Cushing's syndrome. How to pinpoint and treat the underlying cause.

abstract：:This paper compares the antifungal activity and efficacy of itraconazole and terbinafine in vitro with their experimental activity and efficacy in vivo in patients with superficial fungal infections (tinea pedis and onychomycosis). Onychomycosis and tinea pedis are often treated with oral antifungals. With the introdu...

journal_title：Postgraduate medicine

authors： De Doncker P,Gupta AK

更新日期：1999-07-01 00:00:00

abstract：:Sjögren's syndrome is a chronic, systemic, autoimmune inflammatory disorder characterized by lymphocytic infiltration of exocrine glands, most notably the salivary and lacrimal glands. It results in loss of functional epithelium, diminished exocrine function, and gradual onset of dryness of the eyes, mouth, and other ...

journal_title：Postgraduate medicine

authors： Derk CT,Vivino FB

更新日期：2004-09-01 00:00:00

abstract：:In a series of 123 children with disorders of defecation, constipation was the main problem in 89 and fecal incontinence in 34. All but three of the latter also had constipation. The principal physical findings were abdominal protuberance with palpable stool in the bowel and the presence of a fecal mass in the rectal ...

journal_title：Postgraduate medicine

authors： Liebman WM

更新日期：1979-08-01 00:00:00

abstract：:Maternal peripartum complications continue to be a significant problem in the United States, even among previously healthy women. The problems include peripartum bleeding, infection, hypertension, and thromboembolic disease. Primary care physicians are often called upon to treat these conditions. An awareness of the a...

journal_title：Postgraduate medicine

authors： Ritter DC,deShazo RD

更新日期：1994-02-01 00:00:00

abstract：:Stroke is the most feared complication among patients with atrial fibrillation. Oral anticoagulation therapy with vitamin K antagonists (VKAs) has been the gold standard for stroke prevention for the past 60 years. However, VKA therapy has many downsides, including risk for bleeding, a narrow therapeutic window, and t...

journal_title：Postgraduate medicine

authors： Truffa AA,Lopes RD,Newby LK

更新日期：2013-03-01 00:00:00

abstract：:Pain is one of the most common problems for cancer patients, and its management is often hindered by barriers created by patients and physicians alike. By avoiding potential barriers and understanding the principles of pain management and drug selection and titration provided here by Dr Hartmann and colleagues, physic...

journal_title：Postgraduate medicine

authors： Hartmann LC,Zahasky KM,Grendahl DC

更新日期：2000-03-01 00:00:00

abstract：:Preview Several dermatoses are potentially fatal, and the mortality rate for some is quite high; prompt recognition and treatment are essential. Dr Gannon's succinct discussions of pemphigus vulgaris, necrotizing fasciitis, toxic epidermal necrolysis, Stevens-Johnson syndrome, toxic shock syndrome, and urticaria and a...

journal_title：Postgraduate medicine

authors： Gannon T

更新日期：1994-07-01 00:00:00

abstract：:Evidence from epidemiologic, lipid intervention, and coronary angiographic studies demonstrates the importance of high-density lipoprotein cholesterol (HDL-C) in coronary artery disease (CAD) risk. Data from these studies strongly support the measurement of HDL-C in all patients screened for CAD. Patients with low lev...

journal_title：Postgraduate medicine

authors： Lavie CJ,O'Keefe JH,Blonde L,Gau GT

更新日期：1990-05-15 00:00:00

abstract：OBJECTIVES:Naloxone is indicated for reversal of opioid-induced respiratory depression. The objective of this study is to evaluate patterns of naloxone use in hospitalized patients. METHODS:Retrospective chart review at the University of California, San Diego Health. Subjects included adults ≥18 years old who were adm...

journal_title：Postgraduate medicine

authors： Yung L,Lee KC,Hsu C,Furnish T,Atayee RS

更新日期：2017-01-01 00:00:00

abstract：:Preview Just when it appeared that diuretics were becoming obsolete in the attack against hypertension, they have come charging back to the fore. This is especially true in treatment of systolic hypertension in the elderly. The perspective on diuretics and their recommendations for administration have changed recently...

journal_title：Postgraduate medicine

authors： Cushman WC

更新日期：1993-08-01 00:00:00

abstract：:Fever of unknown origin (FUO) remains a challenging clinical problem despite recent advances in diagnostic tools and techniques. Because primary care physicians are often the first ones to encounter a case of FUO, it is important that they be familiar with the best strategy and steps for confronting this problem initi...

journal_title：Postgraduate medicine

authors： Amin K,Kauffman CA

更新日期：2003-09-01 00:00:00

abstract：:Preview New information emerges almost weekly about the relative importance of one factor or another in the development of coronary artery disease. Yet controversies continue over which factor deserves the most emphasis. Dr Elliott presents a broad and, at times, humorous look at research into cardiovascular risk fact...

journal_title：Postgraduate medicine

authors： Elliott WJ

更新日期：1994-09-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a frequent complication of type 2 diabetes mellitus (T2DM) and is associated with poor clinical outcomes, including an increased risk of all-cause and cardiovascular mortality, as well as adverse economic and social effects. Slowing the development and progression of CKD remains an unme...

journal_title：Postgraduate medicine

authors： Davidson JA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Hypoglycemia and fear of hypoglycemia threaten individuals' ability to work and drive. We studied the effect of hypoglycemia on the individual and society, with a focus on possible implications of new European union legislation on patients' continued ability to drive. METHODS:A cross-sectional survey of Dan...

journal_title：Postgraduate medicine

authors： Dømgaard M,Bagger M,Rhee NA,Burton CM,Thorsteinsson B

更新日期：2015-06-01 00:00:00

abstract：:Difficult or painful coitus is a symptom, not a pathologic entity. It may be caused by a congenital anomaly, an organic lesion, or a functional disorder of the vulva or vagina, or it may be psychic in origin. Although its cause can usually be determined relatively easily, a conditioned reflex created by a preexisting ...

journal_title：Postgraduate medicine

authors： Huffman JW

更新日期：1983-02-01 00:00:00

abstract：:Preview No physician would treat hypertension without monitoring blood pressure, but some treat bronchial asthma without objectively measuring pulmonary function. This empirical approach is inappropriate, according to the authors, who discuss key measurements that should be taken to assess disease status, guide therap...

journal_title：Postgraduate medicine

authors： Weiss SM,Petty TL

更新日期：1995-06-01 00:00:00

abstract：:Colonic cancer remains a major cause of death because diagnosis is usually delayed. Improved methods for earlier detection will maximize the patient's chances for survival. At present, surgery offers the greatest possibility of cure, but even in those instances where less than definitive resection is possible, there i...

journal_title：Postgraduate medicine

authors： Wallack MK,Rosato FE,Brown AS,Rosato EF

更新日期：1975-04-01 00:00:00

abstract：:Aspiration results from abnormal structure or from dysfunction during the oral, pharyngeal, or esophageal stage of deglutition. Chemically induced inflammation of the lungs and obstruction of the airways may ensue. Feeding and swallowing problems may occur at any age, but they are particularly prevalent in the elderly...

journal_title：Postgraduate medicine

authors： Khawaja IT,Buffa SD,Brandstetter RD

更新日期：1992-07-01 00:00:00

abstract：:Ovulatory dysfunctional uterine bleeding (DUB), a disease prevalent in the latter half of the reproductive years, is diagnosed when organic causes for bleeding have been excluded by clinical, laboratory, and surgical diagnostic means. Disordered prostaglandin metabolism within the endometrium explains most cases of DU...

journal_title：Postgraduate medicine

authors： Strickler RC

更新日期：1985-01-01 00:00:00

abstract：:Views and clinical practice on hormone replacement therapy (HRT) for postmenopausal women have varied widely over the last several decades. The 1990s showed a dramatic decline in prescribing and only recently are prescription rates increasing again. Use of HRT is first line for women suffering from the symptoms of men...

