A primary care approach to Sjögren's syndrome. Helping patients cope with sicca symptoms, extraglandular manifestations.

abstract：:Readers are invited to submit questions relating to problem cases. Inquiries will be answered by qualified consultants and replies forwarded by mail promptly. Selected problems and solutions are published every month in this section. ...

journal_title：Postgraduate medicine

authors： Spitzer AR,Berberian DA,Moe JH

更新日期：1985-02-01 00:00:00

abstract：:The best way to detect Cushing's syndrome is to measure urinary free cortisol and to conduct a 1-mg dexamethasone suppression test. The best way to distinguish among the varieties of Cushing's syndrome is to measure plasma adrenocorticotropic hormone (ACTH). Urinary 17-ketosteroid and plasma testosterone determination...

journal_title：Postgraduate medicine

authors： Burke MD

更新日期：1981-01-01 00:00:00

abstract：:Anemia of chronic disease (ACD) is a prevalent condition commonly observed in patients with chronic infections, cancer, trauma, and inflammatory disorders. In this article, Dr Andrews examines new research findings that enhance the understanding of the pathophysiologic mechanisms of ACD. After a brief review of iron h...

journal_title：Postgraduate medicine

authors： Andrews NC

更新日期：2004-11-01 00:00:00

abstract：:Metformin is a first-line pharmacological treatment for patients with type 2 diabetes mellitus because of its favorable overall profile, including its glucose-lowering ability, weight-neutral effects, and low risk of hypoglycemia; however, gastrointestinal (GI) intolerance may limit use in some patients. Extended-rele...

journal_title：Postgraduate medicine

authors： Jabbour S,Ziring B

更新日期：2011-01-01 00:00:00

abstract：:GRATEFUL MED is a computer program for searching the medical literature, designed with the novice in mind. It contains an extensive list of medical subject headings, so the user does not have to page through an index of key words before starting the search. Because of its efficiency and ease of operation, the program ...

journal_title：Postgraduate medicine

authors： Schell CL,Rathe RJ

更新日期：1988-01-01 00:00:00

abstract：:The case described here illustrates the need to consider milk-alkali syndrome in the differential diagnosis of hypercalcemia, even in this age of histamine2 blockers and mucosal protectors. Thorough history taking and gastrointestinal workup help rule out alternative causes of hypercalcemia, such as cancer, hyperparat...

journal_title：Postgraduate medicine

authors： Newmark K,Nugent P

更新日期：1993-05-01 00:00:00

abstract：:Trigger points (TPs) in muscles of the lower torso associated with the spine are an important cause of low back pain. The quadratus lumborum is the muscle most commonly involved, but TPs located there are often overlooked because of inadequate physical examination techniques. TPs in the lower rectus abdominis refer pa...

journal_title：Postgraduate medicine

authors： Simons DG,Travell JG

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVES:Naloxone is indicated for reversal of opioid-induced respiratory depression. The objective of this study is to evaluate patterns of naloxone use in hospitalized patients. METHODS:Retrospective chart review at the University of California, San Diego Health. Subjects included adults ≥18 years old who were adm...

journal_title：Postgraduate medicine

authors： Yung L,Lee KC,Hsu C,Furnish T,Atayee RS

更新日期：2017-01-01 00:00:00

abstract：:The cultural drive to be thin can lead to eating disorders in many women and girls. In adolescent females with diabetes, the increased focus on eating and the weight gain associated with good glycemic control likely increase their susceptibility to abnormal eating. It is clear that nonspecified and subthreshold eating...

journal_title：Postgraduate medicine

authors： Hoffman RP

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:As the prevalence of peripheral artery disease (PAD) increases there is growing concern about the associated healthcare burden. This burden has not been well-characterized in high-risk patients with concurrent diabetes and/or acute coronary syndrome (ACS). The objective of this analysis was to assess comorbi...

