine pituitary pars intermedia dysfunction (PPID) has been associated with reduced insulin sensitivity in comparison with younger adult horses; however, the difference in insulin sensitivity between horses with PPID and aged-matched controls has not been well characterized. The objective of the study was to determin...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2014.07.003
更新日期：2015-01-01 00:00:00
abstract：:The relationships among hepatic corticosteroid-binding globulin (CBG) mRNA expression and plasma concentrations of cortisol and CBG was evaluated in fetal pigs (n=7-14 per age) on days 50, 70, 80, 90, and 104 of gestation and postnatal pigs (n=8 per age) on days 1, 3, 10, 20, 30, and 40 following birth. In fetal pigs,...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(03)00055-9
更新日期：2003-10-01 00:00:00
abstract：:Glucocorticoids (GCs) are important environmental and maturational signals during intrauterine development. Toward term, the maturational rise in fetal glucocorticoid receptor concentrations decreases fetal growth and induces differentiation of key tissues essential for neonatal survival. When cortisol levels rise ear...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
doi：10.1016/j.domaniend.2016.02.014
更新日期：2016-07-01 00:00:00
abstract：:Assisted reproductive technologies, including in vitro embryo production (IVP), have been successfully used in animal reproduction to optimize breeding strategies for improved production and health in animal husbandry. Despite the progress in IVP techniques over the years, further improvements in in vitro embryo cultu...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
doi：10.1016/j.domaniend.2015.08.003
更新日期：2016-01-01 00:00:00
abstract：:The ability of gonadotropin-releasing hormone (GnRH) to synchronize ovulation and new follicular wave emergence before a "superovulatory Day 0" protocol was assessed in Santa Inês ewes. For estrus synchronization, a 60-mg medroxyprogesterone acetate sponge was inserted for 6 d. One day before sponge removal, 37.5-μg d...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2015.07.002
更新日期：2016-01-01 00:00:00
abstract：:The objective was to evaluate the effects of perinatal dexamethasone (Dex) treatment on postnatal growth in pigs. Experiment 1: 42 piglets were assigned according to birth weight and sex to receive either Dex (1 mg/kg body weight) or sterile saline (Control; equivalent volume) i.m. within 1h of birth. Body weights wer...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(02)00238-2
更新日期：2003-04-01 00:00:00
abstract：:Highly prolific sows often experience peripartum hypophagia, resulting in decreased production rate. Leptin, ghrelin, and resistin are known as feed intake-regulating hormones in many species, but it is yet unknown how feeding strategy and body condition will affect these hormones around parturition in sows. In the pr...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2013.04.003
更新日期：2013-07-01 00:00:00
abstract：:Eighteen crossbred boars, three siblings from each of six litters, were distributed randomly among three groups after weaning. The 'Natural long-day' group was housed in a standard room with windows, whereas the 'Artificial long-day' and 'Artificial short-day' groups were housed in light-sealed rooms and under an arti...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(00)00083-7
更新日期：2000-11-01 00:00:00
abstract：:The pituitary gland is a key endocrine organ responsible for growth and development. To get closer to understanding important molecular mechanisms at work in the bovine pituitary and identifying the core genes controlling growth, in the present study we have analyzed the transcriptome profiling of the pituitary glands...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2018.09.003
更新日期：2019-01-01 00:00:00
abstract：:The objective of the present study was to determine if dexamethasone (Dex; a potent synthetic glucocorticoid) treatment at birth would alter postnatal growth in neonatal pigs. Forty crossbred pigs were injected i.m. with either sterile saline (Cont; n = 10 males and 10 females) or Dex (1 mg/kg; n = 10 males and 10 fem...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(01)00107-2
更新日期：2001-08-01 00:00:00
abstract：:It has now been well documented that the normal and tumorous canine mammary glands can be extra-pituitary sites of substantial growth hormone (GH) synthesis. Until now, attempts to reproduce the GH synthesis in-vitro using canine mammary explants or mammary tumor cells have not been successful. Therefore, the response...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(01)00088-1
更新日期：2001-02-01 00:00:00
abstract：:The effects of somatostatin immunoneutralization on growth rate, growth hormone (GH) secretion and circulating insulin-like growth factor I (IGF-I) concentrations were investigated in chickens through the use of passive and active immunization techniques. Intravenous bolus injection of goat-antisomatostatin stimulated...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/0739-7240(87)90015-4
更新日期：1987-07-01 00:00:00
abstract：:A positive-feedback loop between luteal oxytocin and uterine prostaglandin F2 alpha (PGF) is a major signal for luteolysis in ruminants. Likewise, uterine PGF causes luteolysis in mares, but the involvement of oxytocin in this process is unclear. We wanted: 1) to determine if the oxytocin-neurophysin I (OT-NP I) gene ...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(99)00008-9
更新日期：1999-04-01 00:00:00
abstract：:Since its discovery in 1994, leptin, a protein hormone synthesized and secreted by adipose tissue, has been shown to regulate feed intake in several species including sheep and pigs. Although a nimiety of information exists regarding the physiological role of leptin in rodents and humans, the regulation and action of ...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
