Nonmastectomy treatment of breast cancer. Current status of excision plus radiation.

abstract：:Exercise-induced asthma can appear as one of many forms of airway hyperreactivity or as a unique clinical entity. Simple spirometry confirms the suspected clinical diagnosis in most instances, although more sensitive measurements of airway obstruction may be required. In general, the asthmatic need not restrict physic...

journal_title：Postgraduate medicine

authors： Gerhard H,Schachter EN

更新日期：1980-03-01 00:00:00

abstract：:Osteoblasts are mesenchymal cells that play a key role in maintaining bone homeostasis; they are responsible for the production of extracellular matrix proteins, regulation of matrix mineralization, control of bone remodeling and regulate osteoclast differentiation. Osteoblasts have an essential role in the pathogenes...

journal_title：Postgraduate medicine

authors： Corrado A,Sanpaolo ER,Di Bello S,Cantatore FP

更新日期：2017-11-01 00:00:00

abstract：:Beta-blockers (beta-blockers) have demonstrated their value across the cardiovascular disease spectrum. Beta-blockers effectively lower blood pressure in patients with hypertension and provide symptomatic or mortality benefits in patients with heart failure and in post-myocardial infarction patients. However, despite ...

journal_title：Postgraduate medicine

authors： Kountz DS

更新日期：2009-01-01 00:00:00

abstract：:As efforts to improve screening for colon cancer have increased, so has the importance of routine flexible sigmoidoscopy. However, the procedure is still underused, and about half of primary care physicians who recommend it refer their patients to other physicians. Increased use of this valuable screening tool is an i...

journal_title：Postgraduate medicine

authors： Davis PW,Stanfield CB

更新日期：1999-06-01 00:00:00

abstract：:Preview How can physicians make appropriate treatment decisions in substance abusers who have serious medical illness, especially when patients may not offer the information needed? Drs Westreich and Rosenthal summarize common physical findings that suggest abuse of specific substances. Recognizing these signs allows ...

journal_title：Postgraduate medicine

authors： Westreich LM,Rosenthal RN

更新日期：1995-04-01 00:00:00

abstract：:Coma is a common, life-threatening medical problem encountered by primary care physicians. The principles of emergency management mandate that adequate oxygenation, blood flow, and supplementation with thiamine and glucose be given to the brain before a thorough diagnostic evaluation is undertaken. Knowledge of the us...

journal_title：Postgraduate medicine

authors： Alguire PC

更新日期：1990-05-01 00:00:00

abstract：:All patients with chronic stable angina presumed to be due to coronary artery disease should undergo exercise stress testing early in evaluation for evidence of high-risk coronary disease. If the exercise stress test shows early positive findings, patients should undergo cardiac catheterization to exclude left main co...

journal_title：Postgraduate medicine

authors： Dohrmann ML

更新日期：1986-11-01 00:00:00

abstract：:The tools and methods of epidemiology, particularly the clinical trial, help guide the clinical practice of medicine. Dr Gorelick reviews the results of major clinical trials for prevention of transient cerebral ischemia and atherothrombotic stroke and assesses the effect of these findings on treatment. ...

journal_title：Postgraduate medicine

authors： Gorelick PB

更新日期：1989-12-01 00:00:00

abstract：:Since the introduction of estimated glomerular filtration rate (GFR), the number of patients with chronic kidney disease (CKD) has considerably increased. This is particularly true for elderly patients as the majority have a low GFR. Chronic kidney disease has a significant impact on a patient's outcome. We have revie...

journal_title：Postgraduate medicine

authors： Abdelhafiz AH,Tan E,El Nahas M

更新日期：2008-11-01 00:00:00

abstract：:Even healthy persons may experience some form of altitude illness when they hike or ski in high mountains. Therefore, it is imperative that those with compromised cardiac or pulmonary function take extra precautions by allowing time for ascent, by recognizing and accepting their limitations, and by descending promptly...