journal_title：Postgraduate medicine

authors： Reed Chase M,Friedman HS,Navaratnam P,Heithoff K,Simpson RJ Jr

更新日期：2016-01-01 00:00:00

abstract：:Joint and soft-tissue aspiration and injection procedures are relatively easy to master once the physician has acquired an understanding of the techniques and subtleties of performing these procedures at certain sites. These techniques can be used to diagnose and treat many painful joint and soft-tissue conditions and...

journal_title：Postgraduate medicine

authors： Rifat SF,Moeller JL

更新日期：2001-03-01 00:00:00

abstract：:Pelvic inflammatory disease (PID) is a common infection in women of reproductive age. PID is actually a spectrum of disease, beginning with cervicitis and progressing to endometritis and eventually salpingitis. Sequelae include ectopic pregnancy, infertility, chronic pelvic pain, hydrosalpinx, and tubo-ovarian abscess...

journal_title：Postgraduate medicine

authors： Ault KA,Faro S

更新日期：1993-02-01 00:00:00

abstract：:Overuse syndrome and peripheral nerve entrapment syndromes arise in work situations in which the body is stressed beyond its limits by cumulative, repetitive trauma. These syndromes arise in some nonwork situations as well. When such an injury occurs, prompt diagnosis, treatment, and retraining aid in returning the em...

journal_title：Postgraduate medicine

authors： Mandel S

更新日期：1987-11-01 00:00:00

abstract：:Auscultation is the core of pediatric cardiovascular evaluation and should be performed according to a routine. The four heart sounds should be sought in order at their usual locations, with particular attention to the second sound because of its important diagnostic role in congenital cyanotic heart disease. The next...

journal_title：Postgraduate medicine

authors： Kulangara RJ,Strong WB,Miller MD

更新日期：1982-07-01 00:00:00

abstract：:Optimum therapy with psychopharmacologic agents in geriatric patients requires an appreciation of the elderly's increased predisposition to emotional disorders and their unique sensitivity to adverse drug-drug interactions. Although nonpharmacologic approaches should be considered, adjunctive use of psychoactive medic...

journal_title：Postgraduate medicine

authors： Cadieux RJ

更新日期：1993-03-01 00:00:00

abstract：:Diagnostic paracentesis with ascitic fluid analysis is critical to the accurate diagnosis and management of ascites. Recent advances have improved the evaluation of ascitic fluid, among them the serum-ascites albumin difference for discriminating between ascites caused by liver disease and ascites due to malignancy. T...

journal_title：Postgraduate medicine

authors： Marshall JB

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the proportion and the long-term prognostic significance of heart failure (HF) in sarcoidosis patients. METHODS:Data extracted from a large Israeli healthcare provider's database were used to study sarcoidosis patients and matched non-sarcoidosis controls since 2000 to 2016. The proportion of HF ...

journal_title：Postgraduate medicine

authors： Etinger R,Comaneshter D,Amital H,Cohen AD,Tiosano S

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To investigate the associations of major and subthreshold depression with all-cause, cardiovascular disease and stroke mortality, and the extent to which health behaviour, medical comorbidity and functional disability explained the associations. METHODS:A cohort of 1070 persons aged ≥60 with Geriatric Menta...

journal_title：Postgraduate medicine

authors： Ho CSh,Jin A,Nyunt MS,Feng L,Ng TP

更新日期：2016-09-01 00:00:00

abstract：:Treatment of primary breast cancer with excision of the tumor plus radiation is now an accepted alternative to mastectomy in women who desire breast preservation and have a suitable clinical presentation. Tumor size and location should be carefully considered before applying treatment with this method, the primary con...

journal_title：Postgraduate medicine

authors： Lichter AS

更新日期：1986-06-01 00:00:00

abstract：:Many patients who require evaluation for coronary artery disease are unable to undergo exercise stress testing because of physiologic or psychological limitations. Drs Vacek and Baldwin describe three alternative methods for assessment of cardiac function in these patients, all of which have high levels of diagnostic ...

