Abstract:
BACKGROUND:Recently, the Expert Committee of the American Diabetes Association proposed to decrease the lower limit for normal fasting plasma glucose (FPG) levels to 5.6 mmol/L. In this regard, the aim of this study was to determine the effect of lowering the criterion for normal FPG on the identification of subjects with impaired glucose tolerance (IGT) and metabolic syndrome (MS). METHODS:We carried out a cross-sectional analysis of a population-based study from Durango, Mexico. This study enrolled 844 apparently healthy men and nonpregnant women aged 34 to 64 years. Diagnosis of IGT was based on 2-h post-load plasma glucose concentration > or =7.8 mmol/L and <11.1 mmol/L, and MS by the definition of National Cholesterol Education Program. RESULTS:The diagnosis of IGT and MS was established in 161 (19.1%) and 190 (22.5%) individuals, respectively. Lowering the cut-off point of FPG from 6.1 to 5.6 mmol/L identified more subjects with IGT, 53/161 (32.9%) vs. 132/161 (82.0%) (p <0.0001). It also identified more subjects with MS, from 88/190 (46.3%) vs. 169/190 (88.9%) (p = 0.0001). Lowering of the FPG cut-off point to 5.6 mmol/L improved the positive likelihood ratio for identifying subjects with IGT from 1.91 to 2.55 and the negative likelihood ratio from 0.81 to 0.27. Lowering the FPG cut-off point to 5.6 mmol/L did not significantly change the positive likelihood ratio for identifying MS from 3.65 to 3.18 and improved the negative likelihood ratio from 0.61 to 0.15. CONCLUSIONS:Lowering the cut-off point of IFG to 5.6 mmol/L improves the predictive discrimination of IFG for identifying subjects with IGT or MS.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Guerrero-Romero F,Rodríguez-Morán Mdoi
10.1016/j.arcmed.2005.05.010subject
Has Abstractpub_date
2006-01-01 00:00:00pages
140-4issue
1eissn
0188-4409issn
1873-5487pii
S0188-4409(05)00232-8journal_volume
37pub_type
杂志文章abstract:BACKGROUND AND AIMS:Thyroid hormones exert important effects on heart remodeling through mir-208. The process may have a role in myocardial changes in chronic kidney disease where thyroid abnormalities are common. In this study the effect of T4 supplementation on left ventricle (LV) remodeling in 5/6 nephrectomized rat...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2013.11.005
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Estrogens exert profound effects on target tissues. These effects are mediated by two estrogen receptors (ER(alpha) and ER(beta)) that bind to specific DNA sequences in estrogen-dependent genes. Other molecules such as growth factors, transcription factors and some oncoproteins might interact with the estrog...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.03.030
更新日期:2005-07-01 00:00:00
abstract:BACKGROUND:Because of their lack of long-term viability, adrenal tissue transplants have shown limited success in alleviating the motor disturbances associated with experimental and pathologic striatal dopamine denervation. In this study, we examined how the graft placement site influences adrenal medulla transplant su...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00247-2
更新日期:2000-11-01 00:00:00
abstract::Acute myeloid leukemia (AML) is a clonal disorder defined by the accumulation of abnormally differentiated myeloid cells that are not mature; any myeloid lineage can be affected and the extent of maturation of the leukemia blasts can also vary. Because mature blast cells of AML have very limited proliferative capacity...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2003.08.007
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:Afternoon nap sleep was studied in 32 young male medical students who take customary naps to replace loss in nocturnal sleep. METHODS:From 16 subjects, a group called dreamers was formed, and the other 16 individuals were grouped as non-dreamers. Polygraphic recordings lasting 30 min were done at a fixed ti...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Coronary artery disease is the significant cause of morbidity and mortality today. The treatment of coronary artery disease is improving, but its prevalence is increasing. Both primary and secondary prevention measures are of vital importance. METHODS:In this study, vitamin C, total antioxidant status, malo...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(01)00381-2
更新日期:2002-05-01 00:00:00
abstract::Two hundred fifty women with hirsutism were studied, with a mean age of 25.5 years (ranging from 13 to 38 years). The evolution of hirsutism varied from 3 months to 13 years, being minimal in 82 patients (33%), mild to 101 (40%), moderate in 56 (23%) and severe in the remaining 11 women (4%). Polycystic ovary syndrome...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:This study aims to investigate the efficacy of fluoxetine and paroxetine on the levels of depression-anxiety, quality of life, disability, and metabolic control in type II diabetes mellitus (DM) patients. METHODS:The patients were first applied the Hospital Anxiety-Depression Scale (HADS). After a psychiatr...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.arcmed.2004.12.018
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND AND AIMS:Further cases of novel influenza A (H1N1) outbreak are expected in the coming months. Vaccination has been proven to be essential to control a pandemic of influenza; therefore, considerable efforts and resources have been devoted to develop a vaccine against the influenza A (H1N1) virus. With the cu...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2010.01.004
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND AND AIMS:Childhood acute lymphoblastic leukemia (ALL) is the leading cause of childhood cancer-related deaths worldwide. Multiples studies have shown that ALL seems to be originated by an interaction between environmental and genetic susceptibility factors. The ARID5B polymorphisms are among the most reprodu...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.12.003
更新日期:2016-11-01 00:00:00
abstract::Blood-brain barrier (BBB) disruption has been associated with several acute and chronic brain disorders such as Alzheimer's disease, Parkinson's disease and epilepsy. This represents a critical situation because damaged integrity of the BBB is related to the influx of immune mediators, plasma proteins and other outsid...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2014.11.010
更新日期:2014-11-01 00:00:00
abstract::Classical descriptions of the pathology of amebiasis portray the parasite as the cause of tissue damage and destruction, and in recent years a number of amebic molecules have been identified as virulence factors. In this review we describe a series of experiments that suggest a more complex host-parasite relation, at ...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2005.10.007
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND AND AIM:Currently, the number of patients with coronavirus disease 2019 (COVID-19) infection is increasing rapidly worldwide. In this study, we aimed to assess whether diabetes mellitus (DM) would increase the risk of severe infection and death in patients with COVID-19. METHODS:We systematically searched t...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析
doi:10.1016/j.arcmed.2020.07.005
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Many studies indicate that the production of reactive oxygen species (ROS) after renal ischemia/reperfusion (I/R) may initiate the cascade of cellular injury. It has been demonstrated that ozone oxidative preconditioning (OzoneOP) may prevent the damage induced by ROS and attenuate renal I/R injury. On the b...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.09.005
更新日期:2008-02-01 00:00:00
abstract::The communication discusses COVID-19 triggered reverse migration in India. India has witnessed the second largest mass migration in its history after the Partition of India in 1947, where more than 14 million people were displaced and migrated to India and Pakistan respectively, depending on their religious faiths. Th...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.06.003
更新日期:2020-10-01 00:00:00
abstract::Hué, a city of about 300,000 inhabitants in Central Vietnam, is known as a "hot spot" for diseases caused by Entamoeba histolytica and in particular for amebic liver abscess (ALA), thus representing an excellent site for studies on the epidemiology and treatment of E. histolytica infections. Accordingly, during the la...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.10.001
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Wind instrument playing requires a strenuous respiratory activity. Previous studies investigating effect of wind instrument playing on pulmonary function are equivocal. METHODS:In the present study, 34 male, non-smoker wind players in a military band were compared with 44 healthy non-smoker males by pulmona...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2005.09.015
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Oxidative and endoplasmic reticulum stresses contribute to the pathogenesis of β-cell dysfunction in diabetes mellitus. This study investigates the effect of isopulegol on the above stresses in HFD/STZ induced diabetic rats. METHODS:Animals in group I and II were placed in normal pellet diet and group II wa...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.02.001
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND AND AIMS:Identifying gene-environment interaction in the context of multiple environmental factors has been a challenging task. We aimed to use conditional inference tree (CTREE) to strata myocardial infarction (MI) risk synthesizing information from both genetic and environmental factors. METHODS:We conduc...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2017.12.001
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:We undertook this study to compare the effectiveness and safety of antenatal daily and weekly supplementation with iron, folic acid, and vitamin B(12) in healthy, pregnant women who were not anemic at gestational week 20. METHODS:Women with singleton pregnancies and blood hemoglobin (Hb) >115 g/L at gestati...
journal_title:Archives of medical research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.arcmed.2005.11.011
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND AND AIMS:An increasing number of studies have been published concerning meeting targets of clinical guidelines for different aspects of the diagnosis and treatment of patients with end-stage renal disease. Most of these studies have shown that guideline recommendations are not always satisfied, and results o...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2013.01.008
更新日期:2013-04-01 00:00:00
abstract::In this report we show the chromosomal changes seen in a group of 303 Mexican patients with de novo Acute Myeloblastic Leukemia (AML). Two hundred forty-two patients were diagnosed and treated at two hospitals affiliated with the Instituto Mexicano del Seguro Social (IMSS). These are the Centro Medico Nacional Siglo X...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::Intracellular communication is an essential process in both embryological development and for the maintenance of normal tissue physiology. We have established the presence of this type of communication between endothelial cells and vascular smooth muscle cells in man and have here investigated the close contacts betwe...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Genome-wide association studies recently found IGF2BP2 rs4402960 polymorphism associated with enhanced risk of type 2 diabetes mellitus (T2DM). Numerous studies have been published to replicate the association. However, results were inconsistent and inconclusive. To clarify the relationship of IGF2B...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析
doi:10.1016/j.arcmed.2011.08.001
更新日期:2011-07-01 00:00:00
abstract::The prevalence of antibodies against the repeat epitope of the circumsporozoite protein (cs) of the standard (PV210) and variant (PVK247) strain of Plasmodium vivax was determined by ELISA in 1170 sera from individual residents of seven localities of the Region Huasteca of San Luis Potosi, Mexico. The capture antigens...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:Adrenoceptors have been involved in the regulation of hepatocyte proliferation after partial hepatectomy, as well as in primary culture. This report characterizes alpha 1- and beta-adrenoceptor change during the time-course of liver regeneration in adult Wistar Kyoto rats. METHODS:Saturation binding assays ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-0128(98)00028-1
更新日期:1999-03-01 00:00:00
abstract::In contrast to the prophylactic HPV vaccines that exhibit great promise in reducing the burden of cervical cancer, there is limited progress towards the development of immune therapeutic strategies that would help those women who are already infected with high-risk HPV and do not benefit from the current vaccines. The...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2009.07.003
更新日期:2009-08-01 00:00:00
abstract::In this study we evaluated the usefulness of ferruginous bodies (FB) quantification in lung digest and histologic sections from 40 patients with a history of exposure to inorganic dusts. The patients were matched with 40 cases without occupational exposure. The samples of peripheral lung tissue were digested and all F...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Myocardial infarction (MI) is one of the most important diseases that has stimulated interest in understanding cardiac function recovery. SDF-1 is a chemotactic factor and a pro-angiogenic molecule; SDF-1 degradation is inhibited by dipeptidyl peptidase-4 (DPP4) inhibitors, such as vildagliptin. We investiga...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2019.07.004
更新日期:2019-04-01 00:00:00