Determinants of carotid intima-media thickness in asymptomatic elders: a population-based cross-sectional study in rural China.

Abstract:

:Objective: To examine the mean carotid intima-media thickness (CIMT) and potentially relevant determinants of increased CIMT in elders. Method: Stroke-free and cardiovascular disease-free residents aged ≥65 years were recruited in a low-income population in China. B-mode ultrasonography was performed to measure CIMT. Results: A total of 1039 individuals (47.9% men) were recruited. The mean CIMT value was 0.60 (SD: 0.09) mm. The mean CIMT was 24.07 (SEM: 6.52) µm greater in men than in women (P < 0.001) and 28.29 (SEM: 7.47) µm greater in patients with hypertension than in those without hypertension (P < 0.001). Moreover, the mean CIMT increased by 1.53 (SEM: 0.49) µm for each 1-year increase in age (P = 0.002). However, the mean CIMT decreased by 5.55 (SEM: 2.40) μm and 6.45 (SEM: 2.62) μm for every 1-mmol/L increase in triglyceride concentration and the high-density lipoprotein cholesterol: low-density lipoprotein cholesterol ratio, respectively (P < 0.05). However, high triglyceride level was negatively associated with mean CIMT only among individuals without metabolic syndrome (P = 0.036). Discussion: These findings suggest that there is an urgent need to delay atherosclerosis progression and reduce the stroke burden by managing hypertension, especially for men. Moreover, to decrease the stroke burden in rural China, caution is advised regarding lipid-lowering treatment in elderly patients without metabolic syndrome.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Yu X,Bian B,Huang J,Yao W,Wu X,Huang J,Wang J,Yang Q,Ning X

doi

10.1080/00325481.2020.1757266

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

544-550

issue

6

eissn

0032-5481

issn

1941-9260

journal_volume

132

pub_type

杂志文章
  • When epilepsy masquerades as heart disease. Awareness is key to avoiding misdiagnosis.

    abstract::Autonomic neural impulses that accompany discharges during a seizure can cause a variety of cardiac manifestations, including cardiac arrhythmias, sudden death, anginal chest pain, neurogenic pulmonary edema, and symptoms of pheochromocytoma. Either generalized or focal seizures may generate such signs and symptoms. A...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716430

    authors: Kothari SS

    更新日期:1990-11-01 00:00:00

  • Diagnosing ascites: the value of abdominal paracentesis.

    abstract::Abdominal paracentesis is a useful and safe technique in the evaluation of ascites. The withdrawn ascitic fluid should be routinely analyzed for appearance, blood cell count, and amylase and total protein concentrations; examined cytologically; and cultured. Results should either substantiate the clinical diagnosis or...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1978.11714844

    authors: Babb RR

    更新日期:1978-05-01 00:00:00

  • The epidemic challenge of chronic kidney disease in older patients.

    abstract::Since the introduction of estimated glomerular filtration rate (GFR), the number of patients with chronic kidney disease (CKD) has considerably increased. This is particularly true for elderly patients as the majority have a low GFR. Chronic kidney disease has a significant impact on a patient's outcome. We have revie...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.11.1943

    authors: Abdelhafiz AH,Tan E,El Nahas M

    更新日期:2008-11-01 00:00:00

  • Domestic violence. Do you know when and how to intervene?

    abstract::Physicians must be alert to the possibility of abuse within the family and home. They should be well prepared to help victims begin the transition to a safer environment. An awareness of the prevalence of abuse and a high index of suspicion are the most effective clinical tools for assisting victims of domestic violen...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1996.07.11

    authors: Steiner RP,Vansickle K,Lippmann SB

    更新日期:1996-07-01 00:00:00

  • Educational needs in the diagnosis and management of pediatric functional constipation: a US survey of specialist and primary care clinicians.

