Abstract：
:In this prospective study 16 cats with diabetes mellitus were examined for concurrent acromegaly by measuring plasma growth hormone (GH) and insulin-like growth factor-I concentrations, and magnetic resonance imaging (MRI) of the pituitary fossa. Additionally, the effects of octreotide administration on the plasma concentrations of glucose, GH, alpha-melanocyte-stimulating hormone (alpha-MSH), adrenocorticotrophic hormone (ACTH), and cortisol were measured. Five cats were diagnosed with hypersomatotropism. The pituitary was enlarged in these 5 cats and in 2 other cats. Six cats that required a maximum lente insulin dosage >or=1.5 IU/kg body weight per injection had pituitary enlargement and 5 of these cats had acromegaly. Plasma concentrations of GH, ACTH, and cortisol decreased significantly after single intravenous administration of the somatostatin analogue octreotide in the acromegalic cats. The effect on GH concentrations was more pronounced in some of the acromegalic cats than in others. In the non-acromegalic cats only ACTH concentrations decreased significantly. In both groups plasma glucose concentrations increased slightly but significantly, whereas alpha-MSH concentrations were not significantly affected. In conclusion, the incidence of hypersomatotropism with concomitant pituitary enlargement appears to be high among diabetic cats with severe insulin resistance. Some of these cats responded to octreotide administration with a pronounced decrease in the plasma GH concentration, which suggests that octreotide administration could be used as a pre-entry test for treatment with somatostatin analogues.
journal_name
Domest Anim Endocrinoljournal_title
Domestic animal endocrinologyauthors
Slingerland LI,Voorhout G,Rijnberk A,Kooistra HSdoi
10.1016/j.domaniend.2008.07.004subject
Has Abstractpub_date
2008-11-01 00:00:00pages
352-61issue
4eissn
0739-7240issn
1879-0054pii
S0739-7240(08)00079-9journal_volume
35pub_type
杂志文章abstract：:Our aim was to correlate the individual variation in the milk yield response (MYR) of Holstein dairy cows to bovine somatotropin (bST), with changes in milk plasmin and plasminogen activities as well as with plasma hormone and metabolite levels. Thirty-two housed multiparous Holstein cows (90 +/- 3.8 days post partum)...
journal_title：Domestic animal endocrinology
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abstract：:Relatively little is known about the physiological roles of microRNAs (miRNAs) during follicular development. Previous evidence from in vitro studies suggests specific roles for a subset of miRNAs, including miR-21, miR-23a, miR-145, miR-503, miR-224, miR-383, miR-378, miR-132, and miR-212, in regulating ovarian folli...
journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/0739-7240(94)00021-r
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
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更新日期：1994-01-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
doi：10.1016/s0739-7240(98)00026-5
更新日期：1998-09-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2010.09.007
更新日期：2011-04-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2007.03.002
更新日期：2008-04-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2018.04.002
更新日期：2018-07-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2018.10.003
更新日期：2019-01-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(99)00082-x
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(96)00115-4
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
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journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/j.domaniend.2005.10.002
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
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journal_title：Domestic animal endocrinology
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
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更新日期：1990-01-01 00:00:00
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journal_title：Domestic animal endocrinology
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更新日期：2020-07-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
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journal_title：Domestic animal endocrinology
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更新日期：2020-07-01 00:00:00
abstract：:The aim of this study was to differentiate canine adipose-derived mesenchymal stem cells (ADMSCs) into insulin-producing cells by using culture media with different compositions to determine the most efficient media. Stem cells isolated from the fat tissues close to the bitch uterus were distributed into 6 groups: (1)...
journal_title：Domestic animal endocrinology
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更新日期：2021-01-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章
doi：10.1016/s0739-7240(99)00003-x
更新日期：1999-02-01 00:00:00
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journal_title：Domestic animal endocrinology
pub_type： 杂志文章,评审
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更新日期：1996-03-01 00:00:00
abstract：:N-methyl-D, L-aspartate (NMA) elicited secretion of growth hormone (GH)-releasing hormone from both the hypothalamic-preoptic area and the median eminence that were collected from boars. We suggest that the previously described increase in GH secretion that follows peripheral treatment of swine with NMA is attributabl...
journal_title：Domestic animal endocrinology
pub_type： 杂志文章
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更新日期：1999-11-01 00:00:00
