Mycoplasma hyopneumoniae: interaction with other agents in pigs, and evaluation of immunogens.

Abstract:

:Mycoplasmal pneumonia of swine causes considerable economic losses in porciculture. Diverse agents, such as environmental stress and infectious microorganisms, increase the possibility of infection, and the damage to pulmonary tissue when the infection is established. It is known that Mycoplasma hyopneumoniae has an important role in this disease, in addition to secondary microbial agents, such as Pasteurella multocida and Actinobacillus pleuropneumoniae. However, the characteristics of this disease in farms are well known. In this work we review the interactions among the different microorganisms involved and the immunological strategies utilized to control this disease. The interaction between Mycoplasma hyopneumoniae and P. multocida in experimental pneumonia was reported by us in conventional pigs. M. hyopneumoniae causes mild pneumonia, whereas P. multocida aggravates the pneumonia initiated by M. hyopneumoniae. The disease has been reproduced to test the efficacy of two immunogens, and can also be used to evaluate some antibiotics. A M. hyopneumoniae bacterine administered intraperitoneally conferred more protection than when it was used with adjuvant, although protection was not complete and colonization by M. hyopneumoniae was not prevented, as is claimed to have been the case with other vaccines.

journal_name

Arch Med Res

authors

Ciprián A,Cruz TA,de la Garza M

subject

Has Abstract

pub_date

1994-07-01 00:00:00

pages

235-9

issue

2

eissn

0188-4409

issn

1873-5487

journal_volume

25

pub_type

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