    abstract:OBJECTIVES:The goal of this study was to identify opportunities among gastroenterologists and gastroenterology nurse practitioners (NPs)/physician assistants (PAs) for continuing medical education (CME) related to functional constipation. METHODS:An online, case-vignette survey was designed to identify and quantify pr...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2018.1464364

    authors: Barnes J,Coleman B,Hwang S,Stolic A,Bousvaros A,Nurko S,Salinas GD

    更新日期:2018-05-01 00:00:00

  • Functional assessment in older patients.

    abstract::Preview Practical assessment of the functional and support factors affecting quality of life in older patients should be an integral part of medical management. This approach allows physicians to focus on remediable problems that compromise patients' daily functioning and may hinder them from living independently. In ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1996.11946120

    authors: Paist SS 3rd,Jafri A

    更新日期:1996-05-01 00:00:00

  • Inflammatory bowel disease. Options in office management.

    abstract::Current therapeutic options make office management of the patient with uncomplicated left-sided ulcerative colitis or mild to moderate Crohn's disease quite feasible for the primary care physician. On the horizon are additional drugs that will enhance the physician's ability to treat patients with inflammatory bowel d...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700202

    authors: Schuman BM

    更新日期:1988-03-01 00:00:00

  • Decline in the prevalence of pandemic clones Spain23F-1 and Spain9V-3 among US fluoroquinolone-resistant Streptococcus pneumoniae TRUST Surveillance isolates since 2001.

    abstract::Fluoroquinolone-resistant variants of pandemic clones Spain(23F)-1, Spain(6B)-2, Spain(9V)-3, and Spain(14)-5 have been seen in various regions of the United States and the world, leading to the speculation that fluoroquinolone resistance among US Streptococcus pneumoniae may increase because of clonal spread. Using l...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2008.09.suppl52.283

    authors: Davies TA,Yee YC,Goldschmidt R,Sahm DF,Evangelista AT

    更新日期:2008-09-01 00:00:00

  • Pharmacologic therapy of asthma.

    abstract::Asthma is treated by avoiding the precipitants of symptoms, by a trial of hyposensitization (immunotherapy) if the precipitant cannot be avoided, and principally by pharmacologic therapy. Acute attacks have been most widely treated with epinephrine, but adrenergic aerosol bronchodilators and aminophylline are being us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714330

    authors: Ellis EF

    更新日期:1976-04-01 00:00:00

  • Chronic pelvic pain. Differentiating anatomic from functional causes.

    abstract::Patients with chronic pelvic pain are challenging, from both diagnostic and therapeutic viewpoints. At the pain clinic at the Medical College of Georgia School of Medicine, Augusta, we have discovered over the past 3 years that psychiatric disease is probably underrecognized in these patients and that physicians are o...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Nolan TE,Elkins TE

    更新日期:1993-12-01 00:00:00

  • Contemporary therapy for acne. What, when, and how to prescribe.

    abstract::The use of topical tretinoin (Retin-A) for comedonal lesions, benzoyl peroxide for inflamed papules and pustules, and topical or oral antibiotics for more severe or widespread disease gives excellent results for the majority of patients with acne. At present, oral isotretinoin (13-cis-retinoic acid) (Accutane) should ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698996

    authors: Greer KE

    更新日期:1985-05-01 00:00:00

  • Use of antiplatelet agents in patients with atherosclerotic disease.

    abstract::Platelets play a key role in the initiation of hemostatic mechanisms during vascular injury. When contemplating prescription of antiplatelet agents (APAs) for patients as primary prevention for cardiovascular events, the physician should carefully weigh the potential benefits of cardiovascular risk reduction with the ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2013.09.2694

    authors: Acharji S,Lakshmanadoss U,Rudzinski W,Stapleton DD,Kaluski E

    更新日期:2013-09-01 00:00:00

  • Viral infections in the elderly. The challenges of managing herpes zoster, influenza, and RSV.