journal_title：Postgraduate medicine

authors： Vacek JL,Baldwin T

更新日期：1989-09-15 00:00:00

abstract：:HIT is a common, potentially catastrophic syndrome. Awareness and early diagnosis allow effective therapeutic intervention. Ineffective strategies include stopping heparin only and starting warfarin early. Use of alternative anticoagulants is improving patient outcomes. Lepirudin, argatroban, and danaparoid each have ...

journal_title：Postgraduate medicine

authors： Rice L,Nguyen PH,Vann AR

更新日期：2002-09-01 00:00:00

abstract：:Preview Management of otitis media in children is a controversial matter: The basic questions of why, in whom, and how it should be treated are undergoing continual reassessment. In this article, Drs Shapiro and Bluestone provide answers to these and other questions, such as Why is treatment of acute otitis media just...

journal_title：Postgraduate medicine

authors： Shapiro AM,Bluestone CD

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVES:We investigated whether there was a higher prevalence of cognitive impairment (CI) and/or physical frailty (PF) in persons with diabetes compared to their non-diabetic counterparts, and the individual and combined impact of CI and PF on functional and mortality outcomes among diabetic older persons. METHOD:...

journal_title：Postgraduate medicine

authors： Thein FS,Li Y,Nyunt MSZ,Gao Q,Wee SL,Ng TP

更新日期：2018-08-01 00:00:00

abstract：:Primary care physicians have a crucial role in recognition of potentially emergent conditions in patients with known or suspected cancer. This task presents a significant challenge because the initial manifestations of these conditions are usually nonspecific. In most cases, therapy is far more effective when diagnosi...

journal_title：Postgraduate medicine

authors： Love N

更新日期：1990-12-01 00:00:00

abstract：:Management of patients with diabetes mellitus and chronic kidney disease (CKD) is a challenging task because multiple factors in each condition may impact the other. Glycemic control offers significant benefits in the prevention of diabetic kidney disease (DKD), but other associated morbidities are also important to a...

journal_title：Postgraduate medicine

authors： Ahmed Z,Simon B,Choudhury D

更新日期：2009-05-01 00:00:00

abstract：:Preview There is considerable overlap in features and treatment of chronic obstructive pulmonary disease and asthma. Why, then, is it necessary to distinguish between the two? As the authors explain, the two diseases have different causes, risk factors, and clinical courses. Correct diagnosis, described in this articl...

journal_title：Postgraduate medicine

authors： Subramanian D,Guntupalli KK

更新日期：1994-06-01 00:00:00

abstract：:Thymomas may be discovered during routine evaluation, through reported symptoms, or increasingly, during evaluation for myasthenia gravis. Histologic details of these tumors have little bearing on prognosis or evaluation of malignant potential. Malignancy is determined by evidence of invasion through the tumor capsule...

journal_title：Postgraduate medicine

authors： Cohen DJ

更新日期：1986-03-01 00:00:00

abstract：:Use of "designer drugs" has created a new dilemma for physicians. Generally, it is possible to recognize symptoms and signs of intoxication that fit a specific class of substances, such as amphetamine-like effects for the phenylethylamines and opioid effects for the fentanyl analogues. Designer compounds have crossed ...

journal_title：Postgraduate medicine

authors： Evanko D

更新日期：1991-05-01 00:00:00

abstract：:Septic shock is a multisystem disorder that represents the host's response to microbial invasion in its most fulminant form. One of the critical defects is a widespread inability to use available substrate for energy production. Endogenous mediators, particularly the cytokines, appear to play an essential role in this...

journal_title：Postgraduate medicine

authors： DePriest JL

更新日期：1989-09-01 00:00:00

abstract：:Ingested ethylene glycol is readily absorbed and metabolized into toxic metabolites that can cause CNS depression, cardiopulmonary failure, and renal failure. Thorough history taking, physical examination, and laboratory testing are essential for diagnosis. Careful differential diagnosis is important because symptoms ...

journal_title：Postgraduate medicine

authors： de Chazal I,Houghton B,Frock J

更新日期：1999-10-01 00:00:00