journal_title：Postgraduate medicine

authors： Houston CS

更新日期：1990-07-01 00:00:00

abstract：:Treatment of hypertension in African Americans has special challenges, including a lack of objective trial data on which to base decisions and differing benefits and responses than with other patients. However, adequate control is possible and should be the goal of treating physicians. This article describes current "...

journal_title：Postgraduate medicine

authors： Bakris GL,Ferdinand KC,Douglas JG,Sowers JR

更新日期：2002-10-01 00:00:00

abstract：:Although fairly common, syncope is a frightening symptom that can signal a serious underlying disease. The varying causes present a diagnostic challenge to the examining physician, who needs to assess whether referral for more specialized or invasive study is appropriate. The authors review common cases of syncope and...

journal_title：Postgraduate medicine

authors： Hopson JR,Kienzle MG

更新日期：1992-04-01 00:00:00

abstract：:Evaluation and diagnosis of obstructive lung disease call for careful history taking to distinguish asthma from chronic obstructive pulmonary disease (COPD). A history of atopy and intermittent, reactive symptoms points toward a diagnosis of asthma, whereas smoking and advanced age are more indicative of COPD. Clinica...

journal_title：Postgraduate medicine

authors： Martinez FJ,Standiford C,Gay SE

更新日期：2005-03-01 00:00:00

abstract：:Spirometry is a simple but underutilized test that is particularly well suited for office practice. With it, the physician can distinguish among different types of ventilatory impairment and follow the patient's course. It also permits detection of small-airway disease at an early stage, when measures to prevent devel...

journal_title：Postgraduate medicine

authors： Francis PB

更新日期：1978-01-01 00:00:00

abstract：:Venous thromboembolism is a serious and, often, asymptomatic complication of hip surgery. A reliable screening test is needed to detect thrombi early to prevent death from pulmonary emboli. Noninvasive screening tests were ineffective in our study of 453 patients. We recommend early use of ventilation/perfusion lung s...

journal_title：Postgraduate medicine

authors： Mitsunaga MM,Ferris EB 3rd,Kong AY,Kistner RL,Mayfield GW,Lindberg RF,Jones DA

更新日期：1986-09-15 00:00:00

abstract：:Patients with dyslipidemia receive a cardiovascular benefit from lowering low-density lipoprotein cholesterol (LDL-C). Atorvastatin is currently one of the most effective approved medications for lowering LDL-C, and has been shown to significantly reduce cardiovascular risk in many patient groups. However, even with s...

journal_title：Postgraduate medicine

authors： McKenney JM

更新日期：2012-01-01 00:00:00

abstract：:Hair loss is a common problem likely to be encountered by a clinical practitioner. The most frequent causes of hair loss in pediatric patients include tinea capitis, alopecia areata, traction alopecia, and trichotillomania. In the adult population, causes to be considered are alopecia areata and hair loss associated w...

journal_title：Postgraduate medicine

authors： Phillips JH 3rd,Smith SL,Storer JS

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:Opioids with abuse-deterrent properties may reduce widespread abuse, misuse, and diversion of these products. This study aimed to quantify misuse, abuse, dependence, and health resource use of extended-release morphine sulfate with sequestered naltrexone hydrochloride (ER-MSN; EMBEDA®), compared with non-abus...

journal_title：Postgraduate medicine

authors： Cicero TJ,Mendoza M,Cattaneo M,Dart RC,Mardekian J,Polson M,Roland CL,Schnoll SH,Webster LR,Park PW

更新日期：2019-04-01 00:00:00

abstract：:Objective: To examine the mean carotid intima-media thickness (CIMT) and potentially relevant determinants of increased CIMT in elders. Method: Stroke-free and cardiovascular disease-free residents aged ≥65 years were recruited in a low-income population in China. B-mode ultrasonography was performed to measure CIMT. ...

journal_title：Postgraduate medicine

authors： Yu X,Bian B,Huang J,Yao W,Wu X,Huang J,Wang J,Yang Q,Ning X

更新日期：2020-08-01 00:00:00

abstract：:Cluster headache is a syndrome of severe head and facial pain accompanied by autonomic abnormalities. Men are affected more frequently than women. Headaches occur daily during periods of susceptibility, which may be followed by periods of remission. The etiology of cluster headache is uncertain. Recent work suggests t...