    abstract::Viral diseases are an important cause of morbidity and mortality in elderly patients, whether they live in the community or in long-term care facilities. Management of viral infections in older adults is complicated by factors that include the infrequency or absence of common signs and symptoms of infection and advers...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.11.1687

    authors: Bader MS,McKinsey DS

    更新日期:2005-11-01 00:00:00

  • Diagnostic cardiac catheterization.

    abstract::Preview The risks associated with diagnostic cardiac catheterization have declined through the years, but the question remains as to which patients should be referred for the procedure. In this article, Drs Walder and Schaller examine present guidelines for different types of heart disease and also review qualificatio...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1995.11945967

    authors: Walder LA,Schaller FA

    更新日期:1995-03-01 00:00:00

  • Rocky Mountain spotted fever. When and why to consider the diagnosis.

    abstract::Rocky Mountain spotted fever, caused by a rickettsial organism transmitted by the bite of a tick, can be confused with many more common diseases. Diagnosis is made more challenging by the fact that treatment is most efficacious if begun before the second week of illness. Tetracycline and doxycycline are the most succe...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11704599

    authors: Fischer JJ

    更新日期:1990-03-01 00:00:00

  • Cataracts. Lifting the clouds on an age-old problem.

    abstract::Cataracts are the most common treatable form of reduced vision in older adults. Although the incidence of cataracts is high after age 65, careful history taking and clinical examination are essential to establish the diagnosis. Cataract surgery is medically indicated when the view to the retina is obscured or lens-ind...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1998.05.478

    authors: Trudo EW,Stark WJ

    更新日期:1998-05-01 00:00:00

  • Genetic causes and workup of male and female infertility. 3. Details of the clinical evaluation.

    abstract::In the evaluation of male and female infertility the history, family history, physical examination, and endocrine and gonadal functional evaluations are the most informative measures. The cause of the infertility is never found in some 17.5% of couples and in almost one fourth of males. In over one third of cases male...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1979.11715204

    authors: Opitz JM,Shapiro SS,Uehling DT

    更新日期:1979-07-01 00:00:00

  • SGLT2 inhibitors in patients with type 2 diabetes and renal disease: overview of current evidence.

    abstract::Chronic kidney disease (CKD) is a frequent complication of type 2 diabetes mellitus (T2DM) and is associated with poor clinical outcomes, including an increased risk of all-cause and cardiovascular mortality, as well as adverse economic and social effects. Slowing the development and progression of CKD remains an unme...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2019.1601404

    authors: Davidson JA

    更新日期:2019-05-01 00:00:00

  • Postpartum mood disorders. A startling contrast to the joy of birth.

    abstract::More than half of new mothers may be affected by mood disorders after childbirth. Possible causes and recommended management depend on the type of disorder and its severity. In this article, Dr Knops discusses recognition, prevention, and management of three types of postpartum mood disorders as well as the need for s...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701624

    authors: Knops GG

    更新日期:1993-02-15 00:00:00

  • A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes.

    abstract:OBJECTIVE:The objective was to assess the relative risk (RR) for cardiovascular (CV) events across all 8 randomized phase 2/3 trials evaluating saxagliptin in patients with type 2 diabetes mellitus. METHODS:Cardiovascular events (death, myocardial infarction [MI], stroke, revascularization procedures, and cardiac isch...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.3810/pgm.2010.05.2138

    authors: Frederich R,Alexander JH,Fiedorek FT,Donovan M,Berglind N,Harris S,Chen R,Wolf R,Mahaffey KW

    更新日期:2010-05-01 00:00:00

  • The coughing child. A primary care perspective.

    abstract::Cough in children, even in infants under 1 year of age, is a frequent problem in clinical practice. Many causes are possible and should be considered, but only a few are likely. In primary care, appropriate evaluation is based on skillful history taking. In an ostensibly healthy child or infant with recurrent episodes...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698430

    authors: Schneider AP 2nd,Daws WR,Adams RD

    更新日期:1983-09-01 00:00:00

  • Coughing up a stone. What to do about broncholithiasis.