doi：10.1016/s0739-7240(01)00120-5
更新日期：2001-11-01 00:00:00
abstract：:beta-Adrenergic receptor (beta-AR) agonists increase muscle mass and decrease body fat in rodents and livestock. With oral administration, however, the effects of beta1-AR and beta2-AR can be different, depending on the species tested. We tested the effects of clenbuterol, a beta2-AR agonist, and ractopamine, a beta1/...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2003.08.004
更新日期：2004-01-01 00:00:00
abstract：:Lipoproteins are water-miscible macromolecules enabling the transport of lipids in blood. In humans, altered proportions of lipoproteins are used to detect and classify metabolic diseases. Obesity and obesity-related comorbidities are common in horses. The pathophysiology of obesity is poorly understood and likely mul...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2018.11.003
更新日期：2019-07-01 00:00:00
abstract：:The present study was conducted to evaluate changes in follicular fluid (FF) insulin-like growth factor binding protein (IGFBP) proteolytic activity and levels of steroids and IGFBP during follicular development in cattle. Estrous cycles of cows were synchronized with two injections of prostaglandin F2alpha (PGF) 11 d...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(01)00103-5
更新日期：2001-07-01 00:00:00
abstract：:The development and function of the immune system is regulated by neuroendocrine factors. Immune function may be divided into adaptive and natural immunity. Adaptive immune responses are driven by specific determinants of the antigen (epitopes), require 5-10 d to fully develop, and show an accelerated or memory respon...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
doi：10.1016/s0739-7240(98)00015-0
更新日期：1998-09-01 00:00:00
abstract：:In swine, colostrum production is induced by the drop of progesterone (P4) concentrations which leads to the prepartum peak of prolactin (PRL). PRL regulates mammary cell turnover and stimulates lacteal nutrient synthesis. P4 inhibits PRL secretion and downregulates the PRL receptor in the mammary gland. The aim of th...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2015.04.005
更新日期：2015-10-01 00:00:00
abstract：:Pituitary-dependent hyperadrenocorticism (PDH) in dogs is caused by a pituitary corticotroph adenoma. Although PDH is a common disorder in dogs, little is known about the underlying pathogenesis. In the pituitary glands of humans and mice, the pro-opiomelanocortin (POMC)-expressing cell lineages, the corticotrophs and...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2007.03.002
更新日期：2008-04-01 00:00:00
abstract：:The role of endogenous prostaglandin F2α (PGF) in the induction of luteolysis by exogenous PGF was studied by simultaneous inhibition of endogenous PGF with flunixin meglumine (FM). Groups were controls (n = 8), PGF treated (n = 8), and FM + PGF treated (n = 9). Treatments were given 10 d postovulation at hours 0, 8, ...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2017.10.007
更新日期：2018-04-01 00:00:00
abstract：:This study was performed to determine whether in dogs with pituitary-dependent hyperadrenocorticism (PDH) excessive release of adrenocorticotrophic hormone (ACTH) is accompanied by secretion of ACTH precursor molecules. In addition, we investigated whether the plasma ACTH precursor concentrations were correlated with ...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(02)00128-5
更新日期：2002-06-01 00:00:00
abstract：:This study examined the role of the adrenergic system in the regulation of growth hormone (GH) secretion in sheep. Intravenous infusion of noradrenaline (0.5 microgram/kg per min for 2 hr) totally suppressed plasma GH concentrations. Concomitant treatment of animals with the beta-adrenergic antagonist propranolol comp...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/0739-7240(94)90026-4
更新日期：1994-04-01 00:00:00
abstract：:In this prospective study 16 cats with diabetes mellitus were examined for concurrent acromegaly by measuring plasma growth hormone (GH) and insulin-like growth factor-I concentrations, and magnetic resonance imaging (MRI) of the pituitary fossa. Additionally, the effects of octreotide administration on the plasma con...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2008.07.004
更新日期：2008-11-01 00:00:00
abstract：:Severe feed restriction decreases serum insulin-like growth factor I (IGF-I) concentration in animals, and this decrease is thought to be due to reduced IGF-I production in the liver. The objective of this study was to determine whether feed deprivation also increases degradation of serum IGF-I and serum levels of IGF...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2008.07.003
更新日期：2008-11-01 00:00:00
abstract：:In small ruminants, testosterone and prolactin plasma concentrations show circannual fluctuations as an adaptation mechanism to their seasonal breeding behavior. Sperm resistance to the freezing-thawing process shows seasonal fluctuation throughout the year, with lower sperm freezability at the beginning of the breedi...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2019.06.004
更新日期：2020-07-01 00:00:00
abstract：:Reduction in fertility is well known to be possibly related to selenium deficiencies, even if target organ for selenium action is, at present, unclear. The present study was aimed to examine whether selenium directly influences granulosa cells. Bovine granulosa cells from different size follicles were used to investig...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(99)00059-4
更新日期：2000-01-01 00:00:00