journal_title：Postgraduate medicine

authors： Marks DR,Rapoport AM

更新日期：1992-02-15 00:00:00

abstract：:Several pathologic processes can disturb the complex structures of the eyelids and orbital tissues and the muscles that enable their proper function. Some disorders, such as entropion and ectropion, are usually acquired in later years from laxity of supporting structures. Blepharoptosis has a range of causes, from agi...

journal_title：Postgraduate medicine

authors： Lissner GS

更新日期：1985-12-01 00:00:00

abstract：:Despite cervical cancer being considered a preventable disease, it still remains the second most common malignancy in women worldwide, with a higher incidence in underdeveloped countries. Human papillomavirus (HPV) is considered the causative agent of cervical cancer. The major mechanisms through which HPV contributes...

journal_title：Postgraduate medicine

authors： Subramanya D,Grivas PD

更新日期：2008-11-01 00:00:00

abstract：:In addition to prolonged glucocorticoid therapy (not discussed here), at least five other conditions cause Cushing's syndrome. They are excessive corticotropin secretion by the pituitary gland (which results in Cushing's disease), ectopic production of corticotropin by malignant nonpituitary tumors, benign adrenal ade...

journal_title：Postgraduate medicine

authors： Felicetta JV

更新日期：1989-12-01 00:00:00

abstract：:Eradication of H pylori and cure of peptic ulcer disease are possible if effective regimens are used correctly. Treatment markedly improves clinical outcomes and significantly decreases cost of care. As primary care physicians take a larger role in management of these infections, they need to understand the importance...

journal_title：Postgraduate medicine

authors： Laine L,Fendrick AM

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:This study aimed to determine if there is an association between lipid levels, serum albumin, and C-reactive protein (CRP) levels in patients on dialysis. METHODS:Lipid profiles, albumin, and CRP levels were collected after a 12-hour fast from patients with end-stage renal disease (N = 105) who were on chro...

journal_title：Postgraduate medicine

authors： Bowden RG,Wilson RL

更新日期：2010-05-01 00:00:00

abstract：:Primary care physicians play a pivotal role in the early identification of patients with COPD. Early diagnosis, along with aggressive intervention, is the only way that the increasing morbidity and mortality of COPD can be reversed. Any patient with a history of smoking should undergo evaluation for the possibility of...

journal_title：Postgraduate medicine

authors： Doherty DE

更新日期：2002-06-01 00:00:00

abstract：:Treatment of asymptomatic diverticulosis is geared to the prevention of constipation, with vigilance for possible signs of complications. A bulky stool decreases colonic intraluminal pressures, probably lessening pain and the chance of development of new diverticula. Increased stool weight may be achieved by the addit...

journal_title：Postgraduate medicine

authors： Herrera AF

更新日期：1976-12-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used to treat inflammatory pain for decades. More recently, newer NSAIDs were developed to target the inducible isoform of cyclooxygenase (COX), COX-2, with the aim of reducing gastrointestinal toxicity. While the COX-2 selective inhibitors were effective...

journal_title：Postgraduate medicine

authors： Walker C,Biasucci LM

更新日期：2018-01-01 00:00:00

abstract：:Catecholamine stimulation increases the heart rate and the force of cardiac contraction. Cardiac output then increases, with a decrease occurring in total peripheral resistance due to smooth muscle dilation in the vascular beds of the muscle and heart, though there is constriction of the skin and viscera; this leads t...

journal_title：Postgraduate medicine

authors： Fox KM

更新日期：1988-02-29 00:00:00

abstract：:The fact that the national death rate from carcinoma of the colon and rectum has remained static over the past two decades is strong incentive for future investigation of measures to allow detection in its early and more favorable stage. Although no significant improvements in surgical techniques have afforded improve...

journal_title：Postgraduate medicine

authors： Bland KI,Garrison RN,Knutson CO

更新日期：1979-09-01 00:00:00