    abstract::Broncholithiasis, a disease that is probably much more common than has been reported, is most often associated with pulmonary infections, for example, tuberculosis and histoplasmosis. Stones originate from calcified peribronchial lymph nodes that erode into the tracheobronchial tree, but lithoptysis occurs infrequentl...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700166

    authors: Haines JD Jr

    更新日期:1988-02-15 00:00:00

  • Chronic neck and shoulder pain. Focusing on myofascial origins.

    abstract::Chronic neck and shoulder pain is a complex, multifactorial problem. Often many months have passed since its onset. During this time the patient may have seen many physicians and tried many medications, some with abuse potential. Most patients are depressed and have lost their ability to cope with the stresses of dail...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698897

    authors: Grosshandler SL,Stratas NE,Toomey TC,Gray WF

    更新日期:1985-02-15 00:00:00

  • Hematuria. When is it cause for alarm?

    abstract::The urine of less than 3% of healthy persons shows more than three red cells per high-power field, which is about the limit of sensitivity of test strips for occult blood. Even minimal hematuria may herald serious problems and must be investigated. Common causes include infection, urethritis, and urethrotrigonitis (25...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699979

    authors: Brown DC

    更新日期:1987-09-15 00:00:00

  • Chronic pain. A pharmacologic review and behavior modification approach.

    abstract::Management of pain syndromes clearly requires a multidimensional approach and involves social, psychologic, and somatic factors. At the Behavioral Medicine/Pain Therapy Center of Jewish Hospital, St Louis, most patients significantly increase social and physical activity using the combined approach outlined. A majorit...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11697831

    authors: Bakris GL,Zorumski CF

    更新日期:1983-05-01 00:00:00

  • Adenocarcinoma of the prostate. Stage-by-stage treatment alternatives.

    abstract::The best treatment for adenocarcinoma of the prostate depends on the patient's age, general medical condition, life expectancy, and willingness to accept such side effects as impotence. Radical prostatectomy or full-dose radiation therapy are usually curative when cancer is confined to the gland. The technique of pros...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1988.11700490

    authors: Soloway MS

    更新日期:1988-11-15 00:00:00

  • Cardiovascular risk factors.

    abstract::Preview New information emerges almost weekly about the relative importance of one factor or another in the development of coronary artery disease. Yet controversies continue over which factor deserves the most emphasis. Dr Elliott presents a broad and, at times, humorous look at research into cardiovascular risk fact...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945892

    authors: Elliott WJ

    更新日期:1994-09-01 00:00:00

  • Diet and coronary heart disease. Helping patients reduce serum cholesterol level.

    abstract::Although coronary heart disease (CHD) remains the No. 1 cause of death in the United States, the CHD mortality rate has shown a recent decline. This has been attributed to lower fat consumption in the general population, with associated lower serum cholesterol levels. Thus, diet seems to be an important factor in cont...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698970

    authors: Fletcher DJ,Rogers DA

    更新日期:1985-04-01 00:00:00

  • Aspirin sensitivity. A distressing reaction that is now often treatable.

    abstract::Aspirin-induced hypersensitivity affects a substantial number of people, including 20% or more of asthmatic patients. A dramatic flare of symptoms occurs after indigestion of aspirin or a nonsteroidal anti-inflammatory drug, and symptoms can persist even after the agent is discontinued. Fortunately, aspirin desensitiz...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1991.11701086

    authors: Manning ME,Stevenson DD

    更新日期:1991-10-01 00:00:00

  • Intensive glycemic control and cardiovascular disease: are there patients who may benefit?

    abstract::Cardiovascular disease (CVD) is the major cause of morbidity and mortality in patients with type 2 diabetes mellitus (T2DM). Recent major publications, such as the Action to Control Cardiovascular Risk in Diabetes trial, the Advance in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation tria...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2011.11.2501

    authors: Chokrungvaranon N,Deer J,Reaven PD

    更新日期:2011-11-01 00:00:00