journal_title：Postgraduate medicine

authors： Beck KL,Anderson MC,Kirk JK

更新日期：2017-08-01 00:00:00

abstract：:Preview An elevated serum calcium level requires thorough investigation. Is hyperparathyroidism at the root of the abnormality? Malignant disease? Vitamin toxicity? In this article, Dr Kaye discusses clinical evaluation of hypercalcemia and outlines pharmacologic therapy, surgical intervention, and other treatment opt...

journal_title：Postgraduate medicine

authors： Kaye TB

更新日期：1995-01-01 00:00:00

abstract：:When a patient presents with involuntary weight loss, the etiologic considerations can be overwhelming. To plan a cost-effective workup, physicians need to be aware of the most common causes of weight loss and the tests that yield the most pertinent data. Drs Wise and Craig review the clinical studies on unintentional...

journal_title：Postgraduate medicine

authors： Wise GR,Craig D

更新日期：1994-03-01 00:00:00

abstract：:Preview The risks associated with diagnostic cardiac catheterization have declined through the years, but the question remains as to which patients should be referred for the procedure. In this article, Drs Walder and Schaller examine present guidelines for different types of heart disease and also review qualificatio...

journal_title：Postgraduate medicine

authors： Walder LA,Schaller FA

更新日期：1995-03-01 00:00:00

abstract：:Objective: Abnormal pro-inflammatory regulation of the immune system might contribute to the pathogenesis of hyperglycemia during pregnancy. We examined the correlations of neutrophil-lymphocyte ratio (NLR) and monocyte-lymphocyte ratio (MLR) with disease severity and assessed their predictive values. Methods: This re...

journal_title：Postgraduate medicine

authors： Wang J,Zhu QW,Cheng XY,Sha CX,Cui YB

更新日期：2020-11-01 00:00:00

abstract：:Preview The effects of waning ovarian function start before menstruation stops, and they can be medically important. What changes should women expect, and what preventive health measures can they take? When is oral contraceptive therapy appropriate? How can irregular bleeding and decreased vaginal lubrication best be ...

journal_title：Postgraduate medicine

authors： Bachmann AG

更新日期：1994-04-01 00:00:00

abstract：:The cultural drive to be thin can lead to eating disorders in many women and girls. In adolescent females with diabetes, the increased focus on eating and the weight gain associated with good glycemic control likely increase their susceptibility to abnormal eating. It is clear that nonspecified and subthreshold eating...

journal_title：Postgraduate medicine

authors： Hoffman RP

更新日期：2001-04-01 00:00:00

abstract：:Infections of the neck become life-threatening with airway or systemic involvement. The first step in successful management is early recognition by the initial examiner. Patient evaluation includes a thorough history and physical examination, laboratory studies, and if the patient's condition is stable, roentgenograph...

journal_title：Postgraduate medicine

authors： Beck HJ,McCaffrey TV

更新日期：1984-12-01 00:00:00

abstract：:Elderly patients should be evaluated closely before surgery. Problems commonly found in these patients (ie, hypertension, diabetes, and cardiac and pulmonary disease) should be sought with special care and treated before surgery is undertaken. Also, wound healing may be compromised, drug clearance and metabolism impai...

journal_title：Postgraduate medicine

authors： Nolan TE

更新日期：1992-02-01 00:00:00

abstract：:The goal of screening for colorectal cancer is to find early, asymptomatic cancers and adenomatous polyps that are 1 cm or more in diameter or that are villous or tubulovillous histologically. A study using fecal occult blood testing with rehydration and no sigmoidoscopy found that deaths from colorectal cancer can be...

journal_title：Postgraduate medicine

authors： Lush DT

更新日期：1994-07-01 00:00:00

abstract：:Asthma is treated by avoiding the precipitants of symptoms, by a trial of hyposensitization (immunotherapy) if the precipitant cannot be avoided, and principally by pharmacologic therapy. Acute attacks have been most widely treated with epinephrine, but adrenergic aerosol bronchodilators and aminophylline are being us...

journal_title：Postgraduate medicine

authors： Ellis EF

更新日期：1976-04-01 00